• 순환기질환의공학회:학술대회논문집
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• 2005.12a
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• pp.23-24
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• 2005

위와 같은 결과로부터 개인마다 다르게 형성되는 혈관의 형상이 혈류역학적 특성을 변화시켜 동맥경화의 발생에 영향을 미치고 있음을 알 수 있었다. 즉, 동일한 관상동맥일지라도 기하학적 형태변화에 따라 좌주간지의 길이가 짧을수록, 좌전하행지와 좌회선지의 분지부 각도가 넓을수록, 동맥경화의 발생이 용이한 형태가 되는데, 이로 미루어 혈관의 형상이 혈류의 유동조건을 변화시켜 혈관내피세포의 손상, 혈류의 정체시간 연장 등으로 나타나 동맥경화가 발생되는 인자가 된다.

• Applied Microscopy
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• v.33 no.4
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• pp.299-313
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• 2003

The aim of the present study was to assess the role of protein kinase C (PKC) in the development of cardiac injury following scald burn. Sprague-Dawley rats were induced a scald burn a 15% total body surface area. Phorbol 12-myristate 13-acetate (PMA, 2 mg/kg) and bisindolylmaleimide (BIS, 0.05 mg/kg) were immediately administered i.p. after burn injury. 5 h and 24 h later, heart was removed and examined biochemical assay, ultrastructural changes and stereological analysis. The activity of serum aspartate aminotransferase was significantly increased at 5h (p<0.01) and 5h+BIS (p<0.001) after burn compared with that of control. The activity of serum creatinine was significantly decreased in PMA-treated groups after burn compared with postburn 5 h. PMA caused a decrease in MPO activity and induced wavy fibers in cardiac myocytes at postburn 5 and 24h. BIS induced contraction band, separation of intercalated disk and abnormal mitochondria in cardiac myocytes at postburn 5 and 24h. In stereological analysis, treatment of rats with PMA increased volume density of myofibril and mitochondria compared with postburn 5 and 24h. Our data suggest that the activation of PKC in scald burned heart decreases inflammation and protects the myocardium.

• Journal of the korean academy of Pediatric Dentistry
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• v.29 no.3
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• pp.450-454
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• 2002

Laceration of soft palate and oropharynx is relatively common in children. Soft palate laceration has been reported patients of all ages, ranging from new born to geriatric patients. However, young children often place objects their mouth, they may fall on the object or receive a direct force on the object which then perforates the soft palate tissue. Most frequently affected site is the left supra-tonsillar area. Lesions are predominately in the soft palate with-out perforation. Linear and superficial wounds are frequent. A typical injury is the flat- U-, or V-shaped with apex directed anteriorly. In those cases without any through-and-through lacerations or any tissue loss, suture is not necessary. Furthermore, suture of the affected site may hinder wound healing. Healing of the wound should be complete by three weeks with minimal scarring. There have been reports of carotid artery injury due to soft palate laceration causing neurologic complications. For such reasons, traumatized child must be in close observation for 2-3days, and if symptoms of complication are noticed consultation with oromaxillofacial surgeons, E.N.T., or neurologist is required. These are two reports of boys 2 and 3 years of age who had soft palate laceration caused by a falling-down-in jury with an object in their mouth. They were treated non-surgically and neurologic evaluation was carried out for 1 week with complete healing.

• Investigative Magnetic Resonance Imaging
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• v.18 no.3
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• pp.232-243
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• 2014

Purpose : To evaluate the incidence of secondary contiguous or non-contiguous subchondral bone impactions (SBI) in subaxial cervical spinal injury and associated primary injury patterns. Materials and Methods: A retrospective review of computed tomography, magnetic resonance imaging, and medical records was carried out for 47 patients who had sustained a subaxial cervical spinal injury. Presence, number, level, and sites of secondary contiguous or non-contiguous SBI were recorded. To evaluate primary injury patterns, the level and number of primary injury sites of subaxial cervical spine injury, injury morphology, anterior/posterior discoligamentous complex (ADC/PDC) injury, posterior ligamentous complex (PLC) injury, spinal cord injury, and mechanism of injury (MOI) were analyzed. Differences in primary injury pattern of subaxial cervical spine injury and MOI between patients with and without SBI, and between contiguous or non-contiguous SBI were analyzed using the Mann-Whitney U test, Pearson's chi square test and Fisher's exact test. Results: Eighteen patients (18/47, 38.29%) had developed contiguous (n=9) or non-contiguous (n=9) SBI, most commonly involving T3 (15/47, 31.91%) and 3 levels (6/18, 33.33%). All SBIs had developed near the anterosuperior region of the body and the superior endplate and were the result of a high-impact MOI. SBIs were statistically significant in association with injury morphology and PLC injury (P=0.001, P=0.009, respectively) at the primary injury site. Non-contiguous SBI was more frequently accompanied by upper cervical spinal injuries in association with PDC injuries, as opposed to contiguous SBI, with statistical significance (P=0.009), while no other statistically significant differences were found. Conclusion: Secondary SBIs are common and probably associated with subaxial cervical spinal injuries with high energy compressive flexion forces.

• Journal of fish pathology
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• v.6 no.1
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• pp.65-70
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• 1993

The delicate histological structure of gill in teleosts can be easily affected by a variety of biological, chemical or physical detrimental agents because it is directly exposed to the surrounding water. The epithelium of secondary lamella is thin to allow efficient gaseous exchange and this also renders it particularly vulnerable to various pathogens. As well as the main respiratory role, the gill has other various important functions such as acid-base balance, osmoregulation or the excretion of nitrogenous waste products. Thus destruction of epithelial integrity such as epithelial necrosis or thickening can render a fish very vulnerable to respiratory, secretory and excretory difficulties. This article was tried to describe in detail the common processes of pathological responses correlated to the normal histological structures of the gill in teleosts.

• The Journal of the Korean dental association
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• v.54 no.2
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• pp.142-148
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• 2016

본 연구의 목적은 특이한 C형 치근과 근관을 가지고 있는 상악 제 1대구치의 근관치료 증례를 콘빔단층촬영을 사용하여 진단 및 치료하였음을 보고하는 것이다. 본 증례에서는 특이적인 해부학적 근관 형태가 콘빔단층촬영을 사용하여 확인되었으며 비외과적 근관치료가 시행되었다. 촬영한 영상에서 모든 치근이 C 형태로 융합되어 있으며 독립적인 4개의 근관을 포함하고 있음이 관찰되었다. C형 근관계의 복잡성을 고려할 때 콘빔단층촬영이 적절한 근관계의 확인과 의원성 손상을 예방하기 위해 유용한 보조적 방법인 것으로 보여진다.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2000.05a
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• pp.434-435
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• 2000

참돔 이리도바이러스 질병(red seabream iridovirus disease ; RSIVD)은 1990년 일본 시코쿠지역의 참돔 양식장에서 처음 발병된 후, 매년 발병지역이 확산되고 발병 어종이 다양해지고 있다. 참돔에서 분리된 RSIV는 icosahedral cytoplasmic deoxyribovirus로서 크기가 200∼240nm이며 형태학적 특징에 의해 iridoviridae로. 분류하고 있지만, 어류를 숙주로 하는 iridovirus과 중에서 lymphocystis virus속인 flounder virus(LCDV-1) 및 lymphocystis disease virus(LCDV-2)와 goldfish virus 1-lke virus속인 goldfish virus 1(GFV-1) 및 goldfish virus 2(GFV-2)와는 전혀 다른 바이러스로 알려져 있다. (중략)

• Journal of Ocean Engineering and Technology
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• v.3 no.2
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• pp.45-50
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• 1989

원유의 발견과 함께 북극의 개발이 활발해저왔고, 지역의 특수한 환경적인 요건으로 인해 시설물의 개발, 설치, 이동, 운용에 많은 어려움을 갖고 있다. 특히 빙산에 의한 극지 해안가의 해저면은 파이고, 손상되고, 변형된다. 북 알라스카의 해저면을 고르지 못하고, 불규칙하게 파이고, 손상된 형태를 보여주고, 특히 빙산의 활동이 활발한 지역과 시기에는 그 손상이 더욱 심하고, 자주 일어난다. 빙산에 의한 해저면의 홈은 빙산 해저 끝이 해저면에 접촉하여 해저 바닥을 파 나갈때 일어나는 현상이다. 빙산의 운동에너지는 해저면을 파 나가는 에너지로 변형되고, 그 힘이 평형하게 될 때까지 빙산의 운동은 계속된다. 빙산에 의한 해저면 손상은 극지 해안가의 해저시설물의 설계, 설치, 운용에 중대한 영향을 끼친다. 그러므로, 해저면 손상의 데이타 분석은 해안의 개발과 시설물의 설치에 큰 도움이 된다. 이 논문에서는 8년간에 걸친 약 십만개가 넘는 데이타를 토대로 알라스카 뷰오포트 해안가의 빙산에 의한 해저면 손상의 통계학적인 연구결과를 보여준다. 또한 각 변수의 최대치와 수심에 따른 변수의 최대 경계선을 추정하였고, 변수들의 상호관계를 연구하였다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.157-159
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• 2009

본 논문에서는 세라믹을 비파괴 검사를 통하여 얻어진 영상에서, 조직의 이상이나 결함의 정도를 자동으로 확인하는 방법을 제안한다. 비파괴 검사를 통하여 얻어진 영상에서 소벨 마스크를 적용하여 윤곽선을 추출하고, 추출된 윤곽선의 방향 정보를 $9{\times}9$ 마스크에 적용하여 영역을 분류한다. 그리고 분류된 각 영역을 히스토그램 스트레칭을 적용하여 영상을 보정하고, 4 방향 윤곽선 알고리즘을 적용하여 객체를 추출한다. 그리고 추출된 객체의 영역에 대해 형태학적 정보를 이용하여 잡음을 제거한 후, 손상된 영역을 추출한다. 본 논문에서 제안한 방법을 비파괴검사를 통하여 얻어진 영상을 대상으로 실험한 결과, 손상된 영역을 비교적 정확히 검출되는 것을 확인하였다.

• Current Research on Agriculture and Life Sciences
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• v.1
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• pp.201-214
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• 1983

A study was undertaken on rats in order to clarify the gastric mucosal, morphologic response to oral and subcutaneous administration of acetylsalicylic acid(aspirin). Aspirin was administered orally (oral group) and subcutaneously (subcutaneous group) at does rate of 60 mg per kg of body weight per day to 40 normal rats. On the 1st, 3rd, 7th, and 15th day of administration, in addition to clinical observation, 5 rats each from the both groups were sacrificed and examined macroscopically, histologically and electron-microscopically for the morphological changes of gastric mucosal cells with the following results. Although the clinical, macroscopic and histological changes were not significant, marked ultrastructural changes were observed. Parietal and chief cells were affected most severely by the administration of aspirin ; parietal cells showed increase in the number of SER and intracellular canaliculi, where-as in chief cells fragmentation, luminal dilatation, decrease in the number and structural abnormalities of RER were seen. Relatively mild changes were observed in mucous, mucous neck and basal-granulated cells. Although the degree of changes was milder than those of oral group, the similar changes were also observed in the subcutaneous group. From these results, it would be concluded that aspirin injury of gastric mucosa is effected not only by the direct injury to the mucosa but also indirectly by the blood concentration of aspirin.