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Effects of Selenium and Metallothionein on the Toxicity of Cadmium in Rats (카드뮴 투여후 셀레늄과 Metallothionein의 독성효과)

  • Ryu, Yong-Wun;Lee, Kee-Ho
    • Journal of Radiation Protection and Research
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    • v.17 no.1
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    • pp.11-19
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    • 1992
  • To find out an effective way of treating the toxicity of cadmium, concentrations of $K^+,\;Ca^{2+}$ and c-AMP, and activities of GOT and GPT in blood of rats were determined at definite time intervals after administration of cadmium to rats. Cadmium caused more decrease of $Ca^{2+}$ concentration than $K^+$ concentration but increases of GOT and GPT activities and of c-AMP concentrations. The decreased concentration of $Ca^{2+}$ was not recovered by selenium or metallothionein. However, the increased activities of GOT and GPT, and the c-AMP concentration were down regulated remarkably by selenium but not by metallothionein. These results suggested that selenium might have the compensate effects concerning toxic index against cadmium such as increases of GOT and GPT activities, and of c-AMP concentration.

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Effect of Arrowroot Flower (Puerariae flos) Extract on Lowering of Ethanol Concentration in Rat Blood (갈화(Puerariae flos)추출물이 Rat 혈중 Ethanol 농도에 미치는 영향)

  • Kim, Jeong-Han;Min, Sun-Sik;Kim, Sung-Hoon;Hong, Heu-Do;Kim, Jong-Soo;Kim, Soo-Un
    • Applied Biological Chemistry
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    • v.38 no.6
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    • pp.549-553
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    • 1995
  • Ethanol concentration in blood, brain and liver of rats was shown to be effectively lowered by arrowroot flower extract. The lowering effect for ethanol concentration in blood was maximum when measured after 1 hour from ethanol feeding. Hot water extract was more effective than 80% ethanol extract. The treatment of extract at 10 min. before ethanol feeding gave a better result than that at 10 min after or 1 hour before ethanol feeding. The ethanol concentration in brain and liver was lowered as found in the blood ethanol concentration. Acetaldehyde was not detected either in blood or the tissues. The optimal amount of the Puerariae flos was 55.7 mg/kg body weight. The newly developed analytical method using dichloromethane as extracting solvent was proven to be very effective in terms of speed and simplicity.

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Convergence Study on Effects of Passive Stretching on Blood Fatigue and VAS after Delayed Onset Muscle Soreness (지연성근육통 유발 후 수동적 스트레칭이 혈중피로물질 및 VAS에 미치는 융합연구)

  • Kim, Jong-Hyuck;Kim, Do-Jin
    • Journal of Convergence for Information Technology
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    • v.8 no.6
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    • pp.93-99
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    • 2018
  • The purpose of this study was to prove the effect of passive stretching after delayed muscular pain induction in university students and to propose a rehabilitation exercise program for effective pain relief and prevention in case of injury. Subjects were divided into passive stretching group and control group. Passive stretching group was performed passive stretching after delayed muscular pain induction and control group did not perform any treatment after delayed muscular pain induction. The delayed muscular pain induction method was induced by bench step motion. The height of the step box was 50cm. The data were analyzed by two-way RGRM ANOVA for comparison of passive stretching group and control group. In conclusion, passive stretching after delayed myalgia has a positive effect on blood fatigue (CRP, LDH) and subjective pain scale(VAS).

Changes in cognitive, concentration and performance in Bowling player Associated with Magnesium Water Supplementation (마그네슘 음료 섭취에 따른 볼링선수들의 인지기능과 집중력 및 경기력의 변화)

  • Kim, Kwan Kyu;Chung, Young Hee;Nam, Jung Hoon;Cho, In Ho;Park, Noh Hwan;Lim, Byung Yun
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.1
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    • pp.333-339
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    • 2019
  • The purpose of this study is to clarify the effect of magnesium water on the cognitive function, concentration and performance of bowling players. The total number of subjects in this study was 42, and changes in blood magnesium concentration, cognitive ability, concentration and performance were identified during the four-week experiment period. Data distribution was analyzed using SPSS18.0 with Normality test and Repeated measure two way ANOVA. Studies show that the concentration of magnesium in the blood of bowling players has changed with the intake of magnesium drinks, and that the concentration of magnesium in the blood has a proportional relationship with the cognitive function, concentration and performance.

Variation of the Oral Intake and Exposure Characteristics of Pb among Young Ages in Korea: Data Analysis of 2011-2017 KNHANES (우리나라 청소년의 납 경구 섭취량 및 노출 특성의 변화 : 2011-2017 국민건강영양조사 자료 분석)

  • Moon, Chan-Seok
    • The Journal of the Korea Contents Association
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    • v.22 no.4
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    • pp.706-713
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    • 2022
  • The study is to observe the time trend variation in the blood lead concentration of Korean teenage groups and to examine the changes in the daily lead intake from intake amount(g) by food groups as an influencing factor. A total of 1,540 subjects are participants in the Korea National Health and Nutrition Examination Survey (KNHANES) in 2011, 2012, 2014, 2016, and 2017. The blood lead concentrations were 1.25㎍/100ml in 2011 survey, 1.16㎍/100ml in 2012, 1.17㎍/100ml in 2013, 1.05㎍/100ml in 2016, and 0.84㎍/100ml in 2017. The time trend decrease in food intake amount appeared mainly in the plant food groups such as grains, potatoes and starch, pulses, mushrooms, vegetables, and fruits. And the milk and dairy products of the animal food group also showed a decreased trend. The decrease in the intake amount of these food groups can be an influencing factor in the decrease in lead concentration in the blood.

Effects of Long-distance Horseback Riding on Blood Lipid, Adipokine, Inflammatory Marker in Obese Middle Aged Women

  • Lee, Jin-Wook;Park, Jong-Hwa
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.8
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    • pp.185-194
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    • 2022
  • The purpose of this study was to verify the effects of long-distance horseback riding on blood lipid, adipokines and inflammatory markers in obese middle-aged women. The subjects of this study were 9 obese meddle aged women and the data analysed using the paired t-test. The result of this study were as follows: First, TC(p<.01), LDL-C(p<.01), and HDL-C(p<.001) were significantly increased after long-distance horseback riding(LDHR). Second, adiponectin was significantly increased(p<.01) and also PAI-1 was significantly decreased(p<.01) after LDHR. Third, IL-6 was significantly increased(p<.01) after LDHR. These results suggest that long-distance horseback riding has positive effect on changes blood lipid, adipokines, and inflammatory markers in obese middle-aged women. Therefore we consider that effects of long-distance horseback riding has partial examine on prevention and therapy of obesity in middle-aged obese women who undergo physical and emotional big changed.

Verification of the Effectiveness of a combined Exercise Program for Improving the Health of the Elderly (노인건강증진을 위한 복합운동프로그램의 효과 검증)

  • Soon-Gi Baek
    • Journal of Industrial Convergence
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    • v.21 no.12
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    • pp.75-81
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    • 2023
  • This study was conducted to verify the effectiveness of a combined exercise program to improve the health of the elderly. For this purpose, 10 people in the exercise group and 10 in the control group were selected among seniors aged 65 years or older. The subject of this study was a 12-week combined exercise program in which aerobic and anaerobic exercise were performed three times a week for 60 minutes. Before participating in exercise, blood lipid and inflammatory index tests were conducted, and blood lipid and inflammatory index tests were conducted upon completion of the combined exercise program. The test results were verified with basic statistics and treatment effects between groups using the SPSS statistical program. Based on this, the following conclusions were obtained. First, the combined exercise program for elderly health promotion showed significant differences in TC, LDL, and TG in blood lipids between the exercise group and the control group, and there was an interaction effect on the treatment program. Second, the combined exercise program for improving the health of the elderly showed significant differences in inflammatory indicators IL-6 and TNF-a between the exercise group and the control group, and there was an interaction effect with the treatment program.

The Association between Blood Selenium Level and the Gastric Diseases (혈중(血中) 셀레늄 농도(濃度)와 위장질환(胃臟疾患)의 관련성(關聯性))

  • Lee, Jong-Young;Kim, Doo-Hie;Park, Seoung-Kook
    • Journal of Preventive Medicine and Public Health
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    • v.21 no.1 s.23
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    • pp.172-182
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    • 1988
  • To reveal the association between blood selenium level and the gastric diseases, 180 persons received the gastrofiberscopic examination at the outpatients department of the two university hospitals from July to September 1987, after the exclusion of the persons having the esophageal varix, were randomly selected. Their general characteristics such as age, sex and educational level and so on, were inverstigated. Five mi venous blood was collected from each subjects and stored at $0^{\circ}C$ in heparinized vaccum tube. The blood selenium level was measured by the flameless atomic absorption spectrophotometry. In the procedure of data analysis, five subjects having benign tumor and anomaly of the stomach, were also excluded. The mean blood selenium levels of the $155.5{\mu}g/{\ell}$ among gastritis cases, the $154.8{\mu}g/{\ell}$ gastric ulcer and the $133.0{\mu}g/{\ell}$ gastric malignancy were significantly lower(p<0.05) than that of the $173.3{\mu}g/{\ell}$ among normal controls. In men the mean blood selenium levels .among gastritis, gastric ulcer and gastric malignancy cases were significantly lower(p<0.05) than that among normal controls. In females, the mean blood selenium levels among gastritis and gastric maligancy cases were significantly lower(p<0.05) than that among normal controls($169.7{\mu}g/{\ell}$), but that among gastric ulcer cases($177.7{\mu}g/{\ell}$) was not significantly higher. In the logistic analysis, coefficient of the blood selenium level was -0.0436(p<0.05 : odds ratio 0.957) for gastritis, -0.0197(p=0.17 : 0.981) for gastric ulcer, -0.4876(p<0.05 : 0.614) for gastric malignancy and -0.0411(p<0.05 ; 0.960) for gastric diseases including the gastritis, the gastric ulcer and the gastric malignancy. These data support the hypothesis that the gastric diseases are to be associated with the low selenium level but, for the gastric ulcer, the further research is recommended.

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Changes of the Preoperative and Postoperative Nutritional Statuses in Patients with Gastric Cancer and Assessment of the Nutritional Factors That Are Correlated with Short-Term Postoperative Complications (위암 환자에서 수술 전후의 영양지표의 변화와 수술 후 단기간 합병증과의 연관성)

  • Oh, Cheong-Ah;Kim, Dae-Hoon;Oh, Seung-Jong;Choi, Min-Gew;Noh, Jae-Hyung;Sohn, Tae-Sung;Kim, Sung;Bae, Jae-Moon
    • Journal of Gastric Cancer
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    • v.10 no.1
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    • pp.5-12
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    • 2010
  • Purpose: The aim of this study was to evaluate the preoperative and postoperative nutritional statuses of patients with gastric cancer and to investigate the nutritional factors that are correlated with perioperative complications. Materials and Methods: From January 2008 to Jun 2008, 669 patients who underwent curative gastrectomy were enrolled in a retrospective study. To evaluate the changes of their nutritional status preoperatively and postoperatively, we measured the total lymphocyte count, the serum albumin, the body weight change and the BMI. The nutritional factors correlated with short-term postoperative complications were analyzed. Results: The total lymphocyte count and serum albumin decreased from the first preoperative day to the $5^{th}$ day after operation, but they tended to increase and approach the normal range 6 months after operation. The only factor correlated with the short-term postoperative complications (defined as the ones that occurred for 30 days) was the serum albumin checked on the $5^{th}$ day after operation. Conclusion: Low serum albumin on the $5^{th}$ day after operation was correlated with postoperative short-term complications. Serum albumin can be the preoperative statistical parameter that can predict the occurrence of postoperative complications.

Differences of Blood Oxygen Saturation between 20s and 60s due to Amount of Highly Concentrated Oxygen Administration (고농도 산소 공급량에 따른 20대와 60대의 혈중 산소 포화도의 차이)

  • Choi, Mi-Hyun;Kim, Ji-Hye;Lee, Su-Jeong;Yang, Jae-Woong;Yi, Jeong-Han;Jun, Jae-Hoon;Kim, Hyun-Jun;Lee, Tae-Soo;Chung, Soon-Cheol
    • Science of Emotion and Sensibility
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    • v.13 no.1
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    • pp.41-46
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    • 2010
  • The purpose of this study was to examine differences between 20s and 60s in blood oxygen saturation due to 93% oxygen administration of the three levels(1L/min, 3L/min, 5L/min). Ten 20s male($25.0{\pm}1.8$ years), ten 20s female($23.7{\pm}1.9$ years), ten 60s male($68.0{\pm}2.6$ years), and ten 60s female($65.5{\pm}3.1$ years) were selected as the subjects for this study. The oxygen supply equipment(OXUS Co.) provided oxygen by supply rate(i.e., 1L/min, 3L/min, and 5L/min) at a constant rate of 93% oxygen. The experiment consisted of three phases, i.e., Prehyperoxia(5min), Hyperoxia(10min), and Post-hyperoxia(5min). Blood oxygen saturation were measured throughoutthe three phases. By increasing the amount of highly concentrated oxygen administration, blood oxygen saturation was increased. Blood oxygen saturation of 20s was higher than 60s. Blood oxygen saturation was greater during Hyperoxia than during Pre- and Post-hyperoxia. However, rising rate of blood oxygen saturation of 60s by oxygen administration was higher than 20s.

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