• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.4
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• pp.533-540
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• 2022

Specialists diagnose skin cancer using a dermatoscopy to detect skin cancer as early as possible, but it is difficult to determine accurate skin lesions because skin lesions have various shapes. Recently, the skin lesion segmentation method using deep learning, which has shown high performance, has a problem in segmenting skin lesions because the boundary between healthy skin and skin lesions is not clear. To solve these issues, the proposed method constructs a transformer block to effectively segment the skin lesion, and constructs an edge decoder for each layer of the network to segment the skin lesion in detail. Experiment results have shown that the proposed method achieves a performance improvement of 0.041 ~ 0.071 for Dic Coefficient and 0.062 ~ 0.112 for Jaccard Index, compared with the previous method.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.1
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• pp.78-95
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• 2023

목적 : 마이크로니들 패치는 피부장벽의 주요 구성성분인 각질층을 관통할 수 있어 일반적인 경피를 통한 약물 전달 수단보다 더 효율적으로 약물을 전달할 수 있다는 장점이 있어 다양한 분야에서 응용되고 있다. 본 임상연구는 아토피피부염 환자의 피부 건조 증상에 대하여 용해성 히알루론산 마이크로니들 패치와 외용제를 병행하여 용해성 마이크로니들 패치의 유효성과 안전성을 평가하였다. 방법 : 본 연구는 단일 기관, 연구자 주도, 평가자 눈가림, 인체 분할 연구로 설계된 무작위 배정 임상시험으로, 피부건조 증상이 있는 아토피피부염 환자 20명을 대상으로 임상연구를 수행하였다. 한 명의 피험자에서 2곳의 시험 병변을 선택한 후, 무작위 배정으로 각각 시험 병변과 대조 병변을 결정하여 2주 동안 매일 양측 병변에 모두 아로마 크림을 도포한 다음, 시험 병변에만 용해성 히알루론산 마이크로니들 패치를 추가로 부착하였다. 결과 : 1차 유효성 평가지표인 local scoring atopic dermatitis(L-SCORAD) index는 치료 후에 시험 병변이 대조 병변보다 유의성 있게 호전되었다. 2차 유효성 평가지표 중 피부 건조감 VAS와 피부 수분 함유량도 시험 병변이 대조 병변보다 유의성 있는 개선을 보였다. Investigator's Global Assessment scale, 소양감 VAS, 경피수분손실량에 있어서는 시험 병변과 대조 병변 모두 치료 후에 유의성 있게 호전되었으나, 두 병변 간의 차이에는 유의성이 없었다. 이상 반응은 나타나지 않았으므로 안전성도 확인되었다. 결론 : 용해성 히알루론산 마이크로니들 패치와 외용제 병행치료는 외용제만 사용하였을 때보다 L-SCORAD index 및 피부 건조감 VAS, 피부 수분 함유량에 있어서 아토피피부염의 증상을 유의성 있게 개선시켰다.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.5
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• pp.369-374
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• 2008

Purpose: F-18 FDG PET/CT has excellent sensitivity and specificity for staging non-Hodgkin lymphomas, but to the author's knowledge few studies to date have evaluated FDG PET/CT in peripheral T cell lymphoma. We evaluated the usefulness of F-18 FDG PET/CT in staging of patients with peripheral T cell lymphoma, especially indolent cutaneous T cell lymphomas. Materials and Methods: Twenty five patients (M:F=17:8, age $53.7{\pm}14.8$ yrs) with biopsy-proven indolent cutaneous T cell (CL) or noncutaneous T cell lymphomas (NCL) underwent PET/CT scans for staging at baseline. Peak standardized uptake values (p-SUV) of all abnormal foci were measured and compared between cutaneous and noncutaneous lesions. F-18 FDG PET/CT was performed on 6 patients with indolent CL and on 19 patients with NCL. Results: All 6 patients with indolent CL had no significant FDG avidity in the skin despite histologically positive cutaneous lesions. However, FDG avidity appeared in extracutaneous lesions (lymph nodes) in two patients with CL where CT imaging suggested lymphoma involvement (mean p-SUV $4.26{\pm}0.37$ in noncutaneous lesions in CL). In NCL, FDG avidity was demonstrated in all lesions where CT imaging suggested lymphoma involvement (mean p-SUV, $8.52{\pm}5.00$ in noncutaneous lesions in NCL). Conclusion: F-18 FDG PET/CT has the limitation of usefulness for the evaluation of the skin in indolent CL. In contrast, F-18 FDG PET/CT is sensitive in staging evaluation of extracutaneous lesions regardless of CL or NCL.

• Smart Media Journal
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• v.13 no.3
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• pp.53-61
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• 2024

This paper presents a novel M-shaped encoder-decoder architecture for skin lesion segmentation, achieving better performance than existing approaches. The proposed architecture utilizes the left and right legs to enable multi-scale feature extraction and is further enhanced by integrating an attention module within the skip connection. The image is partitioned into four distinct patches, facilitating enhanced processing within the encoder-decoder framework. A pivotal aspect of the proposed method is to focus more on critical image features through an attention mechanism, leading to refined segmentation. Experimental results highlight the effectiveness of the proposed approach, demonstrating superior accuracy, precision, and Jaccard Index compared to existing methods

• Journal of the Korea Computer Industry Society
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• v.7 no.5
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• pp.563-572
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• 2006

Advantage that light transmission treatment way of most suitable through skin can investigate light directly in part ar there is difference in ability photoelectricity month by diverse complexion of horn character department which is branch or head of a family outside part of skin and treatment according to various patient can be inappropriate. By result that this research uses color information after search each color ingredient that ingredient of HIS and YIQ that use method, color information to use skin impedance way and color information through skin area ion and difference video to do fixed measuring by light investigation way by skin impedance corresponds to skin color in an experiment though is most universal result according to patient's skin model area detection each single person's skin model through videotex automatically create and because measuring, investigate skin color, energy, wave length, approximately, transmission time, model of most suitable that draw pulse delay and so on and want and special quality, and saved standard of disease treatment pulse modeling by skin impedance, and design and manufacture light investigation pulse modeling system of most suitable by skin subordinate, and constructed suitable treatment pulse database by skin color.

• Journal of the Institute of Convergence Signal Processing
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• v.23 no.4
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• pp.256-263
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• 2022

Skin cancer is one of the most common diseases in the world, and the incidence rate in Korea has increased by about 100% over the past five years. In the United States, more than 5 million people are diagnosed with skin cancer every year. Skin cancer mainly occurs when skin tissue is damaged for a long time due to exposure to ultraviolet rays. Melanoma, a malignant tumor of skin cancer, is similar in appearance to Atypical melanocytic nevus occurring on the skin, making it difficult for the general public to be aware of it unless secondary signs occur. In this paper, we propose a skin cancer lesion edge detection algorithm and a deep learning model, CRNN, which performs skin cancer lesion classification for early detection and classification of these skin cancers. As a result of the experiment, when using the contour detection algorithm proposed in this paper, the classification accuracy was the highest at 97%. For the Canny algorithm, 78% was shown, 55% for Sobel, and 46% for Laplacian.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.4
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• pp.337-342
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• 2016

Melasma has several well-recognized etiologic factors, but most researches focus on melanogenesis. The purpose of this study is to show improvement of melasma by reducing vascularity distinguished from melanogenesis. We examined 20 Korean women with both melasma and solar lentigo that were visually assessed by a dermatologist. The volunteers applied functional cosmetics for 8 weeks. We analyzed the results obtained using the chromameter, evaluating the skin color of three areas (melasma lesions, solar lentigo lesions, and non-lesional skin) on the face of volunteer. There was a statistically significant improvement in the brightness and redness of melasma lesions compared to those of non-lesional skin after 8 weeks. Also, we observed that the improvements in the brightness of melasma lesions and solar lentigo lesions were similar. However, the redness of melasma lesions improved more than that of solar lentigo lesions with statistical significance after 8 weeks. In this study, we have shown that brightness and redness in melasma lesions can be improved by functional cosmetics. Thus, we suggest redness to be an additional suitable parameter for the evaluation of melasma lesions.

• Journal of the korean veterinary medical association
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• v.51 no.8
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• pp.443-445
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• 2015

• Clinical and Experimental Pediatrics
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• v.52 no.2
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• pp.247-250
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• 2009

Stevens-Johnson syndrome (SJS) presents with widespread blisters, erythematous or purpuric macules, and one or more mucous membrane erosions. Various etiologic factors, including infection, vaccination, drug administration, systemic diseases, physical agents, and food have been implicated as causes of SJS. Mycoplasma pneumoniae is the most common infectious agent to cause SJS in children. In recent literature, M. pneumoniae-induced SJS with mucositis that lacks the typical target lesions has been described. We report a case of a 6-year-old boy with swelling, peeling of the lips, and red eyes with photosensitivity. On physical examination, he showed severe oral mucositis and conjunctivitis with no evidence of skin lesions. Mycoplasma antibody, which was positive with titers of more than 1:2,560. For patients presenting with fever and mucositis of unknown origin, M. pneumoniae should be considered.

• Journal of Veterinary Clinics
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• v.13 no.1
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• pp.77-80
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• 1996

인도의 아메다바드 동물원에서 사육중인 1년생의 수컷 우는 사슴(Muntiacus muntjak)에서 피부사상균증이 발생했다. 발병된 사슴의 얼굴, 머리 및 목 부위 피부에는 모양이 불규칙하고 각피성인 여러개의 회백생 병변을 나타내었다. potassium hydroxide기법에 의해 피부병변에서 Trichophyton verrucosum이 검출되었다. 감염된 피부와 털 시료를 곰팡이 배지에 배양하여 같은 병원체가 검출되었다. 이 사슴과 밀접하게 접촉하였던 사육사에게서는 감염증이 확인되지 않았다. 동물원 동물의 피부염을 감별하는데 있어서 피부사상균을 고려해야 한다는 점이 강조되었다. 저자들의 소견으로는 이것이 인도산 우는 사슴에서 발생한 Trichophyton verrucosum 감염증으로써 최초의 확진된 보고이다.