• The Journal of the Acoustical Society of Korea
• /
• v.32 no.5
• /
• pp.430-437
• /
• 2013

The present study examined whether sentence perception scores were changed under various conditions of time alteration (compression and/or expansion) and selective word stress in normal hearing listeners. Twenty young normal hearing adults (ten males) were participated. As stimuli, Korean standard-sentence list for adults (KS-SL-A) modified to semantically anomalous sentences was newly recorded by a female speaker. Seven different time-altered conditions (e.g., ${\pm}60%$, ${\pm}40%$, ${\pm}20%$, 0 %) were controlled. To see the effect of selective word stress (i.e., the emphasis of specific syllables in the sentence), all subjects were tested twice 2 weeks apart. The results showed 1) there was significantly different sentence perception scores among the different time-altered conditions, yet only in the 60 % compression condition; 2) there was no significant difference of the sentence perception scores in the effect of stress; however, there was a positive effect of the selective word stress in the sentences consisting of 6 ~ 7 syllables at the 40 % compression condition; 3) there was no significant gender difference. The pattern of results suggests that the combination of time compression and selective word stress is more effective to understand speech, instead of only using time expansion condition. However, further studies should be needed for standardization.

• Journal of Chest Surgery
• /
• v.38 no.11 s.256
• /
• pp.746-760
• /
• 2005

Background: Following the implantation of heart valve prostheses, it is important to maintain therapeutic INR to reduce the risk of thromboembolism. The objectives of this study were to determine the causes of nontherapeutic INRs, and to identify the factors associated with nonadherences to warfarin therapy in Korean outpatients with prosthetic heart valves managed by a pharmacist-run anticoagulation service (ACS). Material and Method: A retrospective chart review was completed for all patients enrolled in the ACS at Seoul National University Hospital from March, 1997b to September, 2000. The data on 868 patients (5,304 visits) who were at least 6 months post-valve replacement were included. All possible causes of nontherapeutic INRs were documented for each patient visit. The association of covariates to noncompliance was investigated by univariate analysis. Result: The reasons for nontherapeutic INRs were identified as follows: inadequate dosage adjustment $(21\%)$, nonadherences to dosing regimen $(13\%)$, drug/herbal interactions $(12\%)$, changes in diet $(7\%)$, and indeterminate cause $(42\%)$. Younger age, shorter duration of ACS and longer duration of warfarin therapy were associated with nonadherence. Conclusion: In this study, nonadherence and interactions between diet and medications were found to be important factors influencing nontherapeutic INRs. Longer duration of enrollment in the ACS affected the adherence to warfarin therapy Positively whereas younger age and longer duration of warfarin therapy affected negatively.