• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2011년도 추계학술대회 논문집
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• pp.264-270
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• 2011

The goal of this study is a stability evaluation through eigenvalue and rotor dynamics analysis of the vacuum pump. The vacuum pump used is a roots type pump, one of the dry middle vacuum pumps, is necessary at the procedure to produce semiconductor and display. The eigenvalue evaluation is solved by numerical analysis through using Modal test and 2D 3D models. Both the experiment and the analysis result are similar, the analysis result using 2D is more oculate the 3D model comparing with test result. So rotor dynamic evaluation is performed through using 2D model. Rotor dynamic evaluation used the campbell diagram and root locus map which were acquired by complex eigenvalue analysis. And we checked minimum clearance of vacuum pump composition between two rotors through unbalance response analysis. Thus, vacuum pump, the target object of this study, was evaluated to be operated stably.

• 한국산업보건학회지
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• 제5권1호
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• pp.59-67
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• 1995

현재 국내에서 원자흡광법에 의한 혈중연 분석은 분석선 283.3 nm에서의 $D_2$ 보정 방식을 이용한 흑연로 원자흡광법이 주로 이용되고 있으며, 일반적인 시료중 납에 관한 분석은 217.0 nm에서의 $D_2$ 보정 방식이 보편화되어 있다. 그러나 이들 방식은 바탕 보정에 제한성 때문에 새로운 바탕 보정법에 대해 관심을 가지게 되었다. 그러던 중 1980년대 말부터 혈중연 분석자들은 연 분석에 있어 Zeeman effect 보정방식이 보다 좋은 결과를 나타낸다 하여 이 방법에 대하여 관심을 갖게 되었다. 따라서 본 연구는 국내 대부분의 혈중연 분석기관들이 보유하고 있는 $D_2$ 보정방식 (217.0과 283.3 nm)의 혈중연 측정결과를 편광 Zeeman effect 보정방식의 측정 결과와 비교함으로서 현재 사용 중인 기기 들의 측정결과의 타당성을 검토하기 위하여 시도하였으며 다음과 같은 결과를 얻었다. Zeeman형의 바탕보정 방식을 사용하는 기기의 결과를 편의상 1.00으로 하고, $D_2$ 형 보정 장치의 217.0 nm와 283.3 nm에서의 결과를 짝비교 (paired t-test)를 하였을 때 혈중연 농도가 $20.0{\mu}g/dl$ 이하인 경우에 0.92와 0.90으로 Zeeman형보다 낮은 값으로 분석되었으며 통계적으로 유의하였다.(P<0.001). $20.1-40.0{\mu}g/dl$인 군에서는 $D_2$ 보정방식의 결과간에 차이는 없었다. Zeeman 및 $D_2$ 보정방법에서는 혈중연 증가에 따른 바탕보정장치의 변동이 적었고 혈중연 이외의 다른 금속 즉, 철, 구리, 아연에서는 바탕보정장치에 관계없이 철은 역상관인 것으로 나타났으며, 구리와 아연은 정상관을 갖는 것으로 나타났다. 연구 결과로 미루어보아 두방법간의 차이가 없으므로 혈중연 분석에 있어서 Zeeman형 바탕보정 장치를 사용하거나 $D_2$ 바탕보정 방식(217.0, 283.3nm)의 기기를 사용하여도 무난할 것으로 생각된다.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2002년도 Proceedings of International Symposium on Remote Sensing
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• pp.880-884
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• 2002

According to the development of computer technology, especially in 3D graphics and visualization, the interest for 3D GIS has been increasing. Several commercial GIS softwares are ready to provide 3D function in their traditional 2D GIS. However, most of these systems are focused on visualization of 3D objects and supports few analysis functions. Therefore in this paper, we design not only a spatial operation processor which can support spatial analysis functions as well as 3D visualization, but also implement a prototype to operate them. In order to support interoperability between the existing models, the proposed spatial operation processor supports the 3D spatial operations based on 3D geometry object model which is designed to extend 2D geometry model of OGIS consortium, and supports index based on R$^*$-Tree. The proposed spatial operation processor can be applied in 3D GIS to support 3D analysis functions.

• 약학회지
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• 제54권6호
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• pp.441-448
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• 2010

In present study, classification and quality control of Genus Polygonatum were developed using the isolated from Polygonati Odorati Rhizoma and Polygonati Rhizoma. 3 components were isolated from Butanol fractions of Polygonati Rhizoma, and 2 components were isolated from Hexane and Butanol fractions of Polygonati Odorati Rhizoma. All the components were obtained using silica gel and ODS column chromatography. The compounds were identified as adenosine, 14-hydroxylfurost-5-ene-3-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}2$)-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}4$)-O-${\beta}$-D-galactopyranosyl-26-O-${\beta}$-D-glucopyranoside, 22-O-methyl-14-hydrocxyfurost-5-ene-3-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}2$)-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}4$)-O-${\beta}$-Dgalactopyranosyl-26-O-${\beta}$-D-glucopyranoside, ${\beta}$-Sitosteryl-3-O-${\beta}$-D-D-glucopyranoside, 14-hydoxylfurost-5-ene-3-O-${\beta}$-Dglucopyranosyl-($1{\rightarrow}2$)-O-[${\beta}$-D-xylopyranosyl-($1{\rightarrow}3$)]-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}4$)-O-${\beta}$-D-galactopyranoside through physicochemical data, spectroscopic methods ($^1H$-NMR, $^{13}C$-NMR, Mass) according references. The quality control of genus Polygonatum were conducted using HPLC quantitative analysis of 14-hydroxylfurost-5-ene-3-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}2$)-O-${\beta}$-D-glucopyranosyl-($1{\beta}4$)-O-${\beta}$-D-galactopyranosyl-26-O-${\beta}$-D-glucopyranoside, 14-hydoxylfurost-5-ene-3-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}2$)-O-[${\beta}$-D-xylopyranosyl-($1{\rightarrow}3$)]-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}4$)-O-${\beta}$-D-galactopyranoside in 30 samples collected throughout Korea and China. This method provided a tool for standardization of mix or misusing the commercial Odorati Rhizoma and Polygonati Rhizoma. As a result, contained quantity of 14-hydroxylfurost-5-ene-3-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}2$)-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}4$)-O-${\beta}$-D-galactopyranosyl-26-O-${\beta}$-D-glucopyranoside was measured $0.008{\pm}0.006%$ and 14-hydoxylfurost-5-ene-3-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}2$)-O-[${\beta}$-D-xylopyranosyl-(13)]-O-${\beta}$-D-glucopyranosyl-($1{\rightarrow}4$)-O-${\beta}$-Dgalactopyranoside was measured $0.026{\pm}0.012%$.

• Translational and Clinical Pharmacology
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• 제25권3호
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• pp.147-152
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• 2017

This study focused on the role of cytochrome P450 2D6 (CYP2D6) genotypes to predict phenotypes in the metabolism of dextromethorphan. CYP2D6 genotypes and metabolic ratios (MRs) of dextromethorphan were determined in 201 Koreans. Unsupervised clustering algorithms, hierarchical and k-means clustering analysis, and color visualizations of CYP2D6 activity were performed on a subset of 130 subjects. A total of 23 different genotypes were identified, five of which were observed in one subject. Phenotype classifications were based on the means, medians, and standard deviations of the log MR values for each genotype. Color visualization was used to display the mean and median of each genotype as different color intensities. Cutoff values were determined using receiver operating characteristic curves from the k-means analysis, and the data were validated in the remaining subset of 71 subjects. Using the two highest silhouette values, the selected numbers of clusters were three (the best) and four. The findings from the two clustering algorithms were similar to those of other studies, classifying $^*5/^*5$ as a lowest activity group and genotypes containing duplicated alleles (i.e., $CYP2D6^*1/^*2N$) as a highest activity group. The validation of the k-means clustering results with data from the 71 subjects revealed relatively high concordance rates: 92.8% and 73.9% in three and four clusters, respectively. Additionally, color visualization allowed for rapid interpretation of results. Although the clustering approach to predict CYP2D6 phenotype from CYP2D6 genotype is not fully complete, it provides general information about the genotype to phenotype relationship, including rare genotypes with only one subject.

• 한국건축시공학회지
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• 제22권3호
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• pp.269-280
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• 2022

건축물이 재산적 가치가 높아지면서, 국내외에서 실내 건축공사를 많이 하는 추세이다. 실내 건축공사는 물량 산출 및 적산까지 가능한 BIM 모델링의 기술까지 발전하였다. 실제 현장에서 반영하기에는 부담스러운 금액과 공정에 따라, 2D 도면과 3D 모델링을 통하여 진행하는 추세이다. 2D 도면과 3D 모델링은 서로 장단점이 존재하여 각 실내 건축공사에서는 시공 중 하자가 발생하고 있다. 실질적인 문제를 파악하기 위해 실내 건축공사의 현장 문제점, 2D 도면분석, 3D 모델링 분석, 사전 리스크 요인을 분석하였다. 문제점 분석 결과 1) 발주자와 의사소통 2) 노무자와 의사소통 3) 도면의 이해 등 여러 가지 문제점이 도출되었다. 본 연구에서는 이를 해결 할 수 있는 실내 건축공사 품질향상 체크리스트 제안을 하였다.

• International Journal of Computer Science & Network Security
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• 제24권2호
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• pp.178-188
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• 2024

In the near future, it is expected that there will be billions of connected devices using fifth generation (5G) network services. The recently available base stations (BSs) need to mitigate their loads without changing and at the least monetary cost. The available spectrum resources are limited and need to be exploited in an efficient way to meet the ever-increasing demand for services. Device to Device communication (D2D) technology will likely help satisfy the rapidly increasing capacity and also effectively offload traffic from the BS by distributing the transmission between D2D users from one side and the cellular users and the BS from the other side. In this paper, we propose to apply D2D overlay communication with cognitive radio capability in 5G networks to exploit unused spectrum resources taking into account the dynamic spectrum access. The performance metrics; throughput and delay are formulated and analyzed for CSMA-based medium access control (MAC) protocol that utilizes a common control channel for device users to negotiate the data channel and address the contention between those users. Device users can exploit the cognitive radio to access the data channels concurrently in the common interference area. Estimating the achievable throughput and delay in D2D communication in 5G networks is not exploited in previous studies using cognitive radio with CSMA-based MAC protocol to address the contention. From performance analysis, applying cognitive radio capability in D2D communication and allocating a common control channel for device users effectively improve the total aggregated network throughput by more than 60% compared to the individual D2D throughput without adding harmful interference to cellular network users. This approach can also reduce the delay.

• 통합자연과학논문집
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• 제9권1호
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• pp.1-9
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• 2016

Leucine rich repeat kinase 2 (LRRK2) is a highly promising target for Parkinson's disease (PD) that affects millions of people worldwide. A three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis was performed on a series of pyrrolopyrimidine-based selective LRRK2 kinase inhibitors. This study was performed to rationalize the structural requirements responsible for the inhibitory activity of these compounds. A reliable 3D-QSAR model was developed using comparative molecular field analysis (CoMFA) technique. The model produced statistically acceptable results with a cross-validated correlation coefficient ($q^2$) of 0.539 and a non-cross-validated correlation coefficient ($r^2$) of 0.871. Robustness of the model was further evaluated by bootstrapping and progressive scrambling analysis. This work could assist in designing more potent LRRK2 inhibitors.

• Imaging Science in Dentistry
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• 제37권1호
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• pp.27-33
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• 2007

Purpose : The research was done to investigate the effectiveness of 2D bony morphometry and microstructure of micro-computed tomography (micro-CT) on the osteoporotic bony change. We performed the bone morphometric analysis of proximal femur in ovariectomized rabbits with BMD and micro-CT examination. Materials and Methods : Twenty-one female (Newzealand, about 16 weeks old, 2.9-3.4kg) rabbits were used. Three rabbits were sacrificed on the day when experiment began (Baseline). The remaining 18 rabbits were divided into two groups. One group was ovariectomized bilaterally (OVX) and the other animals were subjected to sham operation (Sham). Bone specimens were obtained from the right and left femur of sacrificed rabbits. At intervals of 1, 2, 3, 5, 6 months respectively, BMD tests were performed on the proximal femur by using PIXlmus 2 (GE Lunar Co. USA), 2-dimensional bone morphometric analysis by custome computer program and 2D/3D bone structure analysis by micro-CT (Skyscan 1072, Antwerpen, Belgium). Statistical analysis was carried out for the correlation between bone morphometry, micro-CT and BMD Result : BV/TV, Tb.Th, Tb.N of micro-CT parameters showed higher values in sham group than OVX group. N.Nd/Ar.RI, N.NdNd, N.NdTm, N. TmTm, PmB/Ar.RI, 3-D BoxSlope of 2D morphometric parameters showed higher values in Sham group than OVX group. The micro-CT parameters of Tb.Sp, Tb.N were statistically significant correlated with BMD respectively. Several 2D morphometric parameters were statistically significant correlated with BMD respectively. Conclusion : Several parameters of 2D bony morphometry and micro-CT showed effective aspects on the osteoporotic bony change.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제2권3호
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• pp.205-208
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• 2013

일반적으로 이진패턴 변환은 조명 변화에 강인한 특성을 가지므로, 얼굴인식 및 표정인식 분야에 널리 사용되고 있다. 이에, 본 논문에서는 기존의 LDP(Local Directional Pattern)의 텍스처 성분을 개선한 MLDP(Modified LDP) 변환 영상에 2D-PCA(Two-Dimensional Principal Component Analysis) 알고리즘을 결합한 조명변화에 강인한 얼굴인식 방법에 대하여 제안한다. 기존의 LBP(Local Binary Pattern)나 LDP와 같은 이진패턴 변환들이 히스토그램 특징 추출을 위해 주로 사용되는 것과는 다르게, 본 논문에서 제안하는 방법은 MLDP 영상을 2D-PCA 특징추출을 위해 직접 사용한다는 특성을 갖는다. 제안 방법의 성능평가는 PCA(Principal Component Analysis), 2D-PCA 및 가버변환 영상과 LBP를 결합한 알고리즘을 사용하여, 다양한 조명변화 환경에서 구축된 Yale B 및 CMU-PIE 데이터베이스를 이용하여 수행되었다. 실험 결과, MLDP 영상과 2D-PCA를 사용한 제안 방법이 가장 우수한 인식 성능을 보임을 확인하였다.