• Journal of the Korea Organic Resources Recycling Association
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• v.15 no.1
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• pp.123-133
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• 2007

The presence of antibiotics in the wastewater from livestock farm due to its over-application should be concerned because they could change microbial ecology, increase the proliferation of antibiotic resistant pathogens, provoke toxic effect on aquatic species. In addition, these antibiotics can cause negative effect on the performance of biological wastewater treatment due to its antibacterial properties. In this study, our aim is to evaluate the effect of some common used antibiotic in Korea piggery farm such as oxytetracycline (OTC) to nitrification efficiency as well as organic compounds removal rate in biological system for treating piggery wastwater. The experiment was conducted in aeration batch reactor and lab-scale $A_2/O$(Anoxic-Anoxic-Oxic) system. From this study, it would be suggested that the piggery wastewater characterization should be examined in order to assess the fraction of common used antibiotics. The alternative treatment processes for piggery wastewater having high-strength antibiotics might be suggested in the future work.

• Journal of the korean veterinary medical association
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• v.42 no.7
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• pp.599-605
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• 2006

‘국가항생제내성안전관리사업’을 총괄하고 있는 식약청은 수산용 항생제 사용이 인체에 미치는 영향을 평가하고 인체 위해를 최소화하기 위한 국제 전략을 수립하고자, 관련 국제기구인 FAO/WHO/OIE/Codex와 공동으로 2006년 6월13일부터 6월16일까지 제3차 국제전문가 회의(Joint FAO/WHO/OIE Expert Consultation on Antimicrobial Use in Aquaculture and Antimicrobial Resistance)를 개최하였다고 밝혔다. 이번 전문가 회의는 항생제내성에 대한 제1차 Geneva, 제2차 Oslo 회의에 이어 아시아에서는 처음으로 Seoul (식약청)에서 개최되었다.

• Journal of Food Hygiene and Safety
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• v.38 no.4
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• pp.193-201
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• 2023

Antimicrobials in human medicine are classified by The World Health Organization (WHO) into three groups: critically important antimicrobials (CIA), highly important antimicrobials (HIA), and important antimicrobials (IA). CIA are antibiotic classes that satisfy two main criteria: that they are the sole or the only available limited therapeutic option to effectively treat severe bacterial infections in humans (Criterion 1), and infections where bacteria are transmitted to humans from non-human sources or have the potential to acquire resistance genes from non-human sources (Criterion 2). WHO emphasizes the need for cautious and responsible use of the CIA to mitigate risk and safeguard human health. Specific antimicrobials within the CIA with a high priority for management are reclassified as "highest priority critically important antimicrobials (HP-CIA)" and include the 3^rd generation of cephalosporins and the next generation of macrolides, quinolones, glycopeptides, and polymyxins. The CIA list is the scientific basis for risk assessment and risk management policies that warrant using antimicrobials to reduce antimicrobial resistance in several countries. In addition, the CIA list ensures food safety in the food industry, including for the popular food chain companies McDonald's and KFC. The continuous update of the CIA list reflects the advancement in research and emerging future challenges. Thus, active and deliberate evaluation of antimicrobial resistance and the construction of a list that reflects the specific circumstances of a country are essential to safeguarding food security.

• Journal of the korean veterinary medical association
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• v.41 no.4
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• pp.337-355
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• 2005

• Monthly Korean Chicken
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• v.16 no.4
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• pp.56-59
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• 2010

• KOREAN POULTRY JOURNAL
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• v.31 no.5 s.355
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• pp.119-122
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• 1999

• Childhood Kidney Diseases
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• v.14 no.2
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• pp.203-209
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• 2010

Purpose : It has been a common medical practice to use prophylactic antibiotics to prevent recurrent urinary tract infections (UTI) in high risk situations such as urinary tract obstruction, vesicoureteral reflux, neurogenic bladder, or urinary stones. But sometimes, we meet difficult situation of breakthrough infections (BI) which might cause new or progressive renal scarring. The clinical characteristics of children contracting breakthrough UTI experienced in a single center were studied. Methods : The study was done retrospectively through medical records of 150 pediatric patients who had been cared in pediatric and urologic clinics of Pusan National University Hospital from Jan. 2001 till June 2006 and had prophylactic antibiotics to prevent recurrent UTI. Results : The starting age of prophylactic antibiotics of 150 patient was 1-76 months, and median age was 5 months. The BI developed 61 times in 43 patients (28.7%), 1.5 times per 100 patient-months. The BI occurred more frequently in patients with higher grade of VUR, and in the cases with abnormal DMSA scan. Co-trimoxazole was more effective than 2nd and 3rd generation cephalosporins to prevent UTI. The distribution of causative organisms was more diverse than usual UTI. The causative organisms were sensitive to the antibiotics used for prophylaxis in 29.5%, and resistant in 59.1%. After experience of BI, 40 percents of patients went to the surgical treatment including endoscopic injection of Deflux, 35% to new antibiotics for prophylaxis, 26% remain on the same antibiotics as the previous one. Conclusion : Based on our study results, preexisting renal scar might be one of the factors which should be considered in favor of early surgical interventions of VUR. Poor compliance and wrong selection of antibiotics such as cephalosporins are important underlying causes of breakthrough UTIs.

• Korean Journal of Poultry Science
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• v.36 no.3
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• pp.223-229
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• 2009

The objective of this study was to investigate the effect of the supplementation of antibiotics on meat quality grade of broiler carcasses under the Korean meat grading system. A total of 34,000 broiler carcasses, which were randomly selected 100 broilers from each farm in 340 broiler farms (305 farms with antibiotics; 35 farms without antibiotics), were used in this study. Average daily weight gain of broilers was not significantly affected by the use of antibiotics. The ratio of quality grade A was higher in the broiler carcasses from the farms with antibiotics supplementation (78.87%) than those without antibiotics (73.46%, P<0.05). The numbers of carcass defects, which are down-grade factors of meat grading system, were much higher in the broiler carcasses produced from the farms without antibiotics supplementation when compared with those with antibiotics. In particular, the incidence of the carcass defect on conformation was approximately 1.8 times higher in the carcasses from the farms without antibiotics supplementation than those with antibiotics, which showed the highest negative correlation with quality grade A. Therefore, the improvement of farm management system, the use of antibiotics alternatives from natural products, and a proper incentive should be considered in various ways to encourage farmers to reduce antibiotics usage in their farm and earn consumers' trust for antibiotics-free products.

• 대한임상약리학회:학술대회논문집
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• 1997.12a
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• pp.40-40
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• 1997

• Journal of the korean veterinary medical association
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• v.46 no.9
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• pp.805-815
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• 2010

본 원고에서는 소에서 항셍제가 주로 투여되는 대표적인 질병인 패혈증, 송아지설사, 관절염, 발질병, 폐렴, 자궁내막염, 유방염 중 유방염을 제외한 6가지 질병에 대해 적정한 항생제 사용에 대해 살펴보기로 한다.