• Title/Summary/Keyword: 헤모글로빈 농도

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Fire Patterns Based on the Hb-CO Concentration (헤모글로빈-일산화탄소 농도에 따른 연소형태)

  • Choi, Seung-Bok;Oh, Bu-Yeol;Choi, Don-Mook
    • Proceedings of the Korea Institute of Fire Science and Engineering Conference
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    • 2011.11a
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    • pp.373-377
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    • 2011
  • Fire patterns have been used to determine the origin and cause of fires in every setting imaginable. However, it is very difficult to identify fire patterns from the fire-damaged remains of a devastated structure. If someone was killed by the fire, it is possible to identify fire patterns by analyzing the concentration of carbon monoxide-hemoglobin in the body of deceased as well as the pace of the fire. For example, a low level of carbon monoxide-hemoglobin in the body of the dead indicates a rapid fire with accelerants and the death was caused by severe heat and thick toxic fumes. However, a high level of carbon monoxide-hemoglobin in the body of the dead demonstrates that the fire was slow and/or there was a flameless form of combustion. Thus, this study identifies fire patterns through analyzing the level of carbon monoxide-hemoglobin concentration on the dead from the fire.

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Association between Chronic Obstructive Pulmonary Disease and Hemoglobin Concentration in the Elderly: Based on National Health and Nutrition Survey (국민건강영양조사 자료를 이용한 노인의 만성폐쇄성폐질환과 헤모글로빈 농도의 상관관계)

  • Cho, Hyoung Jun;Huh, Yool-Gang;Kim, Dae hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.11
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    • pp.157-163
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    • 2019
  • This study determines the difference in prevalence of anemia and hemoglobin concentration between chronic obstructive pulmonary disease (COPD) and control groups in the elderly. Moreover, this study also examines the prevalence of anemia and hemoglobin concentration according to the severity of COPD in the elderly. Medical records of 8150 participants who answered the 7th National Health and Nutritional Survey conducted in 2016 were reviewed, and a total of 694 participants was included in the analysis. Participants were classified into two groups: COPD and control groups. Laboratory studies on hemoglobin, hematocrit, red blood cell concentration and prevalence of anemia were collected. Subgroup analysis was also conducted according to the severity of COPD. No significant differences were determined for the prevalence of anemia and hemoglobin concentration between both groups. Hemoglobin concentration was significantly higher in the COPD group. Although not statistically significant, there was a tendency for decrease in the prevalence of anemia and increase in the hemoglobin concentration as the severity of COPD increased. Our findings present specific data about the prevalence of anemia and hemoglobin concentration in elderly patients with COPD. Hence, we propose that occurrence of anemia in elderly patients with COPD requires further evaluation of the causes.

Association of Hemoglobin Levels and Cognitive Function in Alzheimer's Disease and Mild Cognitive Impairment (알츠하이머병과 경도인지장애에서 헤모글로빈 농도와 인지기능과의 연관성)

  • Park, Joon Kyung;Lee, Kang Joon;Kim, Hyun
    • Korean Journal of Psychosomatic Medicine
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    • v.24 no.1
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    • pp.94-101
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    • 2016
  • Objectives : Anemia is a common problem in the management of elderly patients. Recent studies reported that anemia was associated with cognitive impairment and Alzheimer's disease. This study was aimed to analyze the differences of hemoglobin levels in Korean patients with Alzheimer's disease(AD) dementia, mild cognitive impairment(MCI), and healthy controls. Furthermore, the study also examined if any association between hemoglobin levels and cognitive functions existed. Methods : A total of 116 Korean elderly adults were participated in this study(mean age 74.67 years ; 60.3% female). The Korean version of the Mini-Mental State Examination(MMSE-K), Clinical Dementia Rating(CDR) and Global Deterioration Scale(GDS) were applied to all subjects. Hematological and related blood chemistry values were investigated. Results : We found that patients with AD dementia had significantly lower hemoglobin and hematocrit levels than MCI subjects and healthy control group. The hemoglobin levels showed a positive correlation with MMSE-K and negative correlation with CDR, GDS. Conclusions : Among Korean elderly, low hemoglobin level is associated with a cognitive impairment. This study indicates that AD is associated with anemia, and low hemoglobin levels may contribute to potentially useful clinical markers of AD. The risk factor for dementia needs to be confirmed by prospective longitudinal studies in a larger group of patients.

Generation of Carbon Monoxide from Saccharides (당류 중에서 일산화탄소의 발생에 관한 연구)

  • Kim, Nam Yee;Seo, Joong Seok;Park, Sung Woo
    • Analytical Science and Technology
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    • v.14 no.6
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    • pp.522-529
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    • 2001
  • Carbon monoxide was generated when the saccharides which contained aldehyde group were added to alkali solution (NaOH solution) at $25^{\circ}C$ or $40^{\circ}C$. When the milk was added to 1.0 M NaOH solution at $25^{\circ}C$ and to 0.01 M NaOH solution at $40^{\circ}C$, carbon monoxide was generated. The carbon monoxide gas which was generated by 20 mL of 0.1 M lactose or 0.1 M xylose and 2 mL of 1.0 M NaOH solution at $50^{\circ}C$ for 2days was bubbled through 2 mL of fresh blood. The carboxyhemoglobin concentrations of both conditions were 31%. However, when the carbon monoxide gas which was generated by 30 mL of milk and 2 mL of 1.0 M NaOH at $50^{\circ}C$ for 2days or 3days was bubbled through 2 mL of fresh blood, the carboxyhemoglobin concentration was 32% or 42% respectively.

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Influence of Other Blood Components in Predicting Glucose Concentration using Design of Experiment (실험계획 법에 의한 혈중 글루코즈 측정 시 타 성분의 영향 분석)

  • 김연주;윤길원;전계진
    • Journal of Biomedical Engineering Research
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    • v.22 no.6
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    • pp.497-502
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    • 2001
  • Influence of other blond components on measuring glucose concentration was analyzed B)food phantom containing five major components was made. The prediction model was developed based on the measurement of absorption spectra including the first overtone glucose band, i.e.. 1500 ∼ 1850 nm. The concentrations were Predicted using the Partial least squares regression. Factor analysis based on Design of Experiment was Performed to study the influence of other components in predicting glucose concentration. Triglyceride does not influence. Albumin and globulin haute minor effects. However, hemoglobin showed substantial response and the compensation of hemoglobin concentration appears to be required for the model of glucose measurement.

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Ferritin and hemoglobin level of korean according to vitamin D state: The Korean National Health and Nutrition Examination Survey IV, V (2008~2012) (한국인의 비타민 D 수준에 따른 페리틴, 헤모글로빈 농도: 제4기, 제5기 (2008~2012) 국민건강영양조사)

  • Park, Juwon;Bae, Eun Jin;Lee, Taeck-hyun;Jin, Woo Sung;Choi, Hyunhee;Yang, Jeong Sook;Hong, Ji Eun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.9
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    • pp.57-67
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    • 2016
  • This study is designed to investigate the differences of ferritin and hemoglobin levels according to the vitamin D state in 23577 Korean adult subjects by using data from the Korea National Health and Nutrition Examination Survey IV, V. Ferritin and hemoglobin levels are analyzed based on the quintile of vitamin D levels by a generalized linear model. The results of analysis showed that there was a relationship between vitamin D state and hemoglobin levels in females in the reproductive status group (p<0.001). In case of ferritin, there was a relationship with vitamin D state in females in reproductive status group (p<0.001) and males under 65 years old group (p<0.05). Within the male group, high ferritin correlated with low vitamin D state; but in the female group, high ferritin correlated with high vitamin D state. Therefore, it is possible for the ferritin level to be affected by vitamin D state in females in reproductive status group and males under 65 years old group.

Spectral Analysis for Non-Invasive Total Hemoglobin Measurement in the Region from 400 to 2500nm (총헤모글로빈 농도를 비침습적으로 측정하기 위한 400-2500nm 대역의 흡수 스펙트럼 분석)

  • Jeon, Kye-Jin;Kim, Yoen-Joo;Kim, Su-Jin;Kim, Hong-Sig;Yoon, Gil-Won
    • Journal of Sensor Science and Technology
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    • v.10 no.6
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    • pp.273-278
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    • 2001
  • Absorption spectra of blood components have been measured for the purpose of predicting the total hemoglobin concentration. We obtained absorption spectra of major blood components from the visible to near-infrared of $400{\sim}2500nm$ region. In the near-infrared, water is the main absorbing constituent. The amount of water in the sample cell varies depending on the volume of solute concentration(water displacement). We acquired water-compensated spectra by considering the variation of water volume depending on the variation of analyze concentration. Those spectra show inherent absorption peaks of analyzes and linearity with respect to concentration. We selected wavelengths for non-invasive measurement of hemoglobin concentration considering the scattering effect of tissue and the interference of other blood components.

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Effects of Aspirin on Nitrite Toxicity in Cultured Eel (Anguilla japonica) (양식 뱀장어 (Anguilla japonica)의 아질산 독성에 미치는 aspirin의 투여 효과)

  • Kim, Dong-Wan;Koo, Jae-Geun;Park, Sung -Woo
    • Journal of fish pathology
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    • v.20 no.3
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    • pp.291-297
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    • 2007
  • The effect of aspirin on the recovery of nitrite-induced methemoglobinemia in cultured eels (Anguilla japonica) was studied. Methemoglobinemia was induced by exposing eels to nitrite (120 ㎎ NO2-N/ℓ) for 24 hr. The nitrite exposed eels were bathed in 20 ppm aspirin solution (Aspirin), 0.8 % NaCl solution (NaCl), 20 ppm aspirin plus 0.8% NaCl solution (NaCl + Aspirin) and 50% nitrite free water(control) for 24 hr to recover from nitrite toxicity. Peripheral blood was taken from the arterious bulb from all groups to analyse hematocrit value, hemoglobin concentration, and nitrite concentration of the blood. Histopathological features of gill were also observed. Aspirin and control groups were more effective than NaCl and NaCl + Aspirin groups in recovery of hematocrit value and hemoglobin concentration, methemoglobin rate and nitrite concentration. The histopathological features on the gill of aspirin group were similar to those of normal eels, but other groups showed focal hyperemia in the lamellar carpillaries, epithelial hyperplasia. These results suggested that aspirin was very effective to recover from methemoglobinemia in nitrite-induced cultured eels.

Anti-hyperglycemic Effect of Cortex Mori radicis in db/db Mice (db/db 마우스에서 상백피의 혈당강하효과)

  • Kim, Youn-Young;Choue, Ryo-Won;Chung, Sung-Hyun;Koo, Sung-Ja
    • Korean Journal of Food Science and Technology
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    • v.31 no.4
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    • pp.1057-1064
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    • 1999
  • Cortex Mori radicis has been used in the treatment of diabetes mellitus. In this study, the antihyperglycemic effect of Cortex Mori radicis was observed in obese diabetic mice(C57BLKsJ db/db). Cold water extract of Cortex Mori radicis was supplied in tab water(500, 1000 mg/kg/day) with normal chow for 5 weeks. Food intake and body weight gain were decreased significantly in experimental group. Also experimental group exhibited lower fasting serum glucose level when compaired to control group. Hb Alc level and triglyceride level were lowered in a dose-dependent manner. The activity of small intestinal disaccharidases was decreased at most segments. In conclusion, Cortex Mori radicis has anti-obesity effect to reduce food intake and body weight gain. And it is able to decrease the activity of small intestinal disaccharides and thus it can reduce serum glucose level and triglyceride level.

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