• Title/Summary/Keyword: 1p/19q

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A Study on the Recognition Types of Adolescents' HMR (청소년의 HMR에 대한 인식 유형 연구)

  • Kwon, Hyuk-In;Cho, Yong-Hyen;Kim, Dong-Soo
    • The Journal of the Korea Contents Association
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    • v.19 no.6
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    • pp.441-449
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    • 2019
  • The purpose of this study was to find out the general type of consumer perception by defining and structuring consumers' self - awareness through the Q methodological approach to the types of youth perceived by HMR. This study focuses on the recognition of HMR as a major customer of HMR, and aims to provide information that can be considered in the HMR market by identifying consumption characteristics of youth consumers in the HMR market. To do this, the respondent classifies the statement card and analyzes the Q-sort. Q-sort, which is obtained by selecting and constructing the Q-population, Q factor analysis. (N = 10): price seeking type], the second type is [(N = 10)] which pursues the purchase by trust, (N = 2): seeking convenience], and the fourth type [(N = 3): seeking the appearance of the packaging)] Each type has its own characteristics. Each subjective opinion detected through this analysis is utilized as a basis for the follow-up study of HMR and will be provided as a marketing data of the HMR market in a future research direction.

TGF-β1 Protein Expression in Non-Small Cell Lung Cancers is Correlated with Prognosis

  • Huang, Ai-Li;Liu, Shu-Guang;Qi, Wen-Juan;Zhao, Yun-Fei;Li, Yu-Mei;Lei, Bin;Sheng, Wen-Jie;Shen, Hong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8143-8147
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    • 2014
  • To investigate the expression intensity and prognostic significance of TGF-${\beta}1$ protein in non-small cell lung cancer (NSCLC), immunohistochemistry was carried out in 194 cases of NSCLC and 24 cases of normal lung tissues by SP methods. The PU (positive unit) value was used to assess the TGF-${\beta}1$ protein expression in systematically selected fields under the microscope with Leica Q500MC image analysis. We found that the TGF-${\beta}1$ PU value was nearly two-fold higher in NSCLC than in normal lung tissues (p=0.000), being associated with TNM stages (p=0.000) and lymph node metastases (p=0.000), but not to patient age, gender, smoking history, tumor differentiation, histological subtype and tumor location (P>0.05). Univariate analysis indicated that patients with high TGF-${\beta}1$ protein expression and lymph node metastases demonstrated a poor prognosis (both p=0.000,). Multivariate analysis showed that TGF-${\beta}1$ protein expression (RR = 2.565, p=0.002) and lymph node metastases (RR=1.874, p=0.030) were also independent prognostic factors. Thus, TGF-${\beta}1$ protein expression may be correlated to oncogenesis and serve as an independent prognostic biomarker for NSCLC.

Polymorphisms of SLC22A9 (hOAT7) in Korean Females with Osteoporosis

  • Ahn, Seong Kyu;Suh, Chang Kook;Cha, Seok Ho
    • The Korean Journal of Physiology and Pharmacology
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    • v.19 no.4
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    • pp.319-325
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    • 2015
  • Among solute carrier proteins, the organic anion transporters (OATs) play an important role for the elimination or reabsorption of endogenous and exogenous negatively charged anionic compounds. Among OATs, SLC22A9 (hOAT7) transports estrone sulfate with high affinity. The net decrease of estrogen, especially in post-menopausal women induces rapid bone loss. The present study was performed to search the SNP within exon regions of SLC22A9 in Korean females with osteoporosis. Fifty healthy controls and 50 osteoporosis patients were screened for the genetic polymorphism in the coding region of SLC22A9 using GC-clamped PCR and denaturing gradient gel electrophoresis (DGGE). Six SNPs were found on the SLC22A9 gene from Korean women with/without osteoporosis. The SNPs were located as follows: two SNPs in the osteoporosis group (A645G and T1277C), three SNPs in the control group (G1449T, C1467T and C1487T) and one SNP in both the osteoporosis and control groups (G767A). The G767A, T1277C and C1487T SNPs result in an amino acid substitution, from synonymous vs nonsynonymous substitution arginine to glutamine (R256Q), phenylalanine to serine (F426S) and proline to leucine (P496L), respectively. The Km values and Vmax of the wild type, R256Q, P496L and F426S were 8.84, 8.87, 9.83 and $12.74{\mu}M$, and 1.97, 1.96, 2.06 and 1.55 pmol/oocyte/h, respectively. The present study demonstrates that the SLC22A9 variant F426S is causing inter-individual variation that is leading to the differences in transport of the steroid sulfate conjugate (estrone sulfate) and, therefore this could be used as a marker for certain disease including osteoporosis.

Early Alterations of Chlorophyll Fluorescence by Light-Chilling in Cucumber (Cucumis sativus) Leaves and Their Usage as Stress Indicators (오이 잎에서 저온 광저해에 의한 형광유도과정의 초기 변이와 스트레스 지표)

  • Ha, Suk-Bong;Young-Jae Eu;Choon-Hwan Lee
    • The Korean Journal of Ecology
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    • v.19 no.2
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    • pp.151-163
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    • 1996
  • To investigate the early symptoms of light-chilling, alterations of chlorophyll fluorescence transients were monitored in cucumber (Cucumis sativus L. cv. Ilmichungjang) leaves. During 24 h chilling, decreases in (Fv)m/Fm, qE and qQ, and an increase in Fo were observed. The chilling effects were not recovered at room temperature, and a significant increase in Fo was observed during the recovery period. After 6 h chilling, ‘dip’(D) level of the transients became obscure, and the negative slope after ‘peak’(P) disappeared. The first derivative (dFv/dt) of the fast fluorescence rise curve was used to obtain more accurate information about the changes in the transients. The maximal rate of the fluorescence increase in the D-p rise curve (Fr) has been the most frequently used chilling stress indicator. However, a correct value of Fr could not be measured when the D level became obscure. This problem was overcome by introducing a new indicator, HFr (dFv/dt at Fv = 1/2 (Fv)m), and HFr gave very similar values to Fr. To monitor the changes in curvature around D level, another new parameter, ${\Delta}S$(D-Fr), was also introduced. These three parameters decreased very sensitively during light-chilling. In addition, increases in these parameters were observed during the first 2 h chilling, but this increase in Fr was also observed in pea leaf discs dark-chilled for 15 min, suggesting that this very early change is a common response to chilling in both pea and cucumber leaves. Quenching coefficients were also very sensitive to chilling, especially qE. Discussion on the usage of these parameters as chilling stress indicators is given in the text.

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Prediction of Covid-19 confirmed number of cases using ARIMA model (ARIMA모형을 이용한 코로나19 확진자수 예측)

  • Kim, Jae-Ho;Kim, Jang-Young
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.12
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    • pp.1756-1761
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    • 2021
  • Although the COVID-19 outbreak that occurred in Wuhan, Hubei around December 2019, seemed to be gradually decreasing, it was gradually increasing as of November 2020 and June 2021, and estimated confirmed cases were 192 million worldwide and approximately 184 thousand in South Korea. The Central Disaster and Safety Countermeasures Headquarters have been taking strong countermeasures by implementing level 4 social distancing. However, as the highly infectious COVID-19 variants, such as Delta mutation, have been on the rise, the number of daily confirmed cases in Korea has increased to 1,800. Therefore, the number of cumulative confirmed COVID-19 cases is predicted using ARIMA algorithms to emphasize the severity of COVID-19. In the process, differences are used to remove trends and seasonality, and p, d, and q values are determined and forecasted in ARIMA using MA, AR, autocorrelation functions, and partial autocorrelation functions. Finally, forecast and actual values are compared to evaluate how well it was forecasted.

Enhanced Biofuel Production from High-Concentration Bioethanol Wastewater by a Newly Isolated Heterotrophic Microalga, Chlorella vulgaris LAM-Q

  • Xie, Tonghui;Liu, Jing;Du, Kaifeng;Liang, Bin;Zhang, Yongkui
    • Journal of Microbiology and Biotechnology
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    • v.23 no.10
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    • pp.1460-1471
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    • 2013
  • Microalgal biofuel production from wastewater has economic and environmental advantages. This article investigates the lipid production from high chemical oxygen demand (COD) bioethanol wastewater without dilution or additional nutrients, using a newly isolated heterotrophic microalga, Chlorella vulgaris LAM-Q. To enhance lipid accumulation, the combined effects of important operational parameters were studied via response surface methodology. The optimal conditions were found to be temperature of $22.8^{\circ}C$, initial pH of 6.7, and inoculum density of $1.2{\times}10^8cells/ml$. Under these conditions, the lipid productivity reached 195.96 mg/l/d, which was markedly higher than previously reported values in similar systems. According to the fatty acid composition, the obtained lipids were suitable feedstock for biodiesel production. Meanwhile, 61.40% of COD, 51.24% of total nitrogen, and 58.76% of total phosphorus were removed from the bioethanol wastewater during microalgal growth. In addition, 19.17% of the energy contained in the wastewater was transferred to the microalgal biomass in the fermentation process. These findings suggest that C. vulgaris LAM-Q can efficiently produce lipids from high-concentration bioethanol wastewater, and simultaneously performs wastewater treatment.

Piezoelectric Properties of Lead Free (Na1K1Cd)NbO3 Ceramics ((Na1K1Cd)NbO3 무연 세라믹스의 압전특성)

  • No Young-Woo;Yoo Young-Bae;Son Se-Mo;Chung Su-Tae
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.19 no.8
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    • pp.717-723
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    • 2006
  • Lead free $(Na_{0.5}K_{0.47}Cd_x)NbO_3$ ceramics (x=0.015-0.005) were prepared by the conventional mixed oxide route. The effects of CdO addition on the sintering, dielectric and piezoelectric properties of the samples were examined. The addition of CdO greatly enhanced the sinterability of ceramics and the sample has a lower dielectric loss. The $k_p\;and\;Q_m$ of the samples with 0.02 mol CdO addition are 0.35 and 125, respectively, The $(Na,K)NbO_3$ ceramics show a large degradation of $k_p$ due to the deliquescence when exposed to humidity, while the $(Na,K,Cd)NbO_3$ ceramics have no a significant degradation of it.

Infinite Families of Congruences for Partition Functions ${\bar{\mathfrak{EO}}}$(n) and ${\mathfrak{EO}}_e$(n)

  • Riyajur Rahman;Nipen Saikia
    • Kyungpook Mathematical Journal
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    • v.63 no.2
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    • pp.155-166
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    • 2023
  • In 2018, Andrews introduced the partition functions ${\mathfrak{EO}}$(n) and ${\bar{\mathfrak{EO}}}$(n). The first of these denotes the number of partitions of n in which every even part is less than each odd part, and the second counts the number of partitions enumerated by the first in which only the largest even part appears an odd number of times. In 2021, Pore and Fathima introduced a new partition function ${\mathfrak{EO}}_e$(n) which counts the number of partitions of n which are enumerated by ${\bar{\mathfrak{EO}}}$(n) together with the partitions enumerated by ${\bar{\mathfrak{EO}}}$(n) where all parts are odd and the number of parts is even. They also proved some particular congruences for ${\bar{\mathfrak{EO}}}$(n) and ${\mathfrak{EO}}_e$(n). In this paper, we establish infinitely many families of congruences modulo 2, 4, 5 and 8 for ${\bar{\mathfrak{EO}}}$(n) and modulo 4 for ${\mathfrak{EO}}_e$(n). For example, if p ≥ 5 is a prime with Legendre symbol $({\frac{-3}{p}})=-1$, then for all integers n ≥ 0 and α ≥ 0, we have ${\bar{\mathfrak{EO}}}(8{\cdot}p^{2{\alpha}+1}(pn+j)+{\frac{19{\cdot}p^{2{\alpha}+2}-1}{3}}){\equiv}0$ (mod 8); 1 ≤ j ≤ (p - 1).

The Research of Comparison Evaluation on the Decline in Artifact Using Respiratory Gating System in PET-CT (PET-CT 검사 시 호흡동조 시스템을 이용한 인공물 감소에 대한 비교 평가)

  • Kim, Jin-Young;Lee, Seung Jae;jung, Suk;Park, Min-Soo;Kang, Chun-Goo;Im, Han-Sang;Kim, Jae-Sam
    • The Korean Journal of Nuclear Medicine Technology
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    • v.19 no.2
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    • pp.63-67
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    • 2015
  • Purpose Among various causes that influence image quality degradation, various methods for decrease in Artifact occurred by respiration of patients are being used. Among them, this study intended to evaluate CTAC Shift correction method and additional scan compare to the Scan(Q static scan) using respiratory gated system. Materials and Methods This study was conducted on 10 patients, and used PET-CT Discovery 710 (GE Healthcare, MI, USA) and Varian's RPM system. 5.18 Mbq per kg of $^{18}F$-FDG was injected on patients, asked them to take a rest for 1 hour in the bed, and conducted test after urination. Images were visualized through Q static scan, CTAC Shift correction method, Additional scan based on the Whole body scan(WBS) with Artifact. Decrease in Artifact was compared in each image, conducted Gross Evalution, and measured changes of SUVmax. Results For image obtained through the CTAC Shift correction method through WBS with Artifact, 12~56%, Q static scan image showed 17~54% of change rate and Additional Scan showed -27~46% of change rate. In Blind Test, the CTAC Shift correction image showed the highest point with 4 points, Q static scan image showed 3.5 points, and Additional scan image showed 3.4 points. The standardized WBS scan through Oneway ANOVA and three types of Scan method showed significant difference(p<0.05), and did not show significant difference between the three Scan methods(p>0.05). However, the three Scan methods showed significant difference in Blind test. Conclusion Additional scan and Q static scan require more time than the CTAC Shift correction method, there is concern about excessive exposure to patients by CT rescan and Q static scan is difficult to apply on patients with inconsistent respiration or irregular respiration cycle due to pain. For CTAC Shift correction method, limited correction is possible and the range is limited as well. It is considered as a useful method of improving diagnostic value when hospitals use the system appropriately and develop various advantageous factors of each method.

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Study of the high pressure hose assemblies by accelerated life test (고압호스 조립체의 가속수명시험에 관한 연구)

  • Lee, Gi Chun;Lee, Yong Bum
    • Journal of Advanced Marine Engineering and Technology
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    • v.37 no.8
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    • pp.886-892
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    • 2013
  • Hydraulic hose assemblies are used as piping components for construction machinery, automobile, aircraft, industrial machinery, machine tools, and machinery for ships. Then the reliability of hose assemblies is important because total hydraulic system, which used to deliver the fluid power ($P^*Q$) needed to flexibility in the piping system, is not operated if the hose assembly failed in the system. The data of the accelerated life test estimated through the shape parameter(${\beta}$) resulting of the Weibull distribution analysis. This study has tried to reduce the test time resulting from varying impulse pressure range and the flexing diameter. Accelerated life test model for the test results was adopted the GLL(generalized log linear) and the accelerated indexes are identified as 6.64 for the pressure and 4.46 for flexing radius. Also, it found that shape parameter is 6.19, scale parameter(${\eta}$) is $1.035{\times}108$, which were adopted the pressure 35 MPa and the flexing diameter R100 mm in the used condition.