• Title/Summary/Keyword: 호기중알코올농도

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Natural herbal extract complex induces the degradation of alcohol and acetaldehyde and reduces the breath alcohol concentration (천연소재복합물의 알코올 및 아세트알데히드 분해활성 및 호기중 알코올 농도 감소)

  • Hwang, Ji Hong;Kim, Mi-Yeon
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.3
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    • pp.381-392
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    • 2020
  • This study is purposed to check up the natural 12 kinds of herbal extracts suitable for hangover and based on the results of contents of phenolic compounds, ABTS radical scavenging activity, alcohol dehydrogenase (ADH), and acetaldehyde dehydrogenase (ALDH). Selected 8 kinds of herbal extracts are blended according to the efficacy and the pearson's correlation between each content and activity. C. sinensis var. sinensis, P. densiflora Gnarl and P. lobata Ohwi showed excellent ADH activity, P. lobata Ohwi had a strong correlation between the content and efficacy, and C. sinensis var. sinensis, P. densiflora Gnarl had a negative correlation. Through the ADH and ALDH activity test of F.1 to F.7, the F.7 showed the highest synergic effect and selected as an optimal formulation. F.7 intake-group, the breath alcohol concentration was significantly reduced to 58% after 30 minutes and 27% after 120 minutes, compared to right after alcohol consumption. After alcohol consumption, there was a significant improvement effect (p<0.05) in tired and thirst in the intake group compared to the non-intake group.