• Pediatric Infection and Vaccine
• /
• v.20 no.1
• /
• pp.28-35
• /
• 2013

Purpose : The aim of this study was to determine the frequency, epidemiology and the clinical manifestation of human metapneumovirus (hMPV) infection in Korean children. Methods : From February 2010 to January 2012, we collected nasopharyngeal aspiration from 1,554 children who were hospitalized for acute lower respiratory tract infections at the Department of Pediatrics, Severance Children's Hospital. hMPV was detected by performing reverse transcriptase-polymerase chain reaction (RT-PCR). The medical records of the patients with positive results were retrospectively reviewed. Results : We detected hMPV in 99 of the 1,554 hospitalized children. The mean age of the hMPV infected children was 25 months, and 87% of the illnesses occurred between April and June. The most common diagnoses were pneumonia (73%) and bronchiolitis (16%). The clinical manifestations included cough, fever, respiratory distress, hoarseness, tachypnea, and wheezing. Coinfection with other respiratory viruses was found in 43 children (43%). Conclusion : hMPV is one of the major virus causing acute respiratory tract infection in the age between 13 months and 48 months old with peaks during April to June. Reports of hMPV in Korea has been increasing but additional studies are required to define the epidemiology and the extent of disease caused by hMPV to determine future development of this illness in Korean children.

• 월간낙농육우
• /
• v.25 no.8 s.280
• /
• pp.148-152
• /
• 2005

근래에 발생되는 사육가축들의 질병발생 양상이 단독감염에 의한 것 보다 복합감염에 의한 발생이 많아지고 있고 치료기간도 길어지며 폐사하는경우도 종종 있어 피해도 점차 커지는 실정이다. 특히 송아지에서는 BVD와 다른 세균 또는 곰팡이 등과 복합감염되면 호흡기증상이나 소화기 증상이 매우 심하게 나타나는 경향이 있어 주의를 요하게 된다. 이번에 소개하는 예는 농가에서 사육하던 한우 17두가 BVD에 감염된 상태에서 곰팡이에 오염된 볏짚을 급여하여 심한 설사와

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.6
• /
• pp.113-120
• /
• 2016

The purpose of this study is to identify the knowledge of and adherence to the infection control guidelines for indwelling urinary catheters, central venous catheters and ventilators among intensive care nurses. The subjects were 175 intensive care nurses working in 2 upper general hospitals and 3 general hospitals. Data were collected from July 1 to July 31, 2013. The collected data were analyzed by descriptive statistics, t-test and ANOVA using SPSS 18.0 for Windows. The mean scores of the knowledge of the infection control guidelines on indwelling urinary catheters, central venous catheters and ventilators were 0.87, 0.82 and 0.82 points, respectively. The average scores for the adherence to the infection control guidelines for indwelling urinary catheters, central venous catheters and ventilators were 4.18, 4.04 and 4.07 points, respectively. Statistically significant correlations were found between the knowledge of and adherence to the infection control guidelines for indwelling urinary catheters (r=.72, p<.00), central venous catheters (r=.54, p<.001) and ventilators (r=.30, p<.001). The knowledge of and adherence to the infection control guidelines for indwelling urinary catheters differed significantly according to gender, educational status, total career, number of patients, type of hospital, and attendance of seminar. The knowledge of and adherence to the infection control guidelines for central venous catheters differed significantly according to educational status, total career, number of patients, type of hospital, and attendance of seminar. The knowledge level of the infection control guidelines for the ventilator differed significantly according to the total career. The results of this study indicate that education and training programs for improving the knowledge of adherence to the infection control guidelines should be developed.

• Journal of Veterinary Clinics
• /
• v.32 no.5
• /
• pp.445-448
• /
• 2015

A 5 month old Korean domestic short haired male kitten (weighing 1.7 kg) was presented with primary complaints of upper respiratory disease (URD) signs and skin ulceration and edema on face, feet and footpad with lameness. Diagnostic test revealed leukopenia, lymphopenia, pancreatitis and feline calicivirus (FCV) infection. Diagnosis of virulent systemic FCV (VS-FCV) was made on clinical signs, isolation of calicivirus via PCR and exclusion of other causes of acute upper respiratory disease. Therapeutic strategies were directed to lessen URD signs and to treat secondary bacterial infection and antiviral infection. One month after this therapy, skin lesions on face and feet and URD signs were much improved, although the lameness persisted mildly. To author's best knowledge, this is the first case reporting VS-FCV infection in a kitten in Korea.

• The Monthly Diabetes
• /
• s.221
• /
• pp.40-42
• /
• 2008

당뇨병환자들은 감염가능성이 일반인보다 높다. 또한 당뇨병환자에게서 감염이 있으면 혈당을 조절하기 어려워져 매우 위험하다. 피부감염증이나 족부감염증의 경우에는 그 발생빈도가 현저히 높아서 그 원인이나 증상, 예방법 등이 많이 알려져 있지만, 귀나 코, 그밖에 호흡기 등의 감염은 아직 그 정보가 부족하다. 국내 당뇨병환자가 점점 늘어나고 있는 상황에서 다양하게 나타나는 당뇨병 관련 증상들을 미연에 방지하고 올바르게 치료하기 위해 을지대학병원 감염내과 윤희정 교수와, 순천향대학병원 이비인후과 이병돈 교수의 도움말을 들어보았다.

• Pediatric Infection and Vaccine
• /
• v.26 no.3
• /
• pp.129-139
• /
• 2019

The human respiratory tract hosts both pathogenic and commensal bacteria. The development of well-conserved 16S rRNA sequencing and culture-independent techniques has enabled many achievements in the study of the human microbiome. Microbial composition of the respiratory tract in early childhood has been shown to correlate to respiratory health in later stages of life. This review highlights current understandings of respiratory microbiota development in healthy children, examples of microbial interactions, impacts on the host immune system, and the relationship between respiratory tract microbiome and respiratory health.

• KOREAN POULTRY JOURNAL
• /
• v.25 no.12 s.290
• /
• pp.123-127
• /
• 1993

겨울철이 되었다. 일반 계사는 밀폐되고 윈도레스계사 또한 휀 속도를 줄이게 되어 계사내는 먼지와 오염된 공기로 차게된다. 온도 또한 떨어진다. 얼른 떠오르게 되는 것이 호흡기질병이며 무엇인가 대책이 없을까 하는 것이다. 호흡기질병을 예방하기 위해서는 환기, 보온, 소독, 백신, 약제투여란 5박자에서 환기, 보온, 소독과 약제는 다 아는 사실이나 백신 응용에 관한 문제는 아직까지 가격이 비싸기 때문에 경제성 문제로 많이 사용되고 있지 않는 상황이다. 그러나 경제성에 대한 국내의 실제 성적은 아직까지 농장에서의 데이타가 미비하여 정확한 수치로 산출되지 못하고 있다. 이에 일본의 3군데 가족보건위생소에서 발표한 현장성적과 정리되지 않은 국내 사정을 참고하여 보면서 생산성 향상에 보탬이 될 수 있는 방법이 되었으면 한다. 닭이 마이코플라즈마 갈리셉티컴(MG)에 감염되면 호흡기 증상의 유무에 관계없이 산란저하와 중지란, 사롱란의 발생이 많이 일어나 경제적 피해를 입게되는데 이를 방지하기 위해 MG생독과 사독을 미국에서 먼저 개발하였으며 이를 여러나라에서 사용하고 있는 중이나, 일본에서는 1989년 사독백신을 개발하여 널리 사용하고 있으며 이들 백신은 닭에게 MG감염을 완전히 막아 주는 것은 아니나 호흡기 증상이나 기도 병변 형성을 억제함과 동시에 산란저하, 부하율저하 현상을 경감시켜주는 역할을 해내고 있다.

• Feed Journal
• /
• v.4 no.12 s.40
• /
• pp.136-141
• /
• 2006

소에서 발생하는 호흡기 질병은 가축이 가지고 있는 내적인 요인과 사육환경의 악화나 각종 스트레스 등의 외적인 요인과의 복합적인 균형의 파괴에서 시작된다고 볼 수 있다. 이와 같은 질병발생요인은 다른 축종이나 소화기 등 타 질병에서도 동인한 사항으로 생각될 수 있으나 호흡기질병의 경우 환경적인 요인이 더욱 중요한 발병이자로 작용하게 된다. 즉 밀집다두사육, 환절기의 낮과 밤의 큰 일교차, 환기불량이나 우사내의 유해가스, 장거리 수송 등의 스트레스가 일차적인 발병인자가 되며, 이타적으로 가축이 가지고 있거나 외부에서 유입된 여러 가지의 병원 미생물의 다량증식하고, 동물개체는 면역력이 떨어지면서 질병에 감염되어 단일 또는 복합적인 임상증상으로 나타나는 것이다. 호흡기질병의 원인균에는 다양한 종류의 세균 및 바이러스에 의해 이루어지며, 단일의 원인균에 의한 질병발생보다는 복합적으로 감염되어 병을 악화시키고 피해를 크게 하는 것이 일반적이다. 본고에서는 소에서 흔히 나타날 수 있는 주요한 세균성 호흡기 질병의 종류와 임상증상 및 일반적인 방제대책에 대하여 기술하고자 한다.

• Clinical and Experimental Pediatrics
• /
• v.52 no.6
• /
• pp.661-666
• /
• 2009

Purpose : To determine the prevalence and clinical features of codetected respiratory etiological agents for acute respiratory infection in hospitalized children. Methods : Nasopharyngeal aspirates were obtained from hospitalized children with acute respiratory infection at Dankook University Hospital from September 2003 through June 2005. Immunofluorescent staining and culture were used for the detection of respiratory viruses (influenza virus [IFV] types A, B; parainfluenza virus [PIV] types 1, 2, 3; respiratory syncytial virus [RSV]; adenovirus [AdV]). Polymerase chain reaction (PCR) assays were used for Mycoplasma pneumoniae (MP) and Chlamydia trachomatis (CT) detection, and PCR and culture were performed for enterovirus detection. Acid-fast staining and culture were performed for tuberculosis detection. The demographic and clinical characteristics were reviewed retrospectively from the patients medical records. Results : Evidence of two or more microbes was found in 28 children: RSV was detected in 14, PIV 3 in 10, AdV in 10, MP in 8, PIV 2 in 8, CT in 4, and PIV 1 in 3. Codetected agents were found as follows: RSV＋PIV 2, 6 patients; AdV＋MP, 4 patients; AdV＋PIV, 3 patients; RSV＋MP, 3 patients; PIV 1＋PIV 3, 3 patients. Distinct peaks of codetected agents were found in epidemics of MP and each respiratory virus. Conclusion : The codetected infectious agents were RSV, PIV, AdV, and MP, with distinct peaks found in epidemics of MP and each respiratory virus. Although advances in diagnostic methods have increased the prevalence of codetection, its clinical significance should be interpreted cautiously.

• Pediatric Infection and Vaccine
• /
• v.22 no.3
• /
• pp.143-146
• /
• 2015

Since 2012, outbreaks of the Middle East respiratory coronavirus (MERS-CoV) have been reported, including the Republic of Korea. To date, most of the people infected with the virus are adults. Herein we describe the clinical characteristics of cases of MERS-CoV infection among children. As of October 29, 2015, MERS-CoV has caused 34 pediatric infections, which accounts for 2.1% of all cases. The median age was 13 years (range 9 months to 17 years) and where gender has been reported (n=33), 57.6% cases were male. About half of the patients were asymptomatic and the majority of the symptomatic patients had respiratory symptoms. In general, the clinical outcome in children was favorable. Among the four patients who died of progressive pneumonia, three had documented comorbidities. MERS-CoV infection in children has a lower incidence and mortality compared to adults.