• Title/Summary/Keyword: 혈연관계

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Prediction of Genomic Relationship Matrices using Single Nucleotide Polymorphisms in Hanwoo (한우의 유전체 표지인자 활용 개체 혈연관계 추정)

  • Lee, Deuk-Hwan;Cho, Chung-Il;Kim, Nae-Soo
    • Journal of Animal Science and Technology
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    • v.52 no.5
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    • pp.357-366
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    • 2010
  • The emergence of next-generation sequencing technologies has lead to application of new computational and statistical methodologies that allow incorporating genetic information from entire genomes of many individuals composing the population. For example, using single-nucleotide polymorphisms (SNP) obtained from whole genome amplification platforms such as the Ilummina BovineSNP50 chip, many researchers are actively engaged in the genetic evaluation of cattle livestock using whole genome relationship analyses. In this study, we estimated the genomic relationship matrix (GRM) and compared it with one computed using a pedigree relationship matrix (PRM) using a population of Hanwoo. This project is a preliminary study that will eventually include future work on genomic selection and prediction. Data used in this study were obtained from 187 blood samples consisting of the progeny of 20 young bulls collected after parentage testing from the Hanwoo improvement center, National Agriculture Cooperative Federation as well as 103 blood samples from the progeny of 12 proven bulls collected from farms around the Kyong-buk area in South Korea. The data set was divided into two cases for analysis. In the first case missing genotypes were included. In the second case missing genotypes were excluded. The effect of missing genotypes on the accuracy of genomic relationship estimation was investigated. Estimation of relationships using genomic information was also carried out chromosome by chromosome for whole genomic SNP markers based on the regression method using allele frequencies across loci. The average correlation coefficient and standard deviation between relationships using pedigree information and chromosomal genomic information using data which was verified using a parentage test andeliminated missing genotypes was $0.81{\pm}0.04$ and their correlation coefficient when using whole genomic information was 0.98, which was higher. Variation in relationships between non-inbred half sibs was $0.22{\pm}0.17$ on chromosomal and $0.22{\pm}0.04$ on whole genomic SNP markers. The variations were larger and unusual values were observed when non-parentage test data were included. So, relationship matrix by genomic information can be useful for genetic evaluation of animal breeding.

A Study on key attributes to congenital disease factors regarding the patients of the four most-common serious chronic illnesses and their relatives in the light of Myeongrihak -centering on the elderly in Seoul nursing homes- (4대 중증질환자와 혈연 관계자에 대한 명리학적 선천성질환 특성요인 분석 -서울시 요양원 입소노인을 중심으로-)

  • Kim, Il-Sin;Cho, Sung-Je
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.11
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    • pp.5610-5615
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    • 2013
  • The objective of this study is to identify key attributes to congenital disease factors regarding the patients of the four most-common serious chronic illnesses and their relatives in the light of Myeongrihak. For the purpose of this study, a survey was conducted from March 15 to July 31, 2013, of 147 elderly people with the four most-common serious chronic illnesses admitted to nursing homes located in Seoul. Data were analyzed by frequency analysis and Kai-square tests by use of SPSS/WIN 18.0. The analysis found that the patients and their relatives had very similar disease factors, and cerebrovascular diseases presented the strongest correlations. The subjects also showed meaningful differences according to the health factors of their relatives. As this study found that meaningful correlations regarding congenital diseases between patients of the four most-common serious chronic illnesses and their relatives in the light of Myeongrihak, this will serve as basic data to predicts health conditions of families and relatives.

Development and Applications of A Paternity and Kinship Analysis System Based on DNA Data (유전자 분석 자료에 의한 친자 및 혈연관계 분석시스템 개발 및 활용)

  • Koo, Kyo-Chan;Kim, Sun-Uk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.10
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    • pp.6715-6721
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    • 2015
  • Recently, DNA data of missing person, killed person, and missing child continue to increase but most of statistical calculation for paternity confirmation is being done through manual methods or Excel. Therefore, we need development of a software which is able to facilitate both systematic management and effective analysis of Short Tandem Repeat (STR) derived from DNA data. Without extensive testing, through a twenty-month study was developed a web-based system which performs paternity analysis and kinship analysis easily based on the various options. The former uses an existing algorithm for paternity index and the latter does Identity by descent (IBD) formula. Due to our system validated over real datasets in terms of likelihood ratio and probability of paternity, it ensures increased reliability as well as effective management and analysis of DNA data in mass disaster. In addition, it includes advanced features such as an integrated environment, user-centered interface, process automation and so on.

Mothering Attitude in 『Light in August』 (『팔월의 빛』에 나타난 모성적 태도)

  • Choi, Sunwha
    • Journal of Convergence for Information Technology
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    • v.9 no.2
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    • pp.94-99
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    • 2019
  • With a special attention to the effects of his different mothering environments on the formation of the children's identity and sociality, and on their growing up into a mature personality under various types of mothering attitudes, this thesis is to tell the significance of the mothering attitude in Faulkner's novel, Light in August. Lena Grove's "tolerant mothering attitude" in Light in August accepts the existence of things as they are and takes the substance over the form. The message for the writer to deliver must be Lena's "tolerance and holding mothering attitude environment." And it is the most required for a child to establish his or her identity and sociality as a human being and to grow up into a mature person.

A Study on the Mutual Support between Married Women and Their Mother-in-law and their Mother (기혼여성의 시어머니 및 친정어머니와의 상호지지에 관한연구)

  • 유영주
    • Journal of Families and Better Life
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    • v.12 no.1
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    • pp.209-219
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    • 1994
  • 부모-자녀관계의 주된 역할자인 기혼여성과 어머니(시어머니, 친정어미니) 간에 교류되고 있는 정서적 경제적 서비스 지지의 제공과 수혜를 조사하여 봄으로써 부모-자녀관 계의 변화를 추론해보고자한다. 본 연구결과 기혼여성은 시어머니와의 관계에서는 정서적 경제적 서비스 지지의 수혜보다 제공을 많이 하였으며 친정어머니와의 관계에서는 지지의 제공보다 수혜를 많이 받는 것으로 나타났다. 그리고 시어머니와 친정어머니간의 지지를 비교해 본결과 정서적 지지는 제공과 수혜 모두 시어머니보다 혈연관계인 친정어머니와의 사이에서 많이 교류되고 있으며 경제적 서비스 지지는 제공은 시어머니에게 많은 하고 수혜는 친정어머니로부터 많이 받는 것으로 나타났다. 이렇게 친정으로부터 지원받고 시가에는 봉사하는 '친정지원,시가봉사'의 이중적인 가족구조는 기혼여성에서 전통적으로 부과되어온 시부모부양의 의무를 계속 가질 뿐 아니라 친정에도 봉사하며 양가관계를 유지해야 이중부담 을 갖게 되는 문제점으로 나타날 수 있다.

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Indigenous psychological analysis of delinquency among Korean adolescents: Comparison of adolescents under probation and high school students (한국 일탈 청소년의 토착심리 탐구: 보호관찰 청소년과 일반 청소년의 부모자녀관계에 대한 비교를 중심으로)

  • Young-Shin Park ;Uichol Kim ;Soo Yeon Tak
    • Korean Journal of Culture and Social Issue
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    • v.10 no.1
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    • pp.107-145
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    • 2004
  • This study examines factors that influence delinquency among adolescents under probation using indigenous psychological analysis, focusing specifically on parent-child relationship. A total 268 adolescents under probation and their parents and 251 high school students and their parents participated in the two studies. In the first study, qualitative results indicate that both groups of adolescents were most likely to trust their parents than any other person and reason for their trust is reported to be based on blood relationship. Similarly, majority of parents of both groups reported trusting their children because of the blood relationship. Parents hope that their children will be sincere a person and will be able to maintain harmonious social relationship. Parents of adolescents under probation were more likely to report disobedience as being most problematic, whereas parents of high school students were more likely report providing social and financial support for their children's education as being the most difficult. In the second study, structured questionnaires were administered to the four groups and the following set of results were obtained. First, in terms of family background, the socio-economic status of adolescents under probation was lower, they are less likely to live with both parents or natural parents, and more likely to have ran away from home than high school students. Second, adolescents under probation are less likely to trust their parents and more likely to view their parents as being hostile. Third, parents of adolescents under probation were less likely to trust their children, more likely to view their relationship as being conflictual and hostile, and feel that they had to sacrifice for their children when compared with parents of high school students. Implications of these results for parent-child relationship and delinquency are discussed.

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Regionalization of the Lineage Group in Korea(II): Landscape Phase(16C~17C) (종족집단의 지역화과정에 관한 연구(II): 경관생산단계 - 16~17세기 계보의식의 탄생과 사회관계망의 공간적 확장 -)

  • 전종한
    • Journal of the Korean Geographical Society
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    • v.38 no.4
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    • pp.575-590
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    • 2003
  • It was the landscape phase that social relations were extended by production of landscapes during the 16C~17C. Core lineage groups in study area had extended socio-spatial nexus through making of the landscape of ‘authority-ostentation’(권력-과시형 경관) and of ‘kindness-civilization’(시혜ㆍ교화형 경관). Therefore they could gain a result that their power and authority took root in community perfectly. In the case of the Kims of Kwangsan(광산김씨), the first landscape of ‘kindness-civilization’ was Jungheodang(the learning room Jungheo), and next it was built Yangsungdang(the learning room Yangsung), and Imlijung(the pavilion Imli). Through this landscape production, the consciousness of scholastic genealogy was born, and this genealogy consciousness could be deepened and extended in regional scale. One more important feature in this phase is the point that the Kims of Kwangsan in Yeonsan area and the Songs of Unjin(은진송씨) in Hoiduk area could unite socially by the landscape production of ‘kindness-civilization type’ becoming intermediation. And these social union, that is to say, it do connote enlargement of the territoriality. It tells that community of ‘regional’ scale was formed by of core lineage groups of ‘local’ uniting each other.

Comparison of Breeding Value by Establishment of Genomic Relationship Matrix in Pure Landrace Population (유전체 관계행렬 구성에 따른 Landrace 순종돈의 육종가 비교)

  • Lee, Joon-Ho;Cho, Kwang-Hyun;Cho, Chung-Il;Park, Kyung-Do;Lee, Deuk Hwan
    • Journal of Animal Science and Technology
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    • v.55 no.3
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    • pp.165-171
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    • 2013
  • Genomic relationship matrix (GRM) was constructed using whole genome SNP markers of swine and genomic breeding value was estimated by substitution of the numerator relationship matrix (NRM) based on pedigree information to GRM. Genotypes of 40,706 SNP markers from 448 pure Landrace pigs were used in this study and five kinds of GRM construction methods, G05, GMF, GOF, $GOF^*$ and GN, were compared with each other and with NRM. Coefficients of GOF considering each of observed allele frequencies showed the lowest deviation with coefficients of NRM and as coefficients of GMF considering the average minor allele frequency showed huge deviation from coefficients of NRM, movement of mean was expected by methods of allele frequency consideration. All GRM construction methods, except for $GOF^*$, showed normally distributed Mendelian sampling. As the result of breeding value (BV) estimation for days to 90 kg (D90KG) and average back-fat thickness (ABF) using NRM and GRM, correlation between BV of NRM and GRM was the highest by GOF and as genetic variance was overestimated by $GOF^*$, it was confirmed that scale of GRM is closely related with estimation of genetic variance. With the same amount of phenotype information, accuracy of BV based on genomic information was higher than BV based on pedigree information and these symptoms were more obvious for ABF then D90KG. Genetic evaluation of animal using relationship matrix by genomic information could be useful when there is lack of phenotype or relationship and prediction of BV for young animals without phenotype.

A Research on Relative Cultivation through Appellations in Chinese (중국 호칭어를 통한 친족문화 연구 - '사(姒)', '제(娣)', '질(姪)'의 비교를 통한 잉첩혼(媵妾婚) 문화(文化))

  • Yu, Hyuna
    • Cross-Cultural Studies
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    • v.41
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    • pp.229-243
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    • 2015
  • When ancient Chinese people called their relatives, both the marriage system and their blood ties are reflected in the kinship terms. For examples, the ancient China's unique marriage system, "yingqiehun," is reflected in kinship terms, like "shi," "di," and "zhi," which reflect the fact that women relatives married the same person, and thus resulting from the polygamy. Furthermore, there are good reasons to assume that there are master-and-servant relationships, as evidenced through the kinship terms "yingqiehun" from the beginning of polygamy. In this paper we will study the feature of their unique marital culture, "yingqiehun" by analyzing each meaning of "shi," "di," and "zhi" and other examples, and will also examine the cause of its prevalence at that time.

The Situation of Genetic Exchange in Duroc Breed and Impacts on Genetic Evaluation (국내 듀록의 종돈장간의 교류현황과 유전능력평가에 미치는 효과)

  • Seo, Jae-Ho;Shin, Ji-Seob;Noh, Jae-Kwang;Song, Chi-Eun;Do, Chang-Hee
    • Journal of Animal Science and Technology
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    • v.53 no.5
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    • pp.397-408
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    • 2011
  • The study was carried to identify the impact on nation-wide genetic evaluation and to obtain basic materials for the development of strategies in Swine Improvement Network Project (SINP). Data consisted of pedigree records of 235,511 and performance records of 70,747 for Duroc from 1987 to 2010 were collected by Korea Animal Improvement Association. Performance traits included three point back fat thickness (Shoulder, Belly, Waist), loin area, days to 90 kg and average daily gain. Exchange of genetic resources cross the breeding farms was not high, and furthermore the sizable farms which can accommodate genetic evaluation within the farm were scarce. Three data sets (individual farm evaluation: I, two sub-group evaluation: S, and whole eight farm evaluation: P) were used for genetic analysis. Genetic variances were larger in subordinate farms than in joiners farms for connectedness, and consequently the heritabilities were generally higher in subordinate farms than in joiner farms with I. The standard errors of heritability were small in the order of I, S and P. Estimated average inbreeding coefficients were 1.12%, 0.95% and 1.53% for joiner and subordinate group with S and population with P, respectively. The estimated correlations of breeding values with I and P were lowest. The correlations of breeding values with I and P for traits ranged 0.22 to 0.45 for moved parent animals and 0.24 to 0.72 for all animals. The results in the study suggest that nation-wide evaluation uses more pedigree information and improves accuracy. Furthermore SINP for connectedness could help to improve the accuracy of evaluation.