• International Journal of Highway Engineering
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• v.12 no.4
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• pp.79-86
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• 2010

This study deals with the roundabout installed at the diamond interchange. The goal is to analyze the relative effectiveness of roundabout to signalized intersection. In pursuing the above, this study gives the particular attentions to comparing the performances using VISSIM software. The main results analyzed are as follows. First, the single and double roundabouts are analyzed to have the rapid change of delay in the case of total entering vehicles of more than 2,400pcph for directional rate 10:5:5, 2,800pcph for 10:8:2, and 4,400pcph for 10:2:8. Second, the roundabouts are evaluated to be more effective than signalized intersection in the case of total entering vehicles of less than 4,000pcph for directional rate 10:5:5, and 4,400pcph for 10:2:8. In the case of directional rate 10:8:2, double roundabout of total entering vehicles less than 5,600pcph is analyzed to be more effective than signalized intersection. Finally, the performance of double roundabout is analyzed to be very similar to that of single roundabout in the case of total entering vehicles less than 4,400pcph. However, the double roundabout is evaluated to be more effective than single in the case of total entering vehicles more than 4,400pcph.

• Korean Journal of Clinical Laboratory Science
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• v.49 no.2
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• pp.128-134
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• 2017

Der p 1 and Der p 2 are essential allergens of house dust mite associated with the development of asthma. In the present study, we examined whether Der p 1 and Der p 2 induce a release of S100A8 and S100A9 in monocytes, which are involved in the regulatory mechanism of neutrophil apoptosis. We found that Der p 1 and Der p 2 significantly increased the secretion of S100A8 and S100A9 in normal monocytes. Moreover, S100A8 and S100A9 strongly suppressed the spontaneous apoptosis of normal and asthmatic neutrophils. The inhibitory effect of S100A9 was stronger than that of S100A8, and asthmatic neutrophils showed a higher inhibitory effect than normal neutrophils. S100A8 and S100A9 induced activation of Lyn, Akt, and ERK in a time-dependent manner. These findings elucidate the roles of Der p 1 and Der p 2 in the interaction between monocytes and neutrophils, as well as contributing to our knowledge of the pathogenesis of allergic diseases.

• Journal of The Geomorphological Association of Korea
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• v.25 no.4
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• pp.63-75
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• 2018

The lower marine terrace 1 and 2 surfaces distributed between Ulsan and Pohang coast in the southeastern coast of the Korean penninsula have been correlated with MIS 5e and 5a (or 5c) by amino acid dates, 14C dates, wide-spread tephra correlation and pollen analysis respectively. In this study, to test the reliability of the OSL method for the estimation of the numerical burial age of marine sediment deposits, we analyzed the samples from the marine terraces which have been known as typical marine terraces formed during MIS 5e and MIS 5a in the above-mentioned coast. The burial ages of the marine deposit of the lower marine terrace 1 and 2, with paleoshoreline altitudes of 18m to 19m and 10m to 11m respectively, both showed about the same age of 60 ka BP. The lower marine terraces 1 and 2, however, were divided into two terrace surfaces by a clear terrace cliff. Besides, the OSL dates of the lower and upper parts of the lower marine terrace 2 of the Bonggil coast showed the reversed burial ages. In the lower marine terrace 1 of the Sanhari coast, almost the same burial ages were derived from both the lower part (marine rounded gravel layer) and the upper part (terrestrial angular gravel layer) of the terrace deposit. Therefore, at the present time, judging from only the OSL dates measured in this study, it could be argued that the OSL method is not the best for the estimation of forming periods of the lower marine terraces 1 and 2 and their classification.

• The Korean Journal of Quaternary Research
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• v.18 no.1 s.22
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• pp.21-30
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• 2004

The Ilgwang Fault is NNE-striking, elongated 40 Km between Ulsan and Haeundae-ku, Busan in southeastern part of the Korean Peninsula. This paper si mainly concerned about the ages of the fault activities especially in the Quaternary, inferred from classification of geomorphic surfaces and trench excavation for the construction of Singori nuclear power plant. The geomorphic surfaces are classified into Beach and the Alluvial plain, the 10 m a.s.l. Marine terrace(MIS 5a), the 20 m a.s.l. Marine terrace(MIS 5e), the Reworked surface of 45 m a.s.l. Marine terrace(MIS 7 or 9) and the Low relief erosional surface. The Low relief erosional surface is distributed coastal side, the Reworked surface of 45m a.s.l. Marine terrace inland side by the Ilgwang Fault Line as the boundary line. But the former is above 10 m higher in relative height than the latter. The 20 m a.s.l. Marine terrace on the elongation line of the Ilgwang Fault reveals no dislocation. A site was trenched on the straight contact line with $N30^{\circ}E$-striking between the 10 m a.s.l. Marine terrace and the 20 m a.s.l. Marine terrace. Fault line or dislocation was not observable in the trench excavation. Accordingly, the straight contact line is inferred as the ancient shore line of the 10 m a.s.l. Marine terrace. The Ages of the Fault activities are inferred after the formation of the Ichonri formation - before the formation of the 45 m a.s.l. Marine terrace(220 Ka. y. B.P. or 320. Ka. y. B.P.). The Low relief erosional surface was an island above the sea-level during the formation of the 45 m a.s.l. marine terrace in the paleogeography.

• Journal of the Korean association of regional geographers
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• v.14 no.2
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• pp.173-188
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• 2008

In order to make comparative analysis of geomorphological changes caused by urban development, I surveyed the distribution of geomorphological resources of 'Daegu Innovation Town' development plan area. The results are as follow: (1) At the front of small valleys of back-mountains are formed small alluvial fans, and at the side of small valleys are distributed hills connected with back-mountains. (2) As small valley erode laterally hills, vertical bluffs and planner bedrock riverbed are formed, and in some riverbed are appeared mud cracks and ripple marks. (3) The depth of valley in alluvial fan of 'Sinseo District' is 7m. In Sinseocheon valley dissecting alluvial fan, fluvial terraces 2m high above riverbed are distributed. Those terraces were formed while alluvial fan was dissected after last glacial period.

• Korean Journal of Soil Science and Fertilizer
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• v.18 no.3
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• pp.289-296
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• 1985

To clarify the soil characteristics and genesis of the clayey terrace soils distributed in Yeongcheon (inland region) and Yeongil (coastal region), 9 typifying pedons including a recent local deposits were studied. The physico-chemical properties found were summarized as follows; 1. The contents of available water of the terrace soils were ranged from 12.0 to 20.3%. They were increased with increaseing clay content up to 35%, and then decreased at clay content of 35 to 55%, but were maintained about 12 to 13% when the clay content exceeds 55%. 2. The amount of water stable aggregates in the surface soils were ranged from 55.0 to 81.1%, and were low in cultivated upland where water erosion were accelerated while high in the paddy where the double cropping were practiced. The index of aggregate in cultivated upland were higher in the surface soils but the paddy soils were higher in subsoils. 3. The colloidal reactions checked by the differences between pH in $0.01N-Na_2SO_4$ and $H_2O$ indicate exchangeable acidity to exchangeable neutrality, which means a sort of Red-yellow soil forming process had been prevailed during genesis of the terrace soils. 4. Cation exchange capacity of the clayey terrace soils were averaged about 15.8-20.2me/100g of fine earth and 35.6-52.6me/100g of clay. The rates of base saturation were 32.7 to 57.6% and the rates decreased with increasing the elevations of terraces. 5. The activities of free iron oxides were 0.061 to 0.739 and the values decreased with increasing elevation while the crystallinity index of iron oxides positively correlated with elevations the values ranged from 0.067 to 0.537.

• Proceedings of the Mineralogical Society of Korea Conference
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• 2002.05a
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• pp.35-36
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• 2002

• Korean Journal of Clinical Laboratory Science
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• v.50 no.2
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• pp.177-182
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• 2018

This study examined the effects of zerumbone on monocyte migration. Monocytes are recognized as important mediators of various inflammatory diseases, and the possibility of controlling inflammatory diseases by regulating the monocyte functions, such as activity and mobility, has been reported. MCP-1, which is a chemokine with levels that increase upon inflammation, causes the migration of the monocyte cell line, THP-1. Migration occurred at a concentration of 10 ng/mL MCP-1, and the highest migration occurred at 100 ng/mL and 200 ng/mL. MCP-1-induced THP-1 migration decreased by more than 40% in the presence of zerumbone. The concentration of cAMP, an important secondary messenger of the CCR2 signaling pathway, the MCP-1 receptor, was increased in the culture medium after a zerumbone treatment. The concentrations of cAMP decreased significantly under the MCP-1 treatment condition only. On the other hand, an increase in cAMP was observed when zerumbone and MCP-1 were treated simultaneously. Erk phosphorylation induced by an MCP-1 treatment was also found to decrease with the zerumbone treatment. This study introduces the possibility of controlling inflammatory diseases through the function of zerumbone, which regulates the migration of monocytes.

• Journal of The Geomorphological Association of Korea
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• v.15 no.2
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• pp.1-9
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• 2008

This studied area is divided into the mountains and the valleys. The former is nearly consisted of the badland, the latter is consisted of alluvial plains in the valley, fluvial terrace at the side of the river, alluvial fans between mountains and river terrace. There are many tors, mushroom rocks, sugarloaves, weathering pits, castle coppies, columnar rocks, pinnacles, balanced rocks carved on tuff by means of erosion in the Chiricahua Nat'l Monument. Willcox Playa is alkalic crust where was lake in pleistocene epoch at the time wetter than present. Alkalic crust was made of Ca, Na, K etc. There are sand dunes around here where was lake side in the past. We found many kinds of fossils at the 2,000ft thick horizons of valley alluvium. Pediment and alluvium bordered at the base of Mt. Dragoon wavily. Exfoliation and spalling and sheeting resulted in boulders around here. Tucson is alluvial plain filled in thick 7,0000ft valley. Volcano, fault, erosion, alluvium were and are processing in this area.

• Tuberculosis and Respiratory Diseases
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• v.41 no.1
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• pp.11-19
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• 1994

Background: Mycobacterium tuberculosis is a facultative intracellular pathogen which persists and multiplies within macrophage. Competent cell mediated immunity by cooperation of both T lymphocyte and macrophage of the host is required to kill the Mycobacterium tuberculosis. But a precise understanding of the pathogenesis of tuberculosis infection in pulmonary alveolar macrophage has not been achived. Research on the macrophage's basic microbicidal mechanism has elucidated the importance of oxygen-dependent or oxygen-independent components. Oxygen dependent processing begins with the reduction of oxygen by NADPH oxidase and generation of superoxide. In this study, the oxidative metabolic status of blood monocyte and pulmonary alveolar macrophage in patients with active pulmonary tuberculosis was accessed and compared with that of healthy control subjects to know whether there was a basic difference in superoxide generation by mononuclear cells between two groups. Methods: Pulmonary alveolar macrophage was purified after performing BAL(bronchoalveolar lavage) through the bronchi of infected lesion by plastic adhesion method. Blood monocyte was purified by Ficoll-Hypaque method. Superoxide generation by blood monocyte and pulmonary alveolar macrophage was measured by ferricytochrome-C reduction method after either stimulated with PMA(phorbol myristate acerate) or non-stimulated states. We also measured the effect of pulmonary tuberculosis patient's serum on superoxide generation by monocyte. Results: 1) Generation of superoxide by alveolar macrophage obtained from patients with pulmonary tuberculosis was little higher than those of controls, and PMA enhanced the generation of 2) Generation of superoxide by blood monocyte obtained from patients with pulmonary tuberculosis was little higher than those of control(p>0.05), and PMA more enhanced the generation of superoxide in patientswith pulmonary tuberculosis than those in controls(p<0.02). 3) Patient's serum enhanced the generation of superoxide by blood monocyte obtained from patients with pulmonary tuberculosis and controls, but not in the case of PMA stimulated blood monocyte. Conclusion: The present study suggest that the phenomenon of M.tuberculosis escape the microbicidal action of macrophage was not result of suppressed superoxide generation by blood monocyte and pulmonary alveolar macrophage, rather there might be a factor to stimulate the generation of superoxide by blood monocyte in pulmonary tuberculosis patient serum, but the comparision with effect of control's serum on superoxide generation needs further elucidation.