• Journal of agriculture & life science
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• v.45 no.6
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• pp.141-150
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• 2011

In order to elucidate a flavor characteristics of the low-salt fermented ascidian (LFA), a volatile flavor constituents were extracted and analyzed by SDE apparatus and GC/MS. Salinity, pH and volatile basic nitrogen of the LFA were 8.0%, 5.17 and 23.0 mg/100 g, respectively. Total content of volatile flavor compounds identified from the LFA was $1,221.42{\mu}g/100g$ as cyclohexanol (internal standard), it were composed of 23 alcohols ($644.85{\mu}g/100g$) such as 1-octanol and 2-pentanol, 16 acids ($293.91{\mu}g/100g$) such as 2-hydroxy-propanoic acid and butanoic acid, 15 aldehydes ($153.61{\mu}g/100g$) such as trans-2-hexanal and benzaldehyde, 29 hydrocarbons ($97.65{\mu}g/100g$) such as 1,4-dimehyl-cyclooctane and 1-nonene, six aromatic compounds ($6.20{\mu}g/100g$), two esters ($2.07{\mu}g/100g$), two nitrogen-containing compounds ($19.09{\mu}g/100g$) and three micellaneous compounds ($4.04{\mu}g/100g$).

• Analytical Science and Technology
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• v.6 no.1
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• pp.1-8
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• 1993

The purpose of this study is to investigate the elution behavior of monosubstituted phenols and benzenes in micellar liquid chromatographic system, $C_{18}$ column-anionic surfactant, sodium dodecyl sulfate(SDS). The partition coefficients between the micellar pseudophase-water and modified stationary phase-water are calculated by the relationship between solute retention and micellar mobile phase(SDS) composition. The free energy of transfer of solute from water to micelle is also calculated from these values. There is a direct correlation between the hydrophobicity parameters in MLC and corresponding partition data for 1-octanol-water, which indicates that the hydrophobicity of molecules plays an important role in the partition for both systems and that quantitative structure activity relationships(QSAR) are available from studies on micellar partition. The other purpose of this study is to investigate methylene selectivity of alkyl homologous series through correlation between retention and the number of carbons. The correlation between hydrophobicity parameters in MLC and 1-octanol-water partition data was also observed when n-propanol was as a modifier in the mobile phase.

• Korean Chemical Engineering Research
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• v.57 no.6
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• pp.790-803
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• 2019

The dioctyl terephthalic acid (DOTP) process produces plastic plasticizers by esterification of terephthalic acid with powder in the form of octanol. In this study, the dust explosion characteristics of terephthalic acid directly injected into the manhole in the form of powder in the presence of flammable solvent or vapor in the reactor of this process were investigated. Dust particle size and particle size distribution dust characteristics were investigated, and pyrolysis characteristics of dust were investigated to estimate fire and explosion characteristics and ignition temperature. Also, the minimum ignition energy experiment was performed to evaluate the explosion sensitivity. As a result, the average particle size of terephthalic acid powder was $143.433{\mu}m$. From the thermal analysis carried out under these particle size and particle size distribution conditions, the ignition temperature of the dust was about $253^{\circ}C$. The lower explosive limit (LEL) of the terephthalic acid was determined to be $50g/m^3$. The minimum ignition energy (MIE) for explosion sensitivity is (10 < MIE < 300) mJ, and the estimated minimum ignition energy (Es) based on the ignition probability is 210 mJ. The maximum explosion pressure ($P_{max}$) and the maximum explosion pressure rise rate $({\frac{dP}{dt}})_{max}$ of terephthalic acid dust were 7.1 bar and 511 bar/s, respectively. The dust explosion index (Kst) was 139 mbar/s, corresponding to the dust explosion grade St 1.

• The Korean Journal of Pain
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• v.6 no.1
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• pp.74-82
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• 1993

신선한 소의 대뇌피질로부터 synaptosomal plasma membrane vesicles(SPMV)를 분리하고 이 SPMV로부터 추출한 총지질(cholesterol과 각종 인지질 함유)로서 제제한 인공세포막(SPMVTL)에서의 n-alkanols 침투 정도를 형광 probe를 이용한 형광 소광법을 통하여 검색하였다. n-alkanols는 SPMVTL 외부 단층(outer monolayer)의 표면에 주로 분포하되 그 탄소수에 비례하여 소수성 부위에 분포되는 양이 증가되는 경향을 나타내었다(1-decanol은 예외). Methanol, ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, 1-hepatnol, 1-cotanol, 1-nonanol 및 1-decanol은 SPMVTL 외부 단층 표면(친수성 부위)에 분포되는 것이 소수성 부위에 분포되는 것에 비하여 각각 650, 288, 151.6, 69.5, 36.8, 11.9, 4.8, 1.6, 0.74, 2.1배가 된다는 것을 확인하였다. 1-decanol은 $C_{10}$인데도 불구하고 $C_8$인 1-octanol에 비하여 적은 양이 소수성 부위에 침투 분포되는 것이 확인되었다. 또한 n-alkanols는 저자등이 이미 보고한 SPMV에서의 경우보다도 본 연구에서의 SPMVTL의 경우가 현저하게 많은 양이 소수성 부위로 침투 분포된다는 것이 확인되었다.

• Biotechnology and Bioprocess Engineering:BBE
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• v.9 no.6
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• pp.454-458
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• 2004

A study of the POSE (predispersed solvent extraction) for succinic acid by colloidalliq­uid aphrons was conducted. The organic phase contaning TOA (tri-n-octylamine) and 1-octanol permits a selective extraction of succinic acid from its aqueous solution. There was no difference of the extractability of POSE and that of conventional mixer-settler type extraction. Taking into account the no mechanical mixing in POSE, it was concluded that the POSE process is more adaptive than the conventional mixer-settler type extraction process. From mass transfer analysis at the various concentration of TOA in counter-current continuous operation, the concentration of TOA had no influence on the mass transfer coefficient. The loading values in continuous POSE were almost same as those in batch operation.

• Biomolecules & Therapeutics
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• v.1 no.2
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• pp.204-210
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• 1993

The distribution and excretion of DWC-751, a new cephalosporin, were examined in rats and mice following a single intravenous administration. DWC-751 in plasma and urine was determined by both HPLC and microbiological assay. The plasma concentration of the drug declined biexponentially. The initial and terminal half lives of the drug were 3.0 and 28.3 min, respectively. Binding of the drug to plasma proteins was 42.3%. The distribution volume at steacly-state ($Vd_{ss}$) was only 0.341 ι/kg, which is well correlated with the low n-octanol/water partition coefficient of the drug ($K_{o/w{\cong}0$) Actually, the drug was distributed to liver, kidney and lung with very low organ/plasma concentration ratio. The drug, was excreted mainly via renal excretion, i.e., the total($CL_T$) and apparent renal($CL_{R}$) clearances of the drug were 10.8 and 7.5 ml/min/kg, respectively.

• Environmental Analysis Health and Toxicology
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• v.23 no.3
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• pp.201-211
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• 2008

This study was performed to find the atmospheric concentrations of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) at four different heights (l0, 50, 150 and 1,500 cm) using low volume polyurethane foam (PUF) plug air sampler in semi-rural area. ${\alpha}-/{\beta}-/{\gamma}-HCH$ with low molecular weights and Koa (octanol-air partitioning coefficient) in OCPs were similarly high concentrations at all heights, but the other OCPs (p,p'-DDE, p,p'-DDD, p,p'-DDT, Heptachlor epoxide, ${\gamma}$-CHL, ${\alpha}$-CHL, Trans-nonachlor) with high molecular weights and Koa decreased with increasing heights. However, the concentrations of PCBs increased with increasing height.

• Archives of Pharmacal Research
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• v.9 no.1
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• pp.49-54
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• 1986

Effect of sodium taurodeoxycholate (TDC) infused intravenously on the pharmacokinetics of methylene blue (MB) was studied in the rat to investigate the role of ion-pair complexation in the body on drug elimination and disposition. Distribution volume (Vd) of MB was increased significantly (p< 0.05) by TDC infusion. Considering together with the fact that apparent partition coefficient (APC) of MB between phosphate buffer (pH 7.4) and n-octanol was increased markedly by TDC, the increase in Vd seemed to be the result of decreased polarity of MB by ion-pair formation with TDC. But total body clearance (CLt) and biliary excretion clearance (CLbil) of MB were not increased significantly by TDC.

• Journal of Pharmaceutical Investigation
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• v.19 no.1
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• pp.21-27
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• 1989

Kinetic and thermodynamic aspects of the interface transfer of cefoperazone and its pivaloyloxymethyl ester were studied in a two-phase system composed of aqueous buffers and n-octanol by using the absolute reaction rate theory. In terms of the net thermodynamic parameters for the process, ${\Delta}S$ increased and ${\Delta}F$ decreased as the lipophilicity increased. With the increased ratio of forward $(k_f)$ to backward rate constants $(k_b)$, the ester was more lipophilic than cefoperazone, but the aqueous solubility was reduced.

• Food Science of Animal Resources
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• v.18 no.3
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• pp.255-260
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• 1998

The aroma concentrates from mold fermented sausages were isolated by steam distillation and simultaneous steam-distillation-extraction(SDE). methods. Quantitative estimation of the aroma concentrates in mold fermented sausages was carried out by using GC-MC. Mold fermented sausages were manufactured into two types. The first was manufactured with starter culture containing Lactobacillus plantarum and Staphylococcus carnosus(LP). The second was manufactured with starter culture containing L. curvatus and S. carnosus(LC). The aroma concentrates containing hexanoic acid and 2-butyl-2-octenal were identified in mold fermented sausages immediately after manufacture. After 28 days, the volatile flavor components from LP and LC were determined to be 14 (trimethylsilylester of hexadecanoic acid and 2-methyl-3-octanol, etc.) and 16 substances(hexadecanoic acid and 1-hexadecanol, etc.), respectively. The distribution of aroma concentrates in LP and LC was different, but their panel test placed them in similarity.