• Proceedings of the Korean Institute of Industrial Safety Conference
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• 1997.11a
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• pp.267-270
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• 1997

악취 물질은 주로 정유공장, 분뇨 처리장, 축산$\cdot$수산 가공업, 화학공장 등에서 발생하며 작업장 내의 직원 뿐만 아니라 인근 지역주민들에게 정신적인 불쾌감을 주는 동시에 인체에 매우 유해한 물질들이다. 이들 악취의 주성분은 메틸머켑탄, 황화수소, 암모니아, 트리메틸아민 등의 물질이다. 이들 물질의 제거 방법에는 약액세정법, 직접연소법, 활성탄흡착법 등이 있다. 이중 활성탄 홉착법은 설비비와 운영경비상의 잇점으로 오랫동안 사용되어져 왔고, 현재도 악취가 많이 발생하는 사업장의 악취 제거 방법으로 널리 사용되고 있다. 그러나 기존의 활성탄을 이용한 흡착제거는 처리효율이 낮고, 이에 따른 흡착제의 충진량이 많아지고 시설용량이 커지는 등의 결점이 있다. 이러한 문제점을 해결하기 위해 활성탄의 성질의 개선과 ACF와 같은 흡착제의 활용등에 대한 연구들이 진행되고 있다. (중략)

• Microbiology and Biotechnology Letters
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• v.18 no.4
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• pp.331-337
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• 1990

An antitumor antibiotic named B-1123 substance was isolated from the culture filtrate of a new isolate fungus identified as Aspergillus terreus. The fermentation yield reached about 23 mg per liter of the broth. The B-1123 substance, chlorine containing antibiotic, has the molecular formular of $C_{17}H_{12}0_7C_{12}$. Its structure was determined to be geodin by spectroscopic data. It is active against some Gram-positive bacteria and it prolongs the life span of mice inoculated with Ehrlich carcinoma.

• Korean Journal of Plant Tissue Culture
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• v.24 no.3
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• pp.149-152
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• 1997

To search for a compound inhibiting the petunia callus growth from Streptomyces sp., we investigated the activity in the culture broth of 400 strains. The active compound was successively purified with solvent fractionation, silica gel column chromatography from Streptomyces sp. 9602 strain, and identified as 2, 5, 7-trihydroxy-3-(5'-hydroxyhexyl)-1, 4-naphthoquinone by 1H-NMR, EI-MS, IR and UV. It inhibited the callus growth of petunia by 50% at $32\mu\textrm{g}$/mL.

• Korean Journal Plant Pathology
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• v.12 no.1
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• pp.66-71
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• 1996

79종의 식물재료의 Alternaria alternata에 대한 항균활성을 조사한 결과, 7가지 식물재료가 항균활성이 있었고, 11가지는 확실치 않았으며, 나머지 61가지는 항균활성이 나타나지 않았다. A. alternata에 항균활성이 나타난 7가지 식물재료 중 계피가 활성이 가장 높았으며, 오미지와 천궁이 중정도의 활성을 보였으며, 나머지는 약한 활성을 나타내었다. 항균 활성 성분은 계피와 천궁의 경우는 diethyl ether에 분리되었고, 오미자의 경우는 butanol에 분리되었다. 계피의 diethyl ether 추출물은 1,000 배액 이하에서 식별 가능한 항균활성이 나타났다. 계피의 성분으로 cinnam aldehyde가 가장 높은 활성을 보여, 이 물질이 계피의 주요 항균물질로 사료된다.

• Journal of Korean Society of Environmental Engineers
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• v.30 no.9
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• pp.925-932
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• 2008

Adsorption performance of tetracycline antibiotic compounds such as tetracycline(TC), oxytetracycline(OTC), chlortetracycline (CTC) and minocycline(MNC) on granular activated carbon(GAC) was evaluated in this study. The coal-based activated carbon was found to be more effective than other carbons in adsorption of tetracycline antibiotic compounds. The wood-based activated carbon was less effective than coconut- and coal-based carbon in adsorption nevertheless having larger pore volume and specific surface area than others carbons. The maximum adsorption capacities(X/M) of coal-based activated carbon for the four tetracycline species was 1.27$\sim$1.36 and 1.69$\sim$1.84 times larger than coconut- and wood-based activated carbon, respectively. Carbon usage rates(CUR) of coal-, coconut- and wood-based activated carbons for tetracycline(TC) were 2.96 g/day, 3.40 g/day and 4.53 g/day, respectively. Similar results were obtained in the adsorption of the rest three tetracycline species. It is concluded that coal-based activated carbon could removed the tetracycline antibiotic compounds better than other material-based activated carbons.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 1975.12a
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• pp.183.1-183
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• 1975

전보에서 는 Streptomyces속 균주가 생성하는 살어성물상의 작용에 對해서 發表하였다. 본보에서는 이 물질을 생성하는 균주가 Streptomyces umbrosus로 동정하였으며 본 물질은 정제와 아울러 이 균주가 유효물질을 생성하는데 영향을 미치는 영양물질을 조사하여 그 생성기구를 추정하였으며 어류에 미치는 작용을 조직학적으로 조사한 바를 발표코저 한다.

• Microbiology and Biotechnology Letters
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• v.19 no.3
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• pp.235-241
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• 1991

- A phthalic acid derivative and basic macrolide antibiotics, with antimicrobial activity against Gram positive bacteria and phytopathogenic fungi, respectively, were found to be produced by a strain 88-GT-161 identified as being a variety of Streptomyces melanosporofaciens. This paper describes an isolation procedure of the active compounds produced by this strain, their in vitro and in vivo (pot test) antimicrobial activites, and structure determination of one of the compounds, bis (2-ethylhexyl) phthalate, a phthalic acid derivative antibiotic. This compounds, upon cornparision with authentic bis (2-ethylhexyl) phthalate, dioctyl phthalate, revealed a difference in antimicrobial activity even though physico-chemical properties of these two compounds seemed indentical. This is the first report that dioctyl phthalate is biosynthetically produced by a Streptomyces sp. and shows antimicrobial activity.

• Korean Journal Plant Pathology
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• v.11 no.2
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• pp.158-164
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• 1995

토마토의 엽권에서 분리한 Fusariym graminearum이 분비하는 물질은 벼 도열병균(Pyricularia oryzae)의 여러 종의 식물병원 진균에 대한 항균활성을 나타내었으며, 이러한 활성물질을 PDA에서 본 균을 배양 한 후 chloroform으로 추출하여 분리정제 하였다. HPLC에 의하여 5종류의 활성 물질을 분획하였으며, 그중 1번(F402) 화합물을 벼 도열병균(P. oryzae)을 포함한 22개 식물 병원 진균에 대하여 살균 활성범위를 조사한 결과, 이 화합물은 50$\mu\textrm{g}$/ml 농도에서 Pythium ultimum, Rhizoctonia solani, Sclerotinia sclerotiorum은 전혀 억제하지 못하였으며, Phytophthora spp., Cladosporium fulvum, Fusarium spp., Corynespora cassicola에는 어느 정도의 활성이 있었지만 낮게 나타났고, P. oryzae, Cochliobolus miyabeanus, Alternaria solani는 100% 억제하여 활성이 높게 나타났다. 또한 장내 세균에 대한 활성을 MIC로 비교할 때 Streptococcus pyogenes, Streptococcus faecium에 대하여는 각각 12.5, 25 $\mu\textrm{g}$/ml였고 Staphylococcus aureus는 25-50$\mu\textrm{g}$/ml으로 나타났으며, Pseudomonas aeruginosa, Salmonella typhimurium, Klebsiella aerogenes, Enterobacter cloacae에서는 100$\mu\textrm{g}$/ml 이상으로 활성이 나타나지 않았다. F402를 200$\mu\textrm{g}$/ml의 농도로 직접 살포한 식물체에서의 방제효과는 벼도열병, 벼 깨씨무늬병, 보리 흰 가루병에 대하여는 80%이상이었으나, 벼 잎집무늬마름병, 오이 잿빛곰팡이병, 토마토 역병, 밀 녹병에서는 낮았다.

• Microbiology and Biotechnology Letters
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• v.21 no.1
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• pp.59-65
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• 1993

We isolated Actinomycetes strain GMT 1155 and purified the active compound, MT 1155, on the morphological reversion of ts/NRK cell from the isolate. MT 1155 was identified as toyocamycin having antifungal and antitumor activities from physico-chemical properties and UV, IR, $^1H$-NMR, $^13C$-NMR and mass spectrum. MT 1155 showed the morphologically reversional activity on ts/NRK cell and the cytotoxicity on CTLL cell at the final concentrations of 1.7 JlM and 0.2 11M, respectively and its $IC_{50}$ value on protein kinase A enzyme was 2.3 $\mu$M. Also it had strong antifungal activity against several pathogenic fungi but not antibacterial activity. And it did not inhibit both protein kinase C activity and the bleb-formation of K562 cell induced by phorbol esters.

• Journal of the Korean Society for Marine Environment & Energy
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• v.11 no.4
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• pp.214-220
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• 2008

The Ballast Water Management Convention provides that ballast water treatment systems which make use of active substances shall be approved from IMO according to the procedure developed by the IMO. The Convention described that active substance means a substance or organism, including a virus or a fungus, that has a general or specific action on or against harmful aquatic organisms and pathogens. The Marine Environment Protection Committee of IMO gave basic approval to 13 ballast water management systems and final approval to 4 systems until October 2008. This paper considered the matter of procedure and documents of the basic and final approval based on the "Procedure for approval of ballast water management systems that make use of Active Substances (G9)" and "The Methodology for information gathering and the conduct of work of the GESAMP-BWWG" and summarized the specifications of the treatment systems which was granted the basic or final approval from IMO and raised several points.