• Title/Summary/Keyword: 2 order system

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DEVS Modeling with Hierarchical Planning: HRG-DEVS (계층적 계획을 이용한 이산 사건 시뮬레이션 모델링: HRG-DEVS)

  • Yi, Mi-Ra
    • Journal of the Korea Society for Simulation
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    • v.15 no.2
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    • pp.1-12
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    • 2006
  • As the needs of intelligent systems increase, there have been diverse approaches that combine artificial intelligence (AI) and simulation in the last decade. RG-DEVS, which is the basis for this paper, embedded AI planning techniques into the simulation modeling methodology of DEVS, in order to specify dynamically a simulation model. However, a hierarchy concept, which is used for various types of problem solving systems. is not included in the planning of RG-DEVS. The hierarchy concept reduces the computational cost of planning by reducing the search space, and also makes it easy to apply the hierarchical process flow of a target system to planning. This paper proposes Hierarchical RG-DEVS (HRG-DEVS) in an attempt to insert hierarchical planning capability into RG-DEVS. For the verification of the proposed modeling methodology, HRG-DEVS is applied to model the block's world problem of ABSTRIPS, which is a classical planning problem.

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Inhibitory actions of the antidepressant/antipanic drug phenelzine on brain GABA transaminase

  • Yoo, Byung-Kwon;Hong, Joung-Woo;Suk, Jae-Wook;Ahn, Jee-Yin;Yoo, Jeong-Suk;Lee, Kil-Soo;Cho, Sung-Woo;Choi, Soo-Young
    • Archives of Pharmacal Research
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    • v.19 no.6
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    • pp.480-485
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    • 1996
  • Brain GABA transaminase is inactivated by preincubation with antidepressant/antipanic drug pheneizine (${\beta}$ethylphenylhydrazine) (mixing molar ratio 10:1) at pH 7.4. The reaction of enzyme with phenelzine was monitored by absorption and fluorescence spectroscopic methods. The inactive enzyme was fully reconstituted by addition of cofactor pyridoxal-5-phosphate. This result implies that the blocking of 1 mol of pyridoxal-5-phosphate per enzyme dimer is needed for inactivation of the enzyme. The time course of the reaction is significantly affected by the substrate .alpha.-ketoglutarate, which afforded complete protection against the loss of catalytic activity. The kinetic studies shows that phenelzine reacts with the cofactor of enzyme with a second-order rate constant of $2.1{\times}10^3M^{-1}s^{-1}$. It is postulated that the antidepressant/antipanic drug phenelzine is able to elevate the neurotransmitter GABA levels in central nervous system by inhibitory action on GABA degradative enzyme GABA transaminase.

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Transformation of Brassica napus with Acid Phosphatase Gene (Acid Phosphatase 유전자 도입에 의한 유채의 형질 전환)

  • Lee, Hyo-Shin;Son, Dae-Young;Jo, Jin-Ki
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.17 no.3
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    • pp.285-292
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    • 1997
  • This study was conducted to obtain the transgenic Brnssica napus plants with tobacco Apase gene using the binary vector system of Agrobacteriurn fumefociens. The results obtained were summarized as follows: A repressible acid phosphatase gene of Saccharon~yces cerevisiae, pho105 was used for screening of tobacco Apase cDNA. In order to identify Apase gene in tobacco genome, Southern blot analysis was pcrformed and the Apase gcnc may be present as a single copy, or at most two or three copies, in tobacco genome. To isolate the tobacco Apase gene, tobacco cDNA library was constructed using purifed mRNA from -Pi treated tobacco root and the plaque forming unit of the library was 2.8 x $10^5$ pfu/m${\ell}$, therefore the library might cover all expressed mRNAs. Using pho5 as a probe. tobacco Apase cDNA was cloned, and restriction mapping and Southern blot analysis of cDNA insert were revealed that the 3.6 kb cDNA contained tobacco acid phosphatase cDNA. Plasmid pGA695 -tcAPl was constructed by subcloning tobacco Apase cDNA into the Hind site of pGA695 with 35s promoter which can be expressed constitutively in plants. The Brassica napus cotyledonary petioles were cocultivated with the ,4 grobacteriunz and transferred to the selection medium. The transformed and regenerated plants were transplanted to soil medium. Southern blot analysis was done on the transformed plants, and it was confirmed that a foregin gene was stably integrated into the genonies of B. nnpus plants.

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Induction of Leptin cDNA Expression in Esherichia coli Cells (대장균 세포에서 Leptin 유전자의 발현 유도)

  • 김은정;정인철;오상환;조무연
    • Journal of Life Science
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    • v.9 no.3
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    • pp.253-261
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    • 1999
  • Leptin gene, an obesity gene, has been known to involve in the regulation of food intake and body weight. It is also thought to be related to the glucose metabolism, insulin secretion and type II diabetes mellitus. Recently, the production of recombinant leptin protein has been attempted for the application in the treatment of obesity and the correction of hereditary obesity and type II diabetes. In the present study, leptin cDNA was cloned from mouse fat cells by RT-PCR and prokaryotic expression of leptin was attempted in order ot prepare a leptin-specific antigen. Immunization of a rabbit with the leptin-specific antigen into a rabbit resulted in the generation of leptin-specific antiserum that could be useful in the detection of leption expressed in various tissues. The sequence of leptin cDNA prepared in the present study wa identical to the previously reported one. Transformation of E. coli(DH5a) cells with the leptin cDNA-inserted translation vector, pGEX-4T-3-leptin followed by treatment with IPTG (0.1mM) resulted in the expression of a large amount of GST-leptin fusion protein with a molecular weight of 44 KDa as an inclusion body. Denaturation of the insoluble fusion protein by 8M urea, 6M guanidium-HCI or 0.1% 2-mercaptoethanol followed by a slow oxidation could not solubilize the inclusion body. The cell extract was subjected to SDS-PAGE and GST-leptin protein electroeluted from the gel was then injected into a rabbit subcutaneously for the immunization. Anti-GST-leptin rabbit antiserum which had a cross reactivity to the GST-leptin protein was generated. Leptin protein expressed in mouse brain and fat tissues was detected by Western blot immunodetection system using the antiserum generated in the present study.

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The Rational Regulation of Illegal & Harmful Information in Cyberspace (모바일 라이브 스트리밍 서비스의 불법·유해방송 근절에 관한 연구)

  • Song, You-Jin;Kim, Seung-In
    • Journal of the Korea Convergence Society
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    • v.8 no.9
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    • pp.231-236
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    • 2017
  • This study analyzes the characteristics of mobile live streaming service, the illegal and harmful information characteristics of mobile live streaming service for the purpose of eradicating illegal and harmful broadcasting, and shows illegal and harmful broadcast on the mobile live streaming service and eradication plan. First, we reviewed the mobile live streaming service, illegal and harmful broadcasts through literature review, and secondly surveyed illegal and harmful broadcasts of mobile live streaming services and their awareness and countermeasures. As a result, it is confirmed that the mobile live streaming service is illegal, harmful broadcasting exposure frequency is high, illegal, and harmful broadcasting exposure is caused by characteristics of real time broadcasting rather than user's. In order to eradicate the illegal and mobile information about the mobile live streaming service, it is necessary to fix the illegal service and harmful broadcasting reporting system, but the government has confirmed the requirements for regulatory measures. From a microscopic point of view, it will be necessary to investigate the illegal use of mobile live streaming services and the eradication of harmful information.

Study on Necktie Textile Design with Korean Traditional Motives (한국 전통문양을 응용한 넥타이 텍스타일디자인 연구)

  • Lee, Youn-Soon;Eum, Ji-Eun
    • Journal of the Korea Fashion and Costume Design Association
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    • v.10 no.2
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    • pp.149-161
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    • 2008
  • Since the use of textile has become more extensive and applied for various products, today, the importance of utility, ornament and civilization of textile is emphasized. Textile design should be able to satisfy the designer's creativity and his/her world of art. Moreover, it should be appropriate for the industrial technology circumstances, and taste of consumers. In Korea, traditional culture has been extremely valued, allowing people to be more interested in textile designs derived from traditional cultural. Therefore, designs inspired by the spirit and sense of traditional patterns has been used to develop modern textile designs. Prior research on products, however, show that cultural motive was insufficient, therefore, in this research the purpose is to design textiles and to develop Korean neckties, an essential component of men's attire, by adapting Korean traditional patterns. In order to conduct the research, first, numerous parers on Korean traditional patterns have been studied to select fundamental data about the development of necktie textile designs. Second, Korean traditional patterns were applied while following the target and concept, and two pieces of necktie textile designs have been suggested. Patterns had been designed by hand drawing and CAD system, they have been suggested as a portfolio. As a result, this article suggests new necktie designs utilizing Korean traditional patterns and, attempts to develop particular pattern designs, which have power to accommodate globalization and to express the special qualities of Korea.

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Improvement of Construction Management Process for the Site Manager in Small Scale Building Construction Project (소규모 건설프로젝트에서 현장관리업무 개선방안)

  • Lee, Da-Un;Yun, Seok-Heon
    • Journal of the Korea Institute of Building Construction
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    • v.18 no.1
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    • pp.81-87
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    • 2018
  • Since February 2017, site managers in small architectural projects are required by the revised building act. In order to address issues for site managers and to improve project efficiency, system improving methods are surveyed and proposed in this study. The key inspection items in the existing surveillance guidance manual were investigated, and the checklist for site managers for a small to medium sized construction site was analyzed. This study also tries to propose using web-based site management systems for improvement of the utilization of checklists. It is expected that these on-site management systems, along with BIM technology, will be able to monitor the small size building construction project in real time and effectively monitor the various problems occurring on-site.

A Study on Finding Ways to Reduce the Emission of Target Greenhouse Gases for Various Scenarios Utilizing the Building Energy Efficiency Rating (건물에너지 효율등급 제도를 이용한 시나리오별 목표 온실가스 저감방안에 관한 연구)

  • Bang, Young-Hyun;Kang, A-Ram;Park, Hyo-Soon;Suh, Seung-Jik
    • KIEAE Journal
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    • v.12 no.3
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    • pp.89-94
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    • 2012
  • The international community is paying close attention to the climatic changes caused by the meteorological anomalies. In response to such phenomena, after the adoption of the United Nations Framework Convention on Climate Change in 1992, efforts to actively respond to the meteorological changes are proliferating all over the world; even in the Republic of Korea, the issue to tackle the meteorological changes has emerged as a top-priority national agenda. In the year of 2008, after the declaration of the low-carbon, green-growth paradigm by the government, the UNFCCC COP15 has announced a 30% reduction target of the emission of the greenhouse gases by 2020 as compared to the "Business As Usual, BAU" and has also confirmed, as a commitment plan to achieve reduction in the emission of greenhouse gases, the reduction target of greenhouse gases for all sectors, industries and years. (26.9% for buildings) Since the construction of the new apartment houses in the year of 2001, the "Building Energy Efficiency Rating", has been applied to newly constructed building complexes, built in 2010; the accumulated emission reduction has been evaluated at around 450,000toe and the accumulated carbon dioxide emission reduction is at $826,000tCO_2$ And through the prediction of these values under various scenarios (New construction, new construction / expansion of existing uses, when transferred to 1stgrade), the effects on the degree of reduction of greenhouse gases by the increased certification of the Building Energy Efficiency Rating are an alyzed and it is our aim to express the importance of the certification system capable of carrying out a quantitative evaluation of the building energy in order to establish the strategy to reduce the emission of carbon dioxide.

TCAM Partitioning for High-Performance Packet Classification (고성능 패킷 분류를 위한 TCAM 분할)

  • Kim Kyu-Ho;Kang Seok-Min;Song Il-Seop;Kwon Teack-Geun
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.2B
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    • pp.91-97
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    • 2006
  • As increasing the network bandwidth, the threat of a network also increases with emerging various new services. For a high-performance network security, It is generally used that high-speed packet classification methods which employ hardware like TCAM. There needs an method using these devices efficiently because they are expensive and their capacity is not sufficient. In this paper, we propose an efficient packet classification using a Ternary-CAM(TCAM) which is widely used device for high-speed packet classification in which we have applied Snort rule set for the well-known intrusion detection system. In order to save the size of an expensive TCAM, we have eliminated duplicated IP addresses and port numbers in the rule according to the partitioning of a table in the TCAM, and we have represented negation and range rules with reduced TCAM size. We also keep advantages of low TCAM capacity consumption and reduce the number of TCAM lookups by decreasing the TCAM partitioning using combining port numbers. According to simulation results on our TCAM partitioning, the size of a TCAM can be reduced by upto 98$\%$ and the performance does not degrade significantly for high-speed packet classification with a large amount of rules.

Effect of Municipal Sewage Treatment Plant on Water Quality in Western Kangwon Area (강원 영서지역 하수처리장이 수질에 미치는 영향)

  • Huh In-Ryang;Choi Ji-Yong;Kim Yeong-Jin;Jeong Ui-Ho
    • Journal of Environmental Health Sciences
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    • v.31 no.4 s.85
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    • pp.235-240
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    • 2005
  • The effects of municipal sewage treatment plants on the water quality and effluent loading were investigated. BOD removal rates from Wonju, Hoengseong, and Hongcheon municipal sewage treatment plants were $88.9\%,\;80.6\%,\;90.7\%$ and T-P removal rates were $47.3\%,\;56.5\%,\;71.6\%,$ respectively. Also, BOD effluent leading from WonJu, Hoengseong, and Hongcheon treatment plants were 1,520 kg/day, 75 kg/day, 55 kg/day and T-P effluent loading were 203.9 kg/day, 4.2 kg/day, 4.0 kg/day, respectively. In terms of water quality distribution by distance of flow, BOD of the Seom river rapidly rose from 1.6 mg/l to 4.0 mg/l and T-P rose from 0.034 mg/l to 0.321 mg/l. Also BOD of the Hongcheon river showed a slowly rise from 1.1 mg/l to 1.4 mg/l and T-P from 0.011 mg/l to 0.026 mg/l. In conclusion, the effects of municipal sewage treatment plants on the water quality proved that T-P was higher than BOD. Consequently, in order to improve water quality, it is necessary to adopt an advanced sewage treatment system like nutrient removal.