• Title/Summary/Keyword: 한국 제4기학회

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Organic Acidopathies as Etiologic Diseases of Developmental Delay in Korean Childhood and Adolescent Age Group (한국인 소아청소년기 발달지연의 원인질환으로서의 유기산대사이상질환)

  • Lee, Jong Yoon;Lee, Ye Seung;Choi, Joong Wan;Bae, Eun Joo;Park, Won Il;Oh, Phil Soo;Lee, Hong Jin
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.12 no.2
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    • pp.85-93
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    • 2012
  • Purpose: Developmental delay is caused by very diverse etiologic diseases. Most chronic disorders has some influence on development. Chronic or acute disorders of CNS are main etiologic diseases of developmental delay. Up to now, over 60 diseases are included in organic acidopathies and most of them causes acute or chronic recurrent CNS damage and developmental delay. We have done this study to find out the importance of organic acidopathies causing developmental delay in Korean childhood and adolescent patients. Method: Retrograde analysis for 738 patients with developmental delay whose clinical informations are available and have done urine organic acid analysis for 5 years period, between Jan. 1st 2007 to Dec. 31th 2011. Statistical analysis was done with Student's t test using SPSS. Result: Out of 738 patients, 340 patients (46.1%) showed abnormalities on urine organic acid analysis. The most frequent disease was mitochondrial respiratory chain disorders (MRCD) (253, 34.3%), followed by ketolytic defects(39, 5.3%), 3-hydroxyisobutyric aciduria (26, 3.5%), glutaric aciduria type II (8, 1.1%), pyruvate dehydrogenase deficiency (3, 0.4%), 3-methylglutaric aciduria (2, 0.3%), glutaric aciduria type I (2, 0.3%), ethylmalonic aciduria (1, 0.15%), methylmalonic aciduria (1, 0.15%), HMG-CoA lyase deficiency (1, 0.15%), 3-methylcrotonylglycinuria (1, 0.15%), fatty acid oxidation disorders(1, 0.15%) and FAOD (1, 0.15%). Conclusion: Mitochondrial disorders are most frequent etiologic disease on all age group, followed by ketolytic defects and various organic acidopathies. The number and diversities of organic acidopathies emphasize meticulous evaluation of basic routine laboratory examinations and organic acid analysis with initial sample on every developmental patient.

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Effects of Supplementary Multiple Probiotics or Single Probiotics on the Performance, Intestinal Microflora, Immune Response of Laying Hens and Broilers (혼합 또는 단일 생균제가 산란계와 육계의 생산성, 소장내 미생물 균총 및 면역 체계에 미치는 영향)

  • Kim, Chan-Ho;Woo, Kyung-Chun;Kim, Geun-Bae;Park, Yong-Ha;Paik, In-Kee
    • Korean Journal of Poultry Science
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    • v.37 no.1
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    • pp.51-62
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    • 2010
  • This study was conducted to investigate the effects of dietary supplementation of multiple probiotics on the performance, small intestinal microflora and immune response in laying hens and broilers. In Exp.1, a total of 800, 82 wk old Hy-line Brown$^{(R)}$ laying hens were assigned to one of the following five dietary treatment; Control, Antibiotics (avilamycin 6 ppm), Probiotics; PB-M (Micro-ferm$^{(R)}$ 0.2%), PB-L (Lacto-sacc$^{(R)}$ 0.1%), PB-Y (Y University probiotics 0.2%). Each treatment was replicated eight times with 20 birds in each replicate and two birds were housed in each cage. Twenty birds units were arranged according to completely randomized block design. Feeding trial lasted 6 wk under 16 h lighting regimen. The Exp. 2, was conducted with a total of 1,000 broilers chicks (Ross$^{(R)}$). They were divided into five treatments, same as those of Exp. 1. Birds were fed starter (0~3 wk) and grower (4~5 wk) diets. Each treatment was replicated four times with 50 birds per pen comprising of deep litter. In Exp. 1, egg production parameters, such as hen-day and hen-house egg production, egg weight, broken and soft shell egg production, feed intake and feed conversion were not significantly different among treatments. However, strength and thickness of eggshell were significantly (P<0.05) different. Among the probiotics, PB-Y showed the highest strength and thickness of eggshell. Eggshell color, egg yolk color and Haugh unit were not significantly influenced. In Exp. 2, overall weight gain (0~5 wk) and mortality were not significantly different among treatments. However, weight gain of birds from PB-Y treatment during starter (0~3 wk) was significantly lower than the birds from Control and Antibiotic treatment. During the whole period (0~5 wk), birds from Antibiotics treatment had higher feed intake and Production Index (PI) and lower feed conversion than birds from Control treatment. Probiotics treatments were not significantly different from the Control on feed intake and feed conversion. In Exp.1, there were significant (P<0.05) differences in leukocytes parameters, such as white blood cell (WBC), hetrophil (HE), lymphocytes (LY), monocyte (MO), eosinophil (EO) and stress index (SI; HE/LY) in the blood of layers. Birds from Antibiotics and probiotics treatments tended to increase these parameters. In Exp. 2, however, only SI was significantly (P<0.05) decreased in Antibiotics treatments. Concentration of serum immunoglobulin (IgG) were higher (P<0.05) in PB-M and PB-Y treatments when compared with Control treatment in Exp. 1. The population of E. coli significantly (P<0.05) decreased in birds from Antibiotics, PB-L and PB-Y treatments when compared with birds from Control treatment in Exp. 1. Metalbolizability of crude fat decreased significantly (P<0.05) in birds from probiotic treatments in Exp. 2. It was concluded that the response of probiotics on the productivity of layers and broilers were different. Probiotics increased strength and thickness of eggshell in layers, and decreased feed conversion and increased PI in broilers. Leukocytes and IgG tended to increase by supplementation of antibiotics and probiotics in layers. Intestinal E. coli tended to decrease in layers. Digestibility of crude fat of diet decreased in probiotics treatments broilers. Parameters of blood and microbial were more sensitive in layers than broilers.

A Study on the Establishment of Distribution and Logistics System in the unified Korea (통일한국의 유통물류체계 구축 연구)

  • Park, Chang-Ho;Kang, Sang-Gon
    • Journal of Korea Port Economic Association
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    • v.31 no.1
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    • pp.15-36
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    • 2015
  • The purpose of this paper is "A Study on the Establishment of Distribution and Logistics System in the unified Korea". The main conclusion of this paper are as follows : North and South Korea shall conjunctionally foster the exchange and cooperation area and operate the joint pilot project to combine distribution and logistics system. To solve the problems of the maritime affairs, Fisheries, and international logistics, the cooperative agreement between North and South Korea will be needed to protect and develop of shipping, aviation and shipbuilding industry. Unification of two Koreas must be prepared as stage by stage ; ${\cdot}$Stage1(preparation period) : initiation of peace area. ${\cdot}$Stage2(development period) : forming the exchange and cooperation area ${\cdot}$Stage3(settlement period) : establishing peace belt on border area. After the unification, two Koreas must plan and undertake the construction of the distribution and logistics infrastructures, establishment of SCM system through Network and the connection to China through railway and road Network.

Effect of Alachlor Herbicide and Transparent Polyethylene Film Mulching on Growth and Yield of Peanuts (Alachlor와 P.E. 피복(被覆)이 땅콩의 생육(生育)과 수량(收量)에 미치는 영향(影響))

  • Lee, S.S.;Kang, K.H.;Back, J.H.;Lee, K.H.;Jung, S.H.;Choi, D.W.
    • Korean Journal of Weed Science
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    • v.4 no.1
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    • pp.79-87
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    • 1984
  • Herbicidal effects of alachlor to peanuts were observed under different formulations (granule containing 5.0% a.i. and emulsifiable concentrate containing 43.7% a.i.) and levels (granule with 3 and 6kg/l0a and emulsion with 300㏄/l0a) with the transparent polyethylene (P.E.) film mulching. Formulations and levels of alachlor did not affect emergence ratio, time of emergence and flowering, and early growth of peanuts such as the number of leaves and branches, length of branches; and shoot dry weight at 20 and 40 days after planting, but early growth was enhanced by P.E. film mulching. At harvest, weed dry weight was positively correlated with length of branches, but negatively correlated with the number of branches and shoot dry weight. Acalyphu australis and Chenopodium album were not effectively controlled by the application of alachlor and growth of C. album was retarded under P.E. film mulching. Portulaca oleracea and Digitaria sanguinalis were effectively controlled by alachlor, but they were not affected by P.E. film mulching. At harvest, D. sanguinalis, A. australis, and Echinochloa crus galli were predominant weeds in all treatments; persistence of alachlor may not be long enough to control even sensitive weeds to alachlor such as D, sanguinalis in the field of peanuts of which canopy development was relatively slow. Weed dry weight at harvest was negatively correlated with the number of pods and grain yield of peanuts. Among the yield components only the number of nods per plant was positively correlated with grain yield. Hana weeding after July 1 increased grain yield of Peanuts even in alchlor applied plots.

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The Convergence Relationship between Oral Health Behavior and Quality of Life and Depression in Adult Men (성인 남성의 구강건강행위와 삶의 질 및 우울증상과의 융합적 관련성)

  • Yu, Ji-Su;Hwang, Su-Hyun
    • Journal of the Korea Convergence Society
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    • v.11 no.4
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    • pp.295-301
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    • 2020
  • This study is a secondary data analysis study to examine the relationship between oral health behaviors, quality of life, and depression in adult men using data of the first year (2016) of the 7th national health and nutrition examination survey. The analysis was conducted on 2,647 of above the age 19 in men. The data were analyzed using PASW Statistics 18.0. Results were positive correlation between the quality of life (EQ-5D) and oral health behavior (0.142, p <0.01), and a negative correlation with the depression (PHQ-9) (-0.347, p). <0.01). The higher the rate of oral health behavior, the higher the quality of life and the lower the depression. These findings suggest that the level of practice of oral health behavior is closely related to the quality of life and depression, this will be used as basic data for developing health policy for oral health and general health improvement for adult males.

The Effect of Subjective Body Type Recognition on Weight Change in Women with Normal BMI (체질 량 지수가 정상인 여성의 주관적 체형 인식이 체중변화에 미치는 영향)

  • Park, Seo-Yeon
    • Journal of the Korea Convergence Society
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    • v.9 no.4
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    • pp.313-320
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    • 2018
  • This study was conducted to establish the effects of subjective body-forming perception on weight-controlling behavior and weight loss, and to suggest the need for proper information and education. Using the data from the National Health and Nutrition Examination Survey conducted in the 6th period (2013-2015), 6,238 women aged 19 and over who have a body mass index of $18.5-25kg/m^2$ were analyzed. As a result, the higher the level of education and income level, the higher they were perceived to be obese, the more they chose to lose exercise and diet in order to lose weight across the board. The weight loss effort rate was higher in the obese body type recognition group, but the body weight type was the highest in the one year body weight change group (p < .001). As a result, subjective perception of body shape affected not only weight control behavior but also weight change (p < .001). Accordingly, it is necessary to have a systematic education on healthy weight-controlling behaviors, proper body image, and healthy body type recognition.

A study of a plan for better curing methods through a reseach for a field of construction work (동절기 콘크리트 양생방법의 현장 실태조사 및 개선방안에 관한 연구)

  • Park Sung-June;Moon Hyung-Soo;Kim Chang-Duk
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • autumn
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    • pp.379-382
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    • 2003
  • Construction concrete needs to maintain suitable environment which contains temperature and humidity etc. Then concrete shows own strength. The environment is not regular and contains many variables. Especially the climate element occupies many parts of variables. We have the climate environment which goes down to $-4^{\circ}C$. The factor that obstruct to construction is the failure at a construction progress. But it must be processed to be scheduled. Therefore we have to do the special care for factor of climate that obstruct to construction. We must make assurance doubly sure at the quality of concrete. We need maintenance of temperature and humidity for the hardening until the requirement period after a concrete pured in. We must do the care of curing sufficiently not to take the influence of injurious activity. This causes strength of concrete. Specific method of curing is according to each situation which is environment element. We wish to analyze curing course in construction of concrete at the paper. Also we wish to predict the problem as to consider curing and suggest the improvement plan through the paper.

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Convergence analysis of Prevalence and Risk Factors of chronic obstructive pulmonary disease among Non-smokers (비흡연자 만성폐쇄성폐질환의 유병률과 위험인자의 융합적 분석)

  • Song, Hye-young;Bang, Yun Yi
    • Journal of the Korea Convergence Society
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    • v.9 no.1
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    • pp.85-93
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    • 2018
  • The purpose of the study was to investigate the prevalence and risk factors of chronic obstructive pulmonary disease(COPD) among nonsmokers from the 6th Korea National Health and Nutrition Examination Survey(2013-2015). We used complex sample cross analysis and logistic regression analysis on 4, 911 non-smokers among the patients with chronic obstructive pulmonary disease over 40 years of age. In general characteristics, the prevalence of COPD is higher in the old(p<.001), men(p<.001), rural(p=.044), without spouses(p<.001), less educated(p<.001), agriculture(p<.001). Also, the non-smoker's COPD risk factor is age(p<.001), gender(p<.001), education(p=.022), occupation(p=.022), pulmonary tuberculosis(p<.001), asthma(p<.001). It is necessary to develop a respiratory rehabilitation and intervention program that can be applied in clinical practice based on nursing assessment considering the COPD prevalence and risk factors.

An experimental study on the fire hazard of Sheath Heater (시즈히터의 화재위험성에 관한 실험 연구)

  • Kim, Hakjoong
    • Journal of the Society of Disaster Information
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    • v.10 no.4
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    • pp.511-517
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    • 2014
  • Recently, the fire by sheath heater has been occurred frequently on winter season. The sheath heater has simple internal structure and boils water simply. Therefore, the use of sheath heater has been increased. In this study, found the fire hazard property of sheath heater from understanding the fire mechanism through the experiment to get the measure for decreasing the occurrence of fire. For the analysis of the fire hazard property of the sheath heater, performed the test of temperature change and ignition temperature by using current product. On the result of test, the sheath heaters are the most dangerous appliance to arise fire. Water temperature controller attached to sheath heater is not sufficient to prevent overheating it. The sheath heater should have level switch of water and temperature controller for heater itself to shut off the power supply. Because the cause of fire by sheath heater is overheating itself in the situation of lack water.

Study on HFC-134a Hydrate Formation Rate : according to stirring speed and driving force (HFC-134a 하이드레이트의 형성속도에 관한 연구 : stirring speed, driving force 조건에 따라)

  • Shin, Hyung-Joon;Moon, Dong-Hyun;Seok, Ming-Wang;Lee, Gang-Woo
    • 한국신재생에너지학회:학술대회논문집
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    • 2009.11a
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    • pp.554-554
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    • 2009
  • 지구온난화는 범지구적 환경문제로 매우 빠른 속도로 진행되면서 그 심각성을 더해가고 있다. 특히 해수면 상승이나 대형 태풍, 홍수, 가뭄 등의 이상기후가 빈번하게 발생되며 생태계에도 심각한 타격을 주고 있다. 이러한 지구온난화를 유발하는 물질들에 대해 도쿄의정서(Annex A)에 6대 온실가스($CO_2$ (이산화탄소), 메탄($CH_4$), $N_2O$(아산화질소), PFC(불화탄소), HFC(수소화불화탄소), $SF_6$(육불화황))로 정의 하여 규제대상으로 분류하고 있다. $CO_2$를 제외한 Non-$CO_2$ 온실가스들은 배출량이 $CO_2$에 비해 매우 낮지만 GWP(지구온난화지수)가 매우 커 지구온난화에 미치는 영향이 상당하다. 최근 이산화탄소 이외에 지구온난화 문제를 일으키는 온실가스에 대한 많은 관심으로 대상가스의 처리 또는 재활용을 위한 신기술 및 신공정 개발에 박차를 가하고 있다. 온실가스 중 HFCs는 GWP가 1300으로 미량의 배출로도 심각한 기후변화를 일으킬 수 있는 물질로, 우리나라의 경우 1990년 이후 HFCs 배출량 증가율은 연 평균 4.9% ~ 13.8%이다. 국내외 온실가스 처리기술은 대부분 CO2에 대한 연구개발 및 실증화가 지배적이고, non-CO2에 대한 처리기술 개발수준은 미흡할 뿐만 아니라 본 연구 대상인 HFCs 의 경우에는 처리기술 연구개발이 전무하다. 특히 HFCs는 냉매 또는 발포제로 사용되는데 일반적으로 사용 후 특별한 처리과정 없이 대기중으로 배출된다. 본 연구에서는 non-CO2 가스인 HFC-134a 를 대상으로 혼합가스에서 분리 회수를 위해 하이드레이트 기술을 접목시켜 경제적, 친환경적인 기술개발을 목적으로 한다. kinetic 반응장치와 고압반응기 및 magnetic drive system 을 이용하여 stirring speed와 driving force에 따른 HFC-134a 하이드레이트 형성속도의 상관관계를 제시하고자 한다.

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