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Neolignan Derivatives from the Flower of Magnolia biondii Pamp. and their Effects on IL-2 expression in T-cells

  • Nguyen, Thi Tuyet Mai;Nguyen, Thi Thu;Lee, Hyun-Su;Jun, Chang-Duk;Min, Byung Sun;Kim, Jeong Ah
    • Natural Product Sciences
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    • v.23 no.2
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    • pp.119-124
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    • 2017
  • The isolation of the MeOH extract from the flower bud of Magnolia biondii Pamp. using various column chromatographies and HPLC led to eleven neoglignan derivatives (1 - 11). Their structures were mainly determined by 1D and 2D NMR spectral data analysis and physiological methods. The isolated compounds (1 - 11) were tested for anti-allergic effects using IL-2 inhibitory assay in Jurkat T cells.

SCREENING OF IN VITRO INHIBITORY EFFECTS OF 15 HERBAL MEDICINES ON CYP450 ISOFORMS

  • Shon, J.H.;Kim, M.J.;Park, J.Y.;Yoon, Y.R.;Chun, B.H.;Shin, J.G.
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.119-119
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    • 2001
  • Traditional herbal medicines(HM) are frequently taken in combination with conventional medications in Korea, but few reports have been addressed to herb-drug interaction. We assessed the inhibitory potential of 15 commonly used HMs in Korea on CYP450 isoforms.(omitted)

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Pure Red Cell Aplasia Associated with Good Syndrome

  • Okui, Masayuki;Yamamichi, Takashi;Asakawa, Ayaka;Harada, Masahiko;Horio, Hirotoshi
    • Journal of Chest Surgery
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    • v.50 no.2
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    • pp.119-122
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    • 2017
  • Pure red cell aplasia (PRCA) and hypogammaglobulinemia are paraneoplastic syndromes that are rarer than myasthenia gravis in patients with thymoma. Good syndrome coexisting with PRCA is an extremely rare pathology. We report the case of a 50-year-old man with thymoma and PRCA associated with Good syndrome who achieved complete PRCA remission after thymectomy and postoperative immunosuppressive therapy, and provide a review of the pertinent literature.