• 임상간호연구
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• 제14권2호
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• pp.127-138
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• 2008

Purpose: To examine the effects of the environmental nursing intervention using eye-shields and earplugs on the incidence of delirium, environmental stress and sleep among the patients with open-heart surgery in the post-cardiac ICU(intensive care units). Method: This study was a non-equivalent control group non-synchronized design. The subjects consisted of 93 patients who received ICU care after the cardiac surgery. Among those, 32 subjects was assigned in one experimental group with eye-shields, 31 in the other experimental group with earplugs, and 30 in the control group. ICU delirium was measured by CAM-ICU, environmental stress by ICUESS, and sleep by two sleep scales developed by Oh, et al. and Kim. The data were analyzed by the SPSS 13.0 program including frequency, percentage, t-test, $x^2$ test, ANOVA and ANCOVA. Results: There are no statistically significant differences in the incidence of delirium among three groups (p=.139). The ICU environmental stress scores from the subjects of two experimental groups demonstrated lower (F=6.731, p=.002) than the control group. Also, the degrees of sleep pattern (p=.000, p=.000) and sleep satisfaction (p=.000, p=.000) were greater than those of the control group. Conclusion: Although the environmental nursing intervention using eye-shields and earplugs did not demonstrate the effects in decreasing the incidence of ICU delirium, it has affirmative effects in decreasing environmental stress and improving the quality sleep among the patients with open-heart surgery while they stay in ICU. Further nursing implications are discussed.

• 동의신경정신과학회지
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• 제22권3호
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• pp.13-22
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• 2011

Objectives : This study was to research the relationship between Hwa-Byung and Framingham coronary risk score(FRS), cardiovascular disease. Methods : 649 people participated in the community based cohort study in Wonju City of South Korea from July 2nd to August 30th in 2006. Educated investigators checked up systolic & diastolic blood pressure and surveyed Hwa-Byung Diagnostic Interview Schedule(HBDIS), cohort questionnaire about gender, age, smoking, diabetes. Blood sample was collected from participants to analyze total cholesterol, HDL-cholesterol. FRS was calculated from collected data. 10-year prediction of coronary heart disease was determined from FRS by using score sheet that is estimated by Wilson et al. Collected data were analyzed by the chi-square test. Results : 1. Low risk number of people was 18(52.9%) in Hwa-Byung group, 263(42.8%) in non Hwa-Byung group. p-value was 0.472. Difference of the two group was invalid. 2. The number of people below or equal to average 10-year prediction of coronary heart disease as gnder & age, Hwa-Byung group was 19(55.9%), non Hwa-Byung group was 412(67.0%). p-value was 0.251. Difference of the two group was invalid. Conclusions : There was no correlationship Between Hwa-Byung and 10-year prediction of coronary heart disease.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2023년도 임시총회 및 춘계학술대회
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• pp.53-53
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• 2023

Abeliophyllum distichum, one of the Korean endemic plant, is a significant pharmaceutical plant resource. A. distichum with phenylethanoid glycoside can use to regulate the development of cancer, DNA damage with radicals, and the generation of inflammatory mediators. In this study, we investigated whether the biomass, content of phenylethanoid glycoside, and growth rate of callus derived from A. distichum (cultivar Okhwang1, CAD) change in the absence or presence of plant hormones (2,4-Dichlorophenoxyacetic acid; 2, 4-D and 1-Naphthaleneacetic acid; NAA). The results showed that the best biomass, the growth rate of callus, and the contents of phenylethanoid glycoside were cultivated on Murashige and Skoog (MS) growth medium fortified with 1 ppm 2,4-D + 2 ppm NAA after 4 weeks. In a further study, CAD was cultivated on MS growth medium fortified with an elicitor (Methyl Jasmonate, MeJA). The results showed that CAD turned to brown color and fragile form with the elicitor. HPLC-PDA analysis revealed that the contents of phenylethanoid glycoside in the elicitor-treated group were higher than in the elicitor-non-treated group. These results are consistent with the findings of Arano-Varela H et al.,'s study which is that acteoside production can increase after the treatment of MeJA. Therefore, this study can be used to develop an effective and sustainable production of useful substances as an alternative to plant cultivation.

• Food Science and Biotechnology
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• 제18권3호
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• pp.630-635
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• 2009

This study was performed to analyze various antioxidants, to evaluate the antioxidative activities, and to measure the protective effect for gap junction intercellular communication (GJIC) to assess the functional potency of the cherry tomato. The ascorbic acid, lycopene, and ${\beta}-carotene$ were measured at $503.4{\pm}9.6$, $39.7{\pm}1.5$, and $7.4{\pm}0.3$ mg/100 g d.w., and ${\alpha}-$, ${\beta}+{\gamma}-$, ${\delta}-tocopherol$ contents were measured at $8.3{\pm}0.1$, $1.7{\pm}0.0$, and $0.1{\pm}0.0$ mg/100 g d.w., respectively. Cherry tomato extract using hexane/acetone/EtOH (2:1:1, CTE) exhibited a ABTS radical scavenging activity with an $IC_{50}$ value of $48.83{\pm}0.30\;{\mu}g/mL$. The cherry tomato protected against the inhibition of GJIC induced by $H_2O_2$ in WB-F344 rat liver epithelial cells, and the reduction in phosphorylated Cx43 was most clearly correlated with the concentration of CTE. These results demonstrated that the cherry tomato harbors a wealth of potent antioxidants and might be protect human body against the inhibition of the GJIC by toxic components.

• Clinical and Experimental Reproductive Medicine
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• 제22권2호
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• pp.171-181
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• 1995

Ovarian hyperstimulation syndrome(OHSS) is one of the well-known complication of controlled ovarian hyperstimulation(COH). Though there have been numerous measures to prevent the occurrence of OHS, it has not been completely preventable until now. The fluid shift from the intravascular space to the third space is due to decreased oncotic pressure of the serum. The objective of this study was to evaluate if IV administration of 20% albumin in those patients with OHSS risk can make prevention of severe OHSS. We retrospectively analysed 70 patients undergoing IVF-ET who had serum peak estradiol($E_2$) level of >2,500 pg/ml and/or the number of oocytes retrieved over 20. The treatment group(n=39) received albumin while the control group(n=31) did not. After 40 grams of human albumin diluted in 1,000 ml of 0.9% sodium chloride solution, the treatment group received half of the fluid during oocyte retrieval, the remainder in the recovery suite. The results were as follows; There were significant differences in the levels of serum peak $E_2$ and number of oocytes retrieved between the two groups(p<0.05). However, there were no significant differences in the incidence of OHSS and pregnancy rate or multifetal pregnancy rate. In conclusion, administration of albumin to OHSS risk patients did not reduce the rate of OHSS in IVF-ET. However, if we consider the fact that there were differences in the level of peak serum $E_2$ and oocyte numbers, further prospective study may be needed.

• 정보보호학회논문지
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• 제13권6호
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• pp.141-148
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• 2003

Staddon 등에 의해 제안된 취소 능력을 가진 Self-healing 키 분배 기법은 동적 그룹의 멤버들이 신뢰할 수 없는 채널 상에서 그룹 키를 설정할 수 있게 하며, 더욱이 그룹을 탈퇴하거나 가입하는 멤버들에 의한 공모 공격에 안전하다. 이 프로토콜에서 그룹 멤버는 몇 몇 패킷들을 잃어버린 경우에도 그룹 매니저에게 추가적인 전송을 요청하지 않고 이전에 받은 패킷들을 이용하여 여전히 그룹 키를 복구할 수 있다. 이 프로토콜에서 그룹 멤버의 저장량은 O($m^2$1og p)이고, 그룹 매니저에 의해 브로드캐스트되는 메시지 크기는 O((mt$^2$+mt)log p)이다. 여기에서 m은 세션의 횟수이고, t는 공모할 수 있는 최대 그룹 멤버의 크기이고, p는 암호적 키로 사용할 수 있는 충분히 큰 소수이다. 본 논문에서는 O(mlog p)의 저장량과 O((t$^2$+mt)log p)의 통신량으로 기존의 기법과 같은 목적을 달성할 수 있는 더욱 효율적인 취소 능력을 가진 Self-healing 키 분배 기법을 제안한다. 우리는 그룹 멤버와 매니저의 입장에서 추가적인 계산량의 증가없이 그룹 멤버의 저장량을 최적으로 줄이고 그룹 매니저에 의해 브로드캐스트되는 메시지 크기를 효율적으로 줄인다.

• 성인간호학회지
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• 제12권4호
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• pp.584-594
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• 2000

This study was the done to describe health behavior and determine affecting factors in middle aged women. The subjects of this study were 306 middle aged women, living in M city, during the period from June 28th to August. 31st 1999. The instruments for this study were Health Behavior Assesment tool developed by Kim (1998), Self esteem scale developed by Rosenberg(1965), the perceived health status scale by Lawston, et al.(1982), the Quality of life by Ro(1988), the attitude toward Climacteric symptom by Ji(1983). The data were analyzed using descriptive statistics, t-test, Pearson correlation coefficients and stepwise multiple regression. The result of this study are as follows; 1. The total mean score for Health behavior was 2.51(range 1-4). The mean scores on the subscale were 2.83 for nutrition, 2.81 for stress management, 2.71 for limitation of liking in the menstrual group, health behavior was 2.64. The mean scores on the subscale were 2.98 for nutrition, 2.85 for stress management, 2.82 for limitation of liking, 2.80 for energy conservation in the menopausal group, 2. The mean scores for cognitive-perceptual variables in the menstrual group were perception of health status: 2.61, quality of life: 3.17, self-esteem: 2.59, and attitude for climacteric symptom: 3.02. In the menopausal group the scores were perception of health status: 2.41, quality of life: 3.10, self-esteem: 2.62, attitude for climacteric symptom: 3.06. 3. Health behavior and self-esteem(r=.269, p=.000; r=.205, p=.042), attitude for climacteric symptom(r=.192, p=.005; r=.545, p=.000), quality of life(r=.385, p=.000; r= .195, p=.050) and health behavior were correlated positively, and the perception of health status and health behavior were correlated negatively(r=.-135, p=.050; r= -.207, p=.040 ) in the menstrual group and menopausal group. 4. Perception of health status, quality of life, age, self-esteem, job and marital status explained 33.7% of the variance for health behavior in the menstrual group; self-esteem and education explained 33.1% of the variance for health behavior in the menopausal group. In conclusion, health behavior should be considered when developing nursing strategies for middle-aged women, especially when dealing with perception of health status, quality of life, and self-esteem.

• Journal of Korean Neurosurgical Society
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• 제55권1호
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• pp.5-11
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• 2014

Objective : We evaluated pseudoprogression (PsPD) following radiation therapy combined with concurrent temozolomide (TMZ), and we assessed pseudoresponse following anti-angiogenic therapy for patients with recurrent disease using the Response Assessment of the Neuro-Oncology Working Group. Methods : Patients who were pathologically confirmed as having high-grade glioma received radiotherapy with concurrent TMZ followed by adjuvant TMZ. Bevacizumab (Avastin) with CPT-11 were used as a salvage option for cases of radiologic progression. Magnetic resonance imaging (MRI) was routinely performed 1 month after concurrent radiochemotherapy (CRT) and every 3 months thereafter. For cases treated with the bevacizumab-containing regimen for progressive disease, MRI was performed every 2 months. Results : Of 55 patients, 21 (38%) showed radiologic progression within 4 weeks after CRT. Of these patients, 16 (29%) showed progression at second post-CRT MRI (etPD) and five (9%) showed improvement (PsPD). Seven of thirty-four initially non-progressed patients showed progression at the second post-CRT MRI (ltPD). No difference in survival was observed between the etPD and ltPD groups (p=0.595). Five (50%) of ten patients showed a radiological response after salvage bevacizumab therapy. Four of those patients exhibited rapid progression immediately after discontinuation of the drug (drug holiday). Conclusion : Twelve weeks following treatment could be the optimal timing to determine PsPD or true progression. MRI with gadolinium enhancement alone is not sufficient to characterize tumor response or growth. Clinical correlation with adequate follow-up duration and histopathologic validation may be helpful in discriminating PsPD from true progression.

• 지구물리와물리탐사
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• 제2권3호
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• pp.149-153
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• 1999

본 연구는 한국석유공사가 셸사(화란)와 공동탐사를 하고있는 남콘손분지에 대한 3차원 탐사작업의 일환으로 실시되었으며 구조가 매우 복잡한 동지역에서의 탄성파층서 해석 사례를 소개하고자 한다. 지질구조가 복잡한 지역에서는 탄성파상이나 시퀀스 경계면 형태(lap-out pattern)가 탄성파 자료상에 잘 나타나지 않으므로 Exxon Group(Vail et at., 1977)등이 개발한 탄성파 층서 분석법의 한계점이 있다. 이러한 지역에서는 시추공의 층서분석 결과와 탄성파 Attribute 및 등층후도 등을 이용하여 탄성파 층서 분석을 실시할 수 있다. 연구결과 탄성파 Attribute는 시퀀스 및 시스템트랙면의 고퇴적 환경과 암상변화와 대비가 되며 등층후도 및 구조도를 사용하여 시스템트랙 내부의 층서변화와 대비가 가능하였다. 또한 Azimuth Attribute를 사용하여 탄화수소의 이동경로 등을 예측할 수 있었다. 이러한 층서분석 결과를 종합하여 저류암, 덮개암, 구조형성시기, 및 탄화수소의 이동경로 등에 대한 리스크를 계산하는데 이용하였다.

• Safety and Health at Work
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• 제14권3호
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• pp.250-258
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• 2023

The effectiveness of mindfulness techniques in addressing mental health conditions in workers is uncertain. However, it could represent a therapeutic tool for workers presenting with such conditions. Our objective was to assess the effects of mindfulness-based practices for workers diagnosed with mental health conditions. We conducted a systematic review of randomized controlled trials. Participants included were workers with a mental health condition. Interventions included any mindfulness technique, compared to any nonmindfulness interventions. Outcomes were scores on validated psychiatric rating scales. A total of 4,407 records were screened; 202 were included for full-text analysis; 2 studies were included. The first study (Finnes et al., 2017) used Acceptance and Commitment Therapy (ACT) associated or not with Workplace Dialogue Intervention (WDI), compared to treatment as usual. At 9 months follow-up, for the ACT group, depression scores improved marginally (standardized mean difference [SMD]: -0.06, p = 0.021), but anxiety scores were worse (SMD: 0.15, p = 0.036). Changes in mental health outcomes were not statistically significant for the ACT + WDI group. In the second study (Grensman et al., 2018), no statistically significant change in mental health scales has been observed after completion of mindfulness-based cognitive therapy compared to cognitive behavioral therapy. Substantial heterogeneity precluded meta-analysis. This systematic review did not find evidence that mindfulness-based practices provide a durable and substantial improvement of mental health outcomes in workers diagnosed with mental health conditions.