• 한국축산식품학회지
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• 제25권4호
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• pp.391-396
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• 2005

재래돼지 수컷과 랜드레이스 암컷을 교배하여 생산된 $F_1$ 182두의 등지방 두께(<11.80mm, $11.80\~25.01mm$, 25.01mm<)에 따른 돼지의 도체 특성, 이화학적 특성 및 지방산 조성을 비교한 결과는 다음과 같다. 등지방 두께가 25.01mm<그룹이 <11.80mm와 $11.80\~25.01mm$ 그룹에 비해 생체중, 도체중 및 지육률은 높았지만, 최종 등급은 낮았다. 등지방 두께가 25.01mm< 그룹이 <11.80mm와 $11.80\~25.01mm$그룹에 비해 pH가 높았고, 전단가는 가장 낮았다. 등지방 두께에 따른 수분, 조지방 함량 및 가열 감량은 차이가 없었다. 등지방 두께가 25.01m<그룹이 <11.80mm와 $11.80\~25.01mm$ 그룹에 비해 경도가 높았다. 등지방 두께가 25.01mm< 그룹이 <11.80mm와 $11.80\~25.01mm$ 그룹의 육 및 지방색의 황색도$(b^*)$는 낮았다. 등지방 두께가 25.01mm< 그룹이 <11.80mm와 $11.80\~25.01mm$ 그룹에 비해 stearic acid와 saturated fatty acid 함량이 높았지만 linoleic acid와 unsaturated fatty acid 함량은 낮았다. 이상의 결과를 요약하면, 등지방 두께에 따라 최종 등급, 황색도$(b^*)$ 및 지방산 조성에서 차이를 보였지만, 등지방 두께가 25.01mm< 그룹은 전단가가 낮고 pH가 높아 돈육의 품질 특성이 양호한 것으로 나타났다.

• 한국산학기술학회논문지
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• 제14권6호
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• pp.2735-2742
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• 2013

본 연구는 국가자료인 2010년도 국민건강영양조사 자료를 이용하여 20세 이상 성인에서 비타민 D와 맥압의 관련성을 평가하고자 실시하였다. 연구결과에서 PP에 양의 상관관계를 보이는 변수는 연령(p<0.01), TG(p<0.01), TC(p<0.01), FBS (p<0.01), BMI(p<0.01), 허리둘레(p<0.01) 등이었고, 음의 상관관계를 보이는 경우는 HDL-C(p<0.01), 신장(p<0.01), 체중(p<0.01), 25(OH)D(p<0.01) 등이었다. 연령, 신장, 체중, 허리둘레, BMI, TC, TG, HDL-C, FBS, 25(OH)D 등의 독립변수를 사용한 다중선형회귀분석결과에서, PP에 영향을 주는 독립변수는 연령(p<0.001)과 허리둘레(p<0.001), FBS (p<0.001), 25(OH)D(p<0.001), TC(p<0.001), 체중(p<0.001), HDL-C(p<0.001) 등이었다. 결론적으로, 비타민 D의 감소가 PP증가에 영향을 주는 요인이었으며, 비타민 D를 적정수준으로 유지 하는 것은 관상동맥질환의 발생률을 감소시킬 수 있을 것으로 기대된다.

• 한국치위생학회지
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• 제14권4호
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• pp.601-608
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• 2014

Objectives : The purpose of the study is to examine the apoptotic effects of Pseudomonas aeruginosa exotoxin A(PEA) in squamous cell carcinoma(SCC) 25 cells. Methods : Cell growth reduction and apoptosis induced by PEA were confirmed by WST-1 assay, Hoechst 33258 staining, flow cytometry analysis, and Western blot assay. Results : The PEA treatment decreased the cell viability in a dose and time dependent manner: control; $100{\pm}0^e$(p<0.01), 0.1875 nM; $87{\pm}4.36^d$(p<0.01), 0.375 nM; $82{\pm}0.58^d$(p<0.01), 0.75 nM; $72{\pm}1.67^c$(p<0.01), 1.5 nM; $51{\pm}1.53^{bc}$(p<0.01), 7.5 nM; $31{\pm}1.20^{ab}$(p<0.01), 15 nM; $26{\pm}0.67^a$(p<0.01), control; $100{\pm}0^a$(p<0.05), 24 h; $51{\pm}1.53^b$(p<0.05), 48 h; $16{\pm}0.5^c$(p<0.05), 72 h; $12{\pm}1.67^d$%(p<0.05). The PEA was observed on SCC 25 cells with the half maximal inhibitory concentration(IC50) value of 1.5 nM at 24 hours. The PEA treated SCC 25 cells demonstrated several types of apoptotic indications, such as nuclear condensation, the increase of sub G1, and the cleavage of PARP-1 and DFF 45. Conclusions : PEA showed anti-cancer activity against SCC 25 cells via apoptosis. PEA may potentially contribute to human oral cancer treatment.

• 치과방사선
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• 제27권1호
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• pp.55-71
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• 1997

Digora/sup (R)/ an intraoral digital radiography system utilizing image plate (IP) - has a dynamic range of exposure time which allows it to decrease the patient's exposure time and to increase diagnostic ability through image processing, transmission and storage. The purpose of this study was to evaluate the Digora/sup (R)/ system by assessing the effects of various exposure times on the detectability on the tip of the endodontic file. Examining the root canals of 45 extracted sound premolars, K -files No. 10, 15, and 20 were placed at slightly varying distances from the apex. The teeth were glued onto resin-plaster blocks. Five exposure times varying between 0.01 seconds and 0.25 seconds were used. Four observers were asked to measure the distance between the tip of the file and a reduction of crown portion, and obtained mean errors (subtracting true file length from the measured file length), comparing Digora/sup (R)/ monitors with E-plus films, which were both obtained under the same geometrical positions. The results were as follows : 1. Comparing E-plus film with Digora/sup (R)/ at 0.01 seconds, the mean errors in E-plus film showed -4.453 nun, -4.497 nun, and -3.857 nun, while the mean errors in Digora/sup (R)/ showed 0.065 nun, 0.607 nun, and 0.719 mm according to the file groups. Therefore there was a significant difference between E-plus film and Digora/sup (R)/(p<0.05). 2. By comparison of mean errors according to the various exposure times in the Digora/sup (R)/ system, the mean error at 0.01 seconds was significantly lower than that at 0.12 and 0.25 seconds in the No. 10 file group(p<0.05). And the standard deviation was the highest at 0.01 seconds. 3. Comparing E-plus film at 0.25 seconds with the Digora/sup (R)/ system, the mean errors showed a significant difference between E-plus film at 0.25 seconds and the Digora/sup (R)/ system at 0.25 seconds in No. 10 and 20 file groups(p<0.05). 4. Comparing E -plus film at 0.25 seconds with other exposure times, the mean errors showed a significant difference between E-plus film at 0.25 seconds and E-plus film at 0 .. 01 and 0.03 seconds in 10 file group(p<0.05). In the No. 15 and 20 file groups, there was a significant difference between E-plus film at 0.25 seconds and E-plus film at 0.01 seconds(p<0.05). In conclusion, Digora/sup (R)/ was better than E-plus film in detectability on the tip of the file at the exposure time of 0.01 seconds in all file groups. And we concluded that Digora/sup (R)/ can shorten exposure times up to 4％ of 0.25 seconds (0.01 sec), which is adequate exposure time for premolar in E-plus film using No. 15 and 20 files.

• 한국동물학회지
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• 제30권2호
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• pp.99-106
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• 1987

It is the purpose to investigate the physiological toxity and mutagenicity by heavy metal compounds such as potasium dichromate, sodium arsenite and selenium dioxide on the development of Drosophila melanogaster. These chemical compounds were highly toxic at every developmental stage of Drosophila. The relative values of fecundity, viability and developmental time obtained on food media containing 5 different levels of potasium dichromate (500, 600, 700, 800, and 900 ppm), also 5 different levels of sodium arsenite and selenium dioxide (10, 15, 20, 25 and 30 ppm). Resulting in the relative values of fecundity and viability generally decreased, on the contrary developmental time generally reduced as the concentration of chemicals in the food increased. A significant reduction in the fecundity was observed between 800 and 900 ppm (p<0. 01) on the potasium dichromate media, between 15 and 20 ppm (p<0. 05) on the sodium arsenite media, between 20 and 25 ppm (p<0. 02) on the selenium dioxide media. A significant reduction in the viability was observed between 700 and 800 ppm (p<0. 01) on the potasium dioxide media, between 25 and 30 ppm (p<0. 01) on the sodium arsenite media, between 20 and 25 ppm (p<0. 01) on the selenium dioxide media. The developmental time was significantly reduced between 800 and 900 ppm (p<0. 001) on the potasium dioxide media, between 15 and 20 ppm (p<0. 001) on the sodium arsenite media, and between 25 and 30 ppm (p<0. 01) on the selenium dioxide media.

• 한국동물학회지
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• 제30권2호
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• pp.107-116
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• 1987

It is the purpose to investigate the physiological toxity and mutagenicity by heavy metal compounds such as potasium dichromate, sodium arsenite and selenium dioxide on the development of Drosophila melanogaster. These chemical compounds were highly toxic at every developmental stage of Drosophila. The relative values of fecundity, viability and developmental time obtained on food media containing 5 different levels of potasium dichromate (500, 600, 700, 800, and 900 ppm), also 5 different levels of sodium arsenite and selenium dioxide (10, 15, 20, 25 and 30 ppm). Resulting in the relative values of fecundity and viability generally decreased, on the contrary developmental time generally reduced as the concentration of chemicals in the food increased. A significant reduction in the fecundity was observed between 800 and 900 ppm (p<0. 01) on the potasium dichromate media, between 15 and 20 ppm (p<0. 05) on the sodium arsenite media, between 20 and 25 ppm (p<0. 02) on the selenium dioxide media. A significant reduction in the viability was observed between 700 and 800 ppm (p<0. 01) on the potasium dioxide media, between 25 and 30 ppm (p<0. 01) on the sodium arsenite media, between 20 and 25 ppm (p<0. 01) on the selenium dioxide media. The developmental time was significantly reduced between 800 and 900 ppm (p<0. 001) on the potasium dioxide media, between 15 and 20 ppm (p<0. 001) on the sodium arsenite media, and between 25 and 30 ppm (p<0. 01) on the selenium dioxide media.

• 치위생과학회지
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• 제8권4호
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• pp.337-345
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• 2008

본 연구는 울산지역 일부 치과의료 기관에 근무하는 치과위생사를 대상으로 직무스트레스 파악하여 스트레스 주원인과 관리방안을 모색하기 위한 기초 자료를 제공하고자 조사한바 다음과 같은 결과를 얻었다. 1. 총 168명 중 연령은 25세 이하가 66.1%였으며 결혼상태는 미혼이 87.5%였다. 업무영역에서 진료 담당이 86.9%로 대부분을 차지하였으며 현 직장 근무경력별로는 1~4년 미만이 47.6%로 가장 높았다. 월평균 보수는 100~150만원 미만이 63.7%, 1일 평균 근무 시간은 8시간 이하가 57.1%였으며 주 5일 근무를 실시하는 경우가 58.3%, 야간 진료를 실시하는 경우가 78.0%였다. 2. 치과위생사의 직무스트레스를 분석한 결과 물리환경으로 인한 스트레스는 25세 이하가 26세 이상보다 높았으며(p < 0.05), 월평균 보수가 적을수록(p < 0.05), 하루 평균근무시간이 길수록(p < 0.01) 높았다. 직무요구로 인한 스트레스는 야간 진료를 실시하는 종사자(p < 0.05)와 주5일 근무를 실하는 종사자(p < 0.05)가 높았다. 직무자율로 인한 스트레스는 현 직장 근무경력이 많을수록(p < 0.01), 월평균 보수가 많을수록 높았고(p < 0.01), 직무 불안정에 인한 스트레스는 미혼이 기혼보다 높았다(p < 0.05). 조직체계 스트레스는 하루 평균 근무시간이 많을수록(p < 0.05) 높았고, 직장 문화로 인한 스트레스는 25세 이하가 (p < 0.01), 월평균 보수가 많을수록(p < 0.05), 주 5일 근무를 실시하는 종사자가 높았다(p < 0.05).

• 대한임상검사과학회지
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• 제36권2호
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• pp.199-204
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• 2004

Height has become one of the most important factors to determine the pulmonary function test index, and there is a high correlation between them, so that they have been utilized for evaluating pulmonary function test predictive value or nomogram. Therefore, we have tried to find out that difference and if there is any correlation and linear relationship between height and forced expiratory flow curve. There were a total of 163 subjects, male 93 and female 70. This study was done at the Department of Pulmonary Function Test of Jeon-Ju Presbyterian Hospital and we measured the index at the forced expiratory flow curve of FVC, $FEV_{1.0}$, $FEV_{1.0}$/FVC, $FEF_{25-75%}$, and $FEF_{200-1200m{\ell}}$. When we subjected the group of height more than 160cm, there were gradual increments at FVC(p<0.001), $FEV_{1.0}$(p<0.001), $FEF_{25-75%}$(p<0.05) and $FEF_{200-1200m{\ell}}$(p<0.001), but no changes at $FEV_{1.0}$/FVC in terms of forced expiratory flow curve index. We have analyzed the relationship between height and forced expiratory flow curve, there was a close relationship at FVC(r=0.670, p<0.01), $FEV_{1.0}$(r=0.491, p<0.01), $FEF_{25-75%}$ (r=0.175, p<0.05) and $FEF_{200-1200m{\ell}}$(r=0.370, p<0.01) but there was reciprocal relationship at $FEV_{1.0}$/FVC(r=-0.215, p<0.01). We have tried simple regression analysis to see if height affects forced expiratory flow curve index as a sector, and the result was $FVC(\ell)=0.0642{\times}height(cm)-7.2978$(p<0.01, $R^2=0.449$), $FEV_{1.0}(\ell)=0.0407{\times}height(cm)-4.2774$ (p<0.01, $R^2=0.2411$), $FEV_{1.0}/FVC(%)=-0.2892{\times}height(cm)+121.44$(p<0.01, $R^2=0.0464$), $FEF_{25-75%}(\ell/sec)=0.0176{\times}height(cm)-0.7876$(p<0.05, $R^2=0.0237$), $FEF_{200-1200m{\ell}}(\ell/sec)=0.0967{\times}height(cm)-11.037$(p<0.01, $R^2=0.1214$) this was approved statistically. According to this study, if height is taller than average, forced expiratory flow curve index were increased, there was a close relationship between height and forced expiratory flow curve, and there was a linear relationship as sector between height and forced expiratory flow curve index. Therefore, researches that study other factors such as sex, age, weight, body surface area, and obesity indexes other than height should be done to see if there are any further relationships.

• Asian Pacific Journal of Cancer Prevention
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• 제14권3호
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• pp.1721-1724
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• 2013

Objective: To investigate the effect of epirubicin on soluble CD25 (sCD25) secretion by CD4+CD25+ regulatory T (Treg) cells isolated from diffuse large B-cell lymphoma (DLBCL) patients. Methods: Treg cells were isolated from the peripheral blood mononuclear cells isolated from the newly diagnosed DBLCL patients. The concentration of sCD25 in the supernatant was determined with a commercial sCD25 (IL-2R) enzyme-linked immunosorbent assay (ELISA) kit. The fluorescence intensity of CD25 was detected by flow cytometry. Results: Cell survival rate was significantly decreased along with the increase of epirubicin concentration after treatment for 24 h. There was also a significant difference in the concentration of sCD25 between the epirubicin group and the control group (P<0.01). A positive correlation between the Treg cells survival rate and the concentration of sCD25 was detected (r=0.993, P<0.01). When equal numbers of CD4+CD25+ Treg cells of the epirubicin group and the control group were cultured for another 24 h without epirubicin the CD25 fluorescence intensity on the surface of Treg cells was obviously higher in the epirubicin group than that in the control group (P<0.01), while the sCD25 concentration in the supernatant in the epirubicin group was significantly lower than that in the control group (P<0.05). Conclusion: Epirubicin may improve the body's immune functions by inhibiting the sCD25 secretion by Treg cells in DLBCL patients.

• 한국안광학회지
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• 제13권1호
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• pp.107-112
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• 2008

목적: 이 논문은 야간근시를 자각적굴절검사와 타각적굴절검사로 측정하여 두 검사방법간의 상관관계를 분석하고 야간근시와 동공의 크기 그리고 교정굴절력과의 관계를 알아보고자 하였다. 방법: 성인 164안(19세에서 44세까지 남성 44명, 여성 38명)을 대상으로 밝은 곳에서 자각적굴절검사와 타각적굴절검사로 검사하고 어두운 곳에서 다시 자각적굴절검사와 타각적굴절검사로 야간근시량을 측정하고 동공의 크기도 측정하였다. 통계분석은 SPSS (Statistical Package for the Social Science)를 이용하여 검증하였다. 결과: 나이가 적을수록 자각적굴절검사 $x^2$값 =219.48(p<0.01)와 타각적굴절검사 $x^2$값=241.98(p<0.01)에서 측정된 야간근시량이 높았고 동공의 크기도 크고 $x^2$값=151.74(p<0.01), 모두 상관성이 높게 나타났다. 어두운 곳에서 동공크기가 클수록 타각적굴절검사에서 측정된 야간 근시량이 증가하였고, $x^2$값=84.27(p<0.01)로 높은 상관성이 있었으나 자각적굴절검사에서는 상관성이 적었다. 자각적굴절검사로 측정된 야간근시량은 남성에서 평균 0.96${\pm}$0.4584D를 중심으로 ${\pm}$0.25D 범위에서 64안으로 전체 88안중 73%가 분포하였고, 여성에서도 평균 1.01${\pm}$0.4509D를 중심으로 ${\pm}$0.25D 범위에서 49안으로 전체 76안중 64%가 분포하였다. 타각적굴절검사에서는 남성평균 0.85${\pm}$0.4651D를 중심으로 ${\pm}$0.25D 범위에서 42안으로 전체 88안 중 48%가 분포하였고 여성에서도 평균 0.96${\pm}$0.4133D를 중심으로 ${\pm}$0.25D 범위에서 54안으로 전체 76안중 71%가 분포하였다. 자각적굴절검사와 타각적굴절검사로 측정된 야간근시량은 $x^2$값=265.35(p<0.01)로 높은 상관성이 있는 것으로 조사되었다. 결론: 두 검사 간에 상관성이 높아 자각적굴절검사만으로 측정한 야간근시값을 야간근시 교정용으로 활용할 수 있을 것으로 보여 진다.