• Asian-Australasian Journal of Animal Sciences
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• 제10권2호
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• pp.233-239
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• 1997

A mammary epithelial cell line (MAC-T) established as a model for lactation was utilized to identify and characterize effects of various hormones upon insulin-like growth factor binding protein secretion. Ligand and immunoblot analyses of conditioned media indicated that insulin-like growth factor binding protein-2 was secreted by MAC-T cells. Insulin-like growth factor-I stimulated insulin-like growth factor binding protein-2 secretion in a dose-dependent manner, but prolactin and bovine somatotropin did not alter insulin-like growth factor binding protein-2 secretion. Insulin increased and cortisol decreased insulin-like growth factor binding protein-2 secretion. Effects of insulin-like growth factor-I on insulin-like growth factor binding protein-2 secretion support previous studies using primary cultures of bovine mammary cells and bovine fibroblasts. Effects of cortisol and insulin on insulin-like growth factor binding protein-2 secretion may be explained by changes in protein synthesis. In addition, supraphysiological doses of insulin can cross-react with the insulin-like growth factor-I receptor and stimulate insulin-like growth factor binding protein-2 secretion. MAC-T cells provide a model system to study mechanisms that regulate local insulin-like growth factor-I bioactivity.

• 한국미생물·생명공학회지
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• 제31권4호
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• pp.395-399
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• 2003

본 연구에서는 S. hindustanus ATCC 31218로부터 선별된 변이주를 사용하여 배양조건이 nebramycin 주요 생산물인 factor 2, factor 4, factor 5', kanamycin A 등의 구성비율과 역가에 미치는 영향을 조사하였다. 실험결과, nebramycin의 factor들이 구성비율은 온도 및 배지보다는 배양액량, 교반속도 등에 의해 크게 영향을 받는 것으로 나타났다. 따라서 플라스크와 발효조의 산소전달속도를 각각 측정하여 factor 5' 생산의 최적 산소전달조건을 검토한 결과, $0.50 mMO_2$/min으로 배양시 factor 5'의 역가가 가장 높았으며 구성비율도 70% 이상을 나타내었다. 한편 $0.9 mMO_2$/min 이상으로 배양시는 factor 2의 역가와 구성비율이 현저히 감소한 반면 factor 2의 역가와 구성비율이 급격히 증가하였다. 한편 본 연구에 사용된 변이주 S. hindustanus YHT-0001는 factor 5'의 역가는 16.4배, factor 5'구성비율은 약 11% 향상된 균주로 확인되었다. S. hindustanus 발효시 공급되는 산소량은 단지 hydroxyl기와 아미노기의 존재유무에 따라 구조가 결정되는 factor 5', factor 4, kanamycin A의 hydroxyl기 생성을 위한 산소공여자로 역할뿐 만 아니라 배당체 구조에 차이를 보이는 apramycin 생합성과정에 영향을 크게 준다고 사료되었다.

• 한국의류학회지
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• 제24권2호
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• pp.277-285
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• 2000

The purpose of this study was to quantify the relationship between the sense of touch and mechanical properties of man-made leather. The first was to develop the five conversion equations which convert mechanical properties of man-made leather into five factor scores, which express five factors of the sense of touch(surface property, stretchiness, thickness & weight, thermal property(warmth & coolness), and moisture property(sticky & clingy)). The second was to develop the conversion equation which converts five factor scores into score of the sense of touch. Five factor scores were predicted by the following mechanical properties; surface property factor by log2HB and (log2HB)2, stretchiness factor by logEM, thickness & weight factor by logT, log2HB, logW, thermal property factor by logT, logHB, logSMd, and moisture property factor by logMMD, RC, RC2, (logEM)2, RT2. Subsequently, these five factor scores were converted into score of the sense of touch. The predictive abilities of the developed equations were satisfied.

• 한국조리학회지
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• 제14권2호
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• pp.99-114
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• 2008

The purpose of this study is to examine the relationships between each type of attitudes toward money and the attributes of choosing family restaurants. A self-administrated questionnaire was completed by 387 students, and data were analysed by frequency, factor, reliability and canonical correlation. Seven factors were obtained from factor analysis of attitudes toward money; Factor 1 "power", Factor 2 "obsession", Factor 3 "retention", Factor 4 "achievement", Factor 5 "anxiety", Factor 6 "distrust", and Factor7 "evaluation". The attributes of family restaurant choice were extracted into six factors: Factor 1 "quality of food", Factor 2 "restaurant event", Factor 3 "interior environment", Factor 4 "value of food", Factor 5 "convenience for approach", and Factor 6 "employees' service". Canonical correlation analysis showed three significant functions. Canonical function 1 showed that the attitudes of considering the power of money, its retention and achievement were indicated to have significantly positive relationships with the quality of food in the attributes of choosing family restaurants. Canonical function 2 showed that significantly negative relationships between distrust and restaurant events and convenience for approach. Canonical function 3 also showed that significantly positive relationships between obsession and anxiety and the interior of restaurants and employees' service, and significantly negative relationships between evaluation and the interior of restaurants and employees' service.

• 한국생활과학회지
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• 제17권2호
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• pp.305-313
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• 2008

This subject investigated visual evaluation of preference and fitness level of set-in sleeve in sleeve types(form)and studied suitable sleeve type at silhouette and targeted female students in twenties. The results of study were as follows: 1. Visual evaluation factors in set-in sleeve of sleeve types were selected 6 factors; the 1st factor is decorativeness, the 2nd factor is attractiveness, the 3rd factor was activeness, the 4th factor was feminine, the 5th factor was charming and 6th factor was a figural element. Decorativeness and attractiveness factors in visual evaluation of sleeve types were the most important level. 2. The visual evaluation differences of sleeve types in set-in sleeve were as follows; in the 1st factor, S and P2 were the most decorative sleeve type. in the 2nd factor, S, P2 and P3 are the most attractive sleeve type. in the 3rd factor, B and P3 were the most active sleeve type. in the 4th factor, L was the most feminine sleeve type. in the 5th factor, P1, L and P3 were charming sleeve type. in the 6th factor, P3 was evaluated that it shows narrowened shoulder sleeve types. 3. The analysis result of preference and wearing level in each sleeve types were as follows. 20's female university students like to wear S, P1, P2 and P3 sleeve types and the most favorite sleeve types are S, P2 and P3. 4. The analysis result of silhouette set-in sleeve in sleeve types; S, B and P2 in H-type silhouette, P2, S and P1 in A-type silhouette, B and P3 in O-type silhouette, L and P3 in X-types silhouette were show the most suitable sleeve types.

• 대한토목학회논문집
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• 제33권2호
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• pp.423-431
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• 2013

k-factor법은 합성교량의 설계에서 부정정 응력을 산정하는 방법으로 널리 사용되고 있다. 이 방법의 적정성을 평가하기 위하여 2경간 연속 강합성거더에 대하여 등가하중법과 비교하였다. k-factor법은 크리프에 대해서는 강재응력을 과소평가하고, 부모멘트 구간에서는 응력의 방향을 반대로 산정하며, 건조수축이나 온도차에 대해서는 단면변화를 고려하지 못하는 것을 확인하였다. 이 논문에서는 k-factor법의 정확성을 개선하면서, 계산의 편리성은 유지할 수 있는 j-factor법을 제안하였고, 그 효과를 2경간 연속 강합성거더에 적용하여 검증하였다.

• 대한한의진단학회지
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• 제13권2호
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• pp.34-44
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• 2009

Background : Currently, as a method of standardization of prescription, questionnaire for Buzhongyiqi-Tang[補中益氣湯] was developed, and which is a Objectives : The purpose of this thesis is to testify whether differentiation of Lao Juan Shang[勞倦傷] etiology is relative to mobility of gastric smooth muscle. Methods : The subjects(20 to 65 years old; 14 males, 46 females) were isolated from drinking alcohols for 24 hours before the experiment, and fasted for 8 hours, and measured for electrogastrography(EGG) and they filled out Questionnaire for Buzhongyiqi-Tang. Results : 1. Six factors from the factor analysis of Questionnaire for Buzhongyiqi -Tang were named and classified as Spleen-Qi deficiency syndrome factor [脾虛] (factor 1), Lung-Qi deficiency syndrome factor [肺虛] (factor 2), Working factor [習慣] (factor 3), Yin-Fire factor [陰火] (factor 4), Jung-Qi deficiency syndrome factor [中氣虛] (factor 5), and Stomach-Qi deficiency syndrome factor [胃虛] (factor 6). 2. As for the reliability of Questionnaire for Buzhongyiqi-Tang, we used Cronbach's alpha coefficient. Cronbach's alpha coefficient was 0.772 for the mean of the item-total. 3. Lung-Qi deficiency syndrome factor(factor2) had significant correlation with Bradygastria Time (r=-0.312, p<0.05). 4. Working factor(factor3) had significant correlation with Bradygastria Time (r=-0.329, p<0.05). 5. Yin-Fire factor(factor4) had significant correlation with Power Ratio (r=-0.328, p<0.05). Conclusions : It is shown that Bradygastria Time and Power Ratio tended to decrease against postprandial DP increased and postprandial frequency decreased in normal case.

• 한국도로학회논문집
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• 제13권4호
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• pp.211-220
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• 2011

최근 대중교통지향형개발(TOD)이 활발해지며, 역세권의 환경 변화를 통하여 국내의 대중교통 이용 증진을 시키기 위해서는 TOD 통합계획요소를 종합적으로 고려한 역세권 유형과 이용수요에 관한 실증분석이 전제되어야 향후 계획수립시 활용이 가능 할 것이다. 본 연구는 서울시 역세권을 대상으로 다양한 TOD 영향요인을 파악하고, 대중교통 이용수요와 연관성을 규명하기 위한 실증분석을 진행하였다. TOD의 대표적 요소인 Density, Diversity, Accessibility에 대한 자료를 수집하고, 요인분석과 회귀모형을 구축하였다. 분석결과 (1) 요인분석을 토대로 7개 영향요인이 도출되었으며, Factor 1(Diversity/토지이용복합도 (LUM)), Factor 2(Density/개발밀도수준), Factor 3(Accessibility/대중교통시설공급수준), Factor 4(Design/가로설계수준), Factor 5(Green/연계교통시설(보행자, 자전거), Factor 6(Design/지하철시설규모), Factor 7(Accessibility/대중교통운영수준)로 유형화되었다. (2) 요인-회귀분석 결과를 토대로 역세권 승하차 인원에 긍정적(+) 영향을 미치는 주요 요인은 Factor 1(Diversity : 토지이용복합도(LUM) 요인), Factor 3(Accessibility : 대중교통시설공급수준), Factor 2(Density : 개발밀도수준), Factor 5(Design/연계교통시설(보행자, 자전거), Factor 6(지하철시설규모)로 나타났다. 다음으로 역세권의 승하차 인원에 부정적(-) 영향은 Factor 7(Accessibility/대중교통운영수준)로 나타났으며, 가장 높은 영향력을 가지는 것으로 나타났다. 이는 지하철과 버스의 배차간격이 증가할 경우 이용수요가 감소하기 때문이다.

• Tuberculosis and Respiratory Diseases
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• 제85권3호
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• pp.221-226
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• 2022

Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation due to chronic airway inflammation and destruction of the alveolar structure from persistent exposure to oxidative stress. The body has various antioxidant mechanisms for efficiently coping with such oxidative stress. The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) is a representative system. Dysregulation of the Nrf2-ARE pathway is responsible for the development and promotion of COPD. Furthermore, COPD severity is also closely related to this pathway. There has been a clinical impetus to use Nrf2 for diagnostic and therapeutic purposes. Therefore, in this work, we systematically reviewed the clinical significance of Nrf2 in COPD patients, and discuss the value of Nrf2 as a potential COPD biomarker.

• 한국대기환경학회지
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• 제15권4호
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• pp.385-392
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• 1999

This study was carried out to investigate the constituents of inorganic ions of precipitation in Mokpo and Yeochon area from Jan. 1996 to Dec. 1997. The volume-weighted mean pH of precipitation was 5.7(4.8~7.8) at Mokpo, and 5.6(5.1~7.4) at Yeochon area, respectively. The non-seasalt(nss) anion concentrations were found in order of $nss-SO^{2-}_4>NO^-_3>nss-Cl^-$ at two areas. The portion of $nss-SO^{2-}_4;and;NO^-_3$ was 71~84% out of anions. The the non-seasalt cation concentrations were found in order of $NH^+_4>nss-Ca^{2-}>nss-Mg^{2+}>nss-K^-$ at two areas. The portion of $NH^+_4;and; nss-Ca^{2+}$ was 85~92% out cations. Compared regionally the year concentraton of $nss-SO^{2-}_4$, the result of Yeochon was 3 times higher than that of Mokpo in 1996, while the results of two regions were almost similar in 1997. The reason was that Yeochon was restricted area of the use of 0.5% sulfur B-C oil, controlled air pollution emission area, controlled semitotal amounts of air pollution emission area and partial operating of factories in 1997. There were no ions having high correlation with $H^+,;but;nss-SO^{2-}_4,;NO^-_3,;NH^+_4;and;nss-Ca^{2+}$ showed high correlation coefficient each other. It seems that these ions have little correlation with $H^+$ because they are washed out on binding state. Factor analysis showed that the first factor was complicated factor containing anthropogenic and soil resource, the second factor was sea-salt resource and the third factor was independent behavior of hydrogen at Mokpo. While, the first factor was complicated factor containing anthropogenic and sea-salt resource, the second factor was $Ca(NO_3)_2$ salt and the third factor was $NH^+_4;and;SO^{2-}_4$ synergied by resource and combination at Yeochon.