• Title/Summary/Keyword: 확산강조 자기공명영상

Search Result 88, Processing Time 0.031 seconds

High b-value Diffusion Study of Normal Brain at 3 Tesla

  • 이영주;손철호;황문정;배성진;장용민
    • Proceedings of the KSMRM Conference
    • /
    • 2002.11a
    • /
    • pp.83-83
    • /
    • 2002
  • 목적: 현재 임상적으로 사용되고 있는 확산경사자장의 세기 이상( > 1200)의 강한 확산 경사자장이 가해진 경우 뇌구조물들의 확산계수값을 조사하고 고자장(Bo = 3T)에서 이러한 강한 확산 경사자장을 이용하는 경우 1.5T에서 시행하는 경우와의 차이점을 비교 연구해보고자 하였다. 대상 및 방법: 정상 성인 3명을 대상으로 b-value를 0부터 3500까지 변화시키며 확산강조영상을 최대경사자장 40 mT/m, slew rate 150 T/m/s의 경사자장계가 장착된 3T MR scanner (General Electric, USA)에서 획득하였다. 사용한 펄스열은 Stejskal-Tanner type의 확산강조 경사자장이 포함된 single-shot SE EPI를 사용하였으며 영상획득시 사용한 파라미터는 다음과 같다. TR/TE= 10000/95.1, Thickness/space=512mm, FOV=24$\times$21cm, Matrix=128$\times$128, NEX=1 뇌구조물들에 관심 영역을 설정하고 b-value에 따른 신호감소를 측정하였다. 측정된 데이터를 hi-exponential decay 모델을 이용하여 분석하였다.

  • PDF

Diagnostic Performance of Simulated Abbreviated MRI for Early-Stage Hepatocellular Carcinoma Screening: A Comparison to Conventional Dynamic Contrast-Enhanced MRI (초기 간암 선별 검사로서 단축 자기공명영상 검사의 진단능: 고식적 역동학적 자기공명영상검사와의 비교)

  • Eun Sol Lim;Sung Mo Kim;Sang Soo Shin;Suk Hee Heo;Jong Eun Lee;Yong Yeon Jeong
    • Journal of the Korean Society of Radiology
    • /
    • v.82 no.5
    • /
    • pp.1218-1230
    • /
    • 2021
  • Purpose To compare the per-patient diagnostic performance of simulated abbreviated MRI (AMRI) to that of conventional MRI (CMRI) with full-sequence dynamic gadoxetic acid (GA) enhancement for early-stage hepatocellular carcinoma (HCC) screening in high-risk patients. Materials and Methods A total of 201 consecutive patients at high-risk for HCC, who underwent 3T liver MRI, were included in this retrospective study. The AMRI protocol comprised T2-weighted imaging, hepatobiliary phase imaging after GA injection, and diffusion-weighted imaging. For each patient, two AMRI and CMRI image sets were independently reviewed by two radiologists. Inter-reader agreement was assessed using Cohen's kappa value. A composite reference standard was used to determine the diagnostic performance of each image set for each reader. Results A total of 93 HCCs were detected in 79 patients. The inter-reader agreement was almost perfect for both image sets (κ = 0.839, 0.948). In AMRI, the per-patient sensitivity and negative predictive values (NPV) were 94.9% and 96.4%, respectively. In CMRI, the per-patient sensitivity and NPV were 96.2% and 97.5%, respectively. Conclusion AMRI, using only three sequences, had a comparable diagnostic performance to CMRI in screening early-stage HCC. AMRI could be an alternative HCC screening tool for high-risk HCC patients.

Role of MRI in Diagnostic Evaluation of Papillary Lesions of the Breast (유방의 유두상 병변의 진단에서 자기공명영상의 역할)

  • Lee, So-Mi;Kim, Hye-Jung;Gwak, Yeon-Joo;Lee, Hui-Joong;Jang, Yun-Jin;Shin, Kyung-Min;Park, Ji-Young;Jung, Jin-Hyang
    • Investigative Magnetic Resonance Imaging
    • /
    • v.14 no.1
    • /
    • pp.41-46
    • /
    • 2010
  • Purpose : To evaluate the role of magnetic resonance imaging (MRI) in the diagnosis of papillary lesions of the breast. Materials and methods : Among 45 papillary lesions diagnosed at ultrasonography-guided core biopsy (USCB), 27 benign papillary lesions in 22 patients who underwent breast MRI were reviewed. The excsional biopsy was performed in 1-10 days after MRI was done. In MRI findings, lesions were considered suspicious if they show irregular, rim enhancement, or linear enhancement in morphologic evaluation, or washout enhancement pattern of delayed phase in dynamic enhancement characteristics. Diffusionweighted images were analyzed according to visibility of lesions. MRI findings were correlated with pathologic results at excisional biopsy. Results : At excisional biopsy, two lesions (9%) were diagnosed malignant in 22 benign papillary lesions without atypia by USCB and 4 (80%) were malignant in 5 benign papillary lesions with atypia by USCB. Among 18 lesions detected on MRI, 16 lesions showed suspicious findings on MRI, 11 lesions (69%) were diagnosed as benign and 5 (31%) were malignant. Among 12 lesions detected on diffusion weighted imaging, 10 lesions were diagnosed as benign and 2 were malignant. MRI findings were not significantly correlated with pathologic results at excisional biopsy. Conclusion : MRI findings were not useful to predict malignancy in benign papillary lesions diagnosed at USCB, because MRI findings of these were mostly suspicious (88.9%, 16/18). The benign papillary lesion should be included in the false positive lesion on breast MRI.

Quantitative, qualitative Evaluation of Diffusion-Weighted MRI using Optimal b-value(s/mm2) for Female Pelvis (여성골반에 대한 최적의 b-value(s/mm2)를 이용한 확산강조 자기공명영상의 정량적, 성적 평가)

  • Goo, Eun-Hoe
    • Journal of Digital Convergence
    • /
    • v.11 no.1
    • /
    • pp.361-368
    • /
    • 2013
  • The purpose of this study is to know the clinical usefulness of optimal b-values by quantitative, qualitative evaluation of DW-MRI for lesions of benignity and malignity of female pelvis. The b-values used in DWI were 600, 800, 1000, 1200, 1400($s/mm^2$). Mean SNR and CNR of myoma in b-value 800 were the highest result as $84.6{\pm}4.57$(p=0.024) and $50.13{\pm}5.47$(p=0.028), Mean SNR and CNR of cervical cancer were the highest result as $12.0{\pm}2.04$(p=0.047) and $10.6{\pm}1.24$(p=0.001), Mean ADC value in myoma and cervical cancer in b-value 800 were $1.19{\times}10^{-3}mm^2/s$(p=0.008), $0.96{\times}10^{-3}mm^2/s$(p=0.027). As a qualitative analysis, the delineation and conspicuity were the highest result as $4.02{\pm}0.18$(p=0.028), $4.39{\pm}0.25$(p=0.015) on b-value 800. DW-MRI is an important method, and the optimal b values is 800 $s/mm^2$ for differentiation between benign and malignant lesions of female pelvis.

Diffusion Weighted MR Imaging of Spinal Cord: Preliminary Report

  • 인연권;이승구;김상흠;김시연;김동익
    • Proceedings of the KSMRM Conference
    • /
    • 2001.11a
    • /
    • pp.166-166
    • /
    • 2001
  • 목적: 척수의 질환에 대한 확산강조영상 소견에 대하여 알아본다. 대상 및 방법: 임상적으로 진단된 척수질환 환자 8명을 (acute transverse myelitis (n=3), spinal dural AV fistula (n=2), multiple sclerosis (n=1), spinal cord tumor (n=2)) 대상으로 하였다. 영상은 Philips Intera 1.5 T system을 이용하였고, multishot spin echo EPI 펄스열 및 EKG gating을 이용하여 영상을 얻었다. 3R-R 간격으로 영상을 얻었으며 TE=72msec, FOV=25cm, 256 matrix, 5mm thickness, b value=400으로 영상매개변수를 정하였다. 척수 중심으로 3개의 절편을 얻었으며 T2 강조 영상과 겉보기확산계수 영상을 같이 구하였다.

  • PDF

Usefulness of High-B-value Diffusion - Weighted MR Imaging for the Pre-operative Detection of Rectal Cancers (B-values 변환 자기공명영상: 국소 직장암 수술 전 검출을 위한 적합한 b-value 유용성)

  • Lee, Jae-Seung;Goo, Eun-Hoe;Lee, Sun-Yeob;Park, Cheol-Soo;Choi, Ji-Won
    • The Journal of the Korea Contents Association
    • /
    • v.9 no.12
    • /
    • pp.683-690
    • /
    • 2009
  • The purpose of this study is to evaluate the usefulness of high-b-values diffusion weighted magnetic resonance imaging for the preoperative detection of focal rectum cancers. 60patients with diffusion weighted imaging were evaluated for the presence of rectal cancers. Forty were male and twenty were female, and their ages ranged from 38 to 71 (mean, 56) years. Used equipment was 1.5Tesla MRI((GE, General Electric Medical System, Excite HD). Examination protocols were used the fast spin echo T2, T1 weighted imaging. All examination protocols were performed by the same location with diffusion weighted imaging for accuracy detection. The b-values used in DWI were 250, 500, 750, 1000. 1500, 2000$(s/mm^2)$. The rectum, bladder to tumor contrast-to-noise ratio (CNR) of MR images were quantitativlely analyzed using GE software Functool tool, four experienced radiologists and three radiotechnologists qualitatively evaluated image quality in terms of image artifacts, lesion conspicuity and rectal wall. These data were analysed by using ANOVA and Freedman test with each b-value(p<0.05). Contrast to noise ratio of rectum, bladder and tumor in b-value 1000 were 27.21, 24.44, respectively(p<0.05) and aADC value was $0.73\times10^{-3}$. As a qualitative analysis, the conspicuity and discrimination from the rectal wall of lesions were high results as $4.0\pm0.14$, $4.4\pm0.16$ on b-value 1000(p<0.05), image artifacts were high results as $4.8\pm0.25$ on b-value 2000(p<0.05). In conclusion, DWI was provided useful information with depicting the pre-operative detection of rectal cancers, High-b-value 1000 image was the most excellent DWI value.

Tumor Margin Infiltration in Soft Tissue Sarcomas: Prediction Using 3T MRI Texture Analysis (연조직 육종의 종양 가장자리 침윤: 3T 자기공명영상 텍스처 분석을 통한 예측)

  • Minji Kim;Won-Hee Jee;Youngjun Lee;Ji Hyun Hong;Chan Kwon Jung;Yang-Guk Chung;So-Yeon Lee
    • Journal of the Korean Society of Radiology
    • /
    • v.83 no.1
    • /
    • pp.112-126
    • /
    • 2022
  • Purpose To determine the value of 3 Tesla (T) MRI texture analysis for predicting tumor margin infiltration in soft tissue sarcomas. Materials and Methods Thirty-one patients who underwent 3T MRI and had a pathologically confirmed diagnosis of soft tissue sarcoma were included in this study. Margin infiltration on pathology was used as the gold standard. Texture analysis of soft tissue sarcomas was performed on axial T1-weighted images (WI) and T2WI, fat-suppressed contrast-enhanced (CE) T1WI, diffusion-weighted images (DWI) with b-value of 800 s/mm2, and apparent diffusion coefficient (ADC) was mapped. Quantitative parameters were compared between sarcomas with infiltrative margins and those with circumscribed margins. Results Among the 31 patients with soft tissue sarcomas, 23 showed tumor margin infiltration on pathology. There were significant differences in kurtosis with the spatial scaling factor (SSF) of 0 and 6 on T1WI, kurtosis (SSF, 0) on CE-T1WI, skewness (SSF, 0) on DWI, and skewness (SSF, 2, 4) on ADC between sarcomas with infiltrative margins and those with circumscribed margins (p ≤ 0.046). The area under the receiver operating characteristic curve based on MR texture features for identification of infiltrative tumor margins was 0.951 (p < 0.001). Conclusion MR texture analysis is reliable and accurate for the prediction of infiltrative margins of soft tissue sarcomas.

In Vitro imaging of MRI and Ultrasound for Colorectal Carcinoma (직결장암 조직의 자기공명영상과 초음파 소견에 대한 비교 연구)

  • Lee, Hwang Kyu;Jee, Keum Nahn;Hong, Sujin;Koh, Jae Hyang
    • Investigative Magnetic Resonance Imaging
    • /
    • v.17 no.2
    • /
    • pp.133-143
    • /
    • 2013
  • Purpose : To evaluate and compare the accuracy of magnetic resonance imaging (MRI) and ultrasound (US) for detection and estimation of invasion depth of colorectal carcinoma (CRC) by correlation with histopathologic findings in vitro, and to find out the best MR pulse sequence for accurate delineation of tumor from surrounding normal tissue. Materials and Methods: Resected specimens of CRC from 45 patients were examined about tumor detectability and invasion depth of US using high frequency (5-17 MHz) linear transducer in a tube filled with normal saline and MRI in a 8-channel quadrate head coil. The institutional review board approved this study and informed consent was waived. MRI with seven pulse sequences of in- and out-of-phases gradient echo T1 weighted images, fast spin echo T2 weighted image and its fat suppression image, fast imaging employing steady-state acquisition (FIESTA) and its fat suppression image, and diffusion weighted image (DWI) were performed. In each case, both imaging findings of MRI and US were evaluated independently for detection and estimation of invasion depth of tumor by consensus of two radiologists and were compared about diagnostic accuracy according to the histopathologic findings as reference standard. Seven MR pulse sequences were evaluated on the point of accurate delineation of tumor from surrounding normal tissue in each specimen. Results: In specimens of CRC, both imaging modalities of MRI (91.1%) and US (86.7%) showed relatively high diagnostic accuracy to detect tumor and evaluate invasion depth of tumor. In early CRC, diagnostic accuracy of US was 87.5% and that of MRI was 75.0%. There was no statistically significant difference between two imaging modalities (p > 0.05). The best pulse sequence among seven MR sequences for accurate delineation of tumor from surrounding normal tissue in each specimen of CRC was fast spin echo T2 weighted image. Conclusion: MRI and US show relatively high diagnostic accuracy to detect tumor and evaluate invasion depth of resected specimen of CRC. The most excellent pulse sequence of MRI for accurate delineation of tumor from surrounding normal tissue in CRC is fast spin echo T2 weighted image.