• Title/Summary/Keyword: 1p/19q

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The Integer Factorization Method Based on Congruence of Squares (제곱합동 기반 소인수분해법)

  • Lee, Sang-Un;Choi, Myeong-Bok
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.12 no.5
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    • pp.185-189
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    • 2012
  • It is almost impossible to directly find the prime factor, p,q of a large semiprime, n=pq. So Most of the integer factorization algorithms uses a indirect method that find the prime factor of the p=GCD(a-b,n),q=GCD(a+b,n) after getting the congruence of squares of the $a^2{\equiv}b^2$(mod n). Many methods of getting the congruence of squares have proposed, but it is not easy to get with RSA number of greater than a 100-digit number. This paper proposes a fast algorithm to get the congruence of squares. The proposed algorithm succeeded in getting the congruence of squares to a 19-digit number.

Decay Rate and Nutrient Dynamics during Litter Decomposition of Quercus acutissima in Gongju and Jinju (공주와 진주지역에서 상수리나무 낙엽의 분해율 및 분해과정에 따른 영양염류 함량 변화)

  • Won, Ho-Yeon;Oh, Kyung-Hwan;Mun, Hyeong-Tae
    • Journal of Wetlands Research
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    • v.14 no.4
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    • pp.537-545
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    • 2012
  • Decay rate and nutrient dynamics during leaf litter decomposition of deciduous Quercus acutissima were compared between Gongju and Jinju for 33 months from December 2008 through March 2011. Percent remaining weight of Q. acutissima leaf litter after 33 months elapsed in Gongju and in Jinju was $41.2{\pm}0.4%$ and $28.3{\pm}0.6%$, and decay constant (k) was 0.39 and 0.61, respectively. Decomposition in Jinju was significantly faster than that in Gongju. This seemed to be related to higher temperature and precipitation in Jinju than those in Gongju during the experimental period. Initial C/N and C/P ratio of Q. acutissima leaf litter was 46.8 and 270.9, respectively. After 33 months elapsed, C/N and C/P ratios in Gongju decreased to 22.0 and 106.8, and those in Jinju decreased to 19.2 and 170.2, respectively. Initial concentration of N, P, K, Ca and Mg in Q. acutissima leaf litter was 8.31, 0.44, 4.18, 9.38, 1.37 mg/g, respectively. After 33 month elapsed, remaining N, P, K, Ca and Mg were 91.0, 85.4, 30.2, 47.9, 11.7% in Gongju, and 67.0, 54.2, 19.9, 30.0, 40.8% in Jinju, respectively. Except for Mg, remaining nutrients of decomposing leaf litter in Jinju were lower than those in Gongju. In case of N and P, initial immobilization was observed, however, only mineralization was observed in K, Ca and Mg during the whole experimental period.

Vegetation Structures of Stewartia koreana Forest in Mt. Jirisan (지리산 노각나무(Stewartia koreana)림의 식생구조)

  • Kwon, Hye-Jin;Gwon, Jae-Hwan;Jeong, Hye-Ran;Lee, Ji-Hye;Song, Ho-Kyung
    • Korean Journal of Environment and Ecology
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    • v.25 no.5
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    • pp.725-735
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    • 2011
  • This study was carried out to analyze the vegetation properties, soil characteristics, and ordination of Stewartia koreana community of Mt. Jirisan in Korea. The S. koreana community was classified into S. koreana-Quercus mongolica serrata community, S. koreana-Quercus mongolica community, and Typical community. In specific, S. koreana-Q. serrata community was classified into two subgroups such as Carpinus laxiflora subcommunity and typical subcommunity. The S. koreana community was found out to be located at an elevation of 409m to 1,604m. The Results of importance value on the S. koreana community consisted of the following in order: 75.47% of S. koreana, the highest, 21.83% of Q. serrata, 18.65% of Q. mongolica, 18.19% of Acer pseudosieboldianum, 10.56% of Rhododendron schlippenbachii, 10.36% of Styrax japonicus. In the targeted study sites, soil organic matter, total nitrogen, available phosphate, exchangeable potassium, soil moisture and soil pH were 3.15~39.1%, 0.37~11.7%, 0.9~45.4mg/kg, $0.09{\sim}1.48cmol^+/kg$, 19.28~55.47% and 4.08~5.65, respectively. The results of the correlation between communities and soil conditions of S. koreana community by DCCA ordination method are as follows: S. koreana-Q. serrata community was found in the highest elevation and followed in order S. koreana typical community, S. koreana-Q. serrata typical subcommunity, and C. laxiflora subcommunity.

Effect of Water Temperature and Body Weight on Oxygen Consumption Rate of Starry Flounder Platichthys stellatus (강도다리 Platichthys stellatus의 산소 소비율에 미치는 수온과 체중의 영향)

  • Oh, Sung-Yong;Jang, Yo-Soon;Noh, Choong Hwan;Choi, Hee Jung;Myoung, Jung-Goo;Kim, Chong-Kwan
    • Korean Journal of Ichthyology
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    • v.21 no.1
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    • pp.7-14
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    • 2009
  • The effect of water temperature (T) and body weight (W) on oxygen consumption of fasted starry flounder Platichthys stellatus was investigated in order to assess the metabolic response of this species at given conditions. The oxygen consumption rate (OCR) was measured under six different water temperatures (4, 7, 10, 13, 16 and $19^{\circ}C$) and at two different body weights (mean weight of fry group : 1.5 g; fingerling group : 37.4 g) at an interval of 5 minutes for 24 hours using a continuous flow-through respirometer. In each treatment three replicates were set up and a total 540 fish in fry groups and 90 fish in fingerling groups were used. The OCRs increased with increase of water temperature in both groups (p<0.001). Mean OCRs at 4, 7, 10, 13, 16 and $19^{\circ}C$ were 1386.0, 1601.7, 1741.0, 1799.2, 2239.1 and $2520.3mg\;O_2\;kg\;fish^{-1}\;h^{-1}$ in fry groups, and 83.8, 111.4, 126.3, 147.1, 187.7 and $221.3mg\;O_2\;kg\;fish^{-1}\;h^{-1}$ in fingerling groups, respectively. The OCRs decreased with increasing body weights at six different water temperatures (p<0.001). The relationship between water temperature and body weight is described by the following equation : OCR=1520.91+40.85T-49.22W ($r^2=0.95$, p<0.001). The energy loss by metabolic response increased with an increase in water temperature and a decrease in body weight (p<0.001). Mean energy loss rates by oxygen consumption at 4, 7, 10, 13, 16 and $19^{\circ}C$ were 907.9, 1046.5, 1141.6, 1177.0, 1467.3 and $1650.1kJ\;kg\;fish^{-1}\;d^{-1}$ in fry groups and 54.8, 73.0, 82.9, 96.2, 122.9 and $144.6kJ\;kg\;fish^{-1}\;d^{-1}$ in fingerling groups, respectively. The $Q_{10}$ values of fingerling groups were higher than those of fry groups at given temperature ranges. The $Q_{10}$ values at $4{\sim}7^{\circ}C$, $7{\sim}10^{\circ}C$, $10{\sim}13^{\circ}C$, $13{\sim}16^{\circ}C$ and $16{\sim}19^{\circ}C$ were 1.62, 1.32, 1.12, 2.07 and 1.48 in fry groups, and 2.59, 1.52, 1.67, 2.25 and 1.73 in fingerling groups, respectively.

Chocolate consumption and the prevalence of metabolic syndrome in the Korean adult population: an analysis based on the 2014-2016 Korea National Health and Nutrition Examination Survey

  • Kim, NaRae;Jeon, Min-Sun
    • Nutrition Research and Practice
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    • v.15 no.1
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    • pp.80-94
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    • 2021
  • BACKGROUND/OBJECTIVES: Recent studies have reported chocolate consumption has beneficial effects on blood pressure, obesity, and dyslipidemia, which are components of metabolic syndrome (MetS). However, evidence regarding these relationships in Asia is limited. The aim of this study was to investigate relations between chocolate consumption and MetS in Korea. SUBJECTS/METHODS: Study subjects were 6,982 adults aged 19-64 years free of major chronic diseases that participated in the 2014-2016 Korea National Health and Nutrition Examination Survey. Information on chocolate consumption was obtained using food frequency questionnaires. For primary analysis, subjects were divided into two groups: non-consumer (n = 3,741, 53.6%); consumer (n = 3,241, 46.4%). In order to investigate dose-response effects on MetS, chocolate consumers were divided into quartiles based on amounts consumed: Q1 (n = 789, 24.3%); Q2 (n = 837, 25.8%); Q3 (n = 863, 26.6%); Q4 (n = 752, 23.2%) in second analysis. RESULTS: Chocolate consumers; 1) were more physically active(P < 0.0001); 2) less likely to smoke(P < 0.0001); 3) paid more attention to food nutrition labels (P < 0.0001), and 4) had healthier dietary patterns, that is, they consumed vegetables, fruits, and dairy products more frequently(P < 0.0001) than non-consumers. Furthermore, chocolate consumers had a 30% lower risk of MetS (odds ratio, 0.70; 95% confidence interval, 0.58-0.86; P = 0.0005). However, dose-response effects between chocolate intake and MetS was not found by secondary analysis after excluding non-consumers. CONCLUSIONS: In conclusion, chocolate consumers had healthier lifestyles and dietary patterns and a lower prevalence of MetS than non-consumers, as determined by our primary analysis. Although dose-response effects were not found to be significant among chocolate consumers during secondary analysis, the patterns were partially similar. This cross-sectional finding shows chocolate consumption does not increase the risk of MetS. The prospective studies and intervention trials in Korea are needed to confirm this cross-sectional finding.

Application of array comparative genomic hybridization in Korean children under 6 years old with global developmental delay

  • Lee, Kyung Yeon;Shin, Eunsim
    • Clinical and Experimental Pediatrics
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    • v.60 no.9
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    • pp.282-289
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    • 2017
  • Purpose: Recent advancements in molecular techniques have greatly contributed to the discovery of genetic causes of unexplained developmental delay. Here, we describe the results of array comparative genomic hybridization (CGH) and the clinical features of 27 patients with global developmental delay. Methods: We included 27 children who fulfilled the following criteria: Korean children under 6 years with global developmental delay; children who had at least one or more physical or neurological problem other than global developmental delay; and patients in whom both array CGH and G-banded karyotyping tests were performed. Results: Fifteen male and 12 female patients with a mean age of $29.3{\pm}17.6months$ were included. The most common physical and neurological abnormalities were facial dysmorphism (n=16), epilepsy (n=7), and hypotonia (n=7). Pathogenic copy number variation results were observed in 4 patients (14.8%): 18.73 Mb dup(2)(p24.2p25.3) and 1.62 Mb del(20p13) (patient 1); 22.31 Mb dup(2) (p22.3p25.1) and 4.01 Mb dup(2)(p21p22.1) (patient 2); 12.08 Mb del(4)(q22.1q24) (patient 3); and 1.19 Mb del(1)(q21.1) (patient 4). One patient (3.7%) displayed a variant of uncertain significance. Four patients (14.8%) displayed discordance between G-banded karyotyping and array CGH results. Among patients with normal array CGH results, 4 (16%) revealed brain anomalies such as schizencephaly and hydranencephaly. One patient was diagnosed with Rett syndrome and one with $M{\ddot{o}}bius$ syndrome. Conclusion: As chromosomal microarray can elucidate the cause of previously unexplained developmental delay, it should be considered as a first-tier cytogenetic diagnostic test for children with unexplained developmental delay.

The protective effect of coenzyme Q10 on cytotoxicity of regin monomer of odontoblast caused by TEGDMA (코엔자임 Q10 처리에 따른 TEGDMA에 의해 유발된 치아 세포 사멸 억제 효과)

  • Lee, Ahreum;Park, Soyeong;Lee, Kyung Hee
    • Journal of Korean society of Dental Hygiene
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    • v.14 no.5
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    • pp.775-781
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    • 2014
  • Objectives : The purpose of the study is to investigate the protective effect of coenzyme $Q_{10}$ on cytotoxicity effect of dental monomers in odontoblast(MDPC-23). Methods : MDPC-23 was incubated with the(co)monomers triethylene glycol dimethacrylate (TEGDMA) with and without addition of coenzyme $Q_{10}$. The cell proliferation and survival was determined using WST-1 assay. The level of reactive oxygen species(ROS) was measured by immunofluorescent staining for DCF-DA. Results : TEGDMA treatment decreased the cell proliferation by dose dependently(0.1, 1, 2.5, 5, 10 mM) on the growth of MDPC-23 cells. Coenzyme $Q_{10}$ showed cell proliferation from 5 to $500{\mu}M$ by WST-1 assay. Pre-treatment coenzyme $Q_{10}$ showed the antioxidant effect on proliferation and viability of MDPC-23 after 48h(p<0.05). The positive cells were observed in non-coenyme $Q_{10}$ treatment group(group 2) in comparison with coenyme $Q_{10}$ pre-treatment group(group 1) by DCF-DA. The fluorescence positive cells showed 14.715(group 1) and 19.788(group 2) using image J system. Conclusions : TEGDMA induced cytotoxicity. The MDPC-23 cell death was associated with the increasing ROS. Coenyme $Q_{10}$ showed the antioxidant effects by decreasing ROS. This effects may contribute to the treatment of periodontal disease induced by TEGDMA after operation.

Identification of unbalanced complex chromosomal rearrangements in IVF-derived embryos during NGS analysis of preimplantation genetic testing: A case report

  • Yu, Eun Jeong;Kim, Min Jee;Park, Eun A;Hong, Ye Seul;Park, Sun Ok;Park, Sang-Hee;Lee, Yu Bin;Yoon, Tae Ki;Kang, Inn Soo
    • Journal of Genetic Medicine
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    • v.19 no.1
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    • pp.14-21
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    • 2022
  • Complex chromosome rearrangements (CCRs) are structural chromosomal rearrangements involving at least three chromosomes and more than two breakpoints. CCR carriers are generally phenotypically normal but related to higher risk of recurrent miscarriage and having abnormal offspring with congenital anomalies. However, most of CCR carriers are not aware of their condition until genetic analysis of either abortus or affected baby or parental karyotyping is performed. Herein, we present the case that CCR carrier patients can be identified by preimplantation genetic testing of preimplantation embryos. An infertile male patient with severe oligoasthenoteratozoospermia was diagnosed balanced reciprocal translocation, 46,XY,t(3;11) (p26;p14) at first. After attempting the first preimplantation genetic testing for structural rearrangement (PGT-SR) cycle, we found the recurrent segmental gain or loss on 21q21.3-q22.3 of five out of nine embryos. As a result of karyotype re-analysis, the patient's karyotype showed a balanced CCR involving chromosomes 3, 11, and 21 with three breakpoints 3p26, 11p14, and 21q21. The patient underwent two PGT-SR cycles, and a pregnancy was established after the transfer of an euploid embryo in the second cycle. Amniocentesis confirmed that the baby carried normal karyotype without mosaicism. At 37 weeks gestation, a healthy girl weighting 3,050 g was born.

Preliminary Study on Chlorination Reaction of Lithium Carbonate for Carbon-Anode-Based Oxide Reduction Applications

  • Jeon, Min Ku;Kim, Sung-Wook;Choi, Eun-Young
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.19 no.2
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    • pp.225-231
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    • 2021
  • The reaction between Li2CO3 and Cl2 was investigated to verify its occurrence during a carbon-anode-based oxide reduction (OR) process. The reaction temperature was identified as a key factor that determines the reaction rate and maximum conversion ratio. It was found that the reaction should be conducted at or above 500℃ to convert more than 90% of the Li2CO3 to LiCl. Experiments conducted at various total flow rate (Q) / initial sample weight (Wi) ratios revealed that the reaction rate was controlled by the Cl2 mass transfer under the experimental conditions adopted in this work. A linear increase in the progress of reaction with an increase in Cl2 partial pressure (pCl2) was observed in the pCl2 region of 2.03-10.1 kPa for a constant Q of 100 mL·min-1 and Wi of 1.00 g. The results of this study indicate that the reaction between Li2CO3 and Cl2 is fast at 650℃ and the reaction is feasible during the OR process.

Pattern Analysis of Personalized ECG Signal by Q, R, S Peak Variability (Q, R, S 피크 변화에 따른 개인별 ECG 신호의 패턴 분석)

  • Cho, Ik-Sung;Kwon, Hyeog-Soong;Kim, Joo-Man;Kim, Seon-Jong;Kim, Byoung-Chul
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.1
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    • pp.192-200
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    • 2015
  • Several algorithms have been developed to classify arrhythmia which rely on specific ECG(Electrocardiogram) database. Nevertheless personalized difference of ECG signal exist, performance degradation occurs because of carrying out diagnosis by general classification rule. Most methods require accurate detection of P-QRS-T point, higher computational cost and larger processing time. But it is difficult to detect the P and T wave signal because of person's individual difference. Therefore it is necessary to classify the pattern by analyzing personalized ECG signal and extracting minimal feature. Thus, QRS pattern Analysis of personalized ECG Signal by Q, R, S peak variability is presented in this paper. For this purpose, we detected R wave through the preprocessing method and extract eight feature by amplitude and phase variability. Also, we classified nine pattern in realtime through peak and morphology variability. PVC, PAC, Normal, LBBB, RBBB, Paced beat arrhythmia is evaluated by using 43 record of MIT-BIH arrhythmia database. The achieved scores indicate the average of 93.72% in QRS pattern detection classification.