• Title/Summary/Keyword: 확률적 분석

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The Prevalence of Obesity and Metabolic Abnormalities in Korean Pediatric Population (한국 소아 청소년에서 비만 및 대사 이상의 유병률)

  • Nho, Han-Nae;Kim, Cu-Rie;Uhm, Ji-Hyun;Kim, Jeong-Tae;Jin, Sun-Mi;Seo, Ji-Young;Hahn, Hye-Won;Park, Hwa-Young;Yoon, Hye-Sun;Ahn, Young-Min;Shon, Keun-Chan
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.12 no.2
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    • pp.207-214
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    • 2009
  • Purpose: Childhood obesity can be complicated by hypertension, hyperlipidemia, non-alcoholic fatty liver disease, and diabetes mellitus. The aim of this study was to evaluate the prevalence of obesity and metabolic complications of children and adolescents based on the degree of obesity. Methods: We analyzed the records of 8,880 students who received student health examinations between May 2006 and October 2008 at the Eulji General Hospital. The prevalence of obesity was evaluated by the body mass index and obesity index. A total of 1,076 obese students had blood tests. We analyzed aspartate aminotransferase (AST), alanine aminotransferase (ALT), fasting glucose, total cholesterol, and blood pressure according to the degree of obesity. Results: According to the body mass index, the overall prevalence of obesity was 7.2% (7.8% of male and 6.5% of female students). Based on the obesity index, 12.3% of students (mild: 6.3%, moderate: 5.0%, and severe: 1.0%) were obese. The prevalence of hypercholesterolemia, ALT elevation, and hypertension were increased as a function of the degree of obesity (p<0.05), but hyperglycemia showed no significant differences (p=0.298). The overall prevalence of ALT elevation was 17.7% (mild obese group, 10.4%; moderate obese group, 20.5%; and severe obese group, 46.8%). The prevalence of hypercholesterolemia, hypertension, and hyperglycemia were significantly higher in the elevated ALT group (24.7%, 42.6%, and 5.2%, respectively) compared to the normal ALT group (11.1%, 29.8%, and 2.0%, respectively; p<0.05). Conclusion: Hypercholesterolemia, liver function test abnormalities, and hypertension were associated with the degree of obesity. We should focus our attention on managing obese children and adolescents to prevent metabolic complications.

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Variation of cyanobacteria occurrence pattern and environmental factors in Lake Juam (주암호 유해남조류 출현양상과 환경요인 변화)

  • Chung, Hyeonsu;Son, Misun;Ryu, Hui-Seong;Park, Chang Hee;Lee, Rury;Cho, Misun;Lim, Chaehong;Park, Jonghwan;Kim, Kyunghyun
    • Korean Journal of Environmental Biology
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    • v.37 no.4
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    • pp.640-651
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    • 2019
  • The study analyzed the relationship between harmful cyanobacteria and physicochemical factors in Lake Juam from 2005 to 2018. The research locations were designated St. 1 (Juam-Dam) and St. 2 (Sinpyong). Harmful cyanobacteria was found in four genera (Microcystis sp., Anabaena sp., Aphanizomenon sp., Oscillatoria sp.). The average standing crops of harmful cyanobacteria in both locations were 2,575 cells mL-1 and 2,557 cells mL-1 from 2005 to 2011. Since 2012, there has been a significant decrease that the measurements were 42 cells mL-1 and 82 cells mL-1 from 2012 to 2018. To analyze the reason for the decrease in harmful cyanobacteria, Pearson's correlation and t-tests were performed on data collected during the summer period (June-September). Pearson's correlation showed a significantly positive correlation with total nitrogen(TN), outflow, and storage and a negative correlation with electrical conductivity. T-tests were conducted in two different periods and showed decreases in total nitrogen, electrical conductivity, and residence time. The average rainfall was decreased from 263.3 mm (2005-2011) to 219.9 mm (2012-2018) and total nitrogen was decreased from 0.912 mg L-1 (2005-2011) to 0.811 mg L-1 (2012-2018) and the same variability was seen in TP (total phosphorus). Therefore, it seems that the low-rainfall decreased the nutrients (TN) and variability in the TP, resulting in a decrease in harmful cyanobacteria in Lake Juam.

Characteristics of the Maximum Glow Intensity According to the Thermoluminescent Phosphors used in the Absorbed Dose Measurement of the Radiation Therapy (방사선치료 선량 측정에 사용되는 열형광체에 따른 최대 형광 강도 특성)

  • Kang, Suman;Im, Inchul;Park, Cheolwoo;Lee, Mihyeon;Lee, Jaeseung
    • Journal of the Korean Society of Radiology
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    • v.8 no.4
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    • pp.181-187
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    • 2014
  • The purpose of this study were to analyze the characteristic of the glow curves in order to the glow temperature of the thermoluminescent dosimeters (TLDs) for the absorbed dose measurement of the radiation therapy. In this study, we was used the TLDs of the LiF:Mg${\cdot}$Ti, LiF:Mg${\cdot}$Cu${\cdot}$P, $CaF_2$:Dy, $CaF_2$:Mn (Thermo Fisher Scientific Inc., USA). The source-to-solid dry phantom (RW3 slab, IBA Dosmetry, Germany) surface distance was set at 100 cm, and the exposure dose of 100 MU (monitor unit) was used 6- and 15-MV X-rays, and 6- and 12-MeV electron beams in the reference depth, respectively. After the radiations exposure, we were to analyze the glow curves by using the TL reader (Hashaw 3500, Thermo Fisher Scientific Inc., USA) at the fixed heating rate of $15^{\circ}C/sec$ from $50^{\circ}C$ to $260^{\circ}C$. The glow peaks, the trapping level in the captured electrons and holes combined with the emitted light, were discovered the two or three peak. When the definite increasing the temperature of the TLDs, the maximum glow peak representing the glow temperature was follow as; $LiF:Mg{\cdot}Ti$: $185.5{\pm}1.3^{\circ}C$, $LiF:Mg{\cdot}Ti$: $135.0{\pm}5.1^{\circ}C$, $CaF_2$:Dy: $144.0{\pm}1.6^{\circ}C$, $CaF_2$:Mn: $294.3{\pm}3.8^{\circ}C$, respectively. Because the glow emission probability of the captured electrons depend on the heating temperature after the exposure radiation, TLDs by applying the fixed heating rate, the accuracy of measurement will be able to improve within the absorbed dose measurement of the radiation therapy.

Temperature Data-Based Assessment of the Marginal Heading Dates and the Growth Duration of Rice in the Regions of North Korea (북한 지역의 기온 자료를 활용한 벼 출수 한계기 및 재배 기간 분석)

  • Yang, Woonho;Kang, Shingu;Kim, Sukjin;Choi, Jong-Seo;Park, Jeong-Hwa
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.20 no.4
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    • pp.284-295
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    • 2018
  • The safe and late marginal heading dates (SMHD, LMHD), cropping probability, and growth duration of rice were assessed using temperature data in the 27 regions of North Korea. The medians of SMHD and LMHD ranged Jul. 16 and Jul. 27 in Hyesan to Aug. 18 and Aug. 28 in Haeju, respectively, except Changjin, Pungsan, and Samjiyon that did not show any of the SMHD and LMHD. The medians of the days from early marginal transplanting date (EMTD) to heading date ranged 51 days in Hyesan to 109 days in Pyongyang for SMHD and those were delayed by 9~15 days for LMHD, compared to SMHD. Nineteen regions (Kaesong, Haeju, Yongyon, Singye, Sariwon, Nampo, Pyongyang, Anju, Kusong, Sinuiju, Changjon, Wonsan, Hamhung, Pyonggang, Yangdok, Huichon, Supung, Sinpo, Kanggye) and additional four regions (Kimchaek, Chongjin, Sonbong, Chunggang) had the rice cropping probability higher than 80% when analyzed based on the SMHD and LMHD, respectively. The representative SMHD ranged Jul. 24 for Pyonggang to Aug. 12 for Haeju. Compared to the days from EMTD to SMHD, those from EMTD to LMHD were delayed by 9~17 days. When applied SMHD, thirteen regions (Yangdok, Kanggye, Huichon, Supung, Yongyon, Kusong, Anju, Sinuiju, Singye, Pyongyang, Kaesong, Nampo, Sariwon) had the appropriate range of cumulative temperature during grain filling (CT) for grain yield and quality. Sinpo, Hamhung, Pyonggang, Wonsan, Changjon, and Haeju had the CT higher than $1,300^{\circ}C$. It is supposed that rice cropping could be extended to the regions where LMHD-applied cropping probability was higher than 80%. Delaying the heading date than SMHD could be also considered in the regions where the days to SMHD is small but CT is large.

The Ontology Based, the Movie Contents Recommendation Scheme, Using Relations of Movie Metadata (온톨로지 기반 영화 메타데이터간 연관성을 활용한 영화 추천 기법)

  • Kim, Jaeyoung;Lee, Seok-Won
    • Journal of Intelligence and Information Systems
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    • v.19 no.3
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    • pp.25-44
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    • 2013
  • Accessing movie contents has become easier and increased with the advent of smart TV, IPTV and web services that are able to be used to search and watch movies. In this situation, there are increasing search for preference movie contents of users. However, since the amount of provided movie contents is too large, the user needs more effort and time for searching the movie contents. Hence, there are a lot of researches for recommendations of personalized item through analysis and clustering of the user preferences and user profiles. In this study, we propose recommendation system which uses ontology based knowledge base. Our ontology can represent not only relations between metadata of movies but also relations between metadata and profile of user. The relation of each metadata can show similarity between movies. In order to build, the knowledge base our ontology model is considered two aspects which are the movie metadata model and the user model. On the part of build the movie metadata model based on ontology, we decide main metadata that are genre, actor/actress, keywords and synopsis. Those affect that users choose the interested movie. And there are demographic information of user and relation between user and movie metadata in user model. In our model, movie ontology model consists of seven concepts (Movie, Genre, Keywords, Synopsis Keywords, Character, and Person), eight attributes (title, rating, limit, description, character name, character description, person job, person name) and ten relations between concepts. For our knowledge base, we input individual data of 14,374 movies for each concept in contents ontology model. This movie metadata knowledge base is used to search the movie that is related to interesting metadata of user. And it can search the similar movie through relations between concepts. We also propose the architecture for movie recommendation. The proposed architecture consists of four components. The first component search candidate movies based the demographic information of the user. In this component, we decide the group of users according to demographic information to recommend the movie for each group and define the rule to decide the group of users. We generate the query that be used to search the candidate movie for recommendation in this component. The second component search candidate movies based user preference. When users choose the movie, users consider metadata such as genre, actor/actress, synopsis, keywords. Users input their preference and then in this component, system search the movie based on users preferences. The proposed system can search the similar movie through relation between concepts, unlike existing movie recommendation systems. Each metadata of recommended candidate movies have weight that will be used for deciding recommendation order. The third component the merges results of first component and second component. In this step, we calculate the weight of movies using the weight value of metadata for each movie. Then we sort movies order by the weight value. The fourth component analyzes result of third component, and then it decides level of the contribution of metadata. And we apply contribution weight to metadata. Finally, we use the result of this step as recommendation for users. We test the usability of the proposed scheme by using web application. We implement that web application for experimental process by using JSP, Java Script and prot$\acute{e}$g$\acute{e}$ API. In our experiment, we collect results of 20 men and woman, ranging in age from 20 to 29. And we use 7,418 movies with rating that is not fewer than 7.0. In order to experiment, we provide Top-5, Top-10 and Top-20 recommended movies to user, and then users choose interested movies. The result of experiment is that average number of to choose interested movie are 2.1 in Top-5, 3.35 in Top-10, 6.35 in Top-20. It is better than results that are yielded by for each metadata.

Reproduction Cycle and Litter Size of Red-tongued viper snake (Gloydius ussuriensis) (쇠살모사의 생식주기와 한배의 출산수)

  • Kim, Byoung-Soo;Oh, Hong-Shik
    • Korean Journal of Environment and Ecology
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    • v.28 no.5
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    • pp.531-541
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    • 2014
  • This research investigated the reproduction cycle, litter size, and the effects of factors of red-tongue viper snake inhabiting in Jeju Island, to delve into their life strategy. Field survey was conducted in Jeju Island from May 2006 to November 2008. Reproduction cycle was analyzed through measurements of testis and follicle sizes in laboratory from March 2009 to December 2010. According to the research results, the sizes of red-tongue viper snake's testis and follicle clearly changed seasonally. The number of eggs within the oviduct were greater on the right side ($2.6{\pm}1.0$ eggs, n=16) than on the left side ($1.8{\pm}0.5$ eggs, n=16) (t=-2,721, p<0.05). Average (${\pm}SD$) of survival litter size (SLS) was $4.4{\pm}1.7$ (1~9, range), while total litter size (TLS) was $4.7{\pm}1.5$ (3~9, range), which were not statistically significant. However, their litter sizes were similar to the number of eggs within the oviduct (t=0.039, P>0.05). Relative litter mass (RCM) was $0.42{\pm}0.13$ (0.18~0.79, n=33), and tended to increase, as maternal condition of pre-parturition (MCPPI) was getting better. The sexual ratio of delivered litters showed no significant difference between male and female red-tongue viper snakes (♂:♀ = 1.15:1, n=73 ; ${\chi}^2$=0.342, P>0.5). Average neonate mass showed a weak correlation with maternal mass of pre-parturition (MMPP1) (r=0.387, P<0.05, n=33). Average neonate Snout-vent length (SVL) also demonstrated a weak correlations with maternal SVL (r=0.399, P<0.05, n=33) and MMPP1 (r=0.344, P<0.05, n=33). Average neonate mass and maternal SVL approached significant probability (r=0.323, P=0.067, n=33). This indicates that mother snakes can bear bigger litter due to its larger size. In some cases, litter's weight decreases as mother snakes are bearing more litter; however, the red-tongued viper snake did not show such exchange relationship. From this, it can be conjectured that a red-tongued viper snake has peculiarity of its own species. The research results are predicted to be used as the basis to find a life history of red-tongued viper snake.

Measurement of the Drifting Condition of the Anchovy Drift Gill Net with GPS (GPS에 의한 멸치 유자망의 표류상태측정규정)

  • 황중철
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.31 no.4
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    • pp.350-361
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    • 1995
  • For the Purpose of the measurement of drifting condition of the anchovy drift gill net, some experiments were carried out in M. S Seong-Yang at the near sea of Kampo harbor in Korean east sea from August to October 1994, by using three set of GPS equipped with her net. The main results obtained are as follows : 1) In fixed position by GPS at Taebyon, the radius of 95% probability and shifted distance from standard position were respectively 79.8m, 21.0m. 2) The mean values of PDOP and HDOP of GPS at Taebyon were respectively 3.5, 1.9 and the stability of the position by GPS at Taebyon was found to be very high. 3) In the fishing ground of the position from Lat. $35^{\circ}$ 41.5'N to $Lat^{\circ}$. 43.5', from Long. $129^{\circ}$ 32.0'E to Long. $129^{\circ}$ 32.5'E, the direction of the whole stretched drift gill net was $190^{\circ}$ and the direction of the whole casted net was $200^{\circ}$ when casting the net was finished. When whole net was found to be drifting into the direction of $170^{\circ}\;to\;180^{\circ}$, and the mean drifting speed of that was 0.82kt. 4) In the fishing ground of the position from Lat. $35^{\circ}$ 44.0'N to Lat. $35^{\circ}$ 45.2'N, from Long. $129^{\circ}$ 30.1'E to Long. $129^{\circ}$ 31.2'E, the direction of the whole stretched net was 20$^{\circ}$ and the direction of the whole stretched net was $20^{\circ}$ when casting the net was finished. When hauling the net, the direction of the spreaded net appeared from the North into the South and the whole net was found to be drifting into the direction of $210^{\circ}\;to\;220^{\circ}$, and the mean drifting speed of that was 0.75kt. 5) In the fishing ground of the positioning from Lat. $35^{\circ}$ 44.9'N to Lat. $35^{\circ}$ 46.0'N, Long. $129^{\circ}$ 33.0'E to Long. $129^{\circ}$ 34.0'E, the direction to the whole stretched net was $35^{\circ}$ and the direction of the whole casted net was $50^{\circ}$ when casting the net was finished. When hauling the net, the direction of the spreaded net appeared into the South from the East and the whole net was found to be drifting into the direction of $330^{\circ}\;to\;40^{\circ}$, and the mean drifting speed of the was 0.63kt.

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Development of the Multi-Parametric Mapping Software Based on Functional Maps to Determine the Clinical Target Volumes (임상표적체적 결정을 위한 기능 영상 기반 생물학적 인자 맵핑 소프트웨어 개발)

  • Park, Ji-Yeon;Jung, Won-Gyun;Lee, Jeong-Woo;Lee, Kyoung-Nam;Ahn, Kook-Jin;Hong, Se-Mie;Juh, Ra-Hyeong;Choe, Bo-Young;Suh, Tae-Suk
    • Progress in Medical Physics
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    • v.21 no.2
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    • pp.153-164
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    • 2010
  • To determine the clinical target volumes considering vascularity and cellularity of tumors, the software was developed for mapping of the analyzed biological clinical target volumes on anatomical images using regional cerebral blood volume (rCBV) maps and apparent diffusion coefficient (ADC) maps. The program provides the functions for integrated registrations using mutual information, affine transform and non-rigid registration. The registration accuracy is evaluated by the calculation of the overlapped ratio of segmented bone regions and average distance difference of contours between reference and registered images. The performance of the developed software was tested using multimodal images of a patient who has the residual tumor of high grade gliomas. Registration accuracy of about 74% and average 2.3 mm distance difference were calculated by the evaluation method of bone segmentation and contour extraction. The registration accuracy can be improved as higher as 4% by the manual adjustment functions. Advanced MR images are analyzed using color maps for rCBV maps and quantitative calculation based on region of interest (ROI) for ADC maps. Then, multi-parameters on the same voxels are plotted on plane and constitute the multi-functional parametric maps of which x and y axis representing rCBV and ADC values. According to the distributions of functional parameters, tumor regions showing the higher vascularity and cellularity are categorized according to the criteria corresponding malignant gliomas. Determined volumes reflecting pathological and physiological characteristics of tumors are marked on anatomical images. By applying the multi-functional images, errors arising from using one type of image would be reduced and local regions representing higher probability as tumor cells would be determined for radiation treatment plan. Biological tumor characteristics can be expressed using image registration and multi-functional parametric maps in the developed software. The software can be considered to delineate clinical target volumes using advanced MR images with anatomical images.

Clinical Experience of LINAC-based Stereotactic Radiosurgery for Angiographically Occult Vascular Malformations (혈관조영상 잠재혈관기형에 대한 선형가속기형 정위방사선수술의 임상경험)

  • Kim Dae Yong;Ahn Yong Chan;Lee Jung Il;Nam Do-Hyun;Lim Do Hoon;Lee Jeong Eun;Yeo Inhwan;Huh Seung Jae;Noh Young Joo;Shin Seong Soo;Hong Seung-Chyul;Kim Jong Hyun
    • Radiation Oncology Journal
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    • v.19 no.1
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    • pp.1-9
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    • 2001
  • Purpose : To establish the role of stereotactic radiosurgery (SRS) for the treatment of patients with angiographically occult vascular malformation (AOVM). Materials and Methods : Eleven patients (12 lesions) with AOVM were treated with linear accelerator-based SRS between February 1995 and December 1999. A magnetic resonance imaging of each patients showed well-circumscribed vascular lesion with reticulated core of heterogeneous signal intensity and peripheral rim of low signal intensity. SRS were peformed with the median peripheral dose of 16 Gy (range 13~25). A single isocenter was used with median collimator size of 14 mm (range 8~20) diameter. Results : With a median follow-up period of 42 months (range 12~56), rebleeding occurred in 3 AOVMS at 5, 6 and 12 months after SRS but no further bleeding did. Two patients experienced radiation-induced necrosis associated with permanent neurologic deficit and one patient showed transient edema of increased 72 signal intensity. Conclusion : SRS may be effective for the prevention of rebleeding in AOVM located in surgically inaccessible region of the brain. Careful consideration should be needed in the decision of case selection and dose prescription because the incidence of radiation-induced complications is too high to be accepted.

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Internal Mammary Lymph Node Irradiation after Breast Conservation Surgery: Radiation Pneumonitis versus Dose-Volume Histogram Parameters (유방보존술 후 내유림프절 방사선 조사: 방사선 폐렴과 체적-선량 히스토그램 변수들)

  • Kim, Joo-Young;Lee, Ik-Jae;Keum, Ki-Chang;Kim, Yong-Bae;Shim, Su-Jung;Jeong, Kyoung-Keun;Kim, Jong-Dae;Suh, Chang-Ok
    • Radiation Oncology Journal
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    • v.25 no.4
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    • pp.261-267
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    • 2007
  • Purpose: To evaluate the association between radiation pneumonitis and dose-volume histogram parameters and to provide practical guidelines to prevent radiation pneumonitis following radiotherapy administered for breast cancer including internal mammary lymph nodes. Materials and Methods: Twenty patients with early breast cancer who underwent a partial mastectomy were involved in this study. The entire breast, supraclavicular lymph nodes, and internal mammary lymph nodes were irradiated with a dose of 50.4 Gy in 28 fractions. Radiation pneumonitis was assessed by both radiological pulmonary change (RPC) and by evaluation of symptomatic radiation pneumonitis. Dose-volume histogram parameters were compared between patients with grade <2 RPC and those with grade ${\geq}$2 RPC. The parameters were the mean lung dose, V10 (percent lung volume receiving equal to and more than 10 Gy), V20, V30, V40, and normal tissue complication probability (NTCP). Results: Of the 20 patients, 9 (45%) developed grade 2 RPC and 11 (55%) did not develop RPC (grade 0). Only one patient developed grade 1 symptomatic radiation pneumonitis. Univariate analysis showed that among the dose-volume histogram parameters, NTCP was significantly different between the two RPC grade groups (p<0.05). Fisher's exact test indicated that an NTCP value of 45% was appropriate as an RPC threshold level. Conclusion: This study shows that NTCP can be used as a predictor of RPC after radiotherapy of the internal mammary lymph nodes in breast cancer. Clinically, it indicates that an RPC is likely to develop when the NTCP is greater than 45%.