• 한국IT서비스학회지
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• 제19권4호
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• pp.49-61
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• 2020

Prior studies on technology predictions attempted to predict the emergence and spread of emerging technologies through the analysis of correlations and changes between data using objective data such as patents and research papers. Most of the previous studies predicted future technologies only from the viewpoint of technology development. Therefore, this study intends to conduct technical forecasting from the perspective of the consumer by using keyword search frequency of search portals such as NAVER before and after the introduction of emerging technologies. In this study, we analyzed healthcare technologies into three types : measurement technology, platform technology, and remote service technology. And for the keyword analysis on the healthcare, we converted the classification of technology perspective into the keyword classification of consumer perspective. (Blood pressure and blood sugar, healthcare diagnosis, appointment and prescription, and remote diagnosis and prescription) Naver Trend is used to analyze keyword trends from a consumer perspective. We also used the ARIMA model as a technology prediction model. Analyzing the search frequency (Naver trend) over 44 months, the final ARIMA models that can predict three types of healthcare technology keyword trends were estimated as "ARIMA (1,2,1) (1,0,0)", "ARIMA (0,1,0) (1,0,0)", "ARIMA (1,1,0) (0,0,0)". In addition, it was confirmed that the values predicted by the time series prediction model and the actual values for 44 months were moving in almost similar patterns in all intervals. Therefore, we can confirm that this time series prediction model for healthcare technology is very suitable.

• 한국정보시스템학회지:정보시스템연구
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• 제28권3호
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• pp.159-202
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• 2019

Purpose The purpose of this study is to explain users' wearable healthcare device adoption using performance expectancy, effort expectancy, the hedonic motivation and price value of UTAUT2, and to identify the causal relationship between intention to use wearable healthcare device and innovation resistance formed by perceived risks. Design/methodology/approach The research model proposed in this study is based on UTAUT2(Extended Unified Theory of Acceptance and Use of Technology) and MIR(Model of Innovation Resistance). In specific, performance expectancy, effort expectancy, hedonic motivation and price value of UTAUT2 and innovation resistance formed by perceived risks of MIR are adopted in our research model. To validate the research model, we carry out the analysis of the survey data using Smart PLS 3.0 to test the hypotheses. Findings According to the empirical analysis results, this study confirms that the performance expectancy, effort expectancy, hedonic motivation, and price value have significant effects on the intention to use wearable healthcare devices. It also finds that perceived risk affects innovation resistance and in turn, innovation resistance affects the intention to use wearable healthcare devices.

• 한국음향학회지
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• 제42권5호
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• pp.412-421
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• 2023

초음파 뇌 자극술을 통하여 뇌 심부의 국소 지역에 있는 뇌 세포의 활성화를 유도할 수 있으며, 이를 통하여 저하된 뇌 기능을 치료하는데 효과가 있음이 보고되어 왔다. 반면, 초음파 자극의 종류에 따라 신경 변조의 효율과 방향이 달라질 수 있음이 알려져 있어, 적절한 초음파 자극의 종류를 확립하는 연구가 중요하다. 따라서, 본 논문에서는 이를 효과적으로 최적화 하기 위해 세포 배양시 사용되는 커버슬립 기반의 초음파 변환자를 제안하고자 한다. 균일한 초음파 자극을 전도하기 위해서 폴리머 압전소자(Poly-vinylidene fluoride-trifluorethylene, PVDF-TrFE)를 스핀 코팅하고 패를린 절연층을 상단에 적층시켜 음압 출력을 극대화 시켰다. 개발된 초음파 변환자 융합 커버슬립은 초음파자극기 표면에 배양된 수십개의 신경세포에 균일하고 정확한 초음파 자극을 전달 할 수 있고, 자극에 따른 세포의 반응을 형광 현미경으로 실시간 관찰 가능하다. 따라서, 동일한 초음파 자극에 대한 세포의 반응 신호를 최대 수십개 세포로부터 동시에 획득 가능하므로, 반응 신호를 평균 한다면 낮은 강도의 초음파 자극에 따른 뇌 세포의 미세한 반응을 검출할 수 있을 뿐만 아니라, 초음파 변환자와 물의 표면 등에서 발생하는 정현파에 의한 자극의 왜곡 현상을 줄일 수 있어서 사용자가 원하는 초음파 자극을 정확하게 세포로 전달 가능하다. 이렇게 개발된 초음파 변환자를 통해 변환자 표면에 배양된 별세포에서 6 MHz, 0.2 MPa의 저강도 초음파 자극에 의해 유도된 칼슘 반응을 성공적으로 관찰할 수 있었다.

• Journal of Nutrition and Health
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• 제56권3호
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• pp.231-246
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• 2023

본 연구에서는 MIA로 골관절염을 유도한 SD 흰쥐에서 인도산 보스웰리아 검레진을 주정 추출 후, 헥산으로 지방 제거 공정을 추가하여 제조한 보스웰리아 검레진 추출물인 FJH-UBS의 항골관절염 효능을 평가하기 위해 실시하였다. FJH-UBS는 40 또는 80 mg/kg BW/day 용량으로 5주간 경구투여하였고, FJH-UBS를 2주간 투여 후 MIA (3 mg/50 µL/rat)를 무릎 관절강 내에 주사하여 골관절염을 유도하였다. MIA 유도 골관절염 동물모델에서 FJH-UBS는 무릎 관절의 부종을 감소시키고 연골의 분해를 억제하였으며, 연골 내 type II collagen과 aggrecan 발현을 증가시켰다. FJH-UBS (80 mg/kg BW/day)는 혈청 내 PGE2, LTB4, IL-1β, 및 IL-6 함량을 감소시켰고, MMP-13 함량을 감소시켰다. FJH-UBS (80 mg/kg BW/day)는 연골 활막 내 iNOS, COX-2, 5-LOX, IL-1β, IL-6 및 TNF-α 발현을 감소시켰고, MMP-2, MMP-9 및 MMP-13 발현을 감소시켰다. 이 결과는 FJH-UBS가 염증매개물질과 염증성 cytokine의 발현감소를 통해 염증 반응을 억제하고, MMPs의 발현을 억제하여 연골 기질의 분해를 억제함으로서 항골관절염 효능을 나타냄을 의미하며 이는 관절 및 연골 건강 개선 기능성 원료로 FJH-UBS의 활용 가능성을 제시한다.

• 동서간호학연구지
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• 제25권2호
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• pp.174-182
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• 2019

Purpose: The purposes of this study were to develop a drum club activities program for soldiers and to explore the effects of the program on the mental health of soldiers. Methods: This study used one group pretest-posttest design. A drum club activities program for soldiers was offered for 12 weeks with each session of 2 hours. A total of 33 participants were recruited but eighteen participants who did not participate in sessions of the program more than 3 times were dropped out of the study. Finally, data from 15 participants were analyzed using the SPSS 22.0 program. Mental health status (stress, anxiety and aggression) was measured by Vibraimage technology. Vibraimage technology is a useful and objective method to identify the human psychophysiological state by analyzing the movement of various frequencies and amplitudes of head motion and face image using camera. Results: There is statistically significant difference in anxiety (Z=-3.12, p<.001) after implementation of the program. However, there was no statistically significant difference in stress and aggression. Conclusion: The results indicate that the drum club activities program was effective in decreasing anxiety in soldiers. The drum club activities program can be considered as a possible nursing intervention strategy to reduce anxiety for soldiers.

• 한국약용작물학회지
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• 제28권6호
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• pp.435-444
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• 2020

Background: As the Positive List System (PLS) is implemented in broad application to agricultural products, attention to the correct use of pesticides is also needed in the production of mulberry leaves and fruit. In this regard, three types of pesticides against mulberry popcorn disease were applied 2 - 3 times both in the field and greenhouses to prepare safety standards. Residual pesticide analysis was conducted on mulberry fruits and leaves. Methods and results: Three pesticieds, thiophanate-methyl, thiophanate-methyl·triflumizole and fluopyram registered as PLS pesticides for mulberry popcorn disease, were sprayed in the Wanju and in Buan regions, after which residual pesticide analysis was conducted using high-performance liquid chromatography (HPLC). As three pesticieds were either undetected or below the permissible level in mulberry fruit, demonstrating that they were suitable for safe spraying. However, 5.6 mg/kg of thiophanate-methyl was detected in the greenhouse after three application, which was slightly above maximum residue limit (MRL). Furthermore the level of thiophanate-methyl·triflumizole was higher than 0.2 mg/kg ("Gwasang No. 2" variety, spraying twice) or similar to 0.09 mg/kg ("Daesim" variety, spraying thrice) the permissible level (0.1T mg/kg) as the thiophanate-methyl was detected in mulberry leaves in the greenhouse. Conclusions: The spraying frequency for controlling mulberry popcorn disease in greenhouses should be limited to two times or less, especially when mulberry leaves are treated with thiophanate-methyl·triflumizole careful consideration is required if the leaves are to be used as food materials.

• 한국환경보건학회지
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• 제48권2호
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• pp.96-105
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• 2022

Background: Pyrethroid insecticides account for more than 30% of the global insecticide market and are frequently used in agricultural settings and residential and public pest control among the general population. While several animal studies have suggested that exposure to pyrethroids can alter glucose homeostasis, there is only limited evidence of the association between environmental pyrethroid exposure and diabetes in humans. Objectives: This study aimed to report environmental 3-phenoxybenzoic acid (3-PBA) concentrations in urine and evaluate its association with the risk of diabetes in Korean adults. Methods: We analyzed data from the Korean National Environmental Health Survey (KoNEHS) Cycle 2 (2012~2014) and Cycle 3 (2015~2017). A total of 10,123 participants aged ≥19 years were included. Multiple logistic regressions were used to calculate the odds ratios (ORs) for diabetes according to log-transformed urinary 3-PBA levels. We also evaluated age, sex, education, monthly income, marital status, alcohol drinking, physical activity, urinary cotinine, body mass index, and sampling season as potential effect modifiers of these associations. Results: After adjusting for all the covariates, we found significant dose-response relationships between urinary 3-PBA as quartile and the prevalence of diabetes in pooled data of KoNEHS Cycles 2 and 3. In subgroup analyses, the adverse effects of pyrethroid exposure on diabetes were significantly stronger among those aged 19~39 years (p-interaction<0.001) and those who consumed high levels of cotinine (p-interaction=0.020). Conclusions: Our findings highlight the potential diabetes risk of environmental exposure to pyrethroids and should be confirmed in large prospective studies in different populations in the future.

• 한국정보시스템학회지:정보시스템연구
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• 제25권2호
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• pp.27-50
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• 2016

Purpose The purpose of this study is to examine the effect of the acceptance intention towards healthcare wearable device in Korea. Specifically, this study attempted to identify the relationships among the acceptance intention towards healthcare wearable device, technical characteristics and user's personal characteristic based on UTAUT(Unified Theory of Acceptance and Use of Technology) model. Design/methodology/approach For this purpose of research, we conducted against consumers who use the wearable devices and we collected data from 219 wearable device users. The analyses were conducted using SPSS and AMOS19.0 which is powerful structural equation modeling (SEM) software. Findings The main findings are as followed; First, functional diversity, wearability, trend sensitivity and health perception are significantly related to performance expectancy, while visual aesthetic and enjoyment are not significantly related. Second, performance expectancy and effort expectancy are significantly related to acceptance intention towards healthcare wearable device. Third, effort expectancy is significantly related to performance expectancy.

• 한국정보통신학회논문지
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• 제13권2호
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• pp.425-430
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• 2009

의료분야에서 많은 정보가 디지털화 되고 있으며 개인의 건강에 대한 관심은 점점 높아지고 있다. 이에 발맞추어 U-health 시스템을 구축하기 위한 고속의 개인용 헬스케어 모니터링 플랫폼이 요구된다. 본 논문에서는 이러한 요구를 충족시키기 위해 고속의 ARM11 기반의 최신 프로세서인 S3C6400 CPU를 이용한 플랫폼 구현에 관한 연구를 진행하였다. 더불어 무선의 의료용 데이터 전송을 위해 802.11기반의 무선 랜을 이용한 네트워크 시스템 환경을 구축하였다.

• 한국염색가공학회:학술대회논문집
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• 한국염색가공학회 2011년도 제45차 학술발표회
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• pp.55-55
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• 2011

국내의 등산용 아웃도어 제품의 경우, 기능성인 투습도와 내수압만을 증대시키려는 연구가 주류를 이루고 있었다. 하지만, 실제 등산용 아웃도어의 경우 산악지형인 고지대에서 사용시간이 많으므로, 이에 따른 장시간의 직접적인 태양광 노출로 인한 인체에 치명적인 영향을 야기시키고 있지만, 인체 보호용 헬스케어 아웃도어 제품에 대한 연구는 미흡한 실정이다. 태양광은 자외선 2.5%, 가시광선 51.5%, 적외선 46.0%의 광량 비율을 가지고 있으며, 이 중 자외선은 광량은 적지만 에너지적으로 높아 유기물 분해 및 열화를 일으킨다. 이러한 자외선을 차단하기위해 아웃도어 의류에서는 유무기하이브리드 소재를 표면에 코팅시키게 되며, 기능성 코팅액내에 함유되어 있는 나노분말의 경우 이산화티타늄($TiO_2$), 산화세륨(CeO), 산화아연(ZnO), 삼산화텅스텐($WO_3$), 산화마그네슘(MgO) 등이 주로 사용되어 진다. 본 연구에서는 자외선 흡수소재로 나노산화아연분말을 이용하여, 그 입도 및 코팅용 희석 용매내의 분산성을 확인하고, 함유량을 달리한 코팅 수지를 제조하여, 코팅시편 제조 후 그 특성을 비교/분석하여 자외선 차단 효과를 확인하고자 한다.