• Proceedings of the Korea Information Processing Society Conference
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• 2014.04a
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• pp.840-843
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• 2014

사실적 피부 렌더링은 피부 표면에서 일어나는 확산반사(Diffusion) 및 경면반사(Specular) 뿐 만 아니라 피부층 내에서 산란되어 나오는 산란광과 얇은 피부층을 통과하는 투과광 등을 고려하여 렌더링 되어야 한다. 이를 물리적인 개념들을 사용하여 실시간으로 계산하여 표현하는 것은 많은 계산량과 시간을 필요로 하므로 확산 반사 및 경면 반사 등을 미리 계산하여 텍스쳐로 저장하고 재사용하는 사전정의 BRDF 방법으로 근사화하여 표현할 수 있다. 하지만 사전정의 BRDF를 통해 생성된 피부 투과광색상 텍스쳐 맵은 그 색상이 고정되어있어 조명의 색상이 바뀌어도 피부를 투과하는 빛의 색상이 변하지 않아 부자연스러움을 보인다. 본 논문에서는 이러한 문제를 해결하기 위해 물체와 조명간의 거리를 이용하여 빛의 감쇠비율을 구하고 조명의 색상 값과 감쇠비율을 이용하여 피부 투과광 색상 텍스쳐 맵의 RGB채널 수정을 통해 피부 렌더링에서의 자연스러운 투과광 표현이 가능함을 보였다.

• Journal of Marine Life Science
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• v.8 no.2
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• pp.160-165
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• 2023

This study describes the light microscopical cell types and histochemical characteristics as a preliminary study for the research on integument of the walleye pollock Gadus chalcogrammus in accordance with the physiological and environmental changes. The lateral line of the integument surface showed a curve in the anterior part and was straight from the middle to the posterior part. Integument is composed of outer epidermis and inner dermis. The epidermis is a stratified layer composed of epithelial cells, mucous cells, and club cells. Epithelial cells are classified into squamous superficial cell, cuboidal intermediated cell and columnar basal cell. The thickness of epidermis was 122.9 ㎛, and the ratio of epidermis thickness to body length was 0.03%. The mucous cell and club cell of unicellular gland were mainly distributed in the apical and middle layer of epidermis. The mucous cell contained mucosal materials of acidic glycoprotein. The proportion of mucous cells and club cells were 21.3 (± 7.0)% and 4.0 (± 1.0)% of epidermal area, respectively. The dermis was dense connective tissue layer and composed of mainly collagen fibers. It also contained fibrocytes, blood vessels, melanophores and scales.

• 건강소식
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• v.20 no.9 s.214
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• pp.12-13
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• 1996

각종 공해로 인한 오존층의 파괴와 더불어 피부에 생기는 암에 대한 관심이 높아지고 있다. 피부암은 크게 양성종양과 악성종양으로 나눌수 있는데, 본 글에서는 대표적인 피부악성종양인 기저세포암, 편평세포암, 그리고 악성흑색종에 관하여, 각각의 원인(특히 태양광선과의 관계), 증상. 치료방법 및 예방법 등을 알아보고자 한다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.40 no.1
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• pp.1-10
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• 2014

At present, there are few research papers on skin penetration of cosmeceutical ingredients. What is worse is that in vivo studies are hard to find. In this study, we measured skin epidermal penetration of cosmeceutical ingredients using in vivo Raman spectroscopy and compared with the results obtained from experiments using in vitro franz cell. Results showed that ascorbyl-2-glucoside, retinol, retinyl palmitate, and kojic acid were good for penetration ratio in measurement in vitro and retinol, vitamin C, and arbutin were good in measurement in vivo. Among them, retinol was best in skin penetration in vivo experiment using Raman spectroscopy and ascorbyl-2-glucoside was best in skin penetration in vitro experiment using Franz cell system. It is estimated that the differences were originated from the experimental procedures of two different methods; in vivo Raman experiment can be sensitive to the effect of epidermis and dermis as characteristics of matter by estimating the stratum corneum and in vitro measurement is evaluation of material to penetrate skin of hairless mouse. However, most penetration barrier is the stratum corneum, thus it is important to examine movement of material in the stratum corneum. We expect that these results provided useful information for many cosmetic related research.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2000.05a
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• pp.387-388
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• 2000

어류는 엷은 피부를 경계로 하여 체액과 삼투압의 차가 있는 수중에서 생활하고 있다. 다른 척추동물과 달리 표피의 살아있는 세포가 직접 외부 환경과 접촉하고 있으며(Hawkes, 1974), 그로 인해 겪게 되는 삼투압의 불균형과 환경적인 유해성분 등에 직면하게 되기 때문에 여러 가지 형태의 특이한 구조를 갖고 있다. 어류 피부계의 미세구조에 대한 연구로는 Brown and Wetting(1970), Zaccone(1983), Jeong and Moon(1994), Lee and Kim(1999) 등의 보고를 들 수 있다. 본 연구는 저서 정착성 어류인 넙치 피부 상피층의 조직학적 관찰을 통하여 추후 이들 어류의 생활환경 및 생리적 변화와 관련된 피부계의 변화양상에 관한 연구의 기초자료를 제공하고자 하였다. (중략)

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.1
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• pp.81-87
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• 2018

The objective of this article is to provide analytical tools for the scattering of stratum corneum (SC) and to check whether the optical clearing agents (OCAs) could be applied in optics affecting the scattering reduction. Dark field images of tape striped corneocyte separates scattered light of the SC from others in vitro. Several optical clearing agents were tested to reduce the scattering. Physical properties of SC such as water contents, keratin configuration and volume after OCAs treatment were investigated by FT-IR and 3D laser microscope. Several reducing sugars, monomeric sugars, sugar alcohol, and hyaluronic acid, which were used as humectants in cosmetic field, also reduced scattering. However, unlike dehydration in optics, water penetrated into the keratin in SC and scattering was decreased at low concentration of OCAs. In that condition, the volume of corneocyte was increased and stiffness seemed to decrease. The analyzing of tape-stripped SC, showed the change of optical and physical properties of corneocyte by optical clearing agents. The hydration of SC layer by optical clearing agents decreased the scattering of corneocyte and thus improved the skin appearance and moisturizing effect, which are important benefits in the cosmetic field and could provide new possibility to develop skin care study targeting at SC.

• Proceedings of the KSMRM Conference
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• 1997.10a
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• pp.42-42
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• 1997

• Korean Journal of Food Science and Technology
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• v.40 no.4
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• pp.436-442
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• 2008

Hydroxyproline and Pro-Hyp dipeptide are the digestive products of collagen hydrolysate called collagen peptide. Some suggested that collagen peptides could improve aged or damaged skins, however, the effects of collagen peptides on the skin have not been known. In this study, we investigated the effects of digestive products of collagen peptides, hydroxyproline and Pro-Hyp dipeptide on skin quality using the UV-damaged dorsal skin of hairless mouse as a model system. Female SKH hairless mice were pre-irradiated with UV for 7 weeks, and then hydroxyproline, Pro-Hyp dipeptide were orally administered for 7 weeks with UV irradiation. Wrinkle formation (by replica image), skin elasticity, barrier status (by TEWL, transepidermal water loss), epidermis thickness, and biophysical changes in the stratum comeum (by hematoxylin & eosin staining) were examined. With the oral peptide treatment, effects such as skin barrier maintenance, anti-skin thickening, and recovery of the stratum corneum were observed. These results indicate that oral intake of collagen peptides may have beneficial effects on damaged skin cells.

• Applied Microscopy
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• v.40 no.4
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• pp.245-251
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• 2010

In this study, we applied 15% glycolic acid peeling agent and 30% glycolic acid peeling agent to the dorsal skin of mice and analyzed the oil content, moisture content, and pH value of the skin before and after test using cutometer. Ultrastructure for changes in the epidermis of mice were observed under a dermoscope and a scanning electron microscope before and after test. When using 15% glycolic acid peeling agent, the changes of moisture content was measured 74.67 AU for the normal control group and 70.21 AU for the experimental group, the oil content was 13.49 mg/$cm^2$ for the normal control group before test and 8.25 mg/$cm^2$ after test, and the pH value was 6.70 and 5.36 before and after test, respectively. When using 30% glycolic acid peeling agent, the moisture content was measured 74.46 AU for the normal control group before test and 53.50 AU for the experimental group after test, the oil content was 13.82mg/$cm^2$ and 5.70 mg/$cm^2$ before and after test, and the pH value was 6.45 and 4.58 before and after test, respectively. As such, it was found that the changes of moisture and oil content on the skin rely on the concentration of peeling agent and the degree of exfoliation of keratin. The surface of stratum corneum of mice with application of 15% glycolic acid peeling agent was relatively smooth and the exposed cellular surface of keratinocyte had some wrinkles. The surface of stratum corneum of mice with application of 30% glycolic acid peeling agent was smooth. No wrinkles were observed under high-resolution scanning electron microscope.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.37 no.3
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• pp.283-288
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• 2011

Since minerals are in ionic forms in aqueous phase (like deep sea water), it is very hard to incorporate concentrated minerals in gel like cosmetic formulations which are generally composed of carbomer or acrylates polymer. In this study, we invented a salt-resistant network formulation made of silicon copolyol. It was found that the network formulation traps minerals (especially from marine) in a mesh-like silicone copolyol structure. Since the mineral-containing formulation makes a very thin film on the skin, minerals could be easily absorbed into stratum corneum. In 6 weeks in vivo test, it was found that the novel mineral formulation increased the amounts of amino acids, major components of natural moisturizing factors (NMFs), as well as levels of minerals. It was also found that the moisture contents and the brightness of the skin increased.