• Journal of the Korea Convergence Society
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• v.8 no.10
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• pp.273-279
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• 2017

Purpose: This study was conducted to identify factors associated with cataract and age-related macular degeneration in elders. Methods: In total, 341,588 men(44.18%,) and women(61.887%), aged over 60, were recruited from Korean National Health Insurance Service-Senior(2002-2013). We also analysed the factors which determine the prevalence of contract (ICD-10: H25) and age-related macular degeneration(ICD-10: H353) using Cox proportional hazard regression model Results: The subjects who were women, in older age, the group of higher income level, with hypertension, with heart disease, and with diabetes, the prevalence of both contract and age-related macular were increased(p<0.0001). Conclusion: The prevalence of contract and age-related macular degeneration were higher in old age of Korean who has chronic diseases such as hypertension, heart disease, and diabetes. The management of chronic diseases are essentially required in elderly for more healthy eye in aged society.

• 건강소식
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• v.29 no.11 s.324
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• pp.22-23
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• 2005

• Proceedings of the Korea Information Processing Society Conference
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• 2021.05a
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• pp.401-403
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• 2021

본 시스템은 같은 환자로부터 촬영한 기존 안저영상과 초광각 안저영상을 Paired Dataset으로 지니고 있으며, 영상의 크기 및 해상도를 똑같이 맞추고, 황반부와 신경유두 및 혈관의 위치를 미세조정하는 과정을 자동화하는 것을 목표로 하고 있다. 이 과정은 황반부를 중심으로 하여 영상을 잘라내어 이미지의 크기를 맞추는 과정(Scaling)과, 황반부를 중심으로 잘라낸 한 쌍의 영상을 포개었을 때 황반부, 신경 유두, 혈관 등의 위치가 동일하도록 미세조정하는 과정(Warping)이 있다. Scaling Stage에선 기존 안저영상과 초광각 안저영상의 촬영범위가 현저하게 차이나기 때문에, 황반변성 부위를 잘 나타내도록 사전에 잘라낼 필요가 있으며, 이를 신경유두의 Object Detection을 활용할 예정이다. Warping Stage에선 동일한 위치에 같은 황반변성 정보가 내포되어야 하므로 규격조정 및 위치조정 과정이 필수적이며, 이후 안저영상 내의 특징들을 매칭하는 작업을 하기 위해 회전, 회절, 변환 작업 등이 이루어지며, 이는 Homography Estimation을 통하여 이미지 변환 matrix를 구하는 방법으로 진행된다. 자동조정된 안저영상 데이터는 추후에 GAN을 이용한 안저영상 생성모델을 위한 학습데이터로 이용할 예정이며, 현재로선 2500쌍의 데이터를 대상으로 실험을 진행중이지만, 최종적으로 3만 쌍의 안저영상 데이터를 목표로 하고 있다.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.11a
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• pp.43-45
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• 2022

본 논문은 황반변성 진단 모델 개발을 위해 안저 사진을 이용한 MobileNet2 전이학습 모델 개발과 안정적인 모델 성능을 위한 이미지 증강 방법 및 모델 성능 향상을 위한 파라미터 조정 방법을 제안한다. 보유하고 있는 이미지의 수가 매우 적다고 하더라도 적절한 전이학습 모델을 사용하고 이미지 증강 시 증강 방법과 증강한 이미지와 정상 이미지와의 비율을 적절히 고려할 경우 충분히 안정적인 결과를 얻어낼 수 있다. 또한 파라미터 조정을 통해서 성능 향상을 도모할 수 있다

• Research in Community and Public Health Nursing
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• v.24 no.1
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• pp.1-10
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• 2013

Purpose: This study was conducted to examine the degree of senile macular degeneration in elders aged 65 or older and identify factors associated with senile macular degeneration in elders within communities. Methods: Participants in this cross-sectional descriptive study were 388 elders without cataract, glaucoma, and diabetic retinopathy. Data were collected through face to face interviews using a questionnaire in an urban area from June 2010 to December 2011. To detect senile macular degeneration, the participants' self-tests were carried out with Amsler grid testing. Stepwise multivariate logistic regression was performed to evaluate the effects of health behavior and knowledge about eye health on senile macular degeneration. Results: The proportion of participants with senile macular degeneration was 11.6%. Factors that significantly increased the risk of senile macular degeneration included eye discomfort and history of ophthalmic examination (p<.05). Factors that significantly decreased the risk of senile macular degeneration included regular change of magnifiers, non-use of magnifiers, and knowledge about preventive effects of non-smoking and antioxidant vitamin intake on senile macular degeneration (p<.05). Conclusion: This study showed that programs for preventing senile macular degeneration were necessary for elders within communities and the results of this study can be used for developing those programs.

• Journal of Digital Convergence
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• v.19 no.10
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• pp.535-543
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• 2021

The aim of this study was to evaluate the correlation between senile eye diseases such as age-related macular degeneration (AMD), glaucoma and oral health behaviors. Data from the Seventh Korea National Health and Nutrition Examination Survey (KNHANES VII-2) were used to analyze oral health behaviors according to the presence of AMD and glaucoma. Demographics and oral behaviors were analyzed using the complex chi-square test and complex logistic regression to compare participants with AMD and glaucoma with those without AMD and glaucoma. According to the presence or absence of AMD and glaucoma, there were statistically significant differences in age, education level, oral care product use, and difficulty in speaking variables. The results of this study provide evidence of a significant association in some variables between oral behaviors and senile eye diseases.

• Journal of The Korean Ophthalmological Society
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• v.59 no.11
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• pp.1024-1029
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• 2018

Purpose: We examined aqueous humor levels of 25-hydroxyvitamin D (vitamin D) in patients with age-related macular degeneration to investigate possible relationships between aqueous humor vitamin D levels and clinical manifestations. Methods: Patients > 50 years of age, 52 eyes of 34 patients with age-related macular degeneration, and 23 eyes of 17 patients treated with cataract surgery without retinal disease, were examined for aqueous humor vitamin D levels and compared. The experimental group was divided into two groups according to the median value of aqueous humor vitamin D levels. We compared the clinical manifestations of macular degeneration in both groups and identified relationships between aqueous humor vitamin D levels and clinical features. Results: Vitamin D levels in the aqueous humor were significantly lower in the experimental group than in the control group (experimental, $10.03{\pm}10.1ng/mL$ vs. control group, $40.8{\pm}16.4ng/mL$; p < 0.001). Patients with high vitamin D levels in the macular degeneration group had a higher percentage of fibrovascular pigment epithelial detachments than those in the low grade group (high grade group, 65% vs. low grade group, 27%; p = 0.003). Multiple linear regression analysis showed a significant correlation between vitamin D levels and the total number of anti-vascular endothelial growth factor intravitreal injections within 6 months (standardize coefficient, ${\beta}=-0.336$). Conclusions: Patients with wet age-related macular degeneration had significantly lower vitamin D levels in the aqueous humor compared to control group subjects of similar ages. However, in patients with macular degeneration, low vitamin D levels were associated with a greater number of intravitreal injections, while higher levels of vitamin D may lead to more advanced forms of fibrovascular retinal pigment epithelium and related low vision. These relationships were not always constant, so further studies on the relationships between local vitamin D levels and ocular disorders are needed.

• The Korean Chronic Disease News
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• no.94
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• pp.6-7
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• 1988

중년 이후에는 대부분의 사람이 생리적인 노화현상의 일환으로 시력의 사용에 불편을 느끼게 되며 때로는 중년이후에 잘 발생하는 질환에 의하여, 심한 시력장애를 일으키는 수도 있다. 전자의 경우에는 노안, 비문증 등을 들 수 있고 후자의 경우는 백내장, 당뇨병성망막증, 망막정맥폐쇄증, 황반부 변성등을 들 수 있다.

• Journal of The Korean Ophthalmological Society
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• v.59 no.12
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• pp.1152-1159
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• 2018

Purpose: We prospectively investigated clinical changes and long-term outcomes after administration of the drugs recommended by the Age-Related Eye Disease Study-2 to patients with intermediate age-related macular degeneration (AMD). Methods: This prospective multicenter study enrolled 79 eyes of 55 patients taking lutein and zeaxanthin. The primary endpoint was contrast sensitivity; this was checked every 12 months for a total of 36 months after treatment commenced. The secondary endpoints were visual acuity, central macular thickness, and drusen volume; the latter two parameters were assessed using spectral domain optical coherence tomography. Results: The mean patient age was $72.46{\pm}7.16years$. Contrast sensitivity gradually improved at both three and six cycles per degree. The corrected visual acuity was $0.13{\pm}0.14logMAR$ and did not change significantly over the 36 months. Neither the central macular thickness nor drusen volume changed significantly. Conclusions: Contrast sensitivity markedly improved after treatment, improving vision and patient satisfaction. Visual acuity, central retinal thickness, and drusen volume did not deteriorate. Therefore, progression of AMD and visual function deterioration were halted.

• The Journal of Korean Medicine
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• v.21 no.4
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• pp.260-263
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• 2000

This case study was performed to investigate the effects of Chongsimyonja-tang and Dong's acupuncture therapy on senile macular degeneration patient who has been treated in the Dong-Eui oriental hospital. A 57-year-old female with senile macular degeneration complained of headaches, heaviness of the ache, night sweat, dizziness. For a duration of 2 months, We prescribed Chongsimyonja-tang, and added 3-4 herbs according to the symtoms and also treated the patient with Dong s acupuncture therapy. After 2 months, the patient's eyesight improved ($0.2{\rightarrow}0.7$) and the headaches disappeared, as did heaviness of the ache, night sweat, and dizziness. In this case Chongsimyonja-tang and Dong's acupuncture therapy present valuable treatment of senile macular degeneration.