• Journal of Acupuncture Research
• /
• v.28 no.1
• /
• pp.101-108
• /
• 2011

목적 : 신정격 자침이 당뇨군과 정상군의 혈관변화에 미치는 영향을 알아보기 위해 가속도맥파를 이용한 실험을 설계하였다. 방법 : 20명의 당뇨군과 20명의 정상군에서 신정격 자침 이전과 이후, 2회에 걸쳐서 Cardio Peri SA6000을 이용하여 가속도맥파를 측정하였다. 가속도맥파의 b/a, c/a, d/a 및 연령지수를 통해 혈관상태를 평가하였다. 결과 : 1. 당뇨군과 정상군의 신정격 자침 이전 가속도맥파 측정에서 당뇨군이 정상군보다 b/a값(p=0.000), 연령지수(AI)(p=0.000)는 유의하게 높았으며, c/a값(p=0.000), d/a값(p=0.000)은 유의하게 낮았다. 2. 당뇨군에서 신정격 자침 이후 가속도맥파의 b/a값(p=0.004), 연령지수(p=0.012)는 유의하게 낮아졌으며, c/a값(p=0.026)은 유의하게 높아졌다. 3. 정상군에서 신정격 자침 이후 가속도맥파의 b/a값(p=0.025)은 유의하게 낮아졌다. 결론 : 신정격 자침이 당뇨로 인해 유발된 혈관의 탄력도 감소 및 노화를 다소 회복시킬 수 있는 것으로 사료된다.

• Journal of Chest Surgery
• /
• v.35 no.4
• /
• pp.283-289
• /
• 2002

Backgrouds: It is almost universally accepted that occlusive vascular diseases are best managed by anatomical reconstruction. However, the mortality and the morbidity have limited this operation for patients with high operation risks. In these patients, palliative operations such as extra-anatomic bypass and lumbar sympathectomy, are accepted as useful treatment. Material and Method: A retrospective study was conducted in 38 patients who underwent palliative operations for occlusive vascular disease at Korea University Guro Hospital between 1996 and 2000. Mean age of the patients was 60.37 $\pm$ 17.65 years, and preoperative diagnoses were atherosclerosis in 32 patients, Buerger's disease in 4 patients, Raynaud's syndrome in 1 patient and SVC syndrome in 1 patient. Result: Extra-anatomic bypass(40procedures), lumbar sympathectomy(17), thromboembolectomy(7) and femoral artery graft interposition(1) were performed. Six patients were required reoperation due to graft flow failure or fistula. Three year primary patency rate of entire operations was 78.29 $\pm$ 8.81%, and the correlation between type of operation and patency rate was not statistically significant. Conclusion: Palliative operations for occlusive vascular disease are useful treatment in limited patients with high operation risks or limited life expectancy.

• Journal of the Institute of Electronics Engineers of Korea SC
• /
• v.41 no.5
• /
• pp.65-70
• /
• 2004

In this paper, we present a new methodology to analyze the characteristic of artery by using 4 channels photoplethysmograpy. The proposed parameter is a time difference of pulse transit time(PTT) between Pulse waves at finger site and at toe site. To verify the usefulness of the developed system volume pulse waves on 4 sites were measured simultaneously for total 51 normal subjects (male 26 and female 25) aged from 9 to 83 years old. And then correlations between the analysis parameters and age were evaluated by using linear regression analysis method. As the result of experiments, the change of parameter was found according to ages. The result of regression analysis about relationships between the parameter and ages for n=51, the coefficient of correlation of non-normalized data has 0.79770 in left side and 0.80599 in right side and the coefficient of correlation of normalized data by height has 0.81345 in left side and 0.81605 in right side.

• The Journal of the Society of Korean Medicine Diagnostics
• /
• v.12 no.1
• /
• pp.42-62
• /
• 2008

Objectives: It is well known that some parameters of the photoplethysmogram (PPG) acquired by time domain contour analysis can be used as markers of vascular aging. But the previous studies that have been performed for frequency domain analysis of the PPG to date have provided only restrictive and fragmentary information. The aim of the present investigation was to determine whether the harmonics extracted from the PPG using a fast Fourier transformation could be used as an index of vascular aging. Methods: The PPG was measured in 600 recruited subjects for 30 second durations, To grasp the gross age-related change of the PPG waveform, we grouped subjects according to gender and age and averaged the PPG signal of one pulse cycle. To calculate the conventional indices of vascular aging, we selected the 5-6 cycles of pulse that the baseline was relatively stable and then acquired the coordinates of the inflection points. For the frequency domain analysis we performed a power spectral analysis on the PPG signals for 30 seconds using a fast Fourier transformation and dissociated the harmonic components from the PPG signals. Results: A final number of 390 subjects (174 males and 216 females) were included in the statistical analysis. The normalized power of the harmonics decreased with age and on a logarithmic scale reduction of the normalized power in the third (r=-0.492, P<0.0001), fourth (r=-0.621, P<0.0001) and fifth harmonic (r=-0.487, P<0.0001) was prominent. From a multiple linear regression analysis, Stiffness index, reflection index and corrected up-stroke time influenced the normalized power of the harmonics on a logarithmic scale. Conclusions: The normalized harmonic power decreased with age in healthy subjects and may be less error prone due to the essential attributes of frequency domain analysis. Therefore, we expect that the normalized harmonic power density can be useful as a vascular aging marker.

• Journal of the Korean Arthroscopy Society
• /
• v.10 no.1
• /
• pp.91-94
• /
• 2006

Synovial hemangioma of the knee joint has been reported as a rare cause of pain, limitation of motion and hemarthrosis, often seen as an internal derangement of the knee. A 39-year-old woman presented with spontaneous hemarthrosis of the left knee joint and physical exam revealed a small painful mass adjacent to the medial side of the patella. Magnetic resonance imaging revealed an intra-articular tumor. Arthroscopic excision was performed and the histology was characteristic of hemangioma. Through this case, we discuss the diagnosis and treatment options for the synovial hemangioma of the knee.

• Journal of Chest Surgery
• /
• v.29 no.4
• /
• pp.454-457
• /
• 1996

The Incidence of synovial sarcoma Is very low but sarcoma Is a well-defined entity, which occurs primarily around large Joints and usually in association with tendon sheaths, bursae or the capsule. Recently we experienced a case of synovial sarcoma which invaded the right femoral vein of 433 5-year-old man. The tumor was widely excised incl ding the invaded femoral vein, and vein reconstruction was done using saphenous vein graft. The postoperative course was uneventful without intractable edema nor disability.

• The Korean Journal of Nuclear Medicine
• /
• v.27 no.2
• /
• pp.256-260
• /
• 1993

Thirteen patients received a coralline hydroxyapatite sphere as a buried integrated ocular implant after enucleation surgery. The implant was modified by multiple drillings, 1 mm in diameter, to the center of the sphere to allow more rapid host tissue ingrowth. $^{99m}Tc$-MDP planar and tomographic bone scintigraphies were performed at various intervals after implantation (from 100 to 742 days after operation) to assess vascularization of the implant. All patients showed hot uptakes in the implants. These patients underwent a secondary drilling for the final motility peg application. The confirmation of vascular ingrowth was done by inspection of bleeding at the time of bleeding at the time of drilling from the center of the implant. Bleeding from the drilled implant was noted in all patients. In cnclusion, hot uptake in the implanted ocular hydroxyapatite implant accurately reflect vascular ingrowth into the implant.

• Journal of The Korean Ophthalmological Society
• /
• v.59 no.11
• /
• pp.1030-1038
• /
• 2018

Purpose: To evaluate whether early visual acuity response at 4 weeks after the first intravitreal anti-vascular endothelial growth factor (VEGF) injection or 4 weeks after the third injection in neovascular age-related macular degeneration (nAMD) is associated with 12-month follow-up outcome. Methods: Thirty treatment-naive patients (30 eyes) with nAMD, treated with intravitreal anti-VEGF, were retrospectively included. Initially, all patients were injected at least three times for three consecutive months and followed up with a pro re nata regimen for at least 12 months. The relationship between 4 weeks after the first and third anti-VEGF injections in visual acuity response was explored, including the mean change from baseline in best-corrected visual acuity (BCVA). The mean change in BCVA was classified into three groups according to visual improvement: <1, 1-<3, or ${\geq}3$ logMAR line(s) in BCVA. The associations among baseline characteristics (gender, age, duration of symptoms, initial BCVA, central macular thickness, and intraocular pressure) and visual acuity responses 4 weeks after the first and third anti-VEGF injections were also assessed. Results: The proportions of eyes with <1, 1-<3, and ${\geq}3-line(s)$ improvement at 4 weeks after the first injection were 6 eyes (20%), 7 eyes (23.3%), and 17 eyes (56.6%), respectively. The proportions of eyes with <1, 1-<3, and ${\geq}3-line(s)$ improvement at 4 weeks after the third injection were 9 eyes (30%), 9 eyes (30%), and 12 eyes (40%), respectively. A BCVA response ${\geq}3-lines$ improvement at 4 weeks after the third injection showed significant associations with ${\geq}3-line(s)$ improvement and BCVA response at 12 months in multiple logistic and linear regression analyses (p = 0.04). Conclusions: In this study, BCVA response ${\geq}3-lines$ improvement at 4 weeks after the third injection showed a significant association with ${\geq}3-line(s)$ improvement and BCVA response at 12 months.

• Journal of Chest Surgery
• /
• v.30 no.12
• /
• pp.1190-1196
• /
• 1997

Between July 1994 and August 1995, 78 patients underwent coronary artery bypass graft at Seoul National University Hospital. Coronary angiogram was performed one year after coronary artery bypass graft in 49 patients(62.8%) for evaluation of the graft patency and analysis of the risk factors for graft occlusion. The patency rates of both the internal mammary artery and the radial artery grafts were 100% , although three internal mammary artery grafts(5.0%) were narrowed(string sign). And that of the saphenous vein grafts were 85.2%. Multivariate analysis for the preoperative, operative, and postoperative factors was done between the widely patent and the narrowed internal mammary artery graft groups, and between the patent and the occluded saphenous vein graft groups by the general linear models procedure. Patient's age($\geq$60 years), postoperative intraaortic balloon pump insertion, bleeding, and acute renal failure were found to be the significant risk factors for internal mammary artery graft narrowing, and coronary artery size(< 1.5 mm) was the significant risk factor for the saphenous vein graft occlusion (p<0.05) . This study confirms that the arterial graft is superior to the vein graft at one-year patency rate, and suggests the risk factors for graft occlusion during the first postoperative year. Knowledge of this study may provide a basis for estimating the risk factors for graft occlusion, and thereby modifying surgical strategy and postoperative surveillance.

• The Journal of the Korean bone and joint tumor society
• /
• v.16 no.2
• /
• pp.74-79
• /
• 2010

Purpose: To analyse the risk factors for recurrence of hemangiomas in extremities after surgical treatment and to compare with those of trunk. Materials and Methods: 120 cases of hemangioma with surgical treatments from June 1998 to September 2009 were analysed. 53 cases with surgical treatment on trunk in the same period were set to be the control group. We analyze several factors: age, location, site, size, histologic types and correlation between recurrence and each risk factor using logistic regression analysis. Results: Recurrence rate was 11.7% in extremities and 9.4% in trunk. There were no correlation between recurrence and age, site, size, histologic type. But, there was stastically significant correlation between recurrence rate and location, especially hand, forearm, feet in extremities and head and neck in trunk. Conclusion: Recurrence after surgical treatment of hemangioma is highly prevalent in anatomical location such as, hand, foot and forearm those are difficult to achieve complete resection because of close to neurovascular structures. Careful observation should be needed owing to incomplete resection can occurs recurrence.