• Title/Summary/Keyword: 혈액생화학적 지표

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Study on Biochemical Pollutant Markers for Diagnosis of Marine Pollution III. Changes in Cholinesterase Activity of Flounder(Paralichthys olivaceus)in the Yellow Sea (해양오염의 진단을 위한 생화학적 오염지표에 관한 연구 III. 황해산 넙치(Paralichthys olivaceus)의 콜린에스테라아제 활성의 변화)

  • Choi, Jin-Ho;Kim, Dong-Woo;Moon, Young-Sil;Park, Chung-Kil;Yang, Dong-Beom
    • Journal of Life Science
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    • v.7 no.1
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    • pp.17-23
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    • 1997
  • This study was designed as a part of efforts to investigate the biochemical pollutant markers for diagnosis of maine pollutions by changes in cholinesterase activity of the flounder (Paralichthys olivaceus)in Yellow Sea of Korea. Acetylcholinesterase (AChE) activities in brain and muscle of cultured flounders in Yellow Sea were remarkably lower (40-50% and 40-55%, respectively)than those of wild flounder in Pohang (control) of East Sea, but AChE activities in brain and muscle of wild flounders in Yellow Sea were significantly lower(15-40% and 25-35%, respectively)than those of wild flounder in Pohang of East Sea. Butyrylcholinesterase(BChE) activities in barin and muscle of cultured flounders in Yellow Sea were remarkably lower(70-75% and 65-75%, respectively) than those of wild flounder in Pohang of East Sea, but BChE activities in barin and muscle of wild flounders in Yellow Sea were significantly lower (15-40%and 25-35%, respectively)than those of wild flounder in Pohang of East Sea. Lactate dehydrogenase (LDH) activities in serum of cultured flounders in Yellow Sea were significantly 10-50% higher than those of wild flounder in Pohang of East Sea, but LDH activities in serum of wild flounders in Yellow Sea were significantly 20-25% higher than those of wild flounder in Pohang of East Sea. It suggests that AChE and BChE activities in brain and muscle of cultured and wild flounders of Yellow Sea may be used as the most effective mean in a biochemical markers for diagnosis of pollutant effects by organophosphorus pesticides.

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Effects of Ginseng By-Products Supplementation on Performance, Blood Biochemical Profiles, Organ Development, and Stress Parameter in Broiler under Heat Stress Condition (인삼 부산물의 첨가 급여가 고온 스트레스 하 육계의 생산성, 혈액조성, 장기발달 및 스트레스 지표에 미치는 영향)

  • Jun-Ho, Lee;Ji-Won, Yoon;Bong-Ki, Kim;Hee-Bok, Park;Kyu-Sang, Lim;Ji-Hyuk, Kim
    • Korean Journal of Poultry Science
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    • v.49 no.4
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    • pp.255-264
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    • 2022
  • This study was performed to investigate the effects of dietary supplementation with ginseng by-products on growth, organ development, blood biochemical profiles, immune response, and stress parameter of broilers reared in high ambient temperatures. One hundred one-day-old male chicks (Ross 308) were used. At week two, the birds were randomly allocated into five dietary groups; control (CON), 0.5% ginseng berry (GB1), 1.0% ginseng berry (GB2), 0.5% ginseng leaves and stems (GLS1), and 1.0% ginseng leaves and stems (GLS2). The temperature was maintained at 32±1℃from 9 AM to 5 PM. Growth, serum immunoglobulins and corticosterone levels were monitored and analyzed. No significant differences among groups were observed in growth. However, during the finisher period (21~35d) and overall period (7~35 d), body weight gain in all supplemented groups tended higher than CON group. Blood biochemical profiles did not significantly differ among treatment groups except in bilirubin level. Serum immunoglobulins and corticosterone level showed no significant differences among groups. IgM and IgG levels were numerically higher in GLS1 than in other groups, but the difference was not significant. Corticosterone level also tended lower in all supplemented groups than in CON group, and larger decreases were observed in groups with higher ginseng by-product concentration. In conclusion, dietary supplementation of ginseng by-products shows potential to reduce heat stress in growing broilers with no negative effect on productivity.

Study on Biochemical Pollutant Markers for Diagnosis of Marine Pollution VII. Changes in Lipid Components of Flounder (Paralichthys olivaceus) in the South Sea (해양오염의 진단을 위한 생화학적 오염지표에 관한 연구 VII. 남해산 넙치 (Paralichthys olivaceus)의 지질성분의 변화)

  • CHOI Jin-Ho;KIM Dong-Woo;KIM Jung-Hwa;PARK Chung-Kil;YANG Dong Beom
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.6
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    • pp.882-888
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    • 1998
  • This study was designed as a part of efforts to investigate the biochemical pollutant markers for diagnosis of marine pollutions by changes in lipid components of the flounder (Paralichthys olivaceus) in the South Sea of Korea, Hemoglobin levels in serum of cultured flounders in the South Sea were lower ($4\~17\%$) than those of wild flounder in Pohang as a control group. Triglyceride (TG), Total and low density lipoprotein (LDL)-cholesterol contents in serum of cultured flounders in the South Sea were $12\~25\%,\;9\~19\%$ and $17\~25\%$ respectively which are higher than those of wild flounder in Pohang. Atherogenic index (AI) and T-Chol/PL ratios in serum of cultured flounders in the South Sea were significantly higher($26\~43\%$ and $17\~26\%$ respectively) than those of wild flounder in Pohang. These results suggest that near-coastal water as well as neritic water of the South Sea might be affected by pollutant input as well as the Yellow Sea of Korea.

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Study on Biochemical Pollutant Markers for Diagnosis of Marine Pollution II. Changes in Oxygen Radicals and Their Scavenger Enzymes of the Flounder(Paralichthys olivaceus) in the Yellow Sea (해양오염의 진단을 위한 생화학적 오염지표에 관한 연구 II. 황해산 넙치(Paralichthys olivaceus)의 산소라디칼 및 제거효소의 변화)

  • Moon, Young-Sil;Kim, Dong-Woo;Choi, Jin-Ho;Park, Chung-Kil;Yang, Dong-Beom
    • Journal of Life Science
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    • v.7 no.1
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    • pp.10-16
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    • 1997
  • This study was designed as a part of efforts to investigate the biochemical pollutant markers for diagnosis of marine pollutions by changes in oxygen radicals and their scavenger enzymes of the flounder (Paralichthys olivaceus)in Yellow Sea of Kores. Protein contents in brian and muscle of cultured flounder in Yellow Sea were remarkably lower(30-45% and 25-45%, respectively) than those of wild flounders in Pohang(control) of East Sea. Lipid peroxide(LPO) levels in serum of cultured and wild flounders in Yellow Sea were significanltly higher (30-80% and 125-145%, respectively)than those of wild flounder in Pohang. Hydroxide radical formations and superoxide dismutase(SOD) activities in serum of cultured flounders in Yellow Sea were significantly 15-30% and 15-35% lower than those of wild flounders in Pohang, but glutathione peroxidase (GSHPx) activities in brain of cultured flounders in Yellow Sea were significantly 15-25% higher than those of wild flounders in Pohang. It is believed that significantly decreases of protein contents in brain anad muscle, remakable increases of malondialdehyde(LPO) in serum and glutathione peroxidase (GSHPx)in brain of cultured flounders of Yellow Sea may be used as a biochemical pollutant markers for diagnosis of marine pollutions.

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Relationship among Body Composition, Biochemical Measurements and Serum Leptin Level in Obese Children (비만아의 체성분 및 생화학적 측정치와 혈중 Leptin 농도와의 관계)

  • 최봉순;손수진;이희자;박명희;이은주
    • Journal of Nutrition and Health
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    • v.35 no.4
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    • pp.454-463
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    • 2002
  • The purpose of this study was to investigate the relationship among the anthropometric measurements, body composition indices, biochemical indices and serum leptin level of obese school children. The study was conducted on 97 elementary school children from 4-5th grade residing in Daegu and Kyungbuk area. Obesity was defined as fat percentage that exceed 25% of body fat mass. The prevalence of obesity of subject was 58.3% for male and 54.1% for female. The mean value of height, weight, body composition indices and biochemical indices of obese group were significantly higher than those of control group. The leptin level was significantly different in obese group but showed no difference by gender. The differences of leptin level were according to adiposity and BMI in obese subjects. Multiple regression analysis data showed that the BMI and body fat mass may influence on the leptin level of subject. Also, these data revealed the leptin resistance in obese children and relationship between leptin level and various factors including anthropometric measurements, body composition and biochemical indices. Additional research should be necessary to assess the mechanism of leptin resistance in obese children.

The Effect of Mulberry Leaf Extract on Blood biochemical parameters in White Rats Exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (상엽 물추출물이 다이옥신 유도 독성에 대한 흰쥐의 혈액 생화학지표에 미치는 영향)

  • Lee, Yoon-Bok;Bae, Soo-Jeong;Lee, Da-Kyung;Park, Swung-Jae;Park, Ji-Won;Kim, Byung-Weon;Whang, Seok-Yeon
    • Journal of Digital Convergence
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    • v.11 no.1
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    • pp.299-308
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    • 2013
  • We investigated the effect of mulberry leaf extract (MLE) on blood biochemical parameters of white rats induced TCDD toxicity. Data were analyzed by One-way ANOVA and Post-Hoc Test. The numbers of leukocyte and platelet decreased by TCDD were increased dramatically after treated MLE (p<0.01). The concentration of calcium and magnesium decreased by TT were increased by MLE and shown a statistical significance (p<0.01) but the concentration of phosphorus increased by TT was decreased by MLE. In the test of parameters related to renal function, only the concentration of uric acid in the MLE group was decreased than it in TT group and shown a statistical significance (p<0.01). Also the concentration of blood glucose and the activity of amylase and lipase increased by TT were decreased after treated MLE and shown a statistical significance (p<0.01), and MLE had an control effect for elevating blood glucose. In the test of parameters related to liver function, the acticity of AST, ALT and ALP increased by TT was decreased after treated MLE and shown a statistical significance (p<0.01), and MLE had an improving effect for liver function. In the case of total cholesterol (T,cho), triglyceride( TG), LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) related to lipid metabolism, the amount of T,cho, TG, LDL-C increased by TT were decreased after treated MLE and shown a statistical significance (p<0.01), and MLE had an ability of anti-hyperlipidemia. From these results, we concluded that MLE could mollified TCDD toxicity in white rats exposed to TCDD.

Effect of Immunoglobulin Y on Growth Performance and Blood Immunological Parameters in Holstein Calves (난황항체(IgY) 급여가 Holstein 송아지의 성장능력 및 면역관련 혈액 지표에 미치는 영향)

  • Jung, Hee-Sung;Jung, Keun-Ki;Jang, In-Surk
    • Journal of Animal Science and Technology
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    • v.51 no.4
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    • pp.321-328
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    • 2009
  • A total of fourteen, 1-wk-old male Holstein calves were allotted into two groups consisted of control (CON) and IGY which was orally administrated with immunoglobulin yolk (IgY) for 1wk. Calves in both groups were provided with milk replacer according to feeding program and had ad libitum access to timothy hay for the entire experimental period (7wks). At 0, 7 and 49 day of experiment, blood samples were collected from the jugular vein of calves to investigate blood biochemical profiles and the differential count (%) of white blood cell (WBC). We also monitored growth performance and colony forming unit (CFU) of fecal microbial population in calves. The adminstration of IgY in calves did not affect body weight and weight gain during 49 days feeding trial compared with control group. The CFU of E. coli and Lactobacilli in the feces of calves were not significantly affected by IgY treatment, whereas the score of the calf scours during day 43 to 49 in IgY group showed a significant (P<0.05) solid type. There were no differences in plasma biochemical components including total protein, albumin, immunoglobulin and the other indicators. As for WBC differential count (%), there was no statistical difference in the percentages of neutrophil, lymphocyte, monocyte, eosinophil and basophil at 0, 7 and 49 days after the oral supplementation of IgY. In conclusion, the oral supplementation of IgY as an immunostimulant did not affect growth performance, fecal microbial population, blood biochemical profile and WBC differential count in Holstein calves.

The Food Classification in Sasang Constitution and Effects of Tae-eum Constitutional Diet on the Blood Biochemical Parameters and Health Status (사상의학의 체질에 따른 식품분류와 태음식 섭취가 각각 체질의 혈액 생화학적 지표 및 건강상태에 미치는 영향)

  • 김은진
    • Journal of Nutrition and Health
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    • v.32 no.7
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    • pp.827-837
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    • 1999
  • Presently Sasang constitutional medicine draws public attention and a diet based on this theory in gaining popularity. However, scientific data are not available to probe the effects of constitutional diet and the correlations between constitution and food consumptions. Thiry-four healthy subjects[26 females and 8 males] with Tae-eum(females: 5, males: 7), So-yang(females: 9)and So-eum(females: 12, males: 1), were studied. Subjects were not told the kind of constitutional diets they were consuming. Tae-eum constitutional diet was given to all subjects more than 2 meals a day for 8 weeks. The Sasang constitutional classification, food frequency questionnaire and food habits were assessed. The anthropometric assessment, dietary assessment, health status assessment and blood analysis were carried out before and after taking the Tae-eum constitution diet. In case of females, the body weights and BMI were different among the constitutional groups in the following order : Tae-eum constitutional diet. In case of females, the body weights the body weights and BMI were different among the constitutional groups in the following order: Tae-eum>So-yang>So-eum. In case of males, the body weights and BMI of Tae-eum were significantly higher than those of So-eum. In general, habitual food consumption of all of these four groups were very close to those for each of Sasang constitutional types described by Sasang medicine. After 8-weeks of Tae-eum diet, the health status and blood biochemical parameters were not significantly changed.

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Effects of Dietary Supplementation of Powdered Mulberry Leaves on Egg Production, Egg Quality and Blood Characteristics in Laying Hens (산란계 사료에 뽕잎 분말 첨가 급여가 산란율, 계란 품질 및 혈액 성상에 미치는 영향)

  • Park, Chang-Ill;Kim, Young-Jik
    • Korean Journal of Poultry Science
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    • v.39 no.3
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    • pp.215-222
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    • 2012
  • This study was conducted to investigate the effects of supplementation diets of powdered mulberry leaves on egg production, egg quality and blood characteristics in laying hens. Laying hens were fed diets for 30 days containing 0% powdered mulberry leaves (Control), 1% powdered mulberry leaves (T1), 2% powdered mulberry leaves (T2), and 5% powdered mulberry leaves (T3). The egg production, yolk weight and albumen weight were no significant difference among treatment groups. The albumen weight was significantly decreased by the supplementation of powdered mulberry leaves in all treatment groups (P<0.05). The albumen high, yolk color score, egg sell thickness and egg shell breaking strength were no significant difference. The total cholesterol and triglyceride concentration of control was higher than T3, and the high density lipoprotein (HDL)-cholesterol concentration and glucose of control were lower than treatment groups (P<0.05). The white blood cell (WBC) was significantly increased by the supplementation of powdered mulberry leaves compared to the control (P<0.05). In conclusion, these data indicate that 5% powdered mulberry leaves supplementation was most effective in decreasing total cholesterol and triglyceride and increasing HDL-cholesterol, glucose and WBC.

Effects of Nutrition Education and Exercise Program on Obesity Index and Behavioral Modification in Moderate Obese Women (영양교육과 운동을 병행한 프로그램이 중등도비만여성의 비만도와 행동변화에 미치는 효과)

  • Chang, Myung-Hee;Jung, Su-Jin
    • Korean Journal of Community Nutrition
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    • v.23 no.4
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    • pp.318-332
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    • 2018
  • Objectives: The purpose of this study was to investigate the behavioral modification of obese adults who underwent nutritional and physical activity education. Twenty obese females, aged 20-60 years old, with BMIs (Body Mass Index) >30 or body fat (%) >40 were subjected to this study. Methods: The physical activity education program consisted of doing exercise in a gymnasium together or home exercise. Dietary attitudes and dietary intakes were assessed using weight control, physical activity, and eating habits. The nutrition-exercise educational period was 12 weeks. Results: After the study period, there was significant improvement in physical activity and eating habits score. Furthermore, there was a significant increase in the dietary intakes of fiber, iron, potassium, vitamin A, vitamin $B_6$, and niacin. Blood pressure, blood glucose, and total cholesterol levels showed a tendency to decrease, but there was no significant difference. BMI, fat mass, abdominal circumference, and visceral fat levels were significantly reduced while muscle mass significantly increased. Conclusions: This study suggests that behavioral modification by nutrition and physical activity education with feedback has positive effects on dietary intake and anthropometric biomarkers in obese adults. Therefore, lifestyle interventions of this kind could be recommended as a method for obesity management.