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Effects of a 12-week Combined Exercise Program on Gait Parameters in Elderly Women with Osteoarthritis

  • Lee, Jin
    • Korean Journal of Applied Biomechanics
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    • v.28 no.4
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    • pp.227-236
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    • 2018
  • Objective: The purpose of this study was to investigate the effects of a 12-week combined exercise program on gait parameters in elderly women with osteoarthritis. Method: The subjects of this study were 11 elderly women (age: $67.09{\pm}2.47$, height: $157.35{\pm}4.30cm$, weight: $62.49{\pm}6.36kg$) with knee osteoarthritis. The combined exercise program of this study was divided into aerobic exercise and lower extremity strengthening exercises. The exercises were performed for 60 minutes per session, three times a week, for a total of 12 weeks. The maximum joint moments of the hip, knee, and ankle joints with walking were obtained with 8-3D cameras (MX-T20, Vicon, USA) and 2-force plate (AMTI OR6-7-400, AMTI, USA). SPSS Windows version 23.0 was used for statistical analysis. A paired t-test was used for pre-post comparison. An alpha level of .05 was utilized in all tests. Results: The maximum extension moment was significantly higher in the hip joint after P1 on the X axis. The maximum joint moment of P3 in extension was statistically significantly lower after intervention. On the Z axis, the maximum joint moment was significantly lower after the exercise intervention at P3. There was a statistically significant increase in the extension moment of the left and right knee joints in the X axis after exercise intervention. In the right ankle joint, P1 (plantar flexion moment) showed a statistically significant high moment after exercise intervention. Conclusion: These results suggest that combined exercise, including lower limb and aerobic exercise, may have a positive effect on mobility and walking moments in patients with osteoarthritis of the knee.

Apoptosis Induction of HCT-15 Cells by Extracts of Undaria pinnatifida with Fermented Micro-organism (미역 발효추출물의 HCT-15 대장암 세포 사멸 유도 효과)

  • Kim, Tae-Yun;Han, Hyo-Sang;Lee, Young-Jong
    • The Korea Journal of Herbology
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    • v.28 no.4
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    • pp.33-40
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    • 2013
  • Objectives : To study the apoptosis effects of fermented Undaria pinnatifida extracts(FUP) against HCT-15 colon cancer cells. Method : By measuring cell proliferation, DNA fragmentation, cell cycle, morphology, and western blot from FUP, the study investigated the effects of the extractions had upon the HCT-15 colon cancer cells, and concluded that the inhibiting effects upon cells were induced by apoptosis. Result : FUP effectively inhibited the growth of HCT-15 colon cancer cells. After analyzing the DNA fragmentation, the study observed a DNA ladder, while examining the cells, and found an increase of sub-G1 hypodiploid cells. On the changes regarding the nucleus of the cells, a condensation of cells and chromatin, as well as an apoptotic body was clearly observed. By observing through western blot from FUP, the study found a decreased level of Bcl-2 from HCT-15 colon cancer cells, but the increased level of Bax and cleaved caspase-3, which as a result induced apoptosis, inhibiting the growth of HCT-15 colon cancer cells. FUP increased the natural death of HCT-15 colon cancer cells by the induction of apoptosis. FUP seemed to have no suppressing effect upon HL-60/MX2 cells. However, compared to the fucoidan, the study was able to clearly observe morphological changes of HCT-15 cells apoptosis, in a 1/2 concentration. Conclusion : FUP had antiproliferative effects on different kinds of cancer cells, while proving especially efficacious against colon cancer cells.

Changes in Temperature and Humidity in the Forest Caused by Development (도로에 의한 산림 내 온습도 변화)

  • Choi, Jaeyong;Park, Myung-Soo;Kim, Su-Kyung;Yu, Seung-Hyeon;Choi, Won-Tae;Song, Wonkyong;Kim, Whee-Moon;Kim, Seoung-Yeal;Lee, Ji-Young
    • Journal of Environmental Impact Assessment
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    • v.27 no.6
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    • pp.604-617
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    • 2018
  • As the depletion of forests became more widespread due to the increase in the number of roads, the research was conducted on the relationship between temperature and humidity in the forests, assuming that the forests around the roads were affected. Through the forest monitoring, the temperature and humidity of coniferous forests and broadleaf forests in Sedong and Gongju areas were observed at three point of 10m, 20m and 30m from the road boundary to the inside of the forest, respectively. In Yeongdong area, for more reliable results, it was observed from the point of 0m, 10m, and 20m. During the study period, so it was expected the change in tree growth was small, the change of temperature and humidity inside the forest by the road was compared with the temperature and humidity from the road to the inside of the forest from September 2017 to January 2018, the changes of temperature and humidity inside the forest due to linear development such as roads were quantitatively analyzed. Using the HOBO data logger (MX2301, Onset Corp.), the temperature and humidity changes of each site were measured, and the average of the changes have been analyzed monthly. In the case of Gongju coniferous forests in September 2017, the average weekly temperature is $0.57^{\circ}C$ higher than the forest outside from the forest boundary and $1.23^{\circ}C$ higher than the inside of the forest, at night in November 2017, in Sedong broadleaf forests. That is, the ability to control the temperature and humidity of the forests along the road was larger and less variable as the distance from the road boundary to the inside of the forest increased. In this study, it is considered that the high degree of change in temperature and humidity of the forest and the surrounding area due to artificial linear development such as roads will affect the growth of trees. This results could serve as a basis for studying the quantitative scope of linear development affecting forest growth and for managing forest change caused by linear development.

A Case of Neck Soft Tissue Infection in Patient with Nasopharyngeal Cancer; Misdiagnosed as Local Progression during External Radiotherapy (비인두암 환자에서 방사선 치료중 암의 국소진행으로 오인된 경부 연조직 감염 1례)

  • Lee So-Yeon;Im So-Hi;Choi Hyun-Cheul;Kim Sung-Hwan;Jun Jung-Soo;Back Joon-Hyun;Yoo Jin-Young;Noh He-Il;Kim Hoon-Kyo
    • Korean Journal of Head & Neck Oncology
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    • v.18 no.2
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    • pp.216-218
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    • 2002
  • A 38-year-old man, who was diagnosed nasopharyngeal carcinoma (stage T4N2Mx) had rapidly growing lower neck mass (at level IV area) with local inflammation sign during concurrent chemoradiotherapy. After we performed Color Doppler sonography and fine needle aspiration biopsy of the neck mass, we differentiated neck soft tissue infection from tumor extension. Size of the mass decreased after antibiotics therapy. It was difficult to differentiate neck infection from tumor progression during treatment in naspharyngeal carcinoma.

Development of 6-axis Ankle Force/Moment Sensor for an Intelligent Foot of a Humanoid Robot (인간형 로봇의 지능형 발을 위한 6축 발목 힘/모멘트센서)

  • Kim, Gab-Soon
    • Journal of the Korean Society for Precision Engineering
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    • v.24 no.1 s.190
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    • pp.27-36
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    • 2007
  • This paper describes the development of 6-axis ankle force/moment sensor for the intelligent feet of a humanoid robot. When the robot walks on uneven terrain, the feet should perceive the applied forces Fx, Fy, Fz and moments Mx, My, Mz from the attached 6-axis force/moment sensor on their ankles. Papers have already been published have some disadvantages in the size of the sensor, the rated output and so on. The rated output of each component sensor (6-axis ankle force/moment sensor) is very important to design the 6-axis force/moment sensor for precision measurement. Therefore, each sensor should be designed to get the similar rated output under each rated load. Also, the size of the sensor is very important for mounting to robot's feet. Therefore, the diameter should be below 100 mm and the height should be below 40mm. In this paper, first, the structure of a 6-axis ankle force/moment sensor was modeled for a humanoid robot's feet newly, Second, the equations to predict the strains on the sensing elements was derived, third, the size of the sensing elements was designed by using the equations, then, the sensor was fabricated by attaching straingages on the sensing elements, finally, the characteristic test of the developed sensor was carried out. The rated outputs from the derived equations agree well with the results from the experiments. The interference error of the sensor is less than 2.94%.

Effect of Sintering Atmosphere and Carbon Addition on Sintered Density of M3/2 Grade High Speed Steel Powder (M3/2계 고속도 공구강 분말의 소결분위기와 탄소첨가가 소결밀도에 미치는 영향)

  • Ahn, Jin-Hwan;Heo, Jong-Seo;Joo, Dong-Won;Jung, Eun;Sung, Jang-Hyun
    • Journal of Powder Materials
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    • v.5 no.4
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    • pp.265-272
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    • 1998
  • For the purpose of investigating the effect of sintering atmosphere and carbon addition on sintered density and microstructural characteristics, the M3/2 grade high speed steel powders with the addition of carbon are sintered in vacuum and $20%H_2/79%N_2/l%CH_4$ gas atmosphere. With the addition of 0 wt%C, 0.45wt%C and 1.15 wt%C the optimum sintering temperatures decrease down to $1260^{\circ}C$, $1210^{\circ}C$ and $1150^{\circ}C$ respectively for the vacuum sintered specimen, and also decrease down to $1130^{\circ}C$, $1120^{\circ}C$ and $1115^{\circ}C$ for the gas sintered specimen. The threshold temperatures for full densification decrease steeply with increasing carbon content of the sintered specimen, while this temperatures are slowly decreased at high carbon content. The vacuum sintered specimen shows the primary carbides of MC and $M_6C$ type at the optimum sintering temperature, and eutectic carbides of $M_2C$ and Fe-Cr type are produced in the oversintered specimen. The gas sintered specimen exhibits M6C and Fe-Cr type primary carbides at the optimum sintering temperature. The eutectic carbides of $M_6C$ and Fe-Cr type and MX type carbonitride are shown for the oversintered specimen in the gas atmosphere. The hardness of gas sintered specimen shows high value of 830-860 Hv due to the increment of carbide precipitation.

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The Comparative Study on Age-associated Gait Analysis in Normal Korean (우리나라 연령별 보행분석 비교연구)

  • Yoon, Na-Mi;Yoon, Hee-Jong;Park, Jang-Sung;Jeong, Hwa-Su;Kim, Geon
    • The Journal of Korean Physical Therapy
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    • v.22 no.2
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    • pp.15-23
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    • 2010
  • Purpose: This study was done to establish reference data for temporo-spatial, kinematic and kinetic parameters for normal Koreans as they age. Methods: Normal adults and children without a previous history of musculoskeletal problems were enrolled in this study. The normal subjects were divided by age into three groups: Group I: children ($11.95{\pm}0.29$ years); Group II: young adults ($23.90{\pm}3.67$ years); Group III: older adults ($71.40{\pm}4.08$ years). The temporo-spatial and kinematic data were measured using 6 MX3 cameras while each subject walked through a 10 m walkway at a self-selected speed. The kinetic data were measured using 2 force plates and were calculated by inverse dynamics. Results: Motion patterns are typically associated with a specific phase of the gait cycle. Our results were as follows: 1. There were significant differences between the different age groups in temporo-spatial parameters such as cadence, double support, time of foot off, stride length, step length, and walking speed. 2. There were significant differences between the groups in kinematic parameters such as range of motion (ROM) of the hip, knee and ankle in the sagittal plane, ROM of the pelvis, hip and knee in the coronal plane and ROM of the pelvis, hip and ankle in the transverse plane. 3. There were significant differences between the groups in kinetic parameters such as joint moments of force, joint mechanical power generation or absorption and ground reaction forces. Conclusion: The results of this study can be utilized (a) as a reference for kinematic and kinetic data of gait analysis in normal Koreans, and (b) as an aide in evaluating and treating patients who have problems relating to gait.

Characteristics of microstructure and mechanical strength of ASTM A387-Gr.91 Steel deteriorated under high-temperature (고온 열화된 ASTM A387-Gr. 91 강의 미세 조직 및 기계적 강도 특성)

  • Jeong, Gwang-Hu;Han, Min-Su;Kim, Seong-Jong
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2018.06a
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    • pp.111-111
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    • 2018
  • ASTM A387-Gr.91 강은 우수한 고온 강도, 크리이프 저항성 그리고 내산화성 등으로 인해 화력 및 바이오매스 발전 시설과 같은 고온 설비의 구조재료로 널리 사용되고 있다. 고온 환경에서 높은 강도는 탄화물과 탄질화물에 의한 석출강화가 주 요인으로 작용한다. 열처리 과정에서 Mo, Cr, Mn, 그리고 Fe는 구-오스테나이트 및 마르텐사이트 라스 입계에 $M_{23}C_6$ 탄화물로 석출되며, V, Nb, 및 N은 조직 내부에 미세한 MX 탄질화물로 석출된다. 따라서 합금의 고온 강도는 조직 내 석출물의 개수밀도와 크기에 크게 의존한다. 그러나 적용 환경의 특성 상 고온 노출에 따른 2차상 석출 및 조대화의 조직열화 현상이 발생하며, 이는 재료의 강도를 저하시킨다. 본 연구에서는 ASTM A387-Gr.91 강의 미세조직 열화에 따른 강도저하 및 파괴 양상을 고찰하는데 그 목적을 두었다. 본 연구에서 사용된 ASTM A387-Gr.91 강의 화학성분(wt, %)은 0.1 C, 0.38 Si, 0.46 Mn, 0.25 Ni, 8.38 Cr, 0.93 Mo, 0.18 V, 0.09 Nb, 그리고 나머지는 Fe 이다. 조직열화 및 기계적 강도저하 특성을 평가하기 위한 등온열화는 $650^{\circ}C$의 대기 환경에서 최대 1000시간동안 실시하였다. 열화된 시험편의 미세조직 및 탄화물에 대한 분석은 SEM과 EDS를 이용하여 실시하였다. 그리고 기계적 강도 평가는 인장실험과 비커스 경도시험을 통해 실시하였다. 또한 열화 시간에 따른 파단양상의 변화를 관찰하기 위해 인장시험편의 파단면을 SEM과 EDS를 이용하여 분석하였다. 그 결과, 열화에 따른 마르텐사이트 라스의 소실, 탄화물의 조대화, 그리고 2차상 석출의 조직 열화현상이 나타났다. 또한 기계적 강도는 조직 열화에 따라 저하되는 경향을 나타냈다.

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Electronic and Magnetic Structure Calculations of Diiron Enzymes (이중 철 효소의 전자구조 및 자기구조 계산)

  • Park, Key Taeck
    • Journal of the Korean Magnetics Society
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    • v.25 no.4
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    • pp.106-110
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    • 2015
  • We have studied electronic and magnetic structure of 2 kinds of diiron molecules using OpenMX method based on density functional method. The calculated density of states of diiron-2 is similar with that of diiron-4 because of equal number of 6 ligand atoms. The calculated total energy with antiferromagnetic spin configuration is lower than those of ferromagnetic configurations for both of them. The exchange interaction J of diiiron-4 between $Fe^{+3}$ atoms is one order larger than that of diiron-2, and the calculated J matches well with the experimental one. That comes from the short distance of Fe-O and the high O 2p energy levels. It derives a strong super exchange interaction. The angle of diiron-4 between Fe atoms is bigger than that of diiron-2. It also derives a strong super exchange interaction because of the ${\sigma}$-bond between Fe and O atoms.

PWHT Cracking Susceptibility in the Weld Heat-Affected Zone of Reduced Activation Ferritic/Martensitic Steels (핵융합로 구조용 저방사화강의 용접열영향부 후열처리 균열 감수성)

  • Lee, Jinjong;Moon, Joonoh;Lee, Chang-Hoon;Park, Jun-Young;LEE, Tae-Ho;Hong, Hyun-Uk;Cho, Kyung-Mox
    • Journal of Welding and Joining
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    • v.34 no.6
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    • pp.47-54
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    • 2016
  • Post-Weld Heat Treatment (PWHT) cracking susceptibility in the weld heat-affected zone (HAZ) of reduced activation ferritic-martensitic (RAFM) steels was evaluated through stress-rupture tests. 9Cr-1W based alloys including different C, Ta and Ti content were prepared. The coarse grained heat-affected zone (CGHAZ) samples were simulated with welding condition of 30 kJ/cm heat input. CGHAZ samples consisted of martensite matrix. Stress rupture experiments were carried out using a Gleeble simulator at temperatures of $650-750^{\circ}C$ and at stress levels of 125-550 MPa, corresponding to PWHT condition. The results revealed that PWHT cracking resistance was improved by Ti addition, i.e., Ti contributed to the formation of fine and stable MX precipitates and suppression of coarse M23C6 carbides, resulting in improvement of stress rupture ductility. Meanwhile, rupture strength increased with increasing solute C content.