• Title/Summary/Keyword: 피부유형

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Development of targeted amplicon next-generation sequencing panel of 50 SNPs related to externally visible characteristics and behavior (외형 및 행동 습관 관련 50개 SNP 마커 분석을 위한 targeted amplicon next-generation sequencing 패널 개발)

  • Hee-Yeon Park;Yoonji Noh;Eung-Soo Kim;Hyun-Chul Park
    • Analytical Science and Technology
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    • v.37 no.3
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    • pp.189-199
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    • 2024
  • In forensic genetics, when it is not possible to confirm an individual's identity through STR profile analysis, additional information about the individual can be obtained using DNA-based phenotypic traits estimation. Recently, various researches have been conducted on methods to determine externally visible characteristics (EVC) such as eyes, hair, and skin color. However, relying solely on such phenotypic traits information has limitations for application in East Asian regions, including Korea. In this study, in order to utilize EVC related to an individual's appearance as investigative information, SNPs related to eye shape, hair thickness, skin color, as well as baldness, body type, high myopia, facial shape, acne, and behavioral habits were explored. A total of 50 SNPs were selected, and a targeted amplicon NGS panel capable of amplifying them all at once was developed. Experimental results confirmed the allelic types and frequencies of the 50 SNPs in 14 samples. We plan to use this panel to investigate the correlation between genotype and phenotype using various samples, and to develop methods for interpreting the results.

Bare-Metal Stent in Dysfunctional Hemodialysis Access: An Assessment of Circuit Patency according to Access Type and Stent Location (혈액투석 접근로 기능부전에서의 비피복형 스텐트: 접근로 종류와 스텐트 위치에 따른 개통률 평가)

  • Kyungmin Lee;Je Hwan Won;Yohan Kwon;Su Hyung Lee;Jun Bae Bang;Jinoo Kim
    • Journal of the Korean Society of Radiology
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    • v.84 no.1
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    • pp.197-211
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    • 2023
  • Purpose To evaluate the circuit patency after nitinol bare-metal stent (BMS) placement according to the type of access and location of the stent in dysfunctional hemodialysis access. Materials and Methods Between January 2017 and December 2019, 159 patients (mean age, 64.1 ± 13.2 years) underwent nitinol BMS placement for dysfunctional access. The location of stents was as follows: 18 brachiocephalic vein, 51 cephalic arch, 40 upper arm vein, 10 juxta-anastomotic vein, 7 arteriovenous (AV) anastomosis, and 33 graft-vein (GV) anastomosis. Circuit patency was evaluated by the Kaplan-Meier method, and cox regression model. Results A total of 159 stents were successfully deployed in 103 AV fistula (AVF) and 56 AV graft (AVG). AVG showed lower primary and secondary patency at 12-months compared with AVF (primary patency; 25.0% vs. 44.7%; p = 0.005, secondary patency; 76.8% vs. 92.2%; p = 0.014). Cox regression model demonstrated poorer primary patency at 12 months after stenting in the cephalic arch and GV anastomosis compared with the other sites. Conclusion AVF showed better primary and secondary circuit patency at 12 months following the placement of BMS compared with AVG. Stents in the cephalic arch and GV anastomosis were associated with poorer primary patency at 12 months compared to those in other locations.

Relationship between Appearance Management Behavior and Information Search of Male Workers (남성의 외모관리 행동과 정보탐색과의 관계 고찰)

  • Kim, Hye-Kyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.11
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    • pp.6484-6491
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    • 2014
  • The human's basic desire for aesthetics, which has existed along with human history, has been more individualized and diversified according to the progress of modern economic social change. In the case of men, who have a relatively higher connection and experience of mass media compared to women, there is a characteristic to apply and utilize information acquisition and share appearance management quickly on the media. This paper classified and arranged the image and characteristics of the modern male image analyzed the relationship between men's appearance management and information exploration. In addition, exploration relation per information medium was considered by dividing the men's appearance management behavior and characteristics into make-up, hair management, skin care, hands and feet care, and plastic surgery. This appears to be useful for the industrial group, e.g. beauty treatment, cosmetics, hospital, etc. as advertisement marketing information.

A Study on the Setting of Breast Measurement Points on 3D Scan Data

  • Sohn, Boo-Hyun;Han, Hyun-Suk
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.5
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    • pp.81-90
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    • 2020
  • In this paper, we propose setting measurement point in the 3D scan data based on the manual measurement data. The optimal 3D body scan postures and measurement points for automatic measurement of breast were set up. The outer breast point may be different depending on the body shape or standing posture as it is on the line connected from the bisecting point of the lateral waist thickness to front armpit point. Therefore, it is necessary to consider the breast-related outer point proposed in this study. And many researches need to reduce the differences between MAM and 3D dimension items associated with the upper breast point. When measuring depth, the difference by pressing in MAM should be taken into account. And the differences in flexion depending on breast type can make a difference in the 3D measurement. So the measurement method in 3D scan should be further studied depending on the types of breast and verified by multiple subjects.

Antimicrobial and Antioxidative Effects of Isoflavonoids on Skin Microbial Inflammation Pathogens (Isoflavonoid의 피부염증균에 대한 항균 및 항산화효과)

  • Shin, Jung-Mi;Yu, Hung-Won;Lee, Hyun-Ok;Lee, Mi-Hee;Baek, Seung-Hwa
    • YAKHAK HOEJI
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    • v.50 no.1
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    • pp.15-20
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    • 2006
  • Puerarin and daidzin have been isolated from Puerariae thunbergiana Benth. Structures were determined by spectroscopic methods. Compounds showed weak antimicrobial activity against S. mutans, S. epidermidis, S. aureus, and C. albicans (MIC, $800{\mu}g/ml$). However, these compounds were not antioxidative. Puerariae thunbergiana Benth. extracts against microorganisms were evaluated in terms of the minimum inhibitory concentrations (MIC). In general, C. albicans was stronger antimicrobial activity than the other microorganisms. The antioxidative activity of was observed in the etyl acetate extract ($IC_{50},\;119.87{\pm}0.16\;{\mu}g/ml$). The DPPH radical scavenging effect ($IC_{50},\;1,673.3{\pm}0.54\;{\mu}M$) of the puerarin was comparable with that of synthetic antioxidant, BHA $(IC_{50},\;88.39{\pm}1.1){\times}10^{3}{\mu}M$. These results suggest that puerarin and daidzin have a potential antimicrobial activity.

"유문사친(儒門事親)"의 '토법(吐法)'에 관한 연구

  • Kim, Gi-Uk;Park, Hyeon-Guk;Kim, Yong-Ju
    • Journal of Korean Medical classics
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    • v.21 no.2
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    • pp.193-200
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    • 2008
  • 재전통의학이론상일반운용'토법'적주요목표이병인화병위양종분류인식하거적(在전統의학理논上一般운用'吐法'的主要目표以病因和病位양종分류인식下去的). 관우병인의미착직접토출격상(관于病因意味着직接吐出膈上), 위완적담음숙식지인착오적섭식지유독지물(胃脘的痰음宿食지因錯오的섭食之有毒之物), 관우병위가이설(관于病位可以설), '기고자(其高者), 인이월지'적'기고자'시지상완(因而越之'的'其高者'是指上脘), 격상적유형실사(膈上的有形실邪). 장자화재 "유문사친"상설"일토지중(장子和在"儒門事親"上설"一吐之中), 변태무궁(변태无궁), 루용루험(屢用屢험), 이지불의(以지不疑)", 몰구완격담식혹비교고적병위(沒拘脘膈痰食或比較高的病位). 이차통과흔다임상경험(而且通과흔多임床경험), '토법(吐法)'능취득료타개현부이발산피부적청양(能取得了打개玄府而발散皮부的淸양), 타개하초(打개下焦), 천착장중적옹체(穿着腸中的壅滯), 통조수도(通조水道), 단절수지상원(단絶水之上源), 접통울체(接通울滯), 피상행진기(被上行진기), 접통관객(接通관객), 교류상하적(交流上下的) 음양(陰陽), 교제심신(交제心신), 조절병교제수화(조절병交제水火), 창달기기(창달기기), 접통경락혈맥등적성효(接通경絡血맥等的成效). 인차타확장료'토법'적치료범위(因此他擴장了'吐法'的治료范圍). 본논문관우장씨적'토법'(本논文관于장氏的'吐法'), 개념(槪念), 방법급종류(方法及종류), 규율(규律), 통토적치료기전(通吐的治료기전), 금기(禁忌), 조선적방면래진행정리(조宣的方面래진行整理), 보고(報告).

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A CLINICAL STUDY OF THE TYPE OF DISEASE AND SYMPTOM ACCORDING TO SASANG CONSTITUTION CLASSIFICATION (체질진단분류(體質診斷分類)에 따른 질병(疾病) 및 증상유형(症狀類型)에 관한 임상적(臨床的) 연구(硏究) II (문진표를 중심으로))

  • Kim, Young-woo;Kim, jing-weon
    • Journal of Sasang Constitution and Immune Medicine
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    • v.11 no.1
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    • pp.119-135
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    • 1999
  • The object of this study is 196 patients who had been treated in the Oriental Medical Hospital at Dong Eui Medical Center during 33 months from January 1996,3 to June 1998,11. We proceeded the judgment of Sasang Constitution by 'Questionnaire of Sasang Constitution Classification(I)' and 'Questionnaire of Sasang Constitution Classification II(QSCCII)'. The following conclusion were made in comparison with Sasang Constitution and Questionnaire about disease and style of symptoms. 1. The subject of "increase of the weight of a body(gain weight), sweatier, the body swelled out, a lame pain, more like fat food, more like salty food", has significant differences in sasang constitution classification. The frequency of Taeeum group is more than that of Soeum group and Soyang group. 2. The subject of "the complextion is bas, uncomfortable feeling in the throat, insomnia, loss of appetite, apt to be fatigued easily, gastralgia what is not connected with food, diarrhea, headache, menorrhalgia, less like fat food, more like fresh food", has significant differences in sasang constitution classification. The frequency of Soeum group is more than that of Taeeum group and Soyang group. 3. It has not significant differences, but the frequency of Soyang group is more than that of Taeeum group and Soeum group in the subject of "the cough in the disease of the respiratory organs, hypomotility of the joint in the disease of the musculo-skeletal systems, menoxenia like menorrhagia and menostaxia and itching sensation of genitals in the disease of the gynecological organs, itching or boil in the dermatological disease", and fewer in the cardio-vascular disease, urinary disease and hematic disease. The frequency of Soeum group is more than that of Taeeum group and Soyang group in the subject of "the general disease of the digestive organs, uncomfortable feeling or pain of the throat in the disease of the respiratory organs, the general hematic disease, numbness or pain of the musculo-skeletal disease, psychical disease in the psychoneurotical disease, menorrhalgia, a lump of the breasts, leukorrhea in the gynecological disease, eruption or urticaria in the dermatological disease, the general visual and auditory disease". The frequency of Taeeum group is more than that of Soyang group and Soeum group in the subject of "a hoarseness in the disease of the respiratory organs, A lame pain of the musculo-skeletal disease, neurotical disease in the psychoneurotical disease, eruption or urticaria in the dermatological disease", and fewer in the the gynecological disease.

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Clinical efficacy and safety of lamotrigine monotherapy in newly diagnosed pediatric patients with epilepsy (간질 환아에서 Lamotrigine 초기 단독 요법의 효능 및 안정성에 대한 연구)

  • Han, Ji-Hye;Oh, Jung-Eun;Kim, Sun-Jun
    • Clinical and Experimental Pediatrics
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    • v.53 no.4
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    • pp.565-570
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    • 2010
  • Purpose : To verify the efficacy and safety of lamotrigine (LTG) monotherapy in newly diagnosed children with epilepsy. Methods : We prospectively enrolled 148 children who had undergone LTG monotherapy at our institution between September 2002 and June 2009. Twenty-nine patients were excluded: 19 due to incomplete data and 10 were lost to follow up. The data of the remaining 119 patients was analyzed. Results : We enrolled 119 pediatric epilepsy patients (aged 2.8-19.3 years; 66 males and 53 females) in this study. Out of 119 patients, 29 (25.2%) had generalized epilepsy and 90 (74.8%) had partial epilepsy. The responses of seizure reduction were as follows: Seizure freedom (no seizure attack for at least 6 months) in 87/111 (78.4%, n=111) patients; partial response (reduced seizure frequency compared to baseline) in 13 (11.7%) patients; and persistent seizure in 11 (9.9%) patients. The seizure freedom rate was in 81.6% in patients with partial seizure (75.9% for complex partial seizure and 90.9% for benign rolandic epilepsy) and 44.8% in patients with generalized epilepsy (30.0% for absence seizure, 35.7% for juvenile myoclonic epilepsy patients, and 100.0% for idiopathic generalized epilepsy patients). Adverse reactions were reported in 17 (14.3%) patients, and 8 patients (6.7%) discontinued LTG because of rash and tic. No patient experienced severe adverse reaction such as Stevens-Johnson syndrome. Conclusion : LTG showed excellent therapeutic response and had few significant adverse effects. Our findings report may contribute in promoting the use of LTG monotherapy in epileptic children.

A Study on the Visual Preference of Users according to the Location of Benches at Urban Community Parks (도시공원에서 벤치의 배치장소에 따른 이용자의 시각적 선호도에 관한 연구)

  • 유상완;문석기;권상준
    • Archives of design research
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    • v.13 no.2
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    • pp.95-102
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    • 2000
  • The purpose of this study is to find out what is the preference of users according to the location of benches at urban community parks. This location of benches is seperated into 4 patterns according to arranging pattern of water space, a walk, pergola and shelter, greenspace. To investigate the visual preference is examined by analyzing visual volume of 4 patterns. Results are as follows; 1. Factor analysis by the total data showed that 5 factors explain 60.40 percent of total variance of the location of bench visual character. They were classified by the sensitive factor, visual factor, physical-individual factor, distinct factor, density factor. Among 5 factors, the sensitive factor which represented psychological reaction was appreciated to be highest. 2. Most of 20 items showed the following scores of mean values in sementic differential experiment : Spot 1->Spot 4-> 2-> 3. The mean values between arrangement place locational differences showed significantly, that could explain to be a violent contrast between the natural factors(weater space, green space, etc) and the artificial factors (around of pergola, shelter, etc)

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A Study on the Convergence Marketing of Pursuing Value and Beauty Service in Accordance with Men's Acceptance of Information about Beauty Care (남성들의 외모관리 정보수용도에 따른 추구가치와 뷰티서비스 융합마케팅 연구)

  • Kim, Hye-Kyun
    • Journal of Digital Convergence
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    • v.13 no.10
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    • pp.569-578
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    • 2015
  • With much changes in men's appearance style to pursue, beauty care activities, and pursuing value, it has been required to have researches on it. This study analyzed men's acceptance of information about beauty care and also the characteristics of each pursuing value. An online survey was conducted targeting about 500 male office workers in Seoul. In the results of the study, the pursuit of the practical value of five beauty care activities was the highest while the aesthetic value was very differently shown in accordance with the types of beauty care activities, compared to two other values. Contrary to other styles, especially, the acceptance of the skin care style was influenced by the sociocultural value, practical value, and aesthetic value. Especially, the passivity of the aesthetic value and the emphasis on the practical and sociocultural values were shown. The hair care was influenced by the practical value while the plastic surgery was influenced by the aesthetic value. In the care style area, the acceptance of skin care was only influenced by the pursuit of complex values. Regarding the marketing of each care style, the large-scale marketing campaign would be effective for the hair care while it would be necessary to seek for more aesthetic campaigns for the plastic surgery business.