• Title/Summary/Keyword: 플루

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Effects of Aronia melanocarpa and Korean Red Ginseng Ethanol Extracts Combination on Cytotoxicity induced by Fludarabine, a DNA Chain Terminating Anti-Cancer Drug (DNA 사슬 종결형 항암제인 플루다라빈에 의해 유도된 세포독성에 대한 아로니아-홍삼 에탄올 혼합 추출물의 효과)

  • Kim, Min Seob;Chung, You Heon;Oh, Hong Geun;Park, Jong Kun
    • The Korean Journal of Food And Nutrition
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    • v.30 no.4
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    • pp.673-680
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    • 2017
  • Fludarabine, a chain terminating anti-cancer drug, is a purine analogue that causes DNA strand breaks in normal cells. In this study, we determined if A. melanocarpa and Korean red ginseng extract mixture reduce cytotoxicity of fludarabine. Treatment of HaCaT cells with $10{\mu}M$ of fludarabine for 24 hours decreased cell viability and increased DNA strand breaks. Treatment of A. melanocarpa and Korean red ginseng extract mixture for 24 hours increased cell viability as compared with single extract treatment. The protective effect of these extracts on cell activity increased in a concentration-dependent manner. DNA strand breaks induced by fludarabine decreased as concentration of extract mixture increased. p-H2AX level, a marker of DNA strand breakage, decreased depending on the concentration of extract mixture. The effect of mixed extract of A. melanocarpa and Korean red ginseng on DNA damage is due to the anti-oxidative effect of A. melanocarpa and signal transmission through glucocorticoid receptor upon binding of saponin of Korean red ginseng.

A Study on the Radius of Curvature of Concave Optical Fiber Tips fabricated by Laser-Induced Photothermal Effect (레이저 유도 광열 효과를 이용하여 제작된 오목한 광섬유 팁의 곡률 반경에 관한 연구)

  • Choi, Ji-Won;Son, Gyeong-Ho;Yu, Kyoung-Sik
    • The Journal of the Korea institute of electronic communication sciences
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    • v.14 no.5
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    • pp.871-876
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    • 2019
  • We fabricated concave optical fiber tips using hydrofluoric acid solution and photothermal effect induced by $1.55{\mu}m$ wavelength laser applied to an optical fiber. The radius of curvature of the concave optical fiber tips fabricated with different applied laser power, etching time, and concentration of hydrofluoric acid was measured with an optical microscope. Then, we analyzed how the radius of curvature changes for those three variables. In addition, the reliability of the measurement method using a microscope was verified through a free spectral range(FSR) and a scanning electron microscope(SEM). Through this paper, the radius of curvature can be adjusted by the variables of the fabrication process of concave optical fiber tips; thus, it is overcoming the limitations of conventional optical fiber etching methods using hydrofluoric acid solutions.

Performance Analysis of Friction Pendulum System using PVDF/MgO Friction Material (PVDF/MgO 마찰재를 이용한 마찰면진장치의 성능 분석)

  • Kim, Sung-Jo;Kim, Ji-Su;Han, Tong-Seok
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.34 no.4
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    • pp.213-219
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    • 2021
  • Polytetrafluoroethylene (PTFE) is a commercialized friction material in friction pendulum systems used for earthquake hazard mitigation in structures, and it has excellent chemical resistance and frictional performance. However, PTFE has a relatively low wear resistance for the friction pendulum systems in service. As an alternative to PTFE, a cost-effective frictional material, polyvinylidene fluoride (PVDF) strengthened by magnesium oxide (MgO), with enhanced wear resistance performance is proposed in this study. The frictional performance of the developed PVDF/MgO was evaluated through experiments and compared with that of PTFE. Accordingly, a friction pendulum system was designed using the measured friction coefficient. The performance of this friction pendulum system was evaluated via nonlinear time history analyses of bridges. Subsequently, the plausibility of using PVDF/MgO as an alternative to PTFE as a friction material for friction pendulum systems was discussed.

Who is to Blame for Infection?: Emotional Discourse in Editorial Articles during the Emerging Infectious Diseases Epidemics in Korea (감염병과 감정: 신종감염병에 관한 대중매체의 메시지와 공포, 분노 감정)

  • Kim, Jongwoo;Kang, Jiwoong
    • The Journal of the Korea Contents Association
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    • v.21 no.12
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    • pp.816-827
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    • 2021
  • The purpose of this study is to understand the relationship between fear and anger emotions in the discourse produced by the media during the period of major emerging infectious diseases (SARS, Swine Flu, MERS, and COVID-19) that occurred since 2000 in Korea. The researcher collected editorial articles of the major daily newspaper after a significant epidemic of new infectious diseases and analyzed them using the Extended Parallel Processing Model (EPPM) and text mining techniques. In all epidemic times, fear appears stronger than anger, but the smaller the fear, the greater the risk control message is produced. In detail, fear emerges strongly in the discourse of the risk of infectious diseases or the economic crisis. Anger appears strong when the government's quarantine failures, groups where group infections occurred, and concealing information about infectious diseases. In this process, anger is strongly expressed against the factors that threaten the safety of society. Anger is also an emotion that can justify strong quarantine, but it can be the basis for discourse on minority hate. In this respect, anger is a two-sided emotion, so it must be handled carefully in the media.

Material Life Cycle Assessment on Mg2NiHx-CaF2 Composites (Mg2NiHx-CaF2 수소 저장 복합체의 물질 전과정 평가)

  • HWANG, JUNE-HYEON;SHIN, HYO-WON;HONG, TAE-WHAN
    • Journal of Hydrogen and New Energy
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    • v.33 no.2
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    • pp.148-157
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    • 2022
  • Research on hydrogen storage is active to properly deal with hydrogen, which is considered a next-generation energy medium. In particular, research on metal hydride with excellent safety and energy efficiency has attracted attention, and among them, magnesium-based hydrogen storage alloys have been studied for a long time due to their high storage density, low cost, and abundance. However, Mg-based alloys require high temperature conditions due to strong binding enthalpy, and have many difficulties due to slow hydrogenation kinetics and reduction in hydrogen storage capacity due to oxidation, and various strategies have been proposed for this. This research manufactured Mg2Ni to improve hydrogenation kinetics and synthesize about 5, 10, 20 wt% of CaF2 as a catalyst for controlling oxidation. Mg2NiHx-CaF2 produced by hydrogen induced mechanical alloying analyzed hydrogenation kinetics through an automatic PCT measurement system under conditions of 423 K, 523 K, and 623 K. In addition, material life cycle assessment was conducted through Gabi software and CML 2001 and Eco-Indicator 99' methodology, and the environmental impact characteristics of the manufacturing process of the composites were analyzed. In conclusion, it was found that the effects of resource depletion (ARD) and fossil fuels had a higher burden than other impact categories.

The Causes of the boom in the container shipping industry triggered COVID-19: Focuses on Demand and Supply Side (COVID-19 발 컨테이너 해운경기 호황의 원인 분석: 수요와 공급 측면에서)

  • Lee, Tae-Hwee;Kim, Soo-Kyung
    • Journal of Korea Port Economic Association
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    • v.39 no.2
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    • pp.195-204
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    • 2023
  • In this study, the causes of the boom in the container shipping industry pointed out by the media were analyzed. As a result of the analysis, it was found that on the supply side, shipping companies mooring ships in response to IMO environmental regulations caused a rise in freight rates due to 'ships that could not be operated' even if demand increased. In terms of demand, it was determined that the claim that social distancing promoted purchases and increased demand was somewhat unfounded. The reason is that the relationship between social distancing and rising fares is weak.

Synthesis and Investigation of LiVPO4O1-xFxvia Control of the Fluorine Content for Cathode of Lithium-ion Batteries (플루오린 함량 제어를 통한 LiVPO4O1-xFx 합성 및 리튬 이차전지 양극소재 전기화학 특성 분석)

  • Minkyung Kim;Dong-hee Lee;Changyu Yeo;Sooyeon Choi;Chiwon Choi;Hyunmin Yoon
    • Journal of Powder Materials
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    • v.30 no.6
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    • pp.516-520
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    • 2023
  • Highly safe lithium-ion batteries (LIBs) are required for large-scale applications such as electrical vehicles and energy storage systems. A highly stable cathode is essential for the development of safe LIBs. LiFePO4 is one of the most stable cathodes because of its stable structure and strong bonding between P and O. However, it has a lower energy density than lithium transition metal oxides. To investigate the high energy density of phosphate materials, vanadium phosphates were investigated. Vanadium enables multiple redox reactions as well as high redox potentials. LiVPO4O has two redox reactions (V5+/V4+/V3+) but low electrochemical activity. In this study, LiVPO4O is doped with fluorine to improve its electrochemical activity and increase its operational redox potential. With increasing fluorine content in LiVPO4O1-xFx, the local vanadium structure changed as the vanadium oxidation state changed. In addition, the operating potential increased with increasing fluorine content. Thus, it was confirmed that fluorine doping leads to a strong inductive effect and high operating voltage, which helps improve the energy density of the cathode materials.

Electrical and Optical Properties of Fluorine-Doped Tin Oxide Films Fabricated at Different Substrate Rotating Speeds during Ultrasonic Spray Pyrolysis Deposition (초음파 분무 열분해 증착 중 기판 회전 속도에 따른 플루오린 도핑 된 주석산화물 막의 전기적 및 광학적 특성)

  • Ki-Won Lee;yeong-Hun Jo;Hyo-Jin Ahn
    • Korean Journal of Materials Research
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    • v.34 no.1
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    • pp.55-62
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    • 2024
  • Fluorine-doped tin oxide (FTO) has been used as a representative transparent conductive oxide (TCO) in various optoelectronic applications, including light emitting diodes, solar cells, photo-detectors, and electrochromic devices. The FTO plays an important role in providing electron transfer between active layers and external circuits while maintaining high transmittance in the devices. Herein, we report the effects of substrate rotation speed on the electrical and optical properties of FTO films during ultrasonic spray pyrolysis deposition (USPD). The substrate rotation speeds were adjusted to 2, 6, 10, and 14 rpm. As the substrate rotation speed increased from 2 to 14 rpm, the FTO films exhibited different film morphologies, including crystallite size, surface roughness, crystal texture, and film thickness. This FTO film engineering can be attributed to the variable nucleation and growth behaviors of FTO crystallites according to substrate rotation speeds during USPD. Among the FTO films with different substrate rotation speeds, the FTO film fabricated at 6 rpm showed the best optimized TCO characteristics when considering both electrical (sheet resistance of 13.73 Ω/□) and optical (average transmittance of 86.76 % at 400~700 nm) properties with a figure of merit (0.018 Ω-1).

A Study of Fine Dust Blocking Network Using Electrospinning Nanofiber Deposition (전기방사를 활용한 나노섬유 증착 미세먼지 방진망에 관한 연구)

  • Chan Young Lee;Sang Min Lee;Hyeon Jin Song;Jae Jun Lee;Young Soon Kim;Hong Gun Kim
    • Journal of The Korean Institute of Defense Technology
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    • v.6 no.1
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    • pp.13-18
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    • 2024
  • While fine dust is currently spreading around the world, fine dust is so small that it easily enters indoors and deteriorates indoor air quality, so it is an essential issue that must be solved to maintain cleanliness and improve air quality in households. Research on nanoradiation technology is continuously being conducted to effectively block fine dust and secure air permeability and dust collection rate. In this study, a PVDF fine dust dust-proof net was manufactured through electrospinning, and an experiment was conducted to confirm the external environmental resistance and indoor air quality improvement efficiency of the manufactured dust-proof net. It was verified that this dustproof net can be a practical alternative to effectively block fine dust and prevent diseases caused by fine dust.

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Soil-blending Effect of Eggshell Powder on the Control of Club root Disease and the Growth of Chinese Cabbage in the Field (배추 무사마귀병 발병 억제 및 생육증진을 위한 달걀껍질 토양혼화처리 효과)

  • Gao, Yuliang;Kim, Byeong-Kwan;Lim, Tae-Heon;Li, Kui-Hua;Paek, Kee-Yoeup;Cha, Byeong-Jin
    • Research in Plant Disease
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    • v.15 no.2
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    • pp.106-111
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    • 2009
  • Before transplanting Chinese cabbage seedlings, two kinds of eggshell powder were blended into the soil of cabbage field where the club root pathogen, Plasmodiophora brassicae, was infested. The incidence of clubroot disease, the shoot and root growth of cabbages, and soil pH were examined four times at 10 to 13 days interval from transplanting Chinese cabbage. As results, the cabbages treated with eggshell powder without membrane showed the fastest growth in above ground part, and the lowest disease index for clubroot disease. The cabbages treated with eggshell powder with membrane showed better growth than the cabbages of non-treated check, but lower growth than those treated with eggshell powder without membrane. Soil pH started to increase from 3 weeks after soil blending of eggshell powder, and it reached to above 8.0. However, the soil pH of non-treated check stayed at around 6.8. In the experiment to compare the effect of eggshell powder with other calcium compounds, soil-blending of $CaCO_3$ resulted the lowest disease incidence of 1.7 and the registered fungicide, 'flusulfamide', and the resistant variety 'CR Green cabbage' followed with the incidence of 1.9. Cabbages of non-treated check scored the highest disease incidence, 3.4, and that of eggshell powder without membrane was as high as 2.7. However, the growth of Chinese cabbage showed the different pattern to the disease incidence. Chinese cabbages treated with eggshell without membrane recorded the highest average growth, around 2.1 kg. On the other hand, the average growth of CR Green Chinese cabbage was about 2.0 kg, that of flusulfamide-treatment plot was 1.7, and that of non-treated check was as low as 1.3 kg. Soil blending of eggshell powder without membrane did not inhibit the development of clubroot, but increased the growth of cabbage to a great extent. Therefore, it was confirmed that soil blending of eggshell powder before transplanting makes the Chinese cabbage culture possible even in the field infested with club root pathogen.