• Analytical Science and Technology
• /
• v.17 no.3
• /
• pp.211-216
• /
• 2004

Commercial one-step rapid fecal occult blood (FOB) kit which was used as a screening test to detect traces of blood in stool samples was evaluated for the feasibility of the forensic identification of human blood. The sensitivity was determined and compared with the conventional Leucomalichite green (LMG) method. In addition, the specificity of the kit and the effects of various chemicals and environmental factors were examined. FOB kit was specific for human hemoglobin and more sensitive than LMG test (approximately 100 times). FOB kit showed positive band using at least 1,000,000-fold diluted human blood. The antigen was very stable regardless of storage temperature and boiling. The positive reaction was not affected by LMG and Luminol, the traditional tests for identification of bloodstain. As a results, FOB test kit could be effectively applied to identification of human blood at crime scene and crime laboratories.

• The Korean Journal of Applied Statistics
• /
• v.10 no.1
• /
• pp.47-60
• /
• 1997

Based on group testing, we present efficient blood testing procedures for the case of unknown prevalence rate.

• RED RIBBON
• /
• s.53
• /
• pp.16-17
• /
• 2003

얼마전 수혈로 인한 에이즈감염보도 이후 헌혈 혈액에 대한 의심이 커지고 있다. 현재 국내에서는 헌혈 혈액에 대해 어떠한 검사를 실시하고 있으며 왜 에이즈에 감염된 혈액이 수혈자에게 공급하게 되었는지 살펴보자.

• Journal of the Korean Society of Radiology
• /
• v.10 no.7
• /
• pp.495-502
• /
• 2016

In this study, we analyzed the effects of radiation exposure, as compared to the hematological parameters change of medical radiation workers and the public. The mean value of all hematological parameters were in the normal range. Eosin mean value of the radiation workers($2.52{\pm}1.79%$) showed that a significantly lower than the control group($2.92{\pm}1.39%$). In the comparison of the results depending on the occupation period, it showed high value that the mean of the radiation workers group WBC, platelet, Lymph, Mono, Baso. Over 20 years of radiation workers WBC, Mono showed low values and less than 10 years of radiation workers mean value of Baso showed low values, there was no statistical significance. In the comparison of the results depending on the 4 years cumulative radiation dose, Over 5.0 mSv of Radiation works RBC($4.61{\pm}0.53$ vs $4.91{\pm}0.38$), Hct($41.51{\pm}4.07$ vs $43.97{\pm}3.40$), Eosin($1.74{\pm}1.14$ vs $2.92{\pm}1.39$) showed low value, it was statistical significance. 0.5~1.0 mSv radiation exposure workers Hb ($13.93{\pm}1.75$) showed a significantly lower value than that of the control group ($14.90{\pm}1.29$).

• Journal of Preventive Medicine and Public Health
• /
• v.30 no.3 s.58
• /
• pp.623-629
• /
• 1997

This is cross-sectional study to evaluate a potential relationship between air conduction hearing threshold and blood viscosity in normal adult males(n=1677). We measured hearing threshold in frequency level at 500, 1000, 2000, 4000Hz by pure-tone audiometry and RBC profiles containing red cell number, hemoglobin, hematocrit. Blood viscosity are replaced by hematocrit that are one major factor of influencing blood viscosity. PTAs(pure-tone averages) are measured by hearing threshold averages level at 500Hz, 1000Hz, 2000Hz. Grades of PTAs(pure-tone averages) are divided three groups that are less then 10.0dB group, between 10.0-19.9dB group and excess 20.0dB. The results shows significant association among hematocrit, red cell number and hearing loss(age adjust by ANACOVA).

• Journal of the korean veterinary medical association
• /
• v.18 no.2
• /
• pp.67-69
• /
• 1982

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.11 no.2
• /
• pp.122-129
• /
• 2008

Purpose: Patients with chronic gastrointestinal disease are at risk for trace element deficiency due to impaired absorption and gastrointestinal loss. The aim of this study was to evaluate the trace element status of patients with gastrointestinal disease by blood and hair analysis, and to determine the usefulness of hair mineral analysis for diagnosing trace element deficiency not detected by a blood test. Methods: An analysis of hair minerals was performed and compared with blood mineral analysis in 13 patients with chronic gastrointestinal disease. The concentration of each element in the hair and blood was compared in the subgroups based on parenteral nutritional support or clinical symptoms. Results: Almost all patients had trace element deficiency. The trace elements deficient in the blood or hair analysis included zinc, selenium and copper. The hair zinc concentration was significantly lower in the group receiving parenteral nutritional support. The hair selenium concentration was statistically associated with the clinical symptoms of hair loss, brittle hair and loss of hair pigmentation. Conclusion: The results of this study suggest that patients with chronic gastrointestinal disease should receive adequate zinc and selenium replacement to avoid trace element deficiency especially when treated with long-term parenteral nutrition. Hair mineral analysis is useful as a complementary tool for the detection of a trace element deficiency.

• Electronics and Telecommunications Trends
• /
• v.30 no.2
• /
• pp.40-48
• /
• 2015

우리나라를 비롯한 선진국들의 고령화 추세와 맞물려 재택의료와 같이 의료기관과 전문인력이 배제된 현장에서 적용할 수 있는 의료행위에 대한 수요가 크게 증가할 것으로 예상된다. 이를 위한 다양한 검사와 진단방법이 개발되고 있는데, 주요 검사대상으로 사용되는 혈액의 전처리 과정은 매우 중요한 첫 단계이다. 전력이 공급되지 않는 상황에서 비전문가가 중대형 장비에 의존하지 않고 최소한의 시간에 혈액을 특정 검사 직전 단계까지 처리하는 방법에 대해 많은 연구가 진행되어 왔다. 본고는 현장의료에 있어서 혈액 전처리의 중요성과 필요성 및 이와 관련된 시장을 살펴보고, 특히 혈구 제거를 위해 현재까지 보고된 매우 폭넓고 다양한 방법 중 대표적인 국내외 사례들과 ETRI의 연구결과들을 소개한다.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2024.05a
• /
• pp.450-452
• /
• 2024

본 논문에서는 다양한 합병증의 원인인 형태 이상 적혈구로 인한 질환 진단의 정확도 및 오진율 감소를 위해 말초 혈액 도말 검사를 통한 혈액의 병리학적 이미지를 토대로 형태 이상 적혈구를 검출 및 계수하는 시스템을 구현하였다. 본 시스템은 혈액 분석 검사에 주로 사용되는 자동 혈구 분석기의 비용 및 인력, 시간의 부담을 줄이고, 수기법의 검출 소요시간 및 검사자의 주관적 진단 등 문제점을 개선시켜 단시간 내에 대량 분석을 할 수 있는 객관적인 진단 기구로 활용되어 정밀 의료 분야에 큰 기여를 할 수 있을 것으로 기대한다.

• Tuberculosis and Respiratory Diseases
• /
• v.42 no.4
• /
• pp.548-554
• /
• 1995

Background: Cardiogenic pulmonary edema increases nonspecific airway responsiveness in humans and animals. Increased extravascular lung water from overt pulmonary edema to subclinical interstitial edema is a common finding in patients with chronic renal failure. Several studies carried out to assess pulmonary function disturbances in this condition have documented a reduction in forced expiratory volume that usually reverses after hemodialysis, suggesting airway edema as the underlying mechanism. This interstitial edema may also lead to nonspecific bronchial hyperresponsiveness. We hypothesized that patients with chronic renal failure may present nonspecific bronchial hyperresponsiveness due to subclinical interstitial pulmonary edema. Methods: We studied 18 chronic renal failure undergoing regular hemodialysis 3 times a week(New York Heart Association Class II) without concomittent disease. These patients were checked pulmonary function test and metacholine provocation test before hemodialysis and same procedure was repeated if responsive, after hemodialysis. Results: 1) 12 out of 18 patients before hemodialysis were reactive in metacholine provocation test(66.7%) before hemodialysis. This airway hyperresponsiveness were decreased after hemodialysis. 2) Pulmonary function was improved after hemodialysis and change in $FEV_1$ was correlated with change in weight(r=-0.62, p<0.01). 3) There was a close correlation between log $PD_{20}$ and $FEF_{25}$, which is one of the variables of the peripheral airways(r=0.58, p<0.05). Conclusion: We speculated interstitial pulmonary edema may play a significant role in bronchial hyperresponsiveness and lung function impaired in patients with chronic renal failure.