• Pediatric Infection and Vaccine
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• v.18 no.1
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• pp.23-30
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• 2011

Purpose : Acinetobacter baumannii is an aerobic, gram negative coccobacillus. Due to its pathogenicity and ability to accumulate diverse mechanisms of resistance, the importance of this organism is increasing. Many reports have targeted adults, and studies of pediatric patients are limited. This study aims to investigate the current status of A. baumannii infection in children. Methods : From January 2001 to December 2008, 505 patients hospitalized with A. baumannii infection were enrolled. Admission records for underlying disease, duration of hospitalization, previous antibiotic use, location of admission, presence of ventilator care, and resistance to antibiotics were retrospectively reviewed and analyzed. Results : Hemato-oncological disease and neurological disease were 30.6% and 24.3% of all cases; therefore, these were the most common underlying diseases of patients with A. baumannii infection. Prevalence of A. baumannii infection was 78.1% in patients with previous antibiotic use, which was higher than that of the group not using previous antibiotic. And prevalence of multi-drug resistant and pan-drug resistant A. baumannii infection was 76.4% and 38.3% in patients with ICU care, 76.8% and 38.9% with ventilator care, and these were higher than the others. Rate of resistance to all groups of antibiotics showed a gradual increase to over 50% in 2008. Multi-drug resistant A. baumannii was 63.5% and pan-drug resistant A. baumannii was 48.2% of all cases. Conclusion : Prevalence of A. baumannii infection and resistance to antibacterial agents of A. baumannii is increasing. Adequate use of antibiotics and infection control should be emphasized in pediatric patients.

• Monthly Duck's Village
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• s.202
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• pp.24-31
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• 2020

불포화지방산이 풍부한 오리고기는 예로부터 보양식으로 많은 사랑을 받았다. 오리고기가 기력을 회복하는 음식으로 널리 알려진 이유는 필수 아미노산과 레시틴이라는 성분이 풍부하기 때문이다. 아미노산은 근력 향상에 도움을 주고 신체 능력을 강화하며 피로 해소에도 탁월한 역할을 한다고 알려지며, 레시틴이 부족할 경우 피로를 느끼고 면역력이 저하되기 때문에 꾸준하게 섭취를 해주는 것이 중요하다. 오리에 풍부한 비타민A는 체내 병균 저항력을 높여준다. 또한 면역 세포의 기능을 촉진해 감염 질환이 걸리지 않게 몸을 보호하는 역할을 한다. 특히 비타민A가 부족하면 호흡기계 질환이 걸리기 쉬우므로 호흡기 건강에 신경을 쓴다면 평소 비타민A가 풍부한 음식을 먹는 게 좋다. 또한 오리고기에 풍부한 리놀레산은 성장기에 꼭 필요한 필수 지방산으로 인체 기능에 꼭 필요한 요소다. 다른 육류에 비해 열량이 낮고 단백질이 풍부해 다이어트를 할 때도 부담없이 즐길 수 있는 오리고기 신제품을 소개한다.

• Tuberculosis and Respiratory Diseases
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• v.44 no.3
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• pp.592-600
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• 1997

Background : The level of imposed work of breathing (WOB) is important for patient-ventilator synchrony and during weaning from mechanical ventilation. Triggering methods and the sensitivity of demand system are important determining factors of the imposed WOB. Flow triggering method is available on several modern ventilator and is believed to impose less work to a patient-triggered breath than pressure triggering method. We intended to compare the level of imposed WOB on two different methods of triggering and also at different levels of sensitivities on each triggering method (0.7 L/min vs 2.0 L/min on flow triggering ; $-1\;cmH_2O$ vs $-2cm\;H_2O$ on pressure triggering). Methods : The subjects were 12 patients ($64.8{\pm}4.2\;yrs$) on mechanical ventilation and were stable in respiratory pattern on CPAP $3\;cmH_2O$. Four different triggering sensitivities were applied at random order. For determination of imposed WOB, tracheal end pressure was measured through the monitoring lumen of Hi-Lo Jet tracheal tube (Mallincrodt, New York, USA) using pneumotachograph/pressure transducer (CP-100 pulmonary monitor, Bicore, Irvine, CA, USA). Other data of respiratory mechanics were also obtained by CP-100 pulmonary monitor. Results : The imposed WOB was decreased by 37.5% during 0.7 L/min on flow triggering compared to $-2\;cmH_2O$ on pressure triggering and also decreased by 14% during $-1\;cmH_2O$ compared to $-2\;cmH_2O$ on pressure triggering (p < 0.05 in each). The PTP(Pressure Time Product) was also decreased significantly during 0.7 L/min on flow triggering and $-1\;cmH_2O$ on pressure triggering compared to $-2\;cmH_2O$ on pressure triggering (p < 0.05 in each). The proportions of imposed WOB in total WOB were ranged from 37% to 85% and no significant changes among different methods and sensitivities. The physiologic WOB showed no significant changes among different triggering methods and sensitivities. Conclusion : To reduce the imposed WOB, flow triggering with sensitivity of 0.7 L/min would be better method than pressure triggering with sensitivity of $-2\;cm\;H_2O$.

• International Area Studies Review
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• v.13 no.3
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• pp.239-267
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• 2009

Investment in health through an array of public health policies will lead to improvement of health at all levels, and the improved health can reduce the socioeconomic costs incurred with diseases. And finally, with reduced healthcare costs associated with diseases and health problems, economy will be able to achieve economic growth and development. Using simultaneous equations model, this study aims to identify this possible channel from public health policies to economic growth. Specifically, the policy effect is investigated on a basis of main disease groups and aging groups. The public health policies are proved to reduce healthcare costs related with disease groups including respiratory, digestive, circulative, and infectious disease, and with all age groups except 20~39 group. And the reduced healthcare costs have shown to increase the real gross domestic products in those group above.

• Tuberculosis and Respiratory Diseases
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• v.65 no.5
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• pp.390-395
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• 2008

Background: Since the early 1980s, interferon-alpha ($IFN-{\alpha}$) has been used as adjuvant therapy in pediatric patients with recurrent respiratory papillomatosis (RRP). However, its efficacy in adults needs to be validated. Since 2002, Samsung Medical Center's guidelines have mandated regular injection of $IFN-{\alpha}$ in patients with RRP to prevent recurrence. To evaluate these guidelines, patient data were investigated. Methods: Five patients diagnosed as having RRP by bronchoscopy and histopathology were included. After initial bronchoscopic intervention, including laser cauterization, all patients received subcutaneous injection of 6 million units of $IFN-{\alpha}$ every 2 months. Further bronchoscopic intervention was carried out as needed. Patients were regularly evaluated using bronchoscopy or computed tomography. Results: The median age of the patients was 44 years (range 13~68), and the median duration of papillomatosis was 31 years (range 1~45). Three and two patients had juvenile-onset and adult-onset disease, respectively. Two patients had a history of tracheostomy at the time of diagnosis. The median duration of $IFN-{\alpha}$ therapy was 56 months (range 12~66). Two patients showed complete remission at 12 and 36 months after $IFN-{\alpha}$ injection, respectively. The other three patients showed partial remission, and the number of laser therapy sessions was significantly reduced.Conclusion: Intermittent $IFN-{\alpha}$ injection is effective in patients with long-standing RRP and can reduce the number of laser therapy sessions required in their treatment.

• Journal of agricultural medicine and community health
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• v.22 no.2
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• pp.253-263
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• 1997

농촌지역은 도시지역에 비하여 의료자원의 부족으로 보건의료자원의 이용 접근성이 낮다고 할 수 있다. 따라서 일부 농촌지역주민의 질병이환과 이환시 보건의료자원의 이용양상을 분석하는 것은 매우 의의가 있다고 하겠다. 본 연구방법은 포천군 주민의 보건의료자원의 이용과 치료원의 이용 양상을 분석할 목적으로 1995년 8월 4일~20일까지 1,200가구를 대상으로 가구 면접조사를 실시하였다. 분석대상 가구수는 1,019가구였으며 훈련받은 조사원에 의하여 조사되었으며 경기도 포천군 지역은 연세대학교 보건대학원 및 간호대학의 연구사업지역으로 본 분석 자료는 연세대학교 연구자료의 일부를 사용하였다. 연구 결과는 다음과 같다. 성별인구분포는 남자가 49.9%, 여자가 50.1%이고 연령별 분포는 60세 이상이 16.5%로써 전국의 노인인구 비율보다 높았다. 교육상태는 13년 이상 교육이수율이 남자가 여자보다 높았으나 전체 조사 대상 인구는 교육수준이 높았다. 가족 형태는 핵가족이 70.9%로써 농촌지역임에도 매우 높았다. 지난 15일간의 이환상태를 조사한 결과 급성이환율은 5.4%(54/1,000)이며 3개월 이상 만성이환율은 130/1,000으로 나타났다. 급성이환시 증상별 분포는 호흡기계질환이 36.4%, 소화기계가 20.9%, 여러 가지 복합 증상이 33.0%을 나타낸 반면 만성이환율은 관절염 및 류마티즘이 21.2%, 기타 골격계가 12.6%로서 높았다. 급성 이환시 의료이용양상은 포천군관내의 의료기관이용이 62.6%, 약국이용이 15.2%, 보건소 이용이 4.0%였으며 의료기관이 주요 이용자원이었다. 아무 조치를 취하지 않은 비율은 6.1%로서 높지 않았다. 즉 극성질환인 경우 전체이환자의 76.5%가 1회 방문으로 문제를 해결한 것으로 나타난 반면 나머지 23.5%가 2회 이상 의료자원을 이용한 것으로 나타났다. 3개월이상 만성이환자는 포천군관내 의료기관의 이용율이 56.3%, 관외의료관 이용이 19.3%인 반면 한방기관이용이 7.6%로서 급성이환시 한방이용비율인 4.0%보다 높았다. 1회 방문이 67.4%인 반면 2회 이상 보건의료자원을 이용한 비율이 33.6%로서 만성질환 이용시 보건의료자원의 이용 빈도가 높은 것으로 나타났다. 본 분석결과 포천군 주민의 주요 보건의료자원의 이용은 의료기관으로 나타났고 미치료율이 타농촌지역에 비하여 낮았으며 만성질환시 급성이환시보다 한방의료이용이 높았음을 나타났다.

• Clinical and Experimental Pediatrics
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• v.48 no.4
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• pp.401-405
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• 2005

Purpose : The use of mechanically-assisted ventilators at home reduces morbidity and improves the quality of life in children with chronic respiratory failure. But in Korea there is no clinical data of children with home mechanical ventilation. We investigated ventilator types, duration, the causes of failure or death, and the cost needed for care. Methods : We retrospectively analyzed the medical records of 21 children who were admitted and who applied for home mechanical ventilation at the Pediatric Intensive Care Unit in Asan Medical Center. Phone interviews took place after discharge. and interviewed by phone after discharge. Results : The median age was 31 months; the median duration with ventilator was 25 months. Underlying diseases were 16 neuromuscular diseases, one metabolic disease and four chronic respiratory diseases. The types of ventilator were pressure and volume type(16 and five patients, respectively). The frequency of ventilation failure was once per 19 months. Weaning could be performed in three cases. Frequencies of admission after receiving ventilators were 1.7 times per year; the most common cause was pneumonia. Nine patients(43%) died; four of them died because of endotracheal tube obstruction. The costs for medical care were about 1,110,000 won per month. Conclusion : There is an increment in the numbers of individuals who need mechanical ventilation support. The most common cause of death was endotracheal tube obstruction. The most important problem for the patients was medical cost. There needs to be more interest in patients with ventilator and social welfare systems to support their families need to be prepared.

• Tuberculosis and Respiratory Diseases
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• v.41 no.4
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• pp.372-378
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• 1994

Background: Pressure support ventilation(PSV) is a new form of mechanical ventilatory support that assists spontaneous inspiraory effort of an intubated patient with a clinician-selected amount of positive airway pressure. Low level pressure support during inspiration can overcome the resistive component of inspiratory work imposed by an endotracheal tube. However the clinical efficacy of PSV as a weaning method has not been established yet. Object: The aim of study was to evaluate the efficacy of PSV when it is added to intermittent mandatory ventilation(IMV) in facilitating weaning precess compaired to IMV mode alone. Method: When the subject patients became clinically stable with their arterial blood gas analysis in acceptable range, they underwent weaning process either by IMV alone or by IMV plus PSV. The level of pressure support was held constant throught the weaning period. For the patients who required mechanical ventilation for less than 72 hr, 2h weaning trial was performed with IMV rate starting from 6/min. For the patients who required mechanical ventilation more than 72 hr, 7 hr weaning trial was performed with IMV rate starting from 8/min. For the patients who failed three consecutive trials of weaning, retrial of weaning was attempted over 3 days with IMV rate starting from 8/min. Clinical characteristics, APACHE II score and nutritional status were compared. For all patients, heart rate, mean blood pressure and respiratory rate were mornitored for 48 hrs after weaning trial started. Results: The total number of weaning trial was 37 in 23 patients(18 by IMV, 19 by IMV+PSV). Total ventilation time, APACHE II score and nutritional status were not statistically different between the two groups. The weaning success rate were not statistically different(38.3% by IMV, 42.1% by IMV+PSV) and the changes of mean blood pressure, heart rate, respiratory rate during first 48 hours were not different between the two groups. Conclusion: Low level PSV when added to IMV for weaning trial does not seem to improve the success rate of weaning from mechanical ventilation. PSV at 10cm $H_2O$ did not induce significant physiologic changes during weaning process.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.12 no.6
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• pp.57-63
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• 2012

Effective use of stethoscope is very important for primary clinical diagnosis for the increasing cardiovascular and respiratory disease. This study developed the contact vibration sensor using piezopolymer film which minimizes the ambient noise, and signal processing algorithm was applied for providing better auscultation sounds compare to the existing electronic stethoscopes. Especially, low frequency heart sounds were acquired without distortion, and the quality of lung sounds were improved. Also, auscultating sounds could be transmitted using bluetooth, which made possible to be used for the u-healthcare environment. Results of this study, auscultation of heart and lung sounds, could be applied to the convergence industry of medical and information communication technology through remote diagnosis.

• Journal of the Korean Society of Food Science and Nutrition
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• v.20 no.4
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• pp.346-353
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• 1991

This survey was carried out to study the food habit and several health indicators of 438 persons (male ; 179, female ; 259) aged over 60 years old living in a middle city, The results obtained were as follows. The food habit of male was better significantly than that of female, the eating frequencies of fruits, eggs, meats and fishes, and legumes of male were higher than those of female. The mean weights and heights of both male and female were low in comparison to the Korean standard, but the mean BMIs of both male and female showed normal range and the mean obesity rates of male and female were 3.5％ and 8.2％, respectively, The mean hemoglobin content and hematocrit were 13.1g/100m1 and 39.8% in male, and 12.4g/100m1 and 37.8％ in female, respectively, The anemia rate judged by the WHO level of hemoglobin content was 42.0% in male and 34.7％ in female. The mean systolic and diastolic blood pressures of both male and female showed normal range; But the incidence of hypertension judged by the WHO level was 15. 6% in male and 16.7% in female. The subjects suffering from diseases were 78.2% in male and 86.7% in female. Common diseases were neuralgia, circulatory system diseases, respiratory system diseases, diabetes mellitus, and athritis. There were positive correlations between the score of food habit and body weight, height, hemoglobin content, and hematocrit. And there was a negative correlation between the food habit score and obesity rate. Systolic and diastolic blood pressures were correlated positively to skinfold thickness and the incidence of suffering from diseased.