• Title/Summary/Keyword: 10-MDP

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Miniaturized Chromatographic Quality Control of $^{99m}Tc$ Radiopharmaceuticals (Miniaturized Chromatography에 의한 $^{99m}Tc$-표지 방사성의약품의 정도 관리)

  • Yeom, Mi-Kyoung;Jeong, Jae-Min;Jin, Kwang-Ho;Cho, Kyu-Jin;Chung, June-Key;Lee, Myung-Chul;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.24 no.1
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    • pp.133-137
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    • 1990
  • The general use of a number of $^{99m}Tc-labelled$ compounds makes the need for good routine quality control procedures, especially the labelling efficiency measurements. The purpose of these study were to measure the labelling efficiency of $^{99m}Tc-labelled$ MDP, DTPA, Tin colloid, and Antimony sulfide colloid using miniaturized paper and instant thin layer chromatography. The chromatographic systems include whatman 3 MM paper and acetone, Gelman ITLC-SG and 0.9% sodium chloride. The chromatographic strips are miniaturized $(1\times10\;cm)$, marked and numbered. Labelling efficiencies of $^{99m}Tc-labelled$ DTPA and Tin colloid were above 98.0%. $^{99m}Tc-labelled$ Antimony sulfide colloid was 90.0%. And labelling efficiency of $^{99m}Tc-labelled$ MDP was 89.0% Coefficient variance of $^{99m}Tc-labelled$ MDP, DTPA, Tin colloid, and Antimony sulfide colloid were 5.14%, 2.06%, 1.82% and 4.90%, respectively. We found that this miniaturized chromatographic quality control was simple and reliable.

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Earthwork Planning via Reinforcement Learning with Heterogeneous Construction Equipment (강화학습을 이용한 이종 장비 토목 공정 계획)

  • Ji, Min-Gi;Park, Jun-Keon;Kim, Do-Hyeong;Jung, Yo-Han;Park, Jin-Kyoo;Moon, Il-Chul
    • Journal of the Korea Society for Simulation
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    • v.27 no.1
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    • pp.1-13
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    • 2018
  • Earthwork planning is one of the critical issues in a construction process management. For the construction process management, there are some different approaches such as optimizing construction with either mathematical methodologies or heuristics with simulations. This paper propose a simulated earthwork scenario and an optimal path for the simulation using a reinforcement learning. For reinforcement learning, we use two different Markov decision process, or MDP, formulations with interacting excavator agent and truck agent, sequenced learning, and independent learning. The simulation result shows that two different formulations can reach the optimal planning for a simulated earthwork scenario. This planning could be a basis for an automatic construction management.

Determination of Ship Collision Avoidance Path using Deep Deterministic Policy Gradient Algorithm (심층 결정론적 정책 경사법을 이용한 선박 충돌 회피 경로 결정)

  • Kim, Dong-Ham;Lee, Sung-Uk;Nam, Jong-Ho;Furukawa, Yoshitaka
    • Journal of the Society of Naval Architects of Korea
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    • v.56 no.1
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    • pp.58-65
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    • 2019
  • The stability, reliability and efficiency of a smart ship are important issues as the interest in an autonomous ship has recently been high. An automatic collision avoidance system is an essential function of an autonomous ship. This system detects the possibility of collision and automatically takes avoidance actions in consideration of economy and safety. In order to construct an automatic collision avoidance system using reinforcement learning, in this work, the sequential decision problem of ship collision is mathematically formulated through a Markov Decision Process (MDP). A reinforcement learning environment is constructed based on the ship maneuvering equations, and then the three key components (state, action, and reward) of MDP are defined. The state uses parameters of the relationship between own-ship and target-ship, the action is the vertical distance away from the target course, and the reward is defined as a function considering safety and economics. In order to solve the sequential decision problem, the Deep Deterministic Policy Gradient (DDPG) algorithm which can express continuous action space and search an optimal action policy is utilized. The collision avoidance system is then tested assuming the $90^{\circ}$intersection encounter situation and yields a satisfactory result.

Reinforcement Learning-based Dynamic Weapon Assignment to Multi-Caliber Long-Range Artillery Attacks (다종 장사정포 공격에 대한 강화학습 기반의 동적 무기할당)

  • Hyeonho Kim;Jung Hun Kim;Joohoe Kong;Ji Hoon Kyung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.45 no.4
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    • pp.42-52
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    • 2022
  • North Korea continues to upgrade and display its long-range rocket launchers to emphasize its military strength. Recently Republic of Korea kicked off the development of anti-artillery interception system similar to Israel's "Iron Dome", designed to protect against North Korea's arsenal of long-range rockets. The system may not work smoothly without the function assigning interceptors to incoming various-caliber artillery rockets. We view the assignment task as a dynamic weapon target assignment (DWTA) problem. DWTA is a multistage decision process in which decision in a stage affects decision processes and its results in the subsequent stages. We represent the DWTA problem as a Markov decision process (MDP). Distance from Seoul to North Korea's multiple rocket launchers positioned near the border, limits the processing time of the model solver within only a few second. It is impossible to compute the exact optimal solution within the allowed time interval due to the curse of dimensionality inherently in MDP model of practical DWTA problem. We apply two reinforcement-based algorithms to get the approximate solution of the MDP model within the time limit. To check the quality of the approximate solution, we adopt Shoot-Shoot-Look(SSL) policy as a baseline. Simulation results showed that both algorithms provide better solution than the solution from the baseline strategy.

MDP-Based Stepwise Network Reconfiguration Scheme for Dynamic WDM Network (동적 WDM네트워크를 위한 MDP기반의 단계적 망 재구성 기법)

  • Park, Byoung-Seob
    • The Journal of the Korea Contents Association
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    • v.8 no.1
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    • pp.160-168
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    • 2008
  • We completed a new cluster system based on WDM by proposing virtual topology reconfiguration schemes. The key idea of the proposed scheme Is to construct a set with the longest chains of requests of connecting nodes which need to be assigned a wavelength. All the sets have no common factor, that is, there is no duplicated link among the requests of connecting. After making the set satisfying this condition, we could assign a wavelength to per corresponding set. We could reconfigure a virtual topology with this scheme collectively. we compared our scheme to existing approaches by the OWns simulation tool. As the results, we gained improved performances, reducing 10% of blocking rate and improving 30% of ADM utilization in terms of the blocking probability and the ADM utilization.

Comparing of the Administered Activities and the Effective Dose of the Various Pediatric Dose Formulas of Nuclear Medicine (핵의학검사의 방사성의약품 소아투여량 공식 별 투여량 및 유효선량 비교)

  • Gil, Jong-Won
    • Journal of the Korea Convergence Society
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    • v.8 no.8
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    • pp.147-154
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    • 2017
  • The purpose of this study is to calculate and compare administered activities(MBq) and effective dose(mSv) of the various pediatric dose formulas of pediatric nuclear medicine and to provide base data for the criteria of the optimal administered activities. This study compares dosages and effective doses of 5 types of pediatric dose formulas(Clark rule, Area rule, Webster rule, Young rule, Solomon(Fried) rule) based on the dosage for adults of 2 types of radiopharmaceuticals($^{99m}Tc$-MDP, $^{99m}Tc$-Pertechnetate). The administered activities in adults, which is the criteria for calculating the Pediatric administered activities, used the value from the 'Nuclear Medicine' written by J-G Jeong & M-Ch Lee. and the administered activities by the radioactivity per effective dose(mSv/MBq) of the radiopharmaceuticals for calculating the effective dose used the value from ICRP 80 and the UNSCEAR 2008 Report. As a result of the study, the output of Young rule is the lowest, and its difference between other formulas is from minimum 1.7 times to maximum 3,4 times. The difference between administered activities of $^{99m}Tc$-MDP is maximum 309.9MBq and the effective dose is 3.76mSv. $^{99m}Tc$-Pertechnetate showed the figure at the maximum 154.9MBq and the effective dose has a difference of 5.50mSv. Since the pediatric dose formulas differ not only in administered activities but also in effective doses, the optimal administered activities have to be developed for optimization of medical radiation.

Experiment to Calculate the Dosage of Radiopharmaceutical Products during the Bone Scan Tests (Bone Scan 검사 시 실제 환자에게 투여되는 용량 계산을 위한 실험)

  • Lee, Wang-Hui;Ahn, Sung-Min
    • The Journal of the Korea Contents Association
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    • v.15 no.4
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    • pp.357-362
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    • 2015
  • In this experiment, we are to know the administered radioactivity in the actual patients by measuring the remained radioactivity when administering the isotope with noted MDP, the radiopharmaceutical product, to 50 visited patients for the bone scan, confirmed the radioactivity administered to actual patients. We confirmed the actual administered amount of remained radioactivity in the syringe and 3-way by using a gauger after administering the isotope with MDP noted via 3-way with 50 patients maintaining 3-way after CT or MRI among the visited patients for the bone scan in the department of nuclear medicine. As a result of radioactivity in the 3-way and syringe pre and post injection of radiopharmaceutical products in 50 patients, average radioactivity of pre-injection is 31.75 mCi, average remained radioactivity in the syringes after injection is 1.22 mCi, and the average remained radioactivity in 3-way after injection is 0.95 mCi. The average of actual administered radioactivity is 29.57, so it is obvious that average 2.18 mCi was administered for less than the dosage that we initially intended to inject. When determining the dosage in view of the radioactivity that remains in the 3-way with the syringe, it would be possible to accurately dose the desired dosage to be administered to actual patients.

Effects of different types of xanthophyll extracted from marigold on pigmentation of yellow-feathered chickens

  • Yu Wei;Kun Qin;Xu Qin;Fulong Song;Xiao Xu
    • Animal Bioscience
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    • v.36 no.12
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    • pp.1853-1859
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    • 2023
  • Objective: This study aimed to explore the effects of different types of xanthophyll extracted from marigold on the growth performance, skin color, and carcass pigmentation. Methods: A total of 192 healthy 60-day-old yellow-feathered broilers weighing an average of 1,279±81 g were randomly allocated to 4 groups, each with 6 replicates and 8 broilers. The 4 treatments were as follows: i) CON group, fed with basal diet; ii) LTN group, supplemented with lutein; iii) MDP group, supplemented with monohydroxyl pigment including dehydrated lutein, β-cryptoxanthin, and α-cryptoxanthin; iv) LTN+MDP group, supplemented with lutein and monohydroxyl pigment in proportion to 1:1. The supplementary content of LTN, MDP, and LTN+MDP was 2 g/kg. Skin color was measured after 7, 14, 21, and 28 days of feeding the dietary treatments. The breast, thigh, and abdominal fat of slaughtered chickens were stored in cold storage at 4℃ for 24 hours and then the meat color of lightness (L*), redness (a*), and yellowness (b*) values was determined. Results: The results showed that all treatments enhanced the yellow scores of subwing skin on day 14, 21, and 28 (p<0.05), and the mixture of lutein and monohydroxyl pigment promoted the yellow scores of shanks on day 14, 21, and 28 (p<0.05). The mixture of lutein and monohydroxyl pigment increased the yellow scores of beaks and all treatments enhanced the yellow of shanks on day 28 (p<0.05). In addition, all treatments improved the yellow (b*) values of breast and thigh muscle, moreover, the monohydroxyl pigment and the mixture of lutein and monohydroxyl pigment enhanced the values of redness (a*) and yellow (b*) of abdominal fat (p<0.05). Conclusion: In summary, different types of xanthophyll extracted from marigold significantly increased the yellow scores of skin color and the yellow (b*) values of carcass pigmentation. Especially, the mixture of lutein and monohydroxyl pigment was more efficient on skin color.

A Design of Block Cryptosystem using Multiple Nonlinear S-box Function (다중 비선형 S-box 함수를 이용한 블록 암호시스템 설계)

  • 정우열;이선근
    • Journal of the Korea Society of Computer and Information
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    • v.6 no.2
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    • pp.90-96
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    • 2001
  • The development of network and the other communication-network can generate serious social problems. So. it is highly required to control security of network. These problems related security will be developed and keep up to confront with anti-security part such as hacking. cracking. In this paper. the proposed multiple nonlinear S-box function which is capable to cipher regardless of key distribution or key-length for these definite problem is proposed and designed in hardware. The proposed multiple nonlinear S-box function increase secret level from using a nonlinear function in multiply for key data utilized in cryptography that generates MDP and MLP in maximum is proposed to prevent cryptography analysis. The designed the multiple nonlinear S-box function in this paper performed synthesization and simulation using Synopsys Ver. 1999.10 and VHDL

MDP(Markov Decision Process) Model for Prediction of Survivor Behavior based on Topographic Information (지형정보 기반 조난자 행동예측을 위한 마코프 의사결정과정 모형)

  • Jinho Son;Suhwan Kim
    • Journal of Intelligence and Information Systems
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    • v.29 no.2
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    • pp.101-114
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    • 2023
  • In the wartime, aircraft carrying out a mission to strike the enemy deep in the depth are exposed to the risk of being shoot down. As a key combat force in mordern warfare, it takes a lot of time, effot and national budget to train military flight personnel who operate high-tech weapon systems. Therefore, this study studied the path problem of predicting the route of emergency escape from enemy territory to the target point to avoid obstacles, and through this, the possibility of safe recovery of emergency escape military flight personnel was increased. based problem, transforming the problem into a TSP, VRP, and Dijkstra algorithm, and approaching it with an optimization technique. However, if this problem is approached in a network problem, it is difficult to reflect the dynamic factors and uncertainties of the battlefield environment that military flight personnel in distress will face. So, MDP suitable for modeling dynamic environments was applied and studied. In addition, GIS was used to obtain topographic information data, and in the process of designing the reward structure of MDP, topographic information was reflected in more detail so that the model could be more realistic than previous studies. In this study, value iteration algorithms and deterministic methods were used to derive a path that allows the military flight personnel in distress to move to the shortest distance while making the most of the topographical advantages. In addition, it was intended to add the reality of the model by adding actual topographic information and obstacles that the military flight personnel in distress can meet in the process of escape and escape. Through this, it was possible to predict through which route the military flight personnel would escape and escape in the actual situation. The model presented in this study can be applied to various operational situations through redesign of the reward structure. In actual situations, decision support based on scientific techniques that reflect various factors in predicting the escape route of the military flight personnel in distress and conducting combat search and rescue operations will be possible.