• 한국발생생물학회지:발생과생식
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• 제18권3호
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• pp.133-137
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• 2014

Rearing experiments were conducted using several regimes combined with different photoperiods and water temperatures to investigate the role of temperature and photoperiod as environmental cues regulating reproduction in red marbled rockfish, Sebastiscus tertius. The initial gonadosomatic index (GSI) was $1.62{\pm}0.32%$ and that in the $15^{\circ}C$ control was $7.01{\pm}0.46%$ at the end of the experiment. The highest GSI was $9.10{\pm}0.35%$ in the 12L:12D photoperiod-treated fish. The highest GSI at $19^{\circ}C$ was $15.03{\pm}0.86%$ in the 12L:12D photoperiod treatment. The initial hepatosomatic index (HSI) was $3.09{\pm}0.72%$ and that in the $15^{\circ}C$ control was $3.88{\pm}0.45%$. The highest HSI was $4.00{\pm}0.56%$ in the 15L:9D treated fish. The highest HSI at $19^{\circ}C$ was $4.05{\pm}0.63%$ in the 12L:12D treated fish.

• Journal of Information Processing Systems
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• 제12권2호
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• pp.249-262
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• 2016

In 2004, Yang et al. proposed a threshold proxy signature scheme that efficiently reduced the computational complexity of previous schemes. In 2009, Hu and Zhang presented some security leakages of Yang's scheme and proposed an improvement to eliminate the security leakages that had been pointed out. In this paper, we will point out that both Yang and Hu's schemes still have some security weaknesses, which cannot resist warrant attacks where an adversary can forge valid proxy signatures by changing the warrant $m_w$. We also propose two secure improvements for these schemes.

• 한국해안해양공학회:학술대회논문집
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• 한국해안해양공학회 1993년도 정기학술강연회 발표논문 초록집
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• pp.106-109
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• 1993

1990년 9월 12일 오전 03시 50분, 9월의 홍수로 인해 한강 하류의 둑인 일산제가 수압을 견디지 못하고 파괴되었다. 이로인해 고양 의 70％가 침수되었으며 인명피해 및 막대한 재산피해가 발생하였다. 본 연구는 동수역학적 원리에 근거한 2차원 범람모형을 수립하여. 일차적으로 일출제 붕괴 당시의 시간에 따른 치수양상 및 치수면적, 침수고를 재현하여 당시의 범람 양상과 비교해보고 추후 개선된 모델링과 범람가능지의 지형자료 입력화를 통해 한강변의 범람시 정확한 예보로서 피해를 경감하는데 그 궁극적 목적이 있다. (중략)

• Nonlinear Functional Analysis and Applications
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• 제27권3호
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• pp.649-662
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• 2022

This paper is concerned with the existence of solutions for a class of 𝚽-Kirchhoff type equations with critical exponent in Orlicz-Sobolev spaces. Our technical approach is based on variational methods.

• Nonlinear Functional Analysis and Applications
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• 제28권3호
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• pp.775-791
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• 2023

In this manuscript, we prove the existence of the coupled coincidence point by using g-couplings in multiplicative metric spaces (MMS). Further we show that existence of a fixed point in ordered MMS having t-property. Finally, some examples and application are presented for attesting to the credibility of our results.

• 한국식품과학회지
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• 제19권3호
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• pp.188-194
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• 1987

건멸치 저장중 저장 온도 및 습도가 품질에 미치는 영향을 밝히기 위하여 건멸치를 12개월간 저장 하면서 주요 품질지표 성분의 변화를 조사하고 각 저장 조건별 7개월 저장후 상온 방치중 품질 변화를 조사 하였다. 건멸치의 단분자중 수분량은 $5^{\circ}C$에서 8.18%. $25^{\circ}C$에서 5.86%였다. 건멸치의 평형수분 함량은 저장온도가 낮고 상대습도가 높을수록 증가하고, 저장 온가 높고 상대 습도가 낮을수록 감소하는 경향이었다. $5^{\circ}C$및 $-3^{\circ}C$에 저장된 건멸치의 휘발성 염기질소 생성량은 저장고 내의 고습도의 영향으로 상온, $10^{\circ}C$ 및 $-18^{\circ}C$ 보다 많았다. 지질산화에 의한 갈변은 저장 온도가 높아 짐에 따라 증가 하였으나 $-3^{\circ}C$ 및 $-18^{\circ}C$에서는 큰유의 차없이 미미하게 증가 하였다. L값은 일반적으로 저장온도가 낮고 고상대습도 조건에서는 감소속도가 낮고 고상대습도 조건에서는 감소속도가 빨랐으나 a 및 b값은 저장 온도가 높아짐에 따라서 크게 증가하여 상온처리구는 $-18^{\circ}C$ 처리구 보나 각각 4.53 및 1.77배 증가 하였다. 종합적인 관능적 기호도를 보통정도 수준인 3.0을 기준으로 하여 저장 기간을 설정하면 상온저장시는 $4{\sim}6$개월. $10^{\circ}C$는 $5{\sim}8$개월 $5^{\circ}C$는 $8{\sim}10$개월 그리고 $-3^{\circ}C$ 이하에서는 12개월 저장 가능 하였다. 저장 7개월 된 건멸치를 5개월간 상온 저장시 $5^{\circ}C$ 및 $-18^{\circ}C$ 처리구는 기존 상온 저장에 비하여 휘발성 염기질소 함량은 1.03 및 1.38배, 지질 산화에 의한 갈변은 1.03 및 2.15배, a 및 b값은 $1.21{\sim}1.60$ 및 $1.02{\sim}2.80$배 각각 증가 하였다.

• 대한영상의학회지
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• 제81권5호
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• pp.1151-1163
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• 2020

목적 본 후향적 연구는 심장 CT를 이용하여 대동맥판막치환술 후 발생한 판누스(pannus)가 시간 경과에 따라 증가하는지를 평가하고 심초음파 결과와 비교하는 것을 목적으로 한다. 대상과 방법 2011년 4월부터 2017년 11월까지 CT에서 판누스가 발견되어 follow-up 심장 CT와 심초음파를 촬영한 17명의 환자를 포함하였다. 대동맥판막치환술 후 판누스 발견까지의 시간은 평균 10.5 ± 7.1년이었다. 처음 판누스가 발견된 CT와 이후 CT에서 판누스의 변화를 확인하고, 심초음파 결과의 변화를 paired t-test를 이용하여 분석하였다. 인공판막의 열리는 정도와 판누스의 크기는 Pearson 상관관계분석을 이용하여 평가하였다. 결과 판누스의 크기는 follow-up CT에서 증가하였다(p < 0.05). 대동맥판막을 지나는 최고 혈류속도(3.9 ± 0.8 m/s vs. 4.2 ± 0.8 m/s, p = 0.03)와 평균 압력차(36.4 ± 15.5 mm Hg vs. 42.1 ± 15.8 mm Hg, p = 0.03)는 심초음파상 의미 있게 증가하였다. 인공판막의 열리는 정도는 약간 감소하였으나 의미 있는 변화는 아니었다(73.1 ± 8.3° vs. 69.4 ± 12.1°, p = 0.12). 인공판막의 열리는 정도와 판누스의 크기는 음의 상관관계를 보였다(r = -0.57, p < 0.001). 결론 판누스는 시간이 지남에 따라 커졌고, 이에 따라 인공판막을 지나는 혈류속도와 평균 압력차가 증가하였다. 심장 CT는 판누스의 크기를 평가할 수 있고, 이는 혈역학적 변화와 관련이 있으며 추후 수술 여부 결정에 도움을 줄 수 있다.

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2003년도 제3회 국제심포지움 및 학술대회
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• pp.97-97
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• 2003

Embryonic stem (ES) cells, derived from preimplantation embryos, are able to differentiate into various types of cells consisting the whole body, or pluripotency. In addition to the plasticity, ES cells are expected to be different from terminally differentiated cells in very many ways, such as patterns of gene expressions, ability and response of the cells in confronting environmental stimulations, metabolism, and growth rate. As a model system to differentiate these two types of cells, human ES (hES, MB03) cells and terminally differentiated cells (HeLa), we examined the ability of these two types of cells in confronting a severe oxidative insult, that is $H_2 O_2$. Ratio of dying cells as determined by the relative amount of dye neutral red entrapped within the cells after the exposures. Cell death rates were not significantly different when either MB03 or HeLa were exposed up to 0.4 mM $H_2 O_2$. However, relative amount of dye entrapped within the cells sharply decreased down to 0.12% in HeLa cells when the cells were exposed to 0.8 mM $H_2 O_2$, while it was approximately 54% in MB03. Pretreatment of cells with BSO (GSH chelator) and measurement of GSH content results suggest that cellular GSH is the major defensive mechanism of hES cells. Induction of apoptosis in hES cell was confirmed by DNA laddering, induction of Bax, and chromatin condensation. In summary, hES cells 1) are extremely resistant to oxidative stress, 2) utilize GSH as a major defensive mechanism. and 3) experience apoptosis upon exposure to oxidative stress.

• 대한예방한의학회지
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• 제13권3호
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• pp.87-99
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• 2009

Objectives : The study was to examine the empirical evidence concerning the effects of massage intervention for the laboring women and to investigate the effect sizes related to the characteristics of intervention. Methods : Meta analysis was performed. A total of 11 trials related to massage intervention between 2000 and 2007 were reviewed. Results : Massage intervention showed a beneficial effect on length of labor(1st stage : U=46.75, p=0.00, 2nd stage : U=6.13, p=0.01), perception of childbirth experience(U=12.57, p=0.00), intensity of uterine contraction at the active(U=6.34, p=0.01) and the transition phases(U=24.83, p=0.00), and interval of uterine contraction at the active phase(U=4.83, p=0.03). Massage decreased systolic(U=10.81, p=0.00) and diastolic blood pressure at the transition phase(U=10.60, p=0.00). However, massage had no effect on subjective and objective labor pain and anxiety. No differences were found in effectiveness of massage according to characteristics of intervention(massage material, massager, and massage site) except for anxiety(QB=4.82, p=0.03) and diastolic blood pressure at the active phase by massage site(QB=4.52, p=0.03). Conclusions :We found that massage intervention for the laboring women had an empirical evidence on improving perception of childbirth experience and shortening length of labor. These results should be interpreted with caution due to the lack of studies. More full-scale randomized clinical trials with reliable designs are recommended to further warrant the effectiveness of massage.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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• pp.78-78
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• 2003

Embryonic stem (ES) cells, derived from preimplantation embryo, are able to differentiate into various types of cells consisting the whole body, or pluripotency. In contrast, terminally differentiated cells do not usually alter their nature but frequently die or transform if they are exposed to inappropriate external stimulations. In addition to the plasticity, ES cells are expected to be different from terminally differentiated cells in very many ways, such as patterns of gene expressions, ability and response of the cells in confronting environmental stimulations, metabolism, and growth rate. As a model system to differentiate these two types of cells, human ES cells (MB03) and terminally differentiated cells (HeLa), we examined the ability of these two types of cells in confronting a severe oxidative insult, that is $H_2O$$_2$. Approximately 1$\times$10$^4$ cells were plated in 96 well plate and serum starved for overnight. The conditioned cells were exposed to a various concentration of $H_2O$$_2$ fur 24 hrs and loaded with neutral red (50$\mu\textrm{g}$/ml) for 4 hrs, washed with PBS for 2 min three times, and entrapped dye was dissolved out using acetic ethanol. Cytotoxicity was determined by reading the amount of dye in the medium using microplate reader. equipped with 575 nm filter. Relative amount of the dye entrapped within MB03 or HeLa were not significantly different when cells were exposed up to 0.4 mM $H_2O$$_2$. However, this sharply decreased down to 0.12% in HeLa cells when the cells were exposed to 0.8 mM $H_2O$$_2$, while it was approximately 54% in MB03 suggesting that this concentration of $H_2O$$_2$ is the defensive threshold for HeLa cells. The resistance to oxidative stimulation reversed, however, when cells were co-treated with BSO (L-buthionine- 〔S, R〕-sulfoximine) which chelates intracellular GSH. This result suggests that cellular GSH is the major defensive mechanism of human ES cells. Induction of enzymes involved in GSH metabolism and type of cell death is currently being studied.