• Title/Summary/Keyword: 13D02

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Bladder And Rectum Dose Define 3D Treatment Planning for Cervix Cancer Brachtherapy Comparison of Dose-Volume Histograms for Organ Contour and Organ Wall Contour (자궁경부암의 고선량률 근접치료시 장기묘사 방법에 따른 직장과 방광의 선량비교 분석)

  • Kim, Jong-Won;Kim, Dae-Hyun;Choi, Joon-Yong;Won, Yeong-Jin
    • Journal of radiological science and technology
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    • v.35 no.4
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    • pp.327-333
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    • 2012
  • Purpose: To analyze the correlation between dose volume histograms(DVH) based on organ outer wall contour and organ wall delineation for bladder and rectum, and to compare the doses to these organs with the absorbed doses at the bladder and rectum. Material and methods: Individual CT based brachytherapy treatment planning was performed in 13 patients with cervical cancer as part of a prospective comparative trial. The external contours and the organ walls were delineated for the bladder and rectum in order to compute the corresponding dose volume histograms. The minimum dose in 0.1 $cm^3$, 1 $cm^3$, 2 $cm^3$, 5 $cm^3$, 10 $cm^3$ volumes receiving the highest dose were compared with the absorbed dose at the rectum and bladder reference point. Results: The bladder and rectal doses derived from organ outer wall contour and computed for volumes of 2 $cm^3$, provided a good estimate for the doses computed for the organ wall contour only. This correspondence was no longer true when large volumes were considered. Conclusion: For clinical applications, when volumes smaller than 5 $cm^2$ are considered, the dose-volume histograms computed from external organ contours for the bladder and rectum can be used instead of dose -volume histograms computed for the organ walls only. External organ contours are indeed easier to obtain. The dose at the ICRU rectum reference point provides a good estimate of the rectal dose computed for volumes smaller than 2 $cm^2$ only for a midline position of the rectum. The ICRU bladder reference point provides a good estimate of the dose computed for the bladder wall only in cases of appropriate balloon position.

A Study on the Relationships of Discomfort, Self-Esteem, Personality and Life-Satisfaction in Persons With Rheumatoid Arthritis (류마티스양 관절염환자의 불편감, 자기존중감, 성격 및 삶의 만족도간의 관계)

  • 김명자;송경애
    • Journal of Korean Academy of Nursing
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    • v.20 no.2
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    • pp.185-194
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    • 1990
  • The purpose of this study was to investigate the correlation of discomfort. self - esteem. personality and life - satisfaction in persons with rheumatoid arthritis and to provide basic data to help them attain a better quality of life. From Jan. 27 to Feb. 24, 1988, 53 patients, registered at a rheumatic clinic at one general hospital in Seoul, were accepted as subjects for this study. The instruments used for this study were a discomfort scale and life- satisfaction scale developed by the researcher, Rosenberg's Self - esteem Scale and Wallston and Wallston's Multidimensional Health Locus of Control (MEILC) Scale. The reliability of the scales were tested by Cronsbach's alpha. The collected data were analyzed by the SAS program using unpaired t-test, ANOVA, and Pearson's Correlation Coefficients. The results were as follows : 1. There was a significant difference in the subjects perceived discomfort level(t=-3.49, p= .0010) between the onset of the disease(14.87$\pm$9.02) and the present(19.87$\pm$8.44). 2. There was a significant correlation between the MHLC - internal score and the MHLC -chance score (r=-.4366, p= .0011). 3. The findings related to the demographic variables regarding the MHLC scores were as follows : 1) Regarding sex, there was a significant difference for the MHLC -internal score(t=4.2572, df=15.2, p= .0007) between male(32.13$\pm$2.47) and female(27.56$\pm$4.17). But the MHLC-chance score for male(15.13$\pm$2.85) was lower(t=3.1539, df=21.8, p$\pm$ .0047) than for female(19.47$\pm$6.29). 2) Regarding educational background, the MHLC - chance score for the below - high school group(20.52$\pm$5.81) was higher(t=2.5450, df=51.0, p= .0140) than the college graduate group(16.41$\pm$5.76). 4. The average Self - esteem score was 26.87 (S.D.=5.29) and there was a significant correlation between the Self- esteem score and the MHLC - chance score (r= .3122, p= .0026). 5. It was found that the subjects' Discomfort score was correlated with the Self -esteem score(r=-.3788, p= .0051) and the Life - satisfaction score(r=-3570, p= .0087). It was also found that subjects' Self - esteem score was correlated with the Life-satisfaction score(r= .4474, p= .0008).

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Preparation of fermentation broth of Sparassis latifolia containing soluble β-glucan using four Lactobacillus species (수용성 β-glucan을 함유한 꽃송이버섯 발효액의 제조)

  • Jo, Han-Gyo;Choi, Moon-Hee;Shin, Hyun-Jae
    • Journal of Mushroom
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    • v.13 no.1
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    • pp.50-55
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    • 2015
  • Glucan has been shown to have a significant role in the activation of the immune system, including increased activity of macrophages and so on. Sparassis latifolia (formerly S. crispa) is an edible mushroom abundant in dietary fiber and widely known to contain high levels of ${\beta}$-glucan. In the present study, fermentation broths containing soluble ${\beta}$-glucan were prepared by fermentation with mushrooms with four Lactobacillus species (L. plantarum subsp. Plantarum, L. acidophilus, L. helveticus, and L. delbrueckii subsp. Bulgaricus). After culturing four Lactobacillus spp. in MRS broth, each Lactobacillus was inoculated into MRS broth containing S. latifolia powder 5% (w/v) at $37^{\circ}C$ in an anaerobic incubator for five days. It showed that the ${\beta}$-glucan contents were different in each fermentation sample. The suitable conditions for the preparation of mushroom fermentation broths were investigated and discussed.

Explicating Motivations & Attitudes Affecting the Persistent Intention to Adopt Binge-Watching (수용자의 몰아보기 이용동기와 지속적 이용의도에 영향을 미치는 영향 요인에 대한 연구)

  • Han, Sun Sang;Yu, Hongsik;Shin, Dong-Hee
    • The Journal of the Korea Contents Association
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    • v.17 no.2
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    • pp.521-534
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    • 2017
  • In 2013 the Netflix, an OTT in USA, launched all at once 13 episodes of the House of Cards season. Binge-watching is the word which means watching continuously 2~6 episodes of a TV program with one sitting, the new normal of TV watching behavior, cultural and social currents all over the world. This study has analyzed the factors and motivations which affect to the persistent intention to use binge-watching. It conducted an online survey from 333 Quota sample from Korean age groups between 20th~60th with 81 questionnaires. The 5 groups were induced as motivation factors to binge-watching. The 3 groups which consisted of , , are affecting as positive to intention to use binge-watching. But the other 2 groups which are and doing as negative. The survey has shown that the persistent intention to binge-watching is affected by ages more younger, whom doing binge watching more frequently, whom estimating more higher to the conceived usefulness to use. As a theoretical model, expanded technology acceptance model was adopted and US drama House of Cards. This study could promote the next generation contents planning and S-VOD service industry.

Spatial Distribution and Sampling Plan for Pink Citrus Rust Mite, Aculops pelekassi (Acari: Eriophyidae) in Citrus Orchard (감귤원에서 귤녹응애 공간분포 분석과 표본조사법 개발)

  • Song, Jeong-Heub;Hong, Soon-Yeong;Lee, Shin-Chan
    • Korean journal of applied entomology
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    • v.51 no.2
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    • pp.91-97
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    • 2012
  • The dispersion indices, spatial pattern and sampling plan for pink citrus rust mite (PCRM), Aculops pelekassi, monitoring was investigated. Dispersion indices of PCRM indicated the aggregated spatial pattern. Taylor's power law provided better description of variance-mean relationship than Iwao's patchiness regression. Fixed-precision levels (D) of a sequential sampling plan were developed using by Taylor's power law parameters generated from PCRM on fruit sample (cumulated number of PCRM in $cm^2$ of fruit). Based on Kono-Sugino's empirical binomial the mean density per $cm^2$ could be estimated from fruit ratio with more than 12 rust mites per $cm^2$: $ln(m)=4.61+1.23ln[-ln(1-p_{12})]$. To determine the optimal tally threshold, the variance (var(lnm)) for mean (lnm) in Kono-Sugino equation was estimated. The lower and narrow ranged change of variance for esimated mean showed at a tally threshold of 12. To estimate PCRM mean density per $cm^2$ at fixed precision level 0.25, the required sample number was 13 trees, 5 fruits per tree and 2 points per fruit (total 130 samples).

Processing Optimization and Physicochemical Characteristics of Collagen from Scales of Yellowfin Tuna (Thunnus albacares)

  • Han, Yuna;Ahn, Ju-Ryun;Woo, Jin-Wook;Jung, Cheol-Kyun;Cho, Sueng-Mock;Lee, Yang-Bong;Kim, Seon-Bong
    • Fisheries and Aquatic Sciences
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    • v.13 no.2
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    • pp.102-111
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    • 2010
  • This study was conducted to investigate the optimal conditions of collagen extraction from scales of yellowfin tuna (Thunnus albacares) using surface response methodology. Four independent variables of NaOH concentration and pretreatment fime in alkali pretreatment and enzyme concentration and treatment time in enzyme hydrolysis were used to predict a model equation for the collagen yield. The determinant coefficient ($R^2$) for the equation was 0.906. The values of the independent variables for the maximum yield were 0.32 N NaOH, 16.38 h alkali pretreatment time, 0.18% enzyme concentration, and 31.02 h enzyme treatment time. In the physicochemical properties of tuna scale collagen, sodium dodecyl sulfate-polyacrylamide gel electrophoresis of tuna scale collagen showed the same migration distances as that of calf skin collagen. The amide A, I, II, and III regions of tuna scale collagen in Fourier transform infrared measurements were shown in the peaks of 3,414 $cm^{-1}$, 1,645 $cm^{-1}$, 1,553 $cm^{-1}$, and 1,247 $cm^{-1}$, respectively. The amount of imino acids in tuna scale collagen was 18.97% and the collagen denaturation temperature was $33^{\circ}C$. The collagen solubility as a function of NaCl concentration decreased to 4% NaCl (w/v) and the collagen solubility as a function of pH was high at pH 2-4 and sharply decreased from pH 4 to pH 7. Viscosity of the collagen solution decreased continuously until $30^{\circ}C$ and this decreasing rate slowed in the temperature range of $35-50^{\circ}C$.

A clinical pilot study of jawbone mineral density measured by the newly developed dual-energy cone-beam computed tomography method compared to calibrated multislice computed tomography

  • Kim, Hyun Jeong;Kim, Ji Eun;Choo, Jiyeon;Min, Jeonghee;Chang, Sungho;Lee, Sang Chul;Pyun, Woong Beom;Seo, Kwang-Suk;Karm, Myong-Hwan;Koo, Ki-Tae;Rhyu, In-Chul;Myoung, Hoon;Heo, Min-Suk
    • Imaging Science in Dentistry
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    • v.49 no.4
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    • pp.295-299
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    • 2019
  • Purpose: This clinical pilot study was performed to determine the effectiveness of dual-energy cone-beam computed tomography (DE-CBCT) in measuring bone mineral density (BMD). Materials and Methods: The BMD values obtained using DE-CBCT were compared to those obtained using calibrated multislice computed tomography (MSCT). After BMD calibration with specially designed phantoms, both DE-CBCT and MSCT scanning were performed in 15 adult dental patients. Three-dimensional (3D) Digital Imaging and Communications in Medicine data were imported into a dental software program, and the defined regions of interest (ROIs) on the 3-dimensional surface-rendered images were identified. The automatically-measured BMD values of the ROIs (g/㎤), the differences in the measured BMD values of the matched ROIs obtained by DE-CBCT and MSCT 3D images, and the correlation between the BMD values obtained by the 2 devices were statistically analyzed. Results: The mean BMD values of the ROIs for the 15 patients as assessed using DE-CBCT and MSCT were 1.09±0.07 g/㎤ and 1.13±0.08 g/㎤, respectively. The mean of the differences between the BMD values of the matched ROIs as assessed using DE-CBCT and calibrated MSCT images was 0.04±0.02 g/㎤. The Pearson correlation coefficient between the BMD values of DE-CBCT and MSCT images was 0.982 (r=0.982, P<0.001). Conclusion: The newly developed DE-CBCT technique could be used to measure jaw BMD in dentistry and may soon replace MSCT, which is expensive and requires special facilities.

Analysis of Impacts of Digital-Textbooks on Learners' Self-regulated Learning and Problem-solving Competency (디지털교과서가 학습자의 자기조절학습 및 문제해결 역량에 미치는 효과 분석)

  • Cha, Hyun-Jin;Kye, Bokyung;Jeong, Kwang Hoon
    • The Journal of the Korea Contents Association
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    • v.17 no.2
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    • pp.13-25
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    • 2017
  • This study aims to analyze the impacts on self-regulated learning (SRL) and problem-solving (PS) competencies rather than learning achievement through the use of digital textbooks in the SMART learning environment. To achieve the objective, $3^{rd}$ and $4^{th}$ grade elementary and $1^{st}$ year middle school students were selected from 29 schools where the digital textbooks were utilized in the subjects of science in pilot schools in 2014. In this, One-Group Pretest-Posttest Designs were applied as a research method to analyze SRL and PS competencies. Additionally, the effect size of Cohen's d was presented in order to display the practical significance. The results showed the positive impacts on SRL and PS competencies, in spite of a small effect size of about 0.2 through the use of digital textbooks. ANCOVA was conducted to determine the difference in the impacts according to demographic variables. The results demonstrated that the difference in the impacts on both SRL and PS were statistically significant according to the grade and level. For SRL, both the elementary grade 4 and middle school students showed more significant differences than elementary grade 3. Moreover, for PS, the elementary grade 4 students showed the most significant difference.

Effects of Lactobacillus reuteri-based Direct-fed Microbial Supplementation for Growing-Finishing Pigs

  • Shon, K.S.;Hong, J.W.;Kwon, O.S.;Min, B.J.;Lee, W.B.;Kim, I.H.;Park, Y.H.;Lee, I.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.3
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    • pp.370-374
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    • 2005
  • Two experiments were conducted to evaluate the effects of direct-fed microbial supplementation on the growth performance and nutrient digestibility in pigs. In experiment 1, forty eight pigs were used in a 42-d growth assay. There were four pigs per pen and three pens per treatment. Dietary treatments included 1) NC (without antibiotic basal diet), 2) PC (NC diet+0.1% antibiotic, 100 g/kg chlortetracycline), 3) DFM-1 (NC diet+0.2% Lactobacillus reuteri and Lactobacillus salivarius complex) and 4) DFM-2 (NC diet+0.2% Lactobacillus reuteri, Lactobacillus salivarius, Lactobacillus plantarum and Yeast complex). For the overall period, no treatment had significant effects in growth performance. In the nutrition digestibility, the pigs fed DFM diets were improved in DM and N digestibility compared with the pigs fed NC and PC diets but it was not significantly different. In experiment 2, sixty four crossbred pigs were used in a 98-d growth assay. There were four pigs per pen and four pens per treatment. Dietary treatments included 1) HND (high nutrient diet), 2) LND (low nutrient diet), 3) HND+DFM (HND diet+0.2% Lactobacillus reuteri and Lactobacillus plantarum complex) and 4) LND+DFM (LND diet+0.2% Lactobacillus reuteri and Lactobacillus plantarum complex). For overall period of growing phase, the pigs fed LND diets had improved gain/feed (p=0.01) and for overall period in the finishing phase, the pigs fed LND with DFM diets had higher ADG, ADFI and gain/feed than the others but there were no significant differences (p>0.13). In total period of growing-finishing phase, the pigs fed LND diet had higher gain/feed than the pigs fed HND diets (p<0.05). In growing phase, there were not significant differences among the treatments means for DM and N digestibility. However, the pigs fed diets with DFM had improved N digestibility (p<0.02) compared to the pigs fed diets without DFM in finishing phase. In conclusion, DFM slightly improved the growth performance in growing-finishing pigs.

Estimation of Genetic Parameters for Direct, Maternal and Grandmatemal Genetic Effects for Birth, Weaning and Six Month Weights of Hanwoo (Korean Cattle)

  • Choi, S.B.;Lee, J.W.;Kim, N.S.;Na, S.H.;Keown, J.F.;Van Vleck, L.D.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.2
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    • pp.149-154
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    • 2000
  • The objectives of this study of Hanwoo (Korean Cattle) were 1) to estimate genetic parameters for direct and maternal genetic effects for birth weight, weaning weight, and six months weight which can be used for genetic evaluations and 2) to compare models with and without grandmatemal effects. Data were obtained from the National Livestock Research Institute in Rural Development Administration (RDA) of Korea and were used to estimate genetic parameters for birth weight (BW, n=10,889), weaning weight at 120-d (WW, n=8,637), and six month weight (W6, n=8,478) in Hanwoo. Total number of animals in pedigrees was 14,949. A single-trait animal model was initially used to obtain starting values for multiple-trait animal models. Estimates of genetic parameters were obtained with MTDFREML using animal models and derivative-free REML (Boldman et al., 1995). Estimates of direct heritability for BW, WW, and W6 analyzed as single-traits were 0.09, 0.03, and 0.02 from Model 3 which included direct and maternal genetic, maternal permanental environmental effects, and effects due to sire ${\times}$ region ${\times}$ year-season interaction, respectively. Ignoring sire ${\times}$ region ${\times}$ year-season interaction effect in the model (Model 2) resulted in larger estimates for direct heritability than for Model 3. Estimates of maternal heritability for BW, WW and W6 were 0.04, 0.05, and 0.07 from Model 3, respectively. The estimates of direct-maternal genetic correlation were positive for BW, WW, and W6 with Model 3 but were negative with Model 2 for WW and W6. Estimates of direct genetic correlations between BW and WW, BW and W6, and WW and W6 were large: 0.52, 0.45, and 0.90, respectively. Genetic correlations were also large and positive for maternal effects for BW with maternal effects for WW and W6 (0.69 and 0.74), and even larger for WW with W6 (0.97). The log likelihood values were the same for models including grandmatemal effects as for models including maternal effects for all traits. These results indicate that grandmatemal effects are not important for these traits for Hanwoo or that the data structure was not adequate for estimating parameters for a grandmatemal model.