• 한국대기환경학회지
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• 제23권5호
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• pp.539-546
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• 2007

Increasing emission of $CO_2$ significantly effects the global warming. Chemical absorption is one of separation methods of $CO_2$ from the industrial flue gases. In this study, the $CO_2$ removal efficiency as well as the $CO_2$ absorption amount of aqueous AMP (2-amino-2-methyl-1-propanol) solutions were measured using the continuous absorption and regeneration apparatus. We investigated the effect of aqueous AMP+AEPD(2-amino-2-ethyl-1, 3-propanediol) and AMP+TIPA (triisopropanolamine) solutions to enhance absorption characteristics of AMP. As a result of this study, the absorption amount and $CO_2$ removal efficiency were increased with adding TIPA into 30 wt.% AMP. The absorption amount and $CO_2$ removal efficiency of aqueous 30 wt.% AMP+5 wt.% TIPA solution were $1.70\;kg-CO_2/kg-absorbent$ and 91.1%, while those of aqueous 30 wt.% AMP solution were $1.58\;kg-CO_2/kg-absorbent$ and 89.3%. In addition, aqueous 30 wt.% AMP+5 wt.% TIPA solution used in the study revealed the high stripping efficiency, which was almost 98%, at the temperature of $110^{\circ}C$. Thus, the temperature of regenerator should be operated at $110^{\circ}C$.

• 한국식품과학회지
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• 제29권1호
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• pp.183-187
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• 1997

산분해 HVP제조 공정에서 부산물로 생성되는 DCP와 MCPD의 분석을 위한 GC-MS의 분석 조건 및 추출 조건 최적화를 수행하였다. DB-5 모세관 칼럼을 이용하여 DCP와 MCPD가 각각 분리되었으며 SIM기법을 사용한 결과 25-50 ppb까지 검출 한계를 낮출 수 있었다. 고체상 추출 칼럼의 종류, 희석액의 염 농도, 추출 유기용매의 종류 등에 따라 상이한 분석 결과를 보였으며 고체상 추출 칼럼 중에서는 normal phase가 적합하였고, 희석액의 염화나트륨의 농도가 20% (w/v)일 때 최대의 추출 회수율을 보였다. 고체상 추출시 용리제로 사용되는 유기용매의 극성이 회수율을 결정하는 중요한 인자인 것으로 밝혀졌다. MCPD와 DCP의 추출에 적합한 유기용매의 선정을 위하여 물에 섞이지 않으면서 DCP와 MCPD에 용해도가 높은 클로로포름, 에테르, 핵산과 에틸 아세테이트 등의 유기용매 및 각각의 혼합 용매를 용리제로 테스트한 결과 DCP의 경우 핵산이, MCPD의 경우 에틸아세테이트가 적합한 유기용매로 선정되었다. 이 때 DCP와 MCPD의 추출 회수율은 각각 100%와 95%이었다. HVP를 함유하는 식품 시료를 분석한 결과 DCP와 MCPD의 함량은 각각 1 ppm이하와 수십 ppm의 값을 보였다.

• 한국발생생물학회지:발생과생식
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• 제3권1호
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• pp.107-111
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• 1999

우리나라에서 진주양식의 대상패류인 진주조개 (Pinctada fucata martensii) 담륜자를 냉동보존하기 위하여 4가지 동해방지제를 사용하여 냉동실험을 실시하고, 적합한 동해방지제를 찾고자 하였다. 동해방지제인 dimethyl sulfoxide (DMSO), ethylene glycol, glycerol과 1, 2-propanediol을 희석액인 0.2 M sucrose에 각각 0.01, 0.1, 1.0과 2.0 M이 되도록 혼합한 다음, 10분간 평형상태를 유지한 후 냉동하였다. 냉동후 해동시킨 담륜자는 모든 동해방지제에서 농도가 증가할수록 생존율이 높아졌으나, 일부 세포내 함유물이 세포외로 유출되어 손상을 입은 개체도 보였다. 진주조개의 담륜자 냉동보존에 적합한 동해방지제는 1.0∼2.0 M의 DMSO와 ethylene gly-col로서 해동후 생존율이 82.8∼97.4%로 가장 높았다.

• Toxicological Research
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• 제31권3호
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• pp.313-319
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• 2015

3-Monochloro-1,2-propanediol (3-MCPD) and 1,3-dichloro-2-propanol (1,3-DCP) are not only produced in the manufacturing process of foodstuffs such as hydrolyzed vegetable proteins and soy sauce but are also formed by heat processing in the presence of fat and low water activity. 3-MCPD exists both in free and ester forms, and the ester form has been also detected in various foods. Free 3-MCPD and 1,3-DCP are classified as Group 2B by the International Agency for Research on Cancer. Although there is no data confirming the toxicity of either compound in humans, their toxicity was evidenced in animal experimentation or in vitro. Although few studies have been conducted, free 3-MCPD has been shown to have neurotoxicity, reproductive toxicity, and carcinogenicity. In contrast, 1,3-DCP only has mutagenic activity. The purpose of this study was to analyze 3-MCPD and 1,3-DCP in various foods using gas chromatography-mass spectrometry. 3-MCPD and 1,3-DCP were analyzed using phenyl boronic acid derivatization and the liquid-liquid extraction method, respectively. The analytical method for 3-MCPD and 1,3-DCP was validated in terms of linearity, limit of detection (LOD), limit of quantitation, accuracy and precision. Consequently, the LODs of 3-MCPD and 1,3-DCP in various matrices were identified to be in the ranges of 4.18~10.56 ng/g and 1.06~3.15 ng/g, respectively.

• 약학회지
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• 제30권3호
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• pp.121-127
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• 1986

Three new alkanol esters of d-2-(6-methoxy-2-naphthyl)propionic acid, NAPROXEN were synthesized by esterification of sodium naproxen with chloralcohols, such as 2-chloroethanol, 3-chloro-1, 2-propanediol and $\beta$-chloroethoxyethanol in dimethylformamide. These new esters were obtained with comparably high yield and identified by elemental analysis, UV, IR and NMR techniques.

• Clinical and Experimental Reproductive Medicine
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• 제24권2호
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• pp.253-259
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• 1997

Objective: To investigate effects of cryoprotectant and cryopreservation on the chromosome of the human immature oocytes. Design: Intact cumulus-enclosed immature oocytes were collected from unstimulated ovaries and divided into three groups, such as no treatment as control (group 1), only 1,2-propanediol (PROH)-treated (group 2), and cryopreserved oocytes (group 3). Oocytes in group 1, 2, and survived oocytes after cryopreservation in group 3 were cultured for 48 hours. Setting: Infertility Medical Center at the CHA General Hospital, Seoul, Korea. Patients: Oocytes were obtained from Patients undergoing gynecological surgery. Main Outcome Measures: Maturation rate, abnormality in chromosomes by fluorescence in situ hybridization (FISH). Results: There was no effect of PROH only treatment on the chromosomal abnormalities in group 2 compared to control oocytes (41.4% and 31.8%, respectively). Whereas significantly increased abnormalities in chromosome (77.8%) were found in group 3. Conclusions: Human oocytes matured in vitro after cryopreservation at the germinal vesicle (GV) stage showed increased incidence of chromosomal abnormalities. These abnormalities may impair the capacity for further development of the embryos derived from frozen-thawed oocytes.

• Clinical and Experimental Reproductive Medicine
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• 제20권1호
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• pp.31-36
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• 1993

The effects of freezing and 1,2-propanediol on early and late pronucleate stage mouse ova were investigated in terms of survival after thawing and development in vitro. The samples were divided into two groups according to different age in pronucleate ova: ova in(1) early pronuclear stage with two distant pronuclei at 18h after hCG injection, and (2) late pronuclear stage with adjacent pronuclei at 30h. Zygotes in the late pronuclear stage have been proven to be more resistant to 1,2-propanediol, showing a significantly higher developmental rate than zygotes in early stage (80.3 versus 66.3%, <0.05), but survival rate was similar in the two groups (91.0 versus 93.5%). After freezing and thawing, survival and developmental rates were decreased in both groups when compared to the control group (54.3 versus 92.3%, 47.7 versus 73.3%. respectively). And developmental rate in the late pronuclear stage zygotes showed significantly higher than in early (55.4 versus 40.0%) after thawing. In conclusion, early pronucleate mouse ova have a lower developmental capacity in vitro and a lower survival rate after freezing and thawing than late ova. These findings suggest that the timing of freezing could be important for survival and further development in vitro in cryopreservation of human pronucleate ova.

• 폴리머
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• 제35권2호
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• pp.146-151
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• 2011

폴리(에틸렌 나프탈레이트) 중합 시 2,6-dimethyl naphthalene dicarboxylate와 함께 사용되는 디올 화합물인 ethylene glycol(EG), 1,3-propanediol(PD) 그리고 1,4-butanediol(BD)의 사용에 따른 공중합체의 물성을 살펴보았다. EG와 함께 PD 혹은 BD를 40% 이내 첨가하는 경우 합성된 폴리에스터가 무정형을 유지함을 알 수 있으며 이는 열적 특성과 배향 특성, 그리고 기계적 특성을 저하시키는 반면 치수안정성을 증가시킴을 획인할 수 있어 합성 폴리에스터가 유연기판 소재로의 적용 가능성을 확인하였다.

• 한국수정란이식학회지
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• 제10권3호
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• pp.219-227
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• 1995

This study was investigated to test in vitro-maturation rate of bovine follicular oocytes freezability of in vitro-matured bovine follicular oocytes with different stock solution in Glycerol and Propanediol, freezability of in vitro-rnatured bovine follicular oocytes on cryoprotectants, the viability of in vitro-rnatured bovine follicular oocytes by morphologically normal and FDA staining method. 1. The maturation rates of bovine follicular oocytes classified as grade A, B and C was 88, 63 and 21%, respectively. 2. Freezability of in vitro-matured bovine follicular oocytes on stock solution, TCM-199+5% FCS and m-PBS + 5% FCS was 61%(n=105), 48%(n=62) in $_1$M Glycerol and freeability of in vitro-matured bovine follicular oocytes on stock solution, TCM-199 +5% FCS and m-PBS + 5% FCS was 68%(n=112), 42%(n=57) in 1~2 Propanediol. The results indicate that freezability of in vitro-matured bovine follicular oocytes with different stock solution is important. 3. Freezability of in vitro-matured bovine follicular oocytes on cryoprotectants was Glycerol and PROH was 56%(n=167), 57%(n=169). The results indicate that PROH was superior to Glycerol. 4. The rates of morphologically normal IVM oocytes after thawing of cryopreserved oocytes with Glycerol and PROH were 39%(n=$_1$8), 65%(n=39), respectively. The results indicate that PROH was superior to Glycerol. 5. The fluorescent light intensity after thawing of cryopreserved oocytes classified with Positive, Partial-I, Partial-II, Negative with Glycerol and PROH. The results of FDA-positive 24%, 42%, Partial-I 17%, 10%, Partial- H 20%, 12%, FDA-negative 39%, 37%, and Partial-I, II, respectively.

• 대한생식의학회:학술대회논문집
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• 대한불임학회 1994년도 추계 학술대회 및 정기총회
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• pp.28-29
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• 1994