• Title/Summary/Keyword: 혈액학

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Hematology and Serum Chemistry Values of Growing Miniature Pigs (성장 미니돼지의 혈액 및 혈청화학 성분의 연구)

  • Jung, Joo-Hyun;Chang, Jin-Hwa;Kim, Hak-Sang;Yoon, Jung-Hee;Choi, Min-Cheol
    • Journal of Life Science
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    • v.18 no.8
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    • pp.1169-1172
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    • 2008
  • The purpose of this study was to establish blood reference values for miniature pigs from various growth ages before pre-puberty. 12 miniature pigs from two swine farms were sampled by jugular venipuncture. Routine hematological and biochemical determinations were performed using whole blood and serum. For the variables examined in each age group the means and the standard deviations were calculated. In hematological values, there are significant changes (p<0.05) in RBC, hematocrit and platelet values in each group. In RBC and hematocrit values, 4-week group shows the lowest level, whereas in platelet values, 4-week group shows the highest level. In biochemical values, there are significant chnges (p<0.05) in glucose and GGT in each group, and in other biochemical values there are no significant changes during growing periods. The values presented here may be useful for knowing the normal values for miniature pigs and also screening the normal pigs in the early days of their life and during the developemental stages.

랫트에 있어서 절수, 절식 및 절수 절식이 혈액학 및 혈액생화학적 PARAMETERS에 미치는 영향에 관한 연구

  • 한상섭;송창우;이치호
    • Toxicological Research
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    • v.7 no.1
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    • pp.51-59
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    • 1991
  • The purpose of the present study was to investigate the effects of non-watering, fasting and non-watering fasting for 16-17 hrs on haematological and biochemical parameters in SD rats. 1. Liver weight was decreased in the order of in the fasting group, non-watering fasting group and non-watering group in both sexes. 2. In fasting group and non-watering fasting group, haematologic parameters of male (HGB and MCH) and femal (MCHC) were trends to decrease compared with normal feeding & watering group. 3. In the differential leucocyte counts, there were no significant differences compared with noraml feeding % watering group.

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Effect of Airborne Lead Concentration Characterized by Size on Blood Lead and Their Relationships (납 흡수에 영향을 미치는 요인 분석: 납 크기 특성과 혈액중 납과의 관계)

  • Park, Dong-Uk;Ha, Kwon-Chul
    • Journal of Environmental Health Sciences
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    • v.31 no.4 s.85
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    • pp.316-321
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    • 2005
  • 4개 업종(축전지제조업, 광명단 제조업, 2차 제련업, 라디에타 제조업)에서 근무하는 총 100명의 근로자를 대상으로 8단계다단충돌기(eight stages personal cascade imparter)에 의한 입자 크기 별 납농도를 측정하였다 크기 별 납 농도는 총납(PbA), 흡입성납(IPM-PbA), 흉곽성납(TPM-PbA), 호흡성납(RPM-PbA), $1{\mu}m$ 미만의 납$(Pb_{1\mu})$ 그리고 $1{\mu}m$ 이상의 소화성납$(Pb_{ing})$이었다. 동일한 근로자(100명)를 대상으로 혈액에서 납농도를 측정하였다. 혈액 중 납은 원자흡광광도계(atomic absorption spectrometry)의 Zeeman effect graphite furnace를 이용하여 분석하였다. 총 납의 노출농도는 노출기준$(50\;ug/m^3)$을 크게 초과하였다. 평균 호흡성 납 노출농도$(115.7\;ug/m^3)$ 총 납의 노출기준을 훨씬 초과하였다. $1{\mu}m$미만의 납$(Pb_{1\mu})$ 노출농도의 범위는 0.7에서 $(492.2\;ug/m^3)$이나 되었다. 근로자의 $46\%$가 혈액 중 납 농도 40 ug/dL을 초과하였다. 60 ug/dL을 초과한 경우도 $13\%$나 되었다. 입자 크기가 큰 납인 총납, 흡입성 납 그리고 호흡성 납 농도는 혈액 중 납 농도와 유의한 상관을 보였다(p<0.0001). 그러나 가장 높은 상관은 $1{\mu}m$미만의 납$(Pb_{1\mu})$ 혈액 중 납과의 관계였다. T-test에서 $50ug/m^3$이상의 호흡성 납을 나타낸 근로자 그룹과 $50ug/m^3$ 이하의 근로자 그룹간에의 혈액 중 납 농도는 유의한 차이가 있는 것으로 나타났다(p=0.000). 이러한 연구결과는 입자크기 구분이 없는 현재의 총납에 의한 노출기준과 측정방법은 미세 납 먼지에 노출되는 근로자의 납흡수를 보호하는데 한계점이 있다는 것을 의미한다. 향후 납 입자크기는 물론 근로자의 개인적인 위생과 작업내용 등을 변수로 납 흡수에 영향을 미치는 종합적인 요인을 찾아내는 연구를 진행할 필요가 있다.

Determination of Toxic Elements in Blood by Inductively Coupled Plasma Mass Spectrometry

  • Park, Chang-Jun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.3 no.1
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    • pp.99-99
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    • 1993
  • 혈액 및 생체시료 중 필수원소 혹은 독극성 원소의 극미량상분 정밀측정과 동위원소비율측정에 널리 사용되는 유도결합플라즈마 질량분석기(ICP-MS)의 기본원리를 소개하고 ICP-SM를 이용한 혈액중 낮은 ppb수준의 Cd, Hg 그리고 Pb의 정밀분석법을 소개한다. 혈액은 많은 양의 유기물을 포함하고 있으므로 digestion bomb에 질산과 과산화수소를 넣어 microwave oven에서 고온고압 상태로 분해시켜 많은 용액을 얻어 이 용액을 플라즈마에 주입시켜 분석한다. 그리고 수온은 tin(II) chloride 용액을 환원제로하여 생성시킨 수은원소증기를 membrane liquid-gas separator를 이용하여 뽑아내어 플라즈마에 주입시켜 낮은 ppt 수준의 검출한계를 얻는다. 또한 높은 정밀도와 정확도와 극미량 원소 측정에 사용되는 동위원소 회석법율 소개하고 실제 혈액분석에의 응용방법을 제시한다.

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A STUDY OF SHEAR BOND STRENGTH OF ORTHODONTIC BRACKET UNDER BLOOD-CONTAMINATED CONDITIONS (혈액 오염 환경 하에서 접착된 교정용 브라켓의 전단 강도에 관한 연구)

  • Shin, Ji-Sun;Kim, Jong-Soo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.32 no.2
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    • pp.191-199
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    • 2005
  • This study was experienced in order to obtain the shear bond strength of orthodontic bracket adhesives under the blood contamination that can be occurred during the procedure of bracket bonding under window opening surgery. As a result of this study, shear bond strength of all glass ionomer groups were lower than resin cement groups. However, the strength of uncontaminated and post-contaminated group of glass ionomer was strong enough to perform an orthodontic forced eruption. This study revealed that during a window opening surgery, glass ionomer without etching procedure is available in order to bond a bracket if surface of teeth is not pre-contaminated by blood before the adhesive application. Both simple procedure and less adhesives remnant after bonding failure could make light-cured glass ionomer cement the ultimate choice for racket bonding.

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The Experience of Life Reconstruction in Hemodialysis Patients with Chronic Renal Failure (만성신부전 혈액투석 환자의 삶의 재구성 경험에 관한 현상학적 연구)

  • Kim, Yun-Jeong;Kwon, Su-hye
    • Journal of Digital Convergence
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    • v.15 no.9
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    • pp.321-333
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    • 2017
  • This study was a qualitative study using Colaizzi's phenomenological study method to understand the experience of reconstructing life through hemodialysis in chronic renal failure patients and to clarify the meaning of their vivid experience. The participants were eight chronic renal failure patients receiving hemodialysis. Data were collected through individual in - depth interviews with participants. The five categories that were found in the study were 'The beginning of unexpected difficulties', 'Burden of survival brought on by hemodialysis', 'The driving force of recovery', 'Choices and concentration of today in order', ' Every day life which must be woven sincerely'. The results of this study will help clinicians better understand the physical and mental suffering experienced by patients with chronic renal failure receiving hemodialysis and how they are constantly trying to adapt to a changed lifestyle. Also it might provide basic data for the development of efficient nursing intervention for the health management of hemodialysis patients.

The Study on the Elderly Homodialysis Patients' Transition of Health Condition and Health-related Quality of Life (혈액투석노인의 건강상태 변화인식과 건강관련 삶의 질에 관한 연구)

  • Shim, Ok Su
    • 한국노년학
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    • v.30 no.1
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    • pp.179-194
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    • 2010
  • The purpose of this study examines the elderly hemodialysis patients' Health-related quality in life(HRQL) and investigates the relationship between HRQL and transition of health condition. The subject were 443 elderly hemodialysis patients(over 65 years old) in Seoul and Gyeonggi province. The Health-related quality of life scale was used in this research, in which were analysed a wide range of statistical descriptive analysis, Pearson's correlation, reliability analysis, multiple regression and the Scheffe test. The results were as follows. The HRQL were statiscally significant difference by Gender, Educational level, Live with spouse, Best supporter, and Number of Disease. Also the factor related to transition of health condition was Number of Disease. The transition of health condition accounted for 13.9% of variance in HRQL and Number of Disease accounted for an additional 7.4% of HRQL. The factors, which influenced finally on the HRQL in the elderly hemodialysis patients, were transition of health condition and number of disease. In conclusion adequate hemodialysis treatment and social services should be provided in accordance with the factors affecting HRQL in order to improve the HRQL for elderly hemodialysis patients.

Analysis of High School Students' Conceptual Change in Model-Based Instruction for Blood Circulation (혈액 순환 모형 기반 수업에서 고등학생들의 개념 변화 분석)

  • Kim, Mi-Young;Kim, Heui-Baik
    • Journal of The Korean Association For Science Education
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    • v.27 no.5
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    • pp.379-393
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    • 2007
  • The purpose of this article is to analyze the conceptual change of nine 11th graders after implementing the model-based instruction of blood circulation by multidimensional framework, and to find some implications about teaching strategies for improving conceptual understanding. The model-based instruction consisted of 4 periods: (1) introduction for inducing students' interests using an episode in the science history of blood circulation, (2) vivisectional experiment on rats, (3) visual-linguistic model instruction using the videotape of heartbeat, and (4) modeling activity on the path of blood flow. Based on the data from pre-test, post-test and interviews, we classified students' models on the path of blood flow, and investigated their ontological features and the conceptual status of blood circulation. Most students could describe the path of blood flow and the changes of substances in blood precisely after the instructions. However, the modeling activity were not sufficient to improve students' understanding of the mechanisms of the blood distribution throughout various organs and the material exchanges between blood and tissues. From the interview of 9 students, we acquired informative results about conceptual status elements that were helpful to, preventing from, or not used for students' understanding. It was also found that conceptual status of students depended on the ontological categories into which students' conceptions of blood circulation fell. The results of this study can help design the effective teaching strategy for the understanding of concept of the equilibrium category.