• Journal of the Korean Crystal Growth and Crystal Technology
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• v.26 no.6
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• pp.243-251
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• 2016

Silanized-hydroxypropyl methylcellulose (Si-HPMC)/phase transformed calcium phosphate (PTCP) composites are prepared to purpose application of injectable bone cements with enhanced biocompatibility. The crystal structure and chemical state of the synthesized PTCP and Si-HPMC as solid and liquid phase of the composite cements were measured by XRD and FT-IR. The handling and mechanical properties of cements were measured by injectability tests and three-point bending tests. The in-vitro mechanical properties, XRD, and SEM results of bone cements were showed that enhanced hardening behavior was an inherent function of bone cements after in-vitro test. The cytotoxicity result of bone cements also was showed enhanced biocompatibility. Therefore, these injectable cements had potential be used as calcium phosphate cements for biomedical applications.

• Proceedings of the Korean Society of Toxicology Conference
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• 1997.10a
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• pp.38-42
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• 1997

Human growth hormone is known as one of the peptide hormones which is consisted of 191 amino acids derived from the pituitary gland in humans. The objectives of this study were to supply inexpensive recombinant methionyl human growth hormones (rHGH) synthesized by the DNA technology in a yeast cell line and followed by the establishement of protein purification techniques. The next steps of the research were to study its physic-chemical properties and biological properties, and to evaluate various preclinical aspcts including pharmacokinetics sutdy, general pharmacology study, general toxicity test, and specific toxicity tests. Clinical phase I, II, III studies were also done against growth hormone dficient children to reveal that growth promoting effects were similar compared with the natural HGH extracted from pituitary glands and commercially available rHGHs. The results could be summarized that (I) this yeast dervied rHGH have had excellent physico-chemical and biological properties in comparison with a natural HGH and other synthesized rHGHs, (2) we could not see any toxic side effects when very high doses were administered to the experimental animals, and (3) this growth hormone showed effectiveness in the growth stimulating to growth hormone deficient patients.

• Journal of the Korean Chemical Society
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• v.56 no.1
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• pp.144-158
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• 2012

In this study, science teachers' and students' perceptions were searched on lectures and experiment of law of definite proportion in middle school science classes. For this study, the three teachers' lessons were observed and recorded, following interviews related to teachers' perceptions on the lessons and experiments. Also, We analyzed students' science scores, cognitive levels, science attitude, experimental reports, etc. According to the results, the three teachers had different focuses in the lectures. Chemistry teachers accentuated calculation of proportions and application rather than basic conceptions. But the students could not understand basic conceptions properly. The teachers spend long time to explain experimental procedures by assuming a low performance level of students in experimental classes. And the teachers had negative perceptions about error of results. The students could not understand the experiment results well, tried to manipulate data artificially, and had negative perceptions about error of results like the teachers. We suggested that these problems might be solved by changing teachers' perceptions on school science lectures and experiments.

• Journal of the Korean Chemical Society
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• v.47 no.4
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• pp.391-400
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• 2003

This study was performed the analysis of seven kinds of the hight school chemistry II textbooks based on the 6th curriculum. Particularly, inquiry activity part was analyzed by the three dimension framework which consists of inquiry content dimension, inquiry process dimension and inquiry context dimension. In the analysis of the inquiry content dimension of inquiry activities, the total number of themes in seven kinds of textbook was 212. And the number of inquiry activities in seven kinds of textbook was diverse: A textbook had 28, B textbook 25, C textbook 31, D textbook 35, E textbook 31, F textbook 29 and G textbook 33. As for the avaerage number of inquiry activities of each chapter, chapter I "Material Science" is 3.00(9.91${\%}$), chapter II "Atomic Structure and Periodic Table" 4.57(15.1${\%}$), chapter III "Chemical Bonding and Compound" 6.86(22.6${\%}$), chapter IV "State of Matter and Solution" 7.00(23.1${\%}$), chapter V "Chemical Reaction" 8.86(29.2${\%}$). For the analysis of inquiry process dimension, it follows in the order of 'observation and measuring (66.7${\%}$)', 'Interpreting data and formulating generalizations (26.5${\%}$)', 'seeing a problem and seeking ways to solve it (4.1%)', and 'building, testing and revising the theoretical model (2.7${\%}$)'. As for the analysis of the inquiry context dimension, the scientific context occupied 90.5${\%}$, the individual context 4.3${\%}$, the social context 0.9${\%}$, and the technical context 4.3${\%}$. It shows that the proportion of STS(Science-Technology-Society) related contents in inquiry activities was only 9.5${\%}$.

• Journal of the Korean Chemical Society
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• v.66 no.4
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• pp.305-322
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• 2022

In this study, a practice-based teacher education program was developed and applied to improve the TPACK of pre-service chemistry teachers. Also the program effect and obstacles were confirmed by measuring the development of TPACK. The participants of this study were 20 pre-service chemistry teachers of 3rd grade and 2 pre-service chemistry teachers of 4th grade who took chemistry education courses at K University located in Chungcheongbuk Province. The developed teacher education program consisted of four stages: preparation, rehearsal, practice, and reflection. The feedbacks from researchers and colleagues pre-service teachers were provided in preparation, rehearsal, and reflection stages. As a result of the study, the program of this study did not show an educational effect in the "constructive learning activities" of preservice teachers, but it was found to have an educational effect in "problem solving". In other words, in "constructive learning activity", most pre-service teachers were at 0 level before and after the program. The pre-service teachers designed the class to unilaterally provide technology to simply use it as a tool to explain subject content or revise misconceptions, and learners can passively acquire knowledge. However, in the case of "problem solving", the pre-service teachers who were at level 0 before the educational program changed to level 1. Before the program, the pre-service teachers designed classes to solve problems by memory without using technology, but after the program they planned classes that provides opportunities to approach and solve various problems through the technology presented by the teacher. However, there were not many pre-service teachers corresponding to level 2, which constitutes voluntary learning in which learners use technology to solve various problems while selecting and variously manipulating technology. In addition, as obstacles to the TPACK development of pre-service chemistry teachers, there were external factors such as lack of classroom support environment for TPACK implementation, lack of time for education planning, and inadequate technology competency. And there were internal factors such as perspectives of traditional education and negative attitude toward technology. In particular, the proportion of pre-service teachers who preceived inappropriate technical competency as an external obstacles of TPACK development was high. Therefore, it was necessary to develop an education program corresponding to type 2 or type 3 that enables TPACK development through TK for pre-service teachers.

• Journal of the Korean Chemical Society
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• v.51 no.5
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• pp.423-432
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• 2007

In this study we investigated the types of inscriptions representing the concept of atom and molecule in the 9th grade science textbooks developed under the 7th National Curriculum, and analyzed the processes of interpreting those inscriptions on the view of semiotics. The concept of atom and molecule was represented in various ways such as circular diagram, matters of everyday life, ball-and-stick, and STM graphic, etc. We identified two kinds of inscriptions on the basis of the possibilities of handling models: the inscriptions that represent concept of atom and molecule by image; the inscriptions that represent concept of atom and molecule by using specific matters. We analyzed the processes of interpreting inscriptions systematically with a semiotic model that includes ‘structuring processes' and ‘translating processes'. The interpretation of inscriptions representing concept of atom and molecule was a complex process requiring many steps of interpreting works. Educational implications of these findings are discussed.

• Journal of the Korean Chemical Society
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• v.67 no.5
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• pp.378-392
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• 2023

The purpose of this study is to analyze the pre-service chemistry teachers' cognition of the nature of model in process of designing and developing models using technology. For this purpose, 19 pre-service chemistry teachers' in the 3rd grade of a education college located in the central region observe experimental phenomena related to Boyle's law presented in the 7th grade science textbook and researchers required the design and development of a model related to the observed experimental results using technology. Based on previous studies, the nature of model were classified into two aspect: 'Representational aspect' and 'Explanatory aspect'. The 'Representational aspect' was classified into 'Representation', 'Abstraction', and 'Simplification', and the 'Explanatory aspect' was classified into 'Analysis', 'Interpretation', 'Reasoning', 'Explanation', and 'Quantification'. The pre-service chemistry teachers' cognition were analyzed by the classification. As a result of the study, the 'Representation' of the 'expressive aspect' was uniformized in the form of space that changes in volume, and the pressure was expressed as the Brightness inside the cylinder or frequency of color change of particles for 'Abstraction'. In the case of 'Simplification', the particle collision was expressed as a perfectly elastic collision, but there was a group that could not simply indicate the type of particle. In the 'Explanatory aspect', in the case of 'Analysis', volume was classified as a manipulated variable, and in the case of 'Interpretation', most groups analyzed the change in pressure through the collision of gas particles. However, the cognition involved in 'Reasoning' was not observed much. In the case of 'Explanation', there were groups that did not succeed in explanation because the area where the particles collided was not set or incorrectly set, and in the case of 'Quantification', there was a group that formulated the number of collisions per unit time, and on the contrary, there was a group that could not quantify the number of collisions because they could not be expressed in numbers.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.15 no.4
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• pp.333-341
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• 2017

The Korea Atomic Energy Research Institute (KAERI) constructed the PyRoprocessing Integrated inactive Demonstration facility (PRIDE) to carry out experiments on engineering scale pyroprocessing. PRIDE has a large processing cell that human workers are not allowed to access, and thus the equipment inside is operated from outside using remote handling systems. It is therefore essential to examine the operability and maintainability of the equipment in view of remote handling systems, and the equipment is thoroughly examined in a mockup cell before it is installed in the processing cell. If the equipment is tested in a virtual mockup rather than in a mockup cell, the development cost can be significantly reduced. The PRIDE 3D simulator was integrated for virtual verification of equipment that will be installed in the processing cell. All remote handling devices in the actual PRIDE were also virtually installed in the PRIDE 3D simulator. The 3D model of the equipment was loaded and located in the exact position in the virtual processing cell. A scenario to replace an actual electrode was implemented in the PRIDE 3D simulator. The design of the equipment and the working procedures in the scenario were successfully evaluated. The results demonstrated that the PRIDE 3D simulator can be used successfully as an alternative to actual mockup testing.

• Korean Chemical Engineering Research
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• v.47 no.3
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• pp.368-372
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• 2009

A technique to measure the adsorption characteristic of surface area and pore size distribution is proposed and its performance is examined. While the existing equipment utilizes liquid nitrogen, the proposed uses carbon dioxide at the room temperature leading to the small measuring device with easy operation and short measurement time. The performance of the device has been examined with micro-particle carbon cryogel and bamboo activated carbon. The results from the proposed device compared with those of the adsorption apparatus indicate that the measurement of meso-porous material is comparable but micro-porous material gives some error.

• Korean Chemical Engineering Research
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• v.46 no.6
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• pp.1107-1112
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• 2008

Crystallization of calcium carbonate was performed by using aqueous calcium chloride and sodium carbonate for operational simplicity. Reaction time, solute concentrations, pH, and organic additive were varied to get calcium carbonate crystals. Silk fibroin was used as the additive to understand the change of morphology of calcium carbonate crystal. The crystals were analyzed by FE-SEM, XRD, and FT-IR. Reaction time, and pH mainly affected the morphology of crystals. Besides, it was found that silk fibroin inhibited the formation of vaterite and promoted the calcite forms.