• The Journal of Internal Korean Medicine
• /
• v.39 no.1
• /
• pp.22-43
• /
• 2018

Objective: The purpose of this study is to investigate the effect of Cheonmagudeung-eum (CGE) for essential hypertension by systematic review and meta-analysis. Methods: The period of literature search was until October 30, 2016, and 14 electronic databases were utilized as search engines. The evaluation for the risk of bias (RoB) was conducted by using the Cochrane Risk of Bias Tool. The meta-analysis was performed by synthesizing outcome data, including total effective rate (TER), systolic blood pressure (SBP), diastolic blood pressure (DBP), and the incidence of adverse events. Result: There were a total of 64 RCTs using CGE on adult essential hypertension. In the RoB evaluation, most of the items were unclear, and the qualities of studies were rated low. The concurrent treatment of CGE and antihypertensive drug (AHD) showed a significant hypotensive effect since the risk ratio (RR) of TER was 1.17 times (95% CI 1.14, 1.20, p<0.01) higher than that of AHD alone. In addition, the mean difference (MD) appeared low as 8.73 mm/Hg in SBP (95% CI -11.36, -6.09, p<0.01) and 5.81 mm/Hg in DBP (95% CI -7.50, -4.12, p<0.01). Conclusion: Through this study, it was identified that the combined treatment of CGE and AHD on hypertension would be more effective than that of AHD treatment alone. However, due to the low quality of the selected original articles, the significance of this conclusion is somewhat limited, and we hope that this would be complemented through more rigorous RCTs in the future.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.1 no.1
• /
• pp.53-70
• /
• 2006

This study aims to provide policy suggestions on how to implement the process of empowerment, by investigating the conditions that hinder the process and the attitude of the KBS employees. For the cross-sectional study, this thesis examined the domestic and international references, conducted a survey of KBS employees, personal interviews and made direct observations. Approximately 1,200 copies of the questionnaire were distributed and 474 were completed and returned. The analysis used SPSS 12.0 software to process the data collected from 460 respondents. The survey findings showed a decrease of 24.2%p in the number of responses expressing negative views of the team structure and a decrease of 1.29%p in the number of positive responses. The findings indicated a positive transformation illustrating employees' improved understanding and approval of the team structure. However, KBS must address the issue on an ongoing basis. It has been proven that the employee empowerment increases the productivity of the individual and the group. In order to boost the level of empowerment, the management must exercise new, innovative leadership and build trust between the managers and the employees first. Additional workload as a result of shirking at work places was prevalent throughout all divisions and ranks, according to the survey data. This outcome leads to the conclusion that the workload is not evenly distributed or shared. And the data also showed the employees do not trust the assessment and rewards system. More attention and consideration must be paid to the team size and job allocation in order to address this matter; the present assessment and rewards system need to be complemented. The type of leadership varies depending on the characteristics of the organization's structure and employees' disposition. KBS must develop and reform its own management, leadership style to suit the characteristics of individual teams. Finally, for a soft-landing of KBS team structure, in-house training and education are necessary.

• Child Health Nursing Research
• /
• v.8 no.3
• /
• pp.260-271
• /
• 2002

This study was performed to identify the level of stress recognized by the parents as a support system for their infant patients who were hospitalized in an emergency department, thus to provide the resulting data as the basic material of care intervention for the families of infant patients. This study subjected the parents with infant patients who were hospitalized in emergency department of C University Hospital in Daejeon, and the data was collected from questionnaires for them, dating from Mar. 20, to Jun. 24, 2001 This study used the tool(30 questions) which was originally developed by Ji, Dong-ok (1992) for measuring the stress of families of infant patients in emergency room, and then was modified and complemented by this researcher suitably for infant patients. Collected data was statistically analyzed with frequency, percentage, mean, standard deviation, t-test, ANOVA, by using SPSS WIN10.0 program, and the results were as follows: 1. The stress of parents with infant patients hospitalized in emergency department averaged 3.31 on the basis of 5-point measure, which means that they felt stress beyond means. 2. The factor with high average out of stress factors the parents of infant patients recognized included the followings: 'about the pain of infant patients due to examination(3.91±1.00)'; 'about rare opportunity to be in contact with physician(3.78±1.09)'; 'delay in emergent treatment required for infant patients(3.75±1.31)'; 'delay in the general treatment of infant patients(3.72±1.32)'. Factors of the stress level includes the followings: 'care and medical treatment'(3.46±.72); 'body and diseases'(3.41±.97)'; 'lack of information and supportable resources (3.25±.77)'; and so on. 3. For the stress level according to general characteristics, there were statistically significant differences in the result of the condition of infant patients, medical treatment(P<.01), religion, the procedure of treatment(P<.05). With little preceding studies for infant patients hospitalized in emergency department, this study looked through the level of stress recognized by the parents of infant patients. Based on the comprehension on the parents with infant patients and the knowledge on stress factors recognized by the parents, it is expected that we can seek the methods of care intervention such as explanation of care and treatment procedures, unit policies, continuous interest and emotional supports as well as the provision of information to understand the responses of parents and reduce accompanied stresses.

• Research in Community and Public Health Nursing
• /
• v.12 no.3
• /
• pp.773-784
• /
• 2001

The study was conducted to test the effectiveness of thermotherapy for high school girls who suffered from disruption in school activities through dysmenorrhea, and to study the extent of its availability in school infirmaries as one of the nursing methods. The test for the study was designed to make a contrast between half of the subjects (20) who did not receive the thermotherapy, and the rest (20) who did during the period from February 15th to April 14th, 2001. Measurements were taken of the subjects who complained of painful menstruation by a set of variables. The variables that were established and complemented by Hur, Mung-heang (1985) consist of 29 items that assess the dysmenorrhea and vitality through the symptoms of primary menstruation visually. Spsswin was used to analyze the data. The Cronbach-${\alpha}$ method was used for statistic confidence, and the test effect of both the subjects and the contrary ones was analyzed by way of T-test. The conclusions are as follow. (1) The hypothesis 1 states that the subjects with themotherapy have a lower degree of dysmenorrhea rather than the contrary ones without it. By the above assessment, there was a quantitative difference between the subjects at 39.40, and the contrary ones at 22.0. After the themotherapy, the degree of dysmenorrhea in the subjects was low indicating that there is a still 5% chance of statistic meaningful difference (t= 2.651. P= .012). As a result, the first hypothesis was accepted. (2) The hypothesis 2 states that the subjects with themotherapy have a different primary menstruation than those without. Data indicate that there was a difference of -5.95 and -4.80. The subjects showed low degrees. Since it was statistically insignificant (t=-1.398, P=.170), the second hypothesis was rejected. (3) The hypothesis 3 states that the subjects with themotherapy have a different vitality. The vitality was measured in three aspects. (1) pulse rate (/min) The hypothesis 3' states that the subjects with themotherapy have the different pulse rate from those without. Data indicate that there was no statistically meaningful difference between the two groups (t=.237, P=. 814). Therefore, the third 1st hypothesis was rejected. (2) Respiration rate The hypothesis 3' states that the subjects with themotherapy have a different respiration rate between pre-thermotherapy and post-thermotherapy. in contrast with the ones without it. The data show that there was no statistically meaningful difference (t=.133. P=.895). A little respiration rate difference was shown between pre-and post-. Likewise. the third 2nd hypothesis was rejected. (3) Blood pressure In the 3rd sub-hypothesis that there would be a difference between experimental and controlled groups was also rejected. because there was no statistically significant difference between the contracting blood pressure and the relaxing blood pressure. In terms of vitality. the pulse rate, respiration rate and blood pressure have no statistical meaning but the first two ones show the decreasing in the rate. In short, though exclusive studies focused on thermo therapy have not been conducted and the comparison can not be made, this study shows not only that the thermotherapy is very effective to dysmenorrhea, but also that it can be available in school infirmaries as one of the nursing methods.

• Korea journal of population studies
• /
• v.32 no.1
• /
• pp.139-164
• /
• 2009

The first demographic transition refers to the historical decline in mortality and fertility, as shown from the 18th Century in several European populations, and continuing present in most developing countries. The end point of the first demographic transition(FDT) was supposed to be a stationary and stable population corresponding with replacement fertility and zero population growth. In addition, households in all parts of the world would converge toward the nuclear and conjugal types, composed of married couples and their offspring. The second demographic transition(SDT), on the other hand, sees no such equilibrium as the end-point. Rather, new developments bring sub-replacement fertility, a multitude of living arrangements other than marriage, and the disconnection between marriage and procreation. Populations would face declining sizes if not complemented by new migrants. Over the last decades birth rates have been on the decline in all countries of the world, and it is estimated that already more than half of he world's population has below replacement level fertility. Measured in terms of the Total Fertility Rate (TFR), currently 34 countries have fertility levels of 1.5 or less. Similarly, Korea has been below lowest-low fertility for eight consecutive years since 2001 and below the replacement level for more than twenty years. In explaining the low fertility in Korea, some researchers explain the low fertility as revenge against a male-dominated society and institution, while others focus the impact of the employment instability. These studies share the basic ideas (spread of individualism, delayed marriage and childbearing, high divorce rate etc.) of a second demographic transition in order to explain the low fertility in Korea.

• Journal of the Korean Regional Science Association
• /
• v.40 no.1
• /
• pp.37-51
• /
• 2024

To respond to local extinction, South Korea, under the leadership of the Ministry of the Interior and Safety, identified depopulated areas in 2021 and launched the Local Extinction Response Fund in 2022. However, due to its early stage of implementation, analyzing the characteristics and changes of policy response to local extinction at the central government level remains a challenge. In contrast, Japan, facing similar issues of local extinction as South Korea, has established a robust central government-led response system based on the Regional Revitalization Act and the Comprehensive Strategy and Basic Policy on Community-Population-Job Creation. Hence, this study examines Japan's policy responses to local extinction by analyzing the first and second periods of the Comprehensive Strategy and Basic Policy on Community-Population-Job Creation. For the analysis, topic modeling was employed to enhance text analysis efficiency and accuracy, complemented by expert interviews for validation. The results revealed that the first-period strategy's topics encompassed economy and society, start-up, local government, living condition, service, and industry. Meanwhile, the second-period strategy's topics included resource, the New Normal, woman, digital transformation, industry, region, public-private partnership, and population. The analysis highlights that the policy target, policy direction, and environmental change significantly influenced these policy shifts.

• The Korean Journal of Food And Nutrition
• /
• v.23 no.4
• /
• pp.526-530
• /
• 2010

Isopentenyl diphosphate(IPP) isomerization to dimethylallyl diphosphate(DMAPP) is an important step for the efficient production of isoprenoids such as lycopene, ${\beta}$-carotene, astaxanthin, etc. The type II isopentenyl diphosphate isomerase gene from Synechocystis sp. PCC6803(sll1556, Syidi2) was cloned and expressed in Escherichia coli $DH5{\alpha}$. When E. coli $DH5{\alpha}$ harboring lycopene synthesis genes, crtE, crtB, and crtI and mevalonate pathway genes, MvK1, MvK2, and Mvd, was cultured on LB medium containing mevalonate, the strain grew very slowly be due to the toxicity of isopentenyl diphosphate derived from mevalonate. When Syidi2 was introduced to E. coli $DH5{\alpha}$ harboring the lycopene synthesis genes and mevalonate pathway genes, growth on mevalonate medium was fully restored and the colony showed red color indicating lycopene formation. The growth rate of the mutant strain, E. coli $DH5{\alpha}$(idi::${\Delta}km$), was very slow because of IPP accumulation and DMAPP deprivation. Ultimately the idi mutant was complemented by introducing the Syidi2 gene.

• The Korean Journal of Emergency Medical Services
• /
• v.6 no.1
• /
• pp.103-128
• /
• 2002

As a result of trying the various manufacturing methods considering the reality of manpower and equipments with this manual, the following standardized procedures and contents can be suggested. (1) Since tools presenting Rock-Drill data must formalize the order of explanation although explainers are different, it will be valid that it is configured by existing power point method rather than by web document type. Composition of contents are selected on the basis of defence card and survey and then 8 items including initial screen, peripheral conditions, mobilization route, general conditions, use and structure by floor, department of vehicle consideration in activities and end screen are included. (2) Making methods and cautions of data included and used in power point are as follows ; - It was most effective that objects of fire fighting and location of neighboring fire fighting water were expressed by electronic map and drawing of inner building was made by scanning it after paining general architecture drawing(plan by each floor) rather than using drawing tools of EXCEL program or CAD drawing. And it was helpful to simplify contents of architecture drawing to wall, stairs and gate in understanding them. - Photographing of video data should be taken to show available fire fighting facilities in fire, use of planned space and the whole inner structure of each floor from the inside of fire fighting buildings and to display play time between 10 sec. and 1 min, for obstacles to distance from adjacent buildings or passage of special vehicles and fire fighting water from the outside of the building. - File format of video data taken in this way is most suitable to use wmv(window media video) or asf(advanced streaming format) type in consideration of time required for export, screen quality, file capacity and play type in Rock-Drill through network. - Still screen(photo) is more effective to express the department of fire fighting vehicles or other equipments than using video. (3) In configuration work of power point, hyper link was used most and configured to see any part at any situation like web document and then uniformity of presentation order of power point was complemented. (4) In case of sales facilities with the area of $35.557m^2$, the time of 22 hours and 30 minutes for five days was taken with five persons. Therefore, when eight-hour works a day were calculated, the whole process of video work for Rock-Drill can be finished with three day works.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.20 no.4
• /
• pp.136-143
• /
• 2016

There are various method for evaluating the durability life of concrete structures due to salt damage. The best way is to perform a corrosion test for a rebar embedded in concrete specimen was exposure to marine environment. However, this method has the disadvantage that it takes a long period of time. Also, accelerated corrosion test which was complemented complements the time-consuming weakness is limited to apply because it could not reveal a correlation between long-term exposure test. Accordingly, the purpose of this study is to derive a correlation coefficient between cycle drying-wetting accelerated corrosion test and long-term exposure test. Corrosion initiation time was measured in four types of concrete samples, i.e., two samples mixed with fly ash(FA) and blast furnace slag(BS), and the other two samples having two water/cement ratio(W/C = 0.6, 0.35) without admixture(OPC 60 and OPC 35). The accelerated corrosion test was carried out by two case, i.e., one is a cyclic drying-wetting method(case 1), and the other is a artificial seawater ponding test method(case 2). Whether corrosion occurs, it was measures using half-cell potential method. The results indicated that case 1 is to accelerated the corrosion of rebar about 24~36% as compared with case 2, then the corrosion of rebar embedded in concrete occurred according to the order of OPC60, FA, BS, OPC35. Correlation coefficient between accelerated corrosion test and long-term exposure test, case 1 is 4.23 to 5.42, and case 2 is 6.54 to 7.82.

• Journal of Technology Innovation
• /
• v.17 no.2
• /
• pp.131-158
• /
• 2009

We examine the effects of environmental or organizational factors on the performance of TLOs(technology transfer offices) in the PRIs(Public research institutes) using SFA(Stochastic Frontier Analysis), a technique for estimating the efficiency of DMUs(decision making units). In SFA, independent variables are assumed to determine the efficient production technique(production frontier) or affect the efficiency of DMUs. Previous researchs show that input variables such as number of personnel, R&D expenditure affect the production frontier while environmental or organizational variables affect the efficiency. We tried to estimate various types of models to find out whether environmental or organizational variables affect output variables differently from the previous research. Main empirical findings are as follows. First, R&D expenditure tends to increase all output variables considered. Second, environmental factors such as type of institutions and location of institutions affect the level of outputs. Third, organizational factors such as reward system for technology transfer also appear to affect the output variables. Fourth, environmental or organizational variables affect the production frontier directly rather than affect the efficiency of DMUs. Lastly, the efficiency of each DMU appear to be 1 or near to 1. Since almost all DMUs are equally efficient, it may not be effective to evaluate technology transfer activities of PRIs by efficiency criteria. We believe that this research should be complemented by additional data. More general types of production function need to be considered, and new techniques with concepts like output distance functions need to be developed to analyse multiple outputs simultaneously.