• Title/Summary/Keyword: 한국 고지도

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Effect of Angelicae gigantis Radix Extract on Experimentally Induced Hyperlipemia in Rats (한국당귀(Angelicae gigantis Radix) 엑스가 흰쥐의 실험적 고지혈증에 미치는 영향)

  • Lim, Jong-Hoon;Oh, Hyung-Soo;Chung, Myung-Hyun
    • Korean Journal of Pharmacognosy
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    • v.29 no.4
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    • pp.300-311
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    • 1998
  • This study was attempted to investigate the effects of "Angelicae gigantis Radix extract" (AG.EX.) on the activities of GOT and GPT, the contents of total lipid, triglyceride, total cholesterol, phospholipid and ${\beta}-lipoprotein$ in serum, and the weight change ratio of body, liver and spleen in the experimentally induced hyperlipemic rats by administering the extract of 300 and 500 mg/kg p.o.. Significant test was performed by comparision with the biochemical values between control group and experimentally hyperlipemic rats. In the activities of s-GOT and s-GPT inhibition effects were significantly appeared in all dose of AG.EX. (especially more excellent in ethanol extract) and Angelicae acutilobae Radix extract (AA.EX.) as compared with the control group. The content of total lipid was remarkably decreased in all sample group when compared with the control group, and AA.EX. showed more excellent decreasing effect than AG.EX. The contents of triglyceride and total cholesterol were significantly lowered in all sample group, and more significantly decreased in water extract of AG.EX. and ethanol extract of AA.EX. The content of phospholipid was significantly decreased in all sample group and AG.EX. was more significantly decreased than AA.EX. The increasing rate of body weight in all sample groups except AA.EX. 500 mg/kg was increased more than control group and more significantly remarkable in dose of 300 mg/kg than 500 mg/kg. The increasing rate of liver weight in all sample groups was increased more than control group, and AG.EX. was more increased than AA.EX.

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Simultaneous Analysis of Both Lactone Form and Acid Form Monacolin K in Red Yeast Rice by RP-HPLC (역상 HPLC에 의한 홍국 중의 락톤 및 산성 모나콜린 K의 동시분석법)

  • Moon, Young-ja;Wang, Qi-jun;Xu, Bao-jun;Li, Chang-tian;Kim, Jae-hoon;Mo, En-kyeng;Baek, Seoung-young;Il Kwon;Sung, Chang-keun
    • The Korean Journal of Food And Nutrition
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    • v.14 no.6
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    • pp.521-526
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    • 2001
  • A method for the simultaneous and precise determination of lactone form and acid form monacolin K in red yeast rice by HPLC was developed in this study. The standard of acid form monacolin K was prepared by alkaline hydrolysis of its lactone form, which was purchased from Sigma company. The optimum HPLC system for the separation and quantification of acid form and lactone form monacolin K is based on the reversed-phase column, and the acidified mobile phase consisting of acetonitrile : 0.1% trifluoroacetic acid (TFA) water soln : 62 :38, the low limit detection amount was 5 ng (i.e.10 $\mu$l injection of 0.5 $\mu\textrm{g}$/ml) . And the optimal extracting system for monacolins in red rice was also presented here.

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A Study of Convergence Factors involved in Malignant Tumors in the Breast (유방 악성종양에 관여하는 인자 융합 연구)

  • Kim, Jean-Soo
    • Journal of the Korea Convergence Society
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    • v.11 no.10
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    • pp.133-138
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    • 2020
  • The purpose of this study was to identify malignant tumor-related factors in breast diseases and to find out how recently reported oral contraceptives affect women in Korea. The research method is data from the 7th National Health and Nutrition Survey conducted by the Korea Centers for Disease Control and Prevention, and was provided according to the procedures for use guided through the website of the Korea Centers for Disease Control and Prevention. The analyzed data covered a total of 9,981 people, 3,341 in 2016, 3,263 in 2017 and 3,377 in 2018. The results from the study showed the significance of age, smoking, drinking, hyperlipidemia and unmarried related variables, especially the significance of oral contraceptives. Based on this study, it can contribute to active prevention of related factors and cancer-causing suppression policies, especially since the use of oral contraceptives is on the rise, it is believed that continuous research of the subjects to be taken, such as the period and dosage, should be carried out.

Electromagnetic Transmission through Slits in Two Adjacent Conducting Parallel-Plates (근접하는 도체 평행 평판의 슬릿을 통한 전자파 투과)

  • Lee, Jong-Ig;Ko, Ji-Hwan;Cho, Young-Ki
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.20 no.1
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    • pp.83-90
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    • 2009
  • In this paper, the problem of electromagnetic transmission through slits in two parallel conducting plates which separate two half spaces is considered. The coupled integral equations for the electric field distributions over the slits are developed for the case that the TM polarized plane wave is incident on the slit and solved by the method of moments. The transmitted power beyond the slit-perforated conducting parallel plates is computed in order to check the variations of the coupled power through slits against some parameters such as the incident angle of the TM polarized wave, slit width, lateral distance between two slits, and distance between the conducting plates. When the lateral distance between two slits approaches near the multiples of half wavelengths, the transmission resonance (maximum power transmission) is observed. If the slit width in the incident side is narrow and the distance between conducting plates is small compared to the wavelength, the maximum of transmitted power is observed to be nearly independent of the incident angle and slit width. In addition, the mechanism of the transmission resonance in the present geometry is explained using a simplified geometry and its equivalent circuit.

Effects of ice creams supplemented with soy isoflavones on diabetic biomarkers in type II model mice (콩 이소플라본 첨가 아이스크림이 제2형 당뇨모델 마우스의 당뇨 지표에 미치는 영향)

  • Yang, Sun Hee;Choi, Young Sun
    • Korean Journal of Human Ecology
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    • v.23 no.1
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    • pp.137-148
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    • 2014
  • The aim of this study was to determine whether the addition of soy isoflavones to dairy ice cream modifies diabetic biomarkers in the type 2 diabetic model mice. Forty male C57BL/6J-ob/ob mice were randomly divided into 4 groups and fed control diet (basal, 7% fat), MS diet (milk ice cream with sugar, 20% fat), MS-SI diet (MS ice cream with 0.01% soy isoflavones, 20% fat), or MF-SI diet (milk ice cream with 0.01% soy isoflavones, 5% fructooligosaccharide, 20% fat) for 12 weeks. Blood response area by glucose tolerance test, plasma levels of glucose, insulin, C-peptide, leptin, and blood $HbA_{1c}$ were not significantly different among all the groups. Concentrations of interleukin-6 and tumor necrosis factor-${\alpha}$ secreted from splenocytes induced by Concanavalin A were not significantly different among all the groups. In conclusion, soy isoflavones supplemented to ice cream did not alter diabetic biomarkers in diabetic type 2 model mice.

Design of V/UHF band Small Dipole Circular Array Active Antenna (V/UHF대역 소형다이폴 원형배열 능동안테나 설계)

  • Ko, Ji-Hwan;Lee, Cheol-Soo;Kim, Kang-Uk;Cho, Young-Ki
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.1
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    • pp.6-16
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    • 2009
  • For the application to the direction finding(DF) antenna for V/UHF bands, circular active array composed of 9 dipole element has been investigate. For miniaturization of the overall size array, the element has been chosen to be of the top-hat dipole type. For the broadband operation over 20-1300MHz, some number of pin diodes have been inserted in each arms of each dipole element. By employing this type of each element dipole, the effective dipole length can be increased or decreased according as the inserted pin diodes is on or off. The active array antenna has been design to be directly connected to the balanced push full amplifier such that the amplifier may play a role as a balloon and may improve the sensitivity as a receiver as well. The active array antenna has been designed and fabricated. Some experimental results have been presented in comparison with simulated results.

The inhibitory effects of Soongijeseub-bang(順氣除濕方) on the obese-mice caused by high-fat diet (순기제습방(順氣除濕方)이 고지방식이(高脂肪食餌)로 유발된 비만(肥滿) 백서(白鼠)에 미치는 영향)

  • Lee, Woo-Yeol;Shin, Hyun-Kyoo
    • Korean Journal of Oriental Medicine
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    • v.14 no.1
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    • pp.161-171
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    • 2008
  • Objective : In order to investigate the effects of Soongijeseub-bang(here in after referred to SJB) on the obese gene and obese inhibitory, C57BL/6 mice were induced by high fat diet Methods : C57BL/6 mice were divided into three groups(normal, high fat diet with control, high fat diet with SJB extract) and fed for 15 weeks. And measured body weight change, the weight change of the adipocytes in body, the levels of ALT, AST, creatinine, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, NEFA(non-esterified fat acid), glucose in serum and the expression of ${\beta}3AR$, leptin, and TNF- ${\alpha}$ gene in primary adipocytes and adipocytes tissue. Results : The following results were obtained in this study. 1. SJB 500 mg/kg extract group showed significant decrease in final weight. 2. SJB 500 mg/kg extract group showed significant decrease in the amount of adipocyte in weight. 3. All experimental group showed significant decrease in ALT and AST levels. 4. All experimetal group did not show significant decrease in glucose and creatinine levels. 5. All experimental group showed significant decrease in total cholesterol, LDL-cholesterol, triglyceride and NEFA levels. HDL-cholesterol were increase significantly in SJB 500 mg/kg extract group. 6. SJB 500 mg/kg extract group showed significant decrease in leptin levels. 7. All experimental group showed significantly increased expressions of fJ 3AR in primary adipose cell and 3T3-Ll cell, and those of leptin in primary adipose cell and 3T3-Ll cell were decreased significantly. SJB $100{\mu}l/ml$ extract group showed significant decrease in the expression of TNF-${\alpha}$. 8. SJB 500 mg/kg extract group showed decrease in the size of adipocyte in adipocytes tissue. 9. All experimental group showed significant decrease in adipose vacuoles in liver tissue.

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Effects of Soybean Germ on the Lipid Composition of Serum in Cholesterol Fed Rats (고콜레스테롤 식이로 사육한 흰쥐 혈청 지질의 성분에 미치는 대두 배아의 영향)

  • 이홍수;김현대;류병호
    • The Korean Journal of Food And Nutrition
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    • v.13 no.4
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    • pp.312-318
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    • 2000
  • This study was conducted to investigate the effects of soybean germ of Glycin max Merrill on the improvement of lipids in the serum of cholesterol supplemented diet induced dietary hyperlipidemic rats fed for 4 weeks. The experiment diet was mixed with 0.75% cholesterol recieved a basic diet mixed with 0.75% cholesterol. No significance differences in efficency of food, liver kidney and heart. Concentration of total cholesterol and LDL cholesterol in serum was significantly lower in the methanol extracts of soybean sprout than the cholesterol supplemented diet group. In the ratio of HDL-cholesterol concentration to total cholesterol concentration, the methanol extracts of soybean sprout administration group was higher percentage than the ocher groups. Atherosclerotic index was lower in the methanol extracts of soybean sprout group than in the cholesterol group. Concentration of phospholipid in serum was more decreased in the methanol extracts of soybean sprout group than in the cholesterol diet group. From these results, the methanol extracts of soybean sprout were effective on the improvement of the lipid compositions in the serum of high fat diet induced dietary hyperlipidemic rats.

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Evaluation of adsorption of flexography ink particle on cationic patched filler (양이온 패치된 필러를 이용한 플렉소 잉크 입자의 흡착특성 평가)

  • O, Gyu-Deok;Lee, Hak-Rae;Yun, Hye-Jeong;Kim, Jin-U
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2010.04a
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    • pp.207-207
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    • 2010
  • 고지로부터 유입된 플렉소 잉크는 수성잉크의 고유 특성으로 인해 세척 공정을 통해서만 제거된다. 이는 다량의 용수 사용을 유도함으로서 에너지 소비 및 환경오염 요소를 증대시키는 주요 원인으로 작용하고 있다. 최근에는 이들을 효과적으로 제거하기 위한 많은 연구가 수행되고 있다. 특히 기존의 이물질 제거 방법 중에서 부유부상법을 이용한 제어 방안이 주목 받고 있으며 이는 잉크 제조 시 건조 잉크 입자의 소수성을 부여하는 방법 또는 탈묵 pH 조건에서 잉크 자체의 soluble한 요소를 최소화함으로서 잉크입자의 미분화를 최소화 하는 방안, 그리고 이와 더불어 부유부상 공정에서 효과적인 기포 부착을 유도하는 방안 강구 등 효과적인 제거를 위한 연구가 다각도로 수행 되고 있다. 이러한 연구 과정 중에 직면하고 있는 가장 큰 문제점은 플렉소 잉크가 쉽게 미분화 된다는 것이다. 특히 나노 크기로 미분화된 잉크는 세척 이외에는 제거 방법이 거의 없고 폐쇄화된 초지 공정에서 지속적인 농축을 유발하여 심각한 계 내 오염을 야기할 뿐만 아니라 기존의 수질제어 시스템에서도 효과적으로 제거되기 어렵기 때문에 수질오염을 유발하는 주요 물질로 작용하고 있다. 또 일부 잉크 입자들은 중금속을 함유하고 있어 제품에 포함될 경우 잠재적 유독물질로 작용할 수 있으며, 만일 이들을 포함한 공정수가 방류될 경우 심각한 수질오염을 유발할 수 있다. 이에 대한 심각성이 최근 중요하게 대두됨에 따라 본 연구에서는 미분화된 플렉소 잉크 입자의 제어를 위한 기초 연구로서 미분화된 잉크를 비중이 높고 상대적으로 큰 입자를 가지는 filler에 흡착시켜 제어하는 방안을 모색하였고 이는 추후 Filler에 흡착된 잉크 입자를 이용하여 침전을 통한 제거 또는 부유부상이 가능한 입자 크기로 형성시켜 제거하는 방안을 제시하기 위한 기초 연구로서 수행되었다.

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Research on the Use of Rainwater During Fire Suppression (화재진압시 빗물이용에 관한 연구)

  • Gu, Dong-Uk;Shin, Ho-Joon;Back, Min-Ho
    • 한국방재학회:학술대회논문집
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    • 2011.02a
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    • pp.191-191
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    • 2011
  • 최근 빗물이 우리가 앞으로 이용할 수 있는 수자원이라는 사회적인 인식의 변화와 함께 빗물이용이 더욱 요구되어졌다. 특히 빗물의 이용 저류 침투를 목적으로 하는 우수 관리에 대한 관심이 증가하면서 빗물이용시설의 설치, 운용의 필요성이 대두되고 있다. 이에 반해 화재발생은 해마다 증가하고 있으며, 화재 증가는 소방력 활동의 증가로 귀결되는데 현장활동 인력과 장비 그리고 화재를 진압하는데 사용되는 소방용수 증가를 의미한다. 따라서 본 연구는 빗물을 소방용수로 즉, 화재진압시 활용 가능성과 수자원 절약, 화재 사각지역 해소 측면을 살펴보기 위해서 통계분석, 현장조사, 기존 빗물이용시설 및 향후 완공 예정인 우수유출저감시설 활용과 소방용수 미설치 지역과 소방관서 옥상에 빗물이용시설 설치 방안을 제시하였으며, 그에 따른 공공서비스 확대와 경제성 분석을 통하여 다음과 같은 연구결과를 도출하였다. 첫째, 기존 빗물이용시설을 소방용수로 적극적으로 활용해야 한다. 빗물이용시설의 주 용도로 조경용수, 청소용수, 소방용수로 나눌 수 있는데 이수 측면에서 화재가 발생하지 않으면 소방용수로서 이용이 거의 없는 실정이다. 이는 해당 건물관계자나 소방대원들이 빗물이용시설을 인식을 못하고, 사용과 접근성 불편으로 상수도와 연결된 소화전에 의존하는 경우가 많다고 본다. 둘째, 상수도시설이 없는 지역은 빗물이용으로 소방용수를 확보해야 한다. 섬, 산간, 고지대, 농촌지역 등 상수도 서비스를 공급받지 못하는 지역은 화재발생시 수원확보곤란으로 인명과 재산피해의 증가요인으로 작용할 수 있다. 공공서비스 확대차원에서 화재 사각지역을 해소하기 위해 지붕면을 이용한 각 가정마다 또는 공동 빗물저장소와 지형의 비탈면을 이용한 빗물이용시설 설치로 소방용수 확보의 필요성을 확인했다. 셋째, 소방관서 신설시 빗물이용시설을 도입하여 설치한다. 화재통계와 현장조사를 통하여 소방차 출동대기부터 화재진압까지 많은 양의 물이 사용되는 것으로 파악되었다. 대부분 먹는 물 즉, 상수도를 이용한다는 점에서 수자원 절약과 화재진압에 사용된 물은 재생 불가능이라는 환경보전 측면에서 빗물이용으로 해답을 찾아본다. 따라서 빗물을 많이 저장할 수 있도록 옥상, 부지 등 집수면적을 확대하고 이에 적합한 저류시설을 갖춘 빗물이용시설을 설치한다. 끝으로 신속하고 효율적인 화재진압이 중요한 만큼 빗물을 소방용수로 활용하고자 할 때는 언제 어디에서나 현장 접근성, 사용 편리성, 충분한 수량을 고려해야한다.

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