• Economic and Environmental Geology
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• v.49 no.1
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• pp.63-75
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• 2016

The ratio of fractured reservoir is very high in oil & gas fields around the world. The demand of drilling technology for fractured reservoir is expected to increase continuously if oil and gas prices are economical. The purpose of the review study is to help operator or driller in selecting of proper drilling technology for preventing a lost circulation in the fractured formation. In order to achieve this goal, fractured reservoir(formation) they are classified into partial lost circulation formation and total lost circulation formation. In case of partial lost circulation formation, the drilling problem can be solved by using LCM(lost circulation material) mud additive and squeezing cement. For shallow depth, total lost circulation formation can be drilled safely and economically with casing drilling method. Also, for deeper depth, problems of total lost circulation in formation can be solved by applying mud cap, which is one of the drilling methods. This was confirmed through field application such as Italy's Medusa-1 field and Qatar's North field.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.30 no.4
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• pp.436-441
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• 1985

The study was conducted to provide basic information to breeders and agronomists working with sesame. The grain weight and germinability were investigated for eight plant types classified by branching habit, capsules per axil, and carpels and loculi of a capsule. Two typical cultivars were chosen for each plant type among 527 gene pools. Dry weight of one thousand grains was increased rapidly from 25th to 35th day after flowering, and reached peak on 40th day after flowering in upper part capsules and 45th day after flowering in lower and middle part capsules, so that this period was considered to be of physiological maturity in each capsule bearing part. Side capsules on main stem and branch capsules were lighter than central ones of main stem, and upper capsules of four carpels eight loculi type decreased more seriously. BTB type demonstrated relatively better growth compared to the growth of BTQ type in one thousand grain weight. The maximum grain filling duration for germination percentage increased rapidly up to 40th day after flowering. Above 70% germinability was obtained from 40th day after flowering. Harvesting time of physiological maturity was considered to be 45th day after flowering with peaks of 2.14g of one thousand grain weight, 26% of grain water content and 90% of germinability.

• The Journal of Dong Guk Oriental Medicine
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• v.9
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• pp.179-191
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• 2000

Anti-bone resorption properties of the Korean herbal medicine, CEDR, which is comprised 5 herbs of [Drynariae Rhizoma, Loranthi Ramus, Cibotii Rhizoma, Amydae carapax, Psoraleae semen], were investigated. Mouse calvarial osteoblast cells were isolated and cultured. Mouse osteoblasts, which were stimulated by PTH, $1,25(OH)_2D_3$, $TNF-\alpha$ and IL-1 as bone resorption agents, showed increased collagenolysis by producing the active gelatinase. IL-1 in stimulating bone resorption was examined using fetal mouse long bone organ culture. IL-1 stimulated bone resorption and produced marked resorption when present simultaneously. The results of in vitro cytotoxicities showed that CEDR extracts have no any cytotoxicities in concentrations of $1-60{\mu}g/ml$ and furthermore there is no any cytotoxicity even in concentration of $120{\mu}g/ml$ on mouse calvarial bone cells. CEDR extracts had protective activity against PTH (5 units/ml, or $IL-1{\alpha}$ (1 ng/ml) or $TNF-\alpha$ or $1,25(OH)_2D_3$ (20 ng/ml), $IL-1{\alpha}$ and $IL-1{\beta}-induced$ collagenolysis in the mouse calvarial cells. Pretreatment of the CEDR extracts for 1 h, which by itself had little effect on cell survival, did not enhance the collagenolysis, nor significantly reduced the collagenolysis by pretreatment. Furthermore, the medicinal extracts were shown to have the protective effects against collagenolysis induced by $IL-1{\alpha}$ and $IL-1{\beta}$. Pretreatment of the extracts for 1 h significantly reduced the collagenolysis. Interestingly, the CEDR extracts were shown to have the inhibiting effects against gelatinase enzyme and processing activity induced by the bone resorption agents of PTH, $1,25(OH)_2D_3$, $TNF-\alpha$, $IL-1{\beta}$ and $IL-1{\alpha}$ with strong protective effect in pretreatment with the extracts. CEDR extracts were shown to have the inhibiting effects against $IL-1{\alpha}-$ and $IL-1{\beta}-stimulated$ bone resorption and the effect of the pretreatment with a various concentrations of the medicinal extracts were significant. These results indicated that the CEDR extracts are highly stable and applicable to clinical uses in osteoporosis.