• 제목/요약/키워드: 13D02

검색결과 317건 처리시간 0.036초

Nutrient Utilization, Body Composition and Lactation Performance of First Lactation Bali Cows (Bos sondaicus) on Grass-Legume Based Diets

  • Sukarini, I.A.M.;Sastradipradja, D.;Sutardi, T.;Mahardika, IG.;Budiarta, IG.A.
    • Asian-Australasian Journal of Animal Sciences
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    • 제13권12호
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    • pp.1681-1690
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    • 2000
  • A study on energy and protein utilization, and milk production of Bali cows on grass-legume diets was carried out using 12 first lactation cows (initial BW $263.79{\pm}21.66kg$) during a period of 16 weeks starting immediately post calving. The animals were randomly allotted into 4 dietary treatment groups R1, R2, R3 and R4, receiving from the last 2 months of pregnancy onwards, graded improved rations based on a mixture of locally available grass and legume feed ad libitum. R1 contained on a DM basis 70% elephant grass (PP, Penisetum purpureum) plus 30% Gliricidia sepia leaves (GS), R2 was 30% PP plus 55% GS supplemented with 15% Hibiscus tilliactus leaves (HT, defaunating effect), R3 and R4 were 22.5% PP+41.25% GS+11.25% HT+25% concentrate, where R3 was not and R4 supplemented with zinc di-acetate. TDN, CP and zinc contents of the diets were 58.2%, 12.05% and 18.3 mg/kg respectively for R1, 65.05%, 16.9% and 25.6 mg/kg respectively for R2, 66.03%, 16.71% and 29.02 mg/kg respectively for R3 and 66.03%, 16.71% and 60.47 mg/kg respectively for R4. Milk production and body weight were monitored throughout the experimental period. In vivo body composition by the urea space technique validated by the body density method and supported by carcass data was estimated at the start and termination of the experiment. Nutrient balance and rumen performance characteristics were measured during a balance trial of 7 days during the 3rd and 4th week of the lactation period. Results indicated that quality of ration caused improvement of ruminal total VFA concentration, increments being 52 to 65% for R2, R3 and R4 above R1, with increments of acetate being less (31 to 48%) and propionate being proportionally more in comparison to total VFA increments. Similarly, ammonia concentrations increased to 5.24 to 7.07 mM, equivalent to 7.34 to 9.90 mg $NH_3-N/100ml$ rumen fluid. Results also indicated that feed quality did not affect DE and ME intakes, and heat production (HP), but increased GE, UE, energy in milk and total retained energy (RE total) in body tissues and milk. Intake-, digestible- and catabolized-protein, and retained-protein in body tissues and milk (Rprot) were all elevated increasing the quality of ration. Similar results were obtained for milk yield and components with mean values reaching 2.085 kg/d (R4) versus 0.92 kg/d (R1) for milk yield, and 170.22 g/d (R4) vs 71.69 g/d (R1), 105.74 g/d (R4) vs 45.35 g/d (R1), 101.34 g/d (R4) vs 46.36 g/d (R1) for milk-fat, -protein, and -lactose, respectively. Relatively high yields of milk production was maintained longer for R4 as compared to the other treatment groups. There were no significant effects on body mass and components due to lactation. From the relationship $RE_{total}$ (MJ/d)=12.79-0.373 ME (MJ/d); (r=0.73), it was found that $ME_{m}=0.53MJ/kgW^{0.75}.d$. Requirement of energy to support the production of milk, ranging from 0.5 to 3.0 kg/d, follows the equation: Milk Prod. ($Q_{mp}$, kg/d)=[-2.48+4.31 ME($MJ/kg^{0.75}.d$)]; (r=0.6) or $Q_{mp}$=-3.4+[0.08($ME-RE_{body\;tissue}$)]MJ/d]; (r=0.94). The requirement for protein intake for maintenance ($IP_m$) equals $6.19 g/kg^{0.75}.d$ derived from the relationship RP=-47.4+0.12 IP; (r=0.74, n=9). Equation for protein requirement for lactation is $Q_{nl}$=[($Q_{mp}$)(% protein in milk)($I_{mp}$)]/100, where $Q_{nl}$ is g protein required for lactation, $Q_{mp}$ is daily milk yield, Bali cow's milk-protein content av. 5.04%, and $I_{mp}$ is metabolic increment for milk production ($ME_{lakt}/ME_{m}=1.46$).

인삼부산물 급여에 따른 비육돈의 생산성 및 육질 특성에 미치는 영향 (Effects of Dietary Ginseng By-product on Growth Performance and Pork Quality Parameters in Finishing Pigs)

  • 박준철;김영화;정현정;지상윤;이성대;유재원;장해동;문홍길;김인철
    • Journal of Animal Science and Technology
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    • 제49권6호
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    • pp.839-846
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    • 2007
  • 본 시험은 인삼부산물 급여 유무에 따른 돼지 생산성, 혈액, 도체 및 육질 특성에 관하여 조사하였다. 시험 동물은 2원 교잡종(LandraceYorkshire) 육성-비육돈 24두를 공시하였으며 개시 체중은 65.81±2.02kg이였다. 기초 사료를 대조구(CON)로 설정하였고, 처리구(GBP)은 인삼 부산물을 기초사료의 lupin 2.5%로 대체하였다. 시험구는 완전임의 배치법으로 암·수 동일한 비율로 각 처리구당 4마리씩 3반복 실시하였다. 생산성에서 일당사료섭취량은 GBP가 CON 보다 유의적으로 낮았다(P<0.0001). 혈장의 생화학적 조성에서는 total protein, blood urea nitrogen, glucose, albumin, calcium 그리고 inorganic phosphate는 각각 GBP가 CON 보다 유의적으로 높은 함량을 나타내었다. 도체 및 육질 특성은 GBP 및 CON간에 유의적인 차이가 나타나지 않았다. 돈육의 총 ginsenoside 함량은 GBP가 CON 보다 유의적으로 높은 함량을 나타내었고 TBRAs는 저장 6일과 13일에 GBP가 CON 보다 유의적으로 낮았다. 이상의 시험 결과를 종합하면, 인삼부산물 급여는 혈장의 화학적 조성의 변화를 가져왔고, 돈육의 ginsenoside의 함량을 증가시키고 지방산패도를 감소시켰는데 이 사실은 인삼부산물이 돼지의 사료첨가제로 이용될 수 있는 가능성을 나타낸다.

한방제재 첨가급여가 한우송아지의 성장, 혈액성상 및 설사에 미치는 영향 (Effects of Supplementing Herbs on Growth Performances, Blood Composition and Diarrhea in Hanwoo Calves)

  • 김병기;최창본;이상욱;백경훈;정대진;황은경
    • Journal of Animal Science and Technology
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    • 제53권5호
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    • pp.451-459
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    • 2011
  • 생후 2개월령 한우송아지를 각 처리구별로 8두씩 배치하여 총 24두(3처리${\times}$ 8두)를 대상으로 대조구(한방제재 무첨가)와 T1구 (한방제재 0.3% 첨가), T2구(한방제재 0.5% 첨가구)로 나누어 배치하여 총 150일간 시험한 결과는 다음과 같다. 총 증체량과 두당 총 사료섭취량은 T1구가 각각 142.8 kg와 545.9 kg으로 다른 처리구보다 크게 높게 나타나 통계적인 유의차가 있었다(p<0.05). 혈액의 이화학적 성상에서 평균적으로 총 콜레스테롤 함량은 86.43~97.00 mg/dl 범위에 있었으며, TG는 13.26~13.86 mg/dl, GOT는 76.97~79.60 mg/dl, GPT는 19.54~20.97 mg/dl, WBC는 8.75~9.95 k/${\mu}{\ell}$, RBC는 10.14~11.91 M/${\mu}{\ell}$, 헤모글로빈은 10.74~11.20 g/$d{\ell}$로서 처리구간에 유의적인 차이는 없었다. 그러나 면역글로블린(IgG)은 시험구(6.05~6.02 mg/ml)가 대조구(5.74 mg/ml) 보다 높았고(p<0.05), 시험 월령이 경과함에 따라 점차 낮아지는 경향이었다. 시험기간 동안의 송아지 분변 조사에서, 시험개시후 시험 1~2개월령에 발병원인균의 수가 가장 많았으나, 시험이 경과함에 따라 낮아지는 경향이었고, 분변중의 기생충(Eimeria spp), 용혈성 대장균(E. Coli)와 바이러스(BVDV)는 대조구가 시험구보다 높은 경향을 보였고, 시험기간 동안의 설사 발병두수에서도 시험2구가 대조구보다 감소하는 경향이었으나 통계적인 유의차는 없었다(대조구 24두 ; T1구 9두 ; T2구 13두). 이상의 결과를 종합해보면, 한방제재 첨가는 송아지의 성장률 및 송아지설사 예방에 영향을 미치는 것으로 판단된다.

Effects of Expander Operating Conditions on Nutrient Digestibility in Finishing Pigs

  • S.L., Traylor;K.C., Behnke;J.D., Hancock;R.H., Hines;S.L., Johnston;B.J., Chae;In K., Han
    • Asian-Australasian Journal of Animal Sciences
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    • 제12권3호
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    • pp.400-410
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    • 1999
  • Five experiments were conducted using finishing pigs (PIC L326 sires $\times$ C15 dams) to examine the effects of expander operating conditions on nutrient digestibility in finishing pigs. The effects of different expanding conditions (0, 11.7, 24.4, $32.5kg/cm^2$) for corn-SBM based diets (Exp. 1), wheat meddlings diet (Exp. 2), sorghum-SBM based diets (Exp. 3) and wheat-SBM based diet (Exp. 4). Exp. 5 was conducted as a $2{\times}4$ factorial arrangement and factors examined were 2 soy products (raw soybean and SBM) and 4 expanding conditions (0, 14.1, 28.1, $42.2kg/cm^2$). In experiment 1, total production rates (p>0.10) were similar among treatments. The amount of fines decreased (cubic effect, p<0.001) as cone pressure was increased from 0 to $11.7kg/cm^2$, with smaller differences as cone pressure was further increased to $35.2kg/cm^2$. Nutrient digestibilities increased (p<0.02) as the feed was subjected to higher cone pressures. Digestibilities of DM, N, and GE were maximized at $24.4kg/cm^2$ cone pressure. The DE of the diet expanded at 24.4 and $35.2kg/cm^2$ increased by 172 and 109 kcal/kg, respectively, compared to the diet processed at $0kg/cm^2$ cone pressure. In experiment 2, total production and screened pellets production rates were similar among the processing treatments (p>0.21). The amount of fines decreased (quadratic effect, p<0.03) by 9 kg/h as cone pressure was increased from 0 to $11.7kg/cm^2$. Digestibilities of DM (p<0.02), N (p<0.001), and GE (p<0.002) were increased as cone pressure was increased from 0 to $35.2kg/cm^2$. DM, N, and GE digestibility in the pigs fed the midds-based diet increased by 8, 13, and 10%, respectively, at the highest processing cone pressure compared to the diets without any cone pressure. In experiment 3, the conditioned mash moistures for the treatments were numerically similar around 15% moisture. As the expander cone pressure was increased from 0 to $11.7kg/cm^2$, energy consumption for the pellet mill decreased (quadratic effect, p<0.004) from 14.1 to 12.0 kWh/t. Dry matter and gross energy digestibility increased (cubic effects, p<0.006) as cone pressure was increased from 0 to $35.2kg/cm^2$ with the largest improvement occurring as cone pressure was increased from 0 to $11.7kg/cm^2$. Nitrogen digestibility increased (cubic effect, p<0.001) from 78.3 to 81.0% as the feed was subjected to the higher cone pressures, with N digestibility being maximized at $24.4kg/cm^2$ cone pressure. The DE of the diet increased (cubic effect, p<0.001) by 225 kcal/kg as cone pressure was increased from 0 to $11.7kg/cm^2$. In experiment 4, pellet moisture decreased and moisture loss increased as cone pressure was increased from 0 to $35.2kg/cm^2$. Also, starch gelatinization of the wheat-based diets increased from 16.8 to 49.1% as the diets were processed at 0 and $35.2kg/cm^2$ cone pressure. Nutrient digestibilities were not affected (p>0.18) by any increase in cone pressure. In experiment 5, pellet moisture decreased as cone pressure was increased 0 to $35.2kg/cm^2$. The amount of moisture loss for the diets expanded at $42.2kg/cm^2$ was 3.0 and 3.8% for the SBM and raw soybean (RB) diets, respectively. Starch gelatinization for the SBM diets were 19% greater than the RB diets. The RB diets had lower DM, N and GE digestibilities as compared to the SBM diets. The DE of the RB diets were lower (p<0.02) than the SBM diets. DM (p<0.06), N (p<0.02), and GE (p<0.001) digestibilities of the dietary treatments increased as cone pressure was increased 0 to $42.2kg/cm^2$.

수확시기 및 원료 조건에 따른 풋귤 식초의 항산화 활성 (Antioxidant activity of premature mandarin vinegar according to harvest period and raw material conditions)

  • 박보연;최재원;김성현;윤예랑;이영란;이영미;정지혜
    • 한국식품과학회지
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    • 제52권4호
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    • pp.333-341
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    • 2020
  • 항산화 활성이 우수한 풋귤 식초를 개발하기 위하여 풋귤의 수확 시기(7월-9월)에 따른 총 페놀 및 플라보노이드 함량 및 항산화 활성을 측정하고, 3가지 원료 조건(풋귤 분쇄액, 10% 건조 청피 첨가 풋귤 분쇄액, 10% 로스팅 청피 첨가 풋귤 분쇄액)으로 제조된 풋귤 식초의 발효 특성, 항산화 성분 및 항산화 활성을 비교하였다. 7월에 수확된 풋귤 착즙액은 1.02±0.02 ㎍ GAE/mL의 가장 높은 총 페놀 함량이 확인되었으며, 플라보노이드 함량은 수확시기에 따른 유의적인 차이가 존재하지 않았다. 항산화 활성은 7월-8월에 수확된 풋귤 착즙액이 9월에 수확된 풋귤 착즙액보다 유의적으로 높은 DPPH 라디칼 소거능 및 환원력을 나타내었으며, 이러한 결과를 바탕으로 7월에 수확된 풋귤 착즙액을 식초 원료로 선정하였다. 원료 조건을 달리하여 제조된 식초의 최종 산도는 풋귤 식초가 6.0%, 건조 청피 첨가 풋귤 식초가 6.3%, 로스팅 청피 첨가 풋귤 식초가 6.7%로 모두 85%의 높은 발효 효율을 보였다. 건조 또는 로스팅 청피가 첨가된 풋귤 식초는 발효 13일차에 5% 산도에 도달하였으며, 풋귤 식초보다 발효 기간이 단축되고 높은 산 생성능을 나타내었다. 원료조건에 따라 색도의 변화가 확인되었지만 유의적인 차이는 없었다. 유기산 함량은 건조 청피가 첨가된 풋귤 식초가 acetic acid를 비롯한 총 유기산 함량이 30,201 mg/L으로 가장 높았으며, 특히 풋귤 식초보다 1.4배 높았다. 총 페놀 함량은 로스팅 청피 첨가 풋귤 식초에서 0.62±0.02 ㎍ GAE/mL으로 풋귤 식초와 약 2배 이상의 차이를 보였으나, 총 플라보노이드 함량은 풋귤 식초가 3.00±0.15 ㎍ CE/mL로 가장 높았다. DPPH 라디칼 소거능의 EC50 값은 건조 및 로스팅 청피 첨가 풋귤 식초가 각각 5.83±1.66 nL/mL, 4.71±0.07 nL/mL으로 풋귤 식초(9.16±0.87 nL/mL)보다 유의적으로 높은 활성을 나타냈으며, 환원력에서는 로스팅 청피 첨가 풋귤 식초가 7.47±0.28 nL/mL으로 활성이 가장 높았다. 이상의 결과로부터 7월에 생산된 풋귤 착즙액을 원료로 로스팅 청피를 첨가한 풋귤 식초는 초산 발효가 우수하고 높은 유기산 및 페놀 함량으로 우수한 항산화 활성을 나타내어 기존 풋귤 식초보다 항산화능이 강화된 기능성 식초로 활용될 수 있을 것으로 사료된다.

Genetic analysis of milk production traits of Tunisian Holsteins using random regression test-day model with Legendre polynomials

  • Zaabza, Hafedh Ben;Gara, Abderrahmen Ben;Rekik, Boulbaba
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권5호
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    • pp.636-642
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    • 2018
  • Objective: The objective of this study was to estimate genetic parameters of milk, fat, and protein yields within and across lactations in Tunisian Holsteins using a random regression test-day (TD) model. Methods: A random regression multiple trait multiple lactation TD model was used to estimate genetic parameters in the Tunisian dairy cattle population. Data were TD yields of milk, fat, and protein from the first three lactations. Random regressions were modeled with third-order Legendre polynomials for the additive genetic, and permanent environment effects. Heritabilities, and genetic correlations were estimated by Bayesian techniques using the Gibbs sampler. Results: All variance components tended to be high in the beginning and the end of lactations. Additive genetic variances for milk, fat, and protein yields were the lowest and were the least variable compared to permanent variances. Heritability values tended to increase with parity. Estimates of heritabilities for 305-d yield-traits were low to moderate, 0.14 to 0.2, 0.12 to 0.17, and 0.13 to 0.18 for milk, fat, and protein yields, respectively. Within-parity, genetic correlations among traits were up to 0.74. Genetic correlations among lactations for the yield traits were relatively high and ranged from $0.78{\pm}0.01$ to $0.82{\pm}0.03$, between the first and second parities, from $0.73{\pm}0.03$ to $0.8{\pm}0.04$ between the first and third parities, and from $0.82{\pm}0.02$ to $0.84{\pm}0.04$ between the second and third parities. Conclusion: These results are comparable to previously reported estimates on the same population, indicating that the adoption of a random regression TD model as the official genetic evaluation for production traits in Tunisia, as developed by most Interbull countries, is possible in the Tunisian Holsteins.

간호대학생의 결핵에 대한 지식 및 태도가 결핵감염 예방행위에 미치는 영향 (The Effect of Knowledge, Attitudes and Prevention Behaviors for Tuberculosis Infection in Nursing Students)

  • 임승주;이현주
    • Journal of Korean Biological Nursing Science
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    • 제18권1호
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    • pp.43-50
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    • 2016
  • Purpose: This study aimed to identify the relationship among knowledge, attitudes and prevention behaviors (PB) on tuberculosis (Tb) infection in nursing students. Methods: 268 subjects were recruited from two universities located in C D cities of Korea and data were collected utilizing self-reported questionnaires. Results: The mean scores of knowledge, attitudes and PB on Tb infection were 64.83, 3.18 and 2.97. The knowledge differed according to gender (t=-3.16, p=.002), grades (F=32.19, p<.001), educational experience about Tb (EETb) (F=10.59, p<.001), learning information about Tb (t=3.08, p=.002) and getting Tb: self or others (t=2.78, p=.006). The attitudes differed according to grades (F=7.71, p<.001) and EETb (F=2.68, p=.047). The PB differed according to grades (F=7.02, p<.001) and EETb (F=4.55, p=.004). Significant correlations were found between knowledge and PB (r=.20, p=001), attitudes and PB (r=.33, p<.001). The most significant factor influencing PB was attitudes with R2 value of 13.9% (F=11.81, p<.001). Conclusion: These findings indicate that knowledge and attitude adjustment may be necessary to improve PB for Tb infection in nursing students. Moreover further study is necessary to find out the ways to reinforce the level of attitudes. The results of the study can be utilized in educational programs for preventing Tb infection in nursing students.

고양이 치수에서 교감신경에 의한 미세순환조절에 관한 기능적 연구 (ROLE OF SYMPATHETIC NERVE ON THE CONTROL OF MICROCIRCULATION IN THE FELINE DENTAL PULP)

  • 김성교
    • Restorative Dentistry and Endodontics
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    • 제21권1호
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    • pp.375-384
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    • 1996
  • The purpose of this study was to investigate the functional involvement of sympathetic nerve in the control of the microcirculation in the dental pulp with the aim of elucidation of the involvement of neuropeptides and sympathetic nerve in neurogenic inflammation. Experiments were done on the 7 cats anesthetised with sodium pentobarbital, and sympathetic nerve to the' dental pulp was stimulated electrically (10 Hz, 4 V, 1.5 ms, 3.5 mins). Ana-adrenoceptor antagonist phentolamine and a neuropeptide Y antagonist D-myo-inositol-1,2,6-trisphosphate (PP56) were injected close intra-arterially into the dental pulp without changing the systemic blood pressure. The probe of laser Doppler flowmeter was placed on the buccal surface of ipsilateral canine teeth to the stimulation, and pulpal blood flow was measured. Stimulation of the sympathetic nerve decreased pulpal blood flow by $55.24{\pm}7.74\;%$ (mean${\pm}$SEM, n = 13). Stimulation of the sympathetic nerve following the injection of the ${\alpha}$-adrenoceptor antagonist phentolamine ($0.1{\mu}g$/kg) caused decrease of pulpal blood flow by $14.35{\pm}3.43%$ (mean${\pm}$SEM, n=5). Phentolamine attenuated the sympathetic nerve-induced pulpal blood flow decrease by $74.02{\pm}9.32%$ (mean${\pm}$SEM) Stimulation of the sympathetic nerve following the injection of the neuropeptide Y antagonist PP56 (2.3 mg/kg) caused decrease of pulpal blood flow by $30.64{\pm}7.92%$ (mean${\pm}$SEM, n=6). PP56 attenuated the sympathetic nerve-induced pulpal blood flow decrease by $44.37{\pm}11.01%$ (mean${\pm}$SEM). These data provide evidences of the co-contribution of nerepinephrine and neuropeptide Y on the sympathetic nerve-induced vasoconstriction in the feline dental pulp. In addition, they show functional evidences that sympathetic nerve plays an active role in controlling the microcirculation of the dental pulp.

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Electrophysiological Characterization of AMPA and NMDA Receptors in Rat Dorsal Striatum

  • Jeun, Seung-Hyun;Cho, Hyeong-Seok;Kim, Ki-Jung;Li, Qing-Zhong;Sung, Ki-Wug
    • The Korean Journal of Physiology and Pharmacology
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    • 제13권3호
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    • pp.209-214
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    • 2009
  • The striatum receives glutamatergic afferents from the cortex and thalamus, and these synaptic transmissions are mediated by ${\alpha}$-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) and N-methyl D-aspartate (NMDA) receptors. The purpose of this study was to characterize glutamate receptors by analyzing NMDA/AMPA ratio and rectification of AMPA and NMDA excitatory postsynaptic currents (EPSCs) using a whole-cell voltage-clamp method in the dorsal striatum. Receptor antagonists were used to isolate receptor or subunit specific EPSC, such as (DL)-2-amino-5-phosphonovaleric acid (APV), an NMDA receptor antagonist, ifenprodil, an NR2B antagonist, CNQX, an AMPA receptor antagonist and IEM-1460, a GluR2-lacking AMPA receptor blocker. AMPA and NMDA EPSCs were recorded at - 70 and + 40 mV, respectively. Rectification index was calculated by current ratio of EPSCs between + 50 and - 50 mV. NMDA/AMPA ratio was 0.20${\pm}$0.05, AMPA receptor ratio of GluR2-lacking/GluR2-containing subunit was 0.26${\pm}$0.05 and NMDA receptor ratio of NR2B/NR2A subunit was 0.32${\pm}$0.03. The rectification index (control 2.39${\pm}$0.27) was decreased in the presence of both APV and combination of APV and IEM-1460 (1.02${\pm}$0.11 and 0.93${\pm}$0.09, respectively). These results suggest that the major components of the striatal glutamate receptors are GluR2-containing AMPA receptors and NR2A-containing NMDA receptors. Our results may provide useful information for corticostriatal synaptic transmission and plasticity studies.

NF-κB Activation and PPAR Transactivational Effects of a New Aliphatic Acid Amide from Pericarps of Zanthoxylum piperitum

  • Yang, Seo Young;Tai, Bui Huu;Song, Seok Bean;Li, Wei;Yan, Xi Tao;Sun, Ya Nan;Nguyen, Phuong Thao;Kim, Young Ho
    • Bulletin of the Korean Chemical Society
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    • 제35권8호
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    • pp.2361-2366
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    • 2014
  • A new aliphatic acid amide, ZP-amide F (1), and eight known compounds, including bungeanumamide A (2), tumuramide C (3), ZP-amide A (4), ZP-amide B (5), ZP-amide D (6), hyperin (7), quercitrin (8), and (-)-sesamin (9), were isolated from pericarps of Zanthoxylum piperitum. The effects of these compounds on $TNF{\alpha}$-induced NF-${\kappa}B$ activation and transactivational activity of PPARs, including $PPAR{\alpha}$, $PPAR{\beta}({\delta})$ and $PPAR{\gamma}$ subtypes, were evaluated. Compounds 7 and 9 exhibited potent inhibitory effects on $TNF{\alpha}$-induced NF-${\kappa}B$ activation with $IC_{50}$ values of 5.50 and $8.10{\mu}M$, respectively. Aliphatic acid amide compounds 3, 4 and 6 displayed enhanced effects on PPAR transactivational activity with $EC_{50}$ values of 47.12, 19.13 and $12.02{\mu}M$, respectively. Among them, compound 4 demonstrated an increase in $PPAR{\alpha}$ transactivational activity, compound 3 showed a moderate increase on all PPAR subtypes, whereas compound 6 displayed weak PPAR transactivational activity.