• 제목/요약/키워드: 10-Oxodaunomycinone

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새로운 10-옥소다우노마이시논 유도체의 합성 (Syntheses of Novel 10-Oxodaunomycinone Derivatives)

  • 노영쇠;김선자;조인호;신홍식
    • 약학회지
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    • 제43권1호
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    • pp.11-15
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    • 1999

  • A brief route for regiospecific synthesis of novel 10-Oxodaunomycinone Derivatives (10a, b) is described. Dimethoxy-l-tetralone 4 was converted to acetyl tetralone (5a, b) which was oxidized with oxygen to obtain cis-diol compound (8a, b). The construction of (10a, b) was completed by the condensation of phthaloyl dichloride 9 with cis-diol (8a, b)

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