• Applied Biological Chemistry
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• v.38 no.1
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• pp.37-41
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• 1995

The effect of age on the metabolism of progesterone was studied in the rat brain. Metabolic activity was more active in minced tissues than total homogenates. The activity of progesterone $5{\alpha}-reductase(s)$ was increased during postnatal periods(between 5 and 14 days after birth) and thereafter steadily decreased up to the one-fourth level of the fetus. When $5{\alpha}-dihydroprogesterone$ was incubated with brain tissues of various ages, the change in the activity of $3{\alpha}-hydroxysteroid$ oxidoreductase$(3{\alpha}-HSOR)$ was similar to that of $5{\alpha}-reductase(s)$. These results suggest that the reduced formation of total $5{\alpha}-reduced$metabolites was due to the decreased activities of $5{\alpha}-reductase(s)$ and $3{\alpha}-HSOR$. However the level of $3{\beta}-HSOR$ remained constant regardless of the age.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2002.05a
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• pp.1085-1092
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• 2002

수십만명의 대입응시자와 대학입학을 준비하는 수백만명의 초중고등학교 학생들에게 공정한 경쟁의 규칙과 측정방법을 마련하여 적응하는 것은 매우 중요하다. 현행 대학입학 수학능력 시험에서 각 영역별 표준점수는 응시계열인 인문계열, 자연계열, 예체능계열로 나누어 각 계열의 평균과 표준편차를 사용하여 계산한다. 따라서 동일한 점수도 어느 응시계열에 속하는가에 따라 표준점수가 달라지게 되며, 상이한 표준점수를 사용하여 대등한 경쟁을 하는 경우가 있어 불공정성이 제기된다. 비록 변환표준점수로 조정하여 계열간 불공정이 어느 정도 조정되지만, 자신의 점수에 비하여 집단의 평균점수가 낮을수록 변환표준점수가 증가하게 되므로 계열선택의 영향이 없다고 보기 어렵다. 이러한 결과로 유리한 계열로 대거 이동하는 현상이 나타나고 있다. 본 연구는 대학입학에 필수적인 대학입학 수학능력시험에서 계열간 실력차이를 보정하여 공정한 경쟁을 가능하게 하는 표준점수 계산방법을 제시하였다. 또한 모든 과목이 선택과목이 되는 2005학년도부터 시행될 수학능력시험에서 과목간 표준점수를 보정하는 방법을 제시하였다 본 연구는 결론을 도출하는데 있어 응시자들간 표준점수의 차이는 응시과목에 따라 달라지지 않는다는 과목의 동질성을 가정하였다. 응시과목의 동질성 가정하에서 집단간의 표준점수를 보정하는 방식은 동일한 시험문제로 각 집단이 시험을 보는 경우 집단간의 차이만큼을 표준점수에 합하여 보정하고, 각 집단이 고유하게 응시하는 시험과목은 공통과목의 차이만큼을 각 집단에 보정하여 주는 것이다. 과목간에 표준점수를 보정하는 방식은 해당과목에 응시한 응시자들이 다른 과목에서 획득한 표준점수의 평균치로보정하는 것이다.하기 위해서, 기업간 프로세스 협업(collaboration) 부분의 데이터 및 서식, 이를 취급하는 기능과 프로세스에 대란 분석을 통해 업무 프로세스 모델링 방법론과 관련한 모델링 지침 및 메타모델을 이용한 표준 업무 프로세스 모델을 개발하여 기업간 업무 프로세스 표준화에 대한 체계적인 관리에 대한 방안을 연구하고자 한다.의Bullwhip effect를 감소시킬 수 있는 장점이 있다. 동시에 이것은 향후 e-Business 시스템 구축을 위한 기본 인프라 역할을 수행할 수 있게 된다. 많았고 년도에 따른 변화는 보이지 않았다. 스키손상의 발생빈도는 초기에 비하여 점차 감소하는 경향을 보였으며, 손상의 특성도 부위별, 연령별로 다양한 변화를 나타내었다.해가능성을 가진 균이 상당수 검출되므로 원료의 수송, 김치의 제조 및 유통과정에서 병원균에 대한 오염방지에 유의하여야 할 것이다. 확인할 수 있었다. 이상의 결과에 의하면 고농도의 유기물이 함유된 음식물쓰레기는 Hybrid Anaerobic Reactor (HAR)를 이용하여 HRT 30일 정도에서 충분히 직접 혐기성처리가 가능하며, 이때 발생된 $CH_{4}$를 회수하여 이용하면 대체에너지원으로 활용 가치가 높은 것으로 판단된다./207), $99.2\%$(238/240), $98.5\%$(133/135) 및 $100\%$ (313)였다. 각각 두 개의 요골동맥과 우내흉동맥에서 부분협착이나 경쟁혈류가 관찰되었다. 결론: 동맥 도관만을 이용한 Off pump CABG를 시행하여 감염의 위험성을 증가시키지 않으면서 영구적인 신경학적 합병증을 일으

• Clinical and Experimental Pediatrics
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• v.51 no.1
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• pp.1-25
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• 2008

Purpose : Since 1967, The Korean Pediatric Society and Korean Government have developed Korean Growth Standards every 10 years. Last version was published in 1998. During past 40 years, Korean Growth Standards were mainly descriptive charts without any systematic nor statistical standardization. With the global epidemic of obesity, many authorities such as World Health Organization (WHO) and United States' Centers for Disease Control (CDC) have been changed their principles of growth charts to cope with the situations like ours. This article summarizes and reviews the whole developmental process of new 2007 Korean Growth Charts with discussion. Methods : With the initiative of Division of Chronic Disease Surveillance in Korea Centers for Disease Control and Prevention, we have performed new national survey for the development of new Standards in 2005 and identified marked increase of childhood obesity and plateau of secular increment of final height in late adolescents. We have developed new Growth Standards via adapting several innovative methods, including standardization of all available raw data, which were acquired in 1997 and 2005 national survey and full application of LMS method. Results : We could get new standardized charts; weight-for-age, length/height-for-age, weight-for-height, head circumference-for-age and BMI-for-age. Other non-standardized charts based on 2005 survey data were also published; waist circumference-for-age, mid-arm circumference-for-age, chest circumference-for-age and skinfold-for-age. Clinical guideline was also developed. Conclusion : Developmental process and results of new Korean Growth Charts are comparable with other internationally well-known Growth Standards, WHO 2006 Growth Standards and CDC Growth Charts. 2007 Korean Growth Charts are relevant especially in Korea and Korean ethnic groups.

• Journal of Nutrition and Health
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• v.42 no.7
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• pp.615-621
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• 2009

This study was conducted to evaluate the change of nutritional status and to analyze related factors in hospitalized tuberculosis (TB) patients during their hospitalization. The subjects were 398 men patients (mean age: 47.3 ${\pm}$ 14.4 y) who had hospitalized more than 3 months at TB hospital located in Seoul. The anthropometric and blood biochemical indices were measured, and dietary intakes were assessed. At the time of admission the body weight of subjects was about 76% of the average body weight of Korean men with same age, Body mass index (BMI) of subjects was 18.5 kg/$m^2$, and 53.8% of subjects were under weight status. Average level of blood hemoglobin and hematocrit of subjects was lower than the normal value. After 3 months of hospitalization period, the body weight and body mass index were significantly increased compared to admission by 3.9 kg (7.41%) and 1.4 kg/$m^2$ (7.61%)(p < 0.001), respectively. Blood levels of hemoglobin, hematocrit, albumin, and total protein were also significantly increased after 3 months of hospitalization period compared to admission (p < 0.001). The increment in the body weight and blood indices was significantly higher in below 29 years group than over 60 years group (p < 0.05). The increment in the body weight and body mass index was significantly higher in the under-body weight group compared to the normal-body weight group (p < 0.05). In conclusion the body weight and body mass index of subjects were significantly increased after 3 months of hospitalization period, and the age and body weight of subjects at admission were supposed to influence the degree of change in the nutritional status.

• The korean journal of orthodontics
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• v.23 no.2 s.41
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• pp.249-261
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• 1993

This study was conducted to examine the growth change in external nose according to age which plays an important role in determining the facial profile, by analysing the biennial serial lateral cephalograms of 20 males and 20 females of mean 8.5 years old to 16.5 years old who have a normal occlusion. The results of this study were summarized as follows. $\cdot$ Both mean and standard deviation were obtained according to each item, sex and age for the male and female. $\cdot$ Nose heights of the male and female increased with increase in their age. The upper to lower nose height ratio somewhat decreased for both male and female with increase of age. The mean ratio was 3.69 : 1 for the male, respectively, and 3.83 : 1 for the female during this study．$\cdot$ The nose depth indicated the most significant increase of all items according to the increase of age, while the sagittal depth inicated higher value for the female than that of the male in the most age groups. $\cdot$ The nose inclination did not show a remarkable change during this study. $\cdot$ The proportions of growth completed at the earliest age showed the highest percentage for sagittal depth(male : $87.14\%$ & female : $91.29\%$). Also, the male indicated the lowest percentage in lower nose height $(73.04\%)$, while the female did the lowest in nose depth$(79.09\%)$. $\cdot$ There was shown the variable of the greatest correlation between the upper nose inclination and nose depth. $\cdot$ From this study, the whole external nasal growth was occurred downward and forward which was more frequent for forward growth than vertical growth.

• Journal of the Korean Society of Clothing and Textiles
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• v.27 no.1
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• pp.88-99
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• 2003

The body changes of the elderly women are the forward tilt of the neck and shoulder point shrinkage of the spinal column, and protrusive abdomen. Unfortunately, few data based on body measurements for elderly women existed and a few studies are limited to the body figure of the elderly women. If these changes are not applied to the manufacturing of the clothing, almost of the elderly women will be unfitted with their clothing. So to improve the fitting of the elderly women, it is necessary to use the standard size systems for elderly women. This report is the first study to develop the standard tables of body measurements to be used for improving the fit of garments and patterns for women aged 60 and older. This study drew from anthropometric measurements of 337 and photographic measurements of 276 women aged 60 and older. It described the protocol of anthropometric measurement, the comparison between the measured data and the data on which National anthropometric survey of Korea 1997 is based, and the development of body measurement standard tables for elderly women. And we also considered the regional difference of body dimensions in order to develop the national size standards for elderly women. Further study would include the classification of body dimensions and description of each figure type for sizing apparel of women aged 60 and older.

• Pediatric Infection and Vaccine
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• v.5 no.1
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• pp.128-135
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• 1998

Purpose : This study was intended to measure seropositivities and the level of mumps- and rubella-specific IgG of MMR vaccinees from 12 to 17 years of age in Korea. Materials and Methods : From May 1996 to July 1996 we obtained sera from students of 1 middle and 2 high schools in Seoul, who were MMR vaccinees from 12 to 17 years of age and had no evidence of immunodeficiency. These 216 study population include 110 males and 106 females. Mumps- and rubella-specific IgG antibody levels were measured by ELISA. Cut-off values for seropositivity were 20 U(Gamma Unit) in mumps and over 0.17 in rubella. Results : 1) As age increased, seropositivities to mumps increased, being 68.4% in 12 year, 79.3% in 13 year, 72.2% in 14 year, 82.0% in 15 year, 87.5% in 16 year, 87.0% in 17 year, which however has no statistical significance. 2) As age increased, the level of mumps-specific IgG antibody(mean+standard deviation, GU) increased, being $52.0{\pm}49.2$ in 12 year, $65.9{\pm}51.4$ in 13 year, $71.1{\pm}66.0$ in 14 year, $67.8{\pm}53.6$ in 15 year, $82.8{\pm}67.8$ in 16 year, $92.0{\pm}68.9$ in 17 year, which however has no statistical significance. 3) As age increased, seropositivities of rubella-specific IgG increased significantly, being 26.3% in 12 year, 20.7% in 13 year, 50.0% in 14 year, 67.2% in 15 year, 66.7% in 16 year, 65.2% in 17 year(P<0.001). 4) As age increased, rubella-specific IgG increased significantly, being $0.13{\pm}0.145$ in 12 year, $0.087{\pm}0.101$ in 13 year, $0.194{\pm}0.168$ in 14 year, $0.260{\pm}0.187$ in 15 year, $0.305{\pm}0.213$ in 16 year, $0.325{\pm}0.221$ in 17 year(P<0.001). There was positive correlation between age and rubella-specific IgG titer(rubella-specific $IgG=0.0517{\times}age-0.5586$, r=0.3752, P<0.001). Conclusion : In adolescent, seropositivities and the level of mumps-specific IgG remained relatively high, but approximately 20% of study population showed seronegativity. Seropositivities and the level of rubella-specific IgG showed the lowest level at 13 years of age and were increased with age after 14 years of age. Further evaluation may be needed to elucidate the cause of these changes of rubella-specific IgG.

• Journal of Digital Convergence
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• v.12 no.9
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• pp.283-290
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• 2014

Recently, As the prevalence of precocious is increased in Korea This study was evaluated the physical growth and female sex hormone characteristics of girls with Idiopathic precocious puberty. Retrospective analysis about the medical record of 113 girls for evaluation of signs of precocious puberty except for organic causes was done. Physical growth features and Female sexual hormone were analyzed. Height SDS and Weight SDS were significantly increased in true sexual precocity compared to pseudo sexual precocity. Hormone studies showed that the level of basal LH, FSH, E2 was significantly higher in true precocious puberty. The finding of this study suggest that we need to develop intervention about physical and psychological problems for precocious puberty girls.

• The Journal of Korean Physical Therapy
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• v.13 no.1
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• pp.97-105
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• 2001

Objectives: The objective of this study was to investigate the Associated factors of bone mineral density in postmenopausal was measured for 36 normal in the women from July 14.2000 to august 24,2000. Methods: The data were collected from women who visited Physical Examination Center of a Catholic university hospital located in Taegu. Bone mineral density(BMD) of lumbar spine was measured using energy absorptiometry. Results: The bone mineral density of the lumbar spine decreased with aging. The bone mineral density of the lumbar spine increased with number of delivery and number of abortion decreased. The mean bone mineral density of the lumbar spine of postmenopausal women in age less than 50 and 50 ${\sim}$ 59 were 0.79 g/c$m^2$, the lumbar spine of postmenopausal women in age greater than 60 was 0.69 g/c$m^2$. The mean bone mineral density of the lumbar spine of postmenopausal women in mean age 56.1. Conclusions: In the multiple regression of risk factors to bone mineral density(BMD) of lumbar spine were correlated with bone mineral density T-scores(p<0.05). Osteoporosis is a major public health problem among the elderly, demanding effective strategic approach for prevention and treatment.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.9 no.3
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• pp.237-243
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• 2015

As one of the most widely used assistive technology devices for the disabled in Korea, the powered wheelchair conforms to KS P ISO 7176-5 standard size which uses original version of international standard, ISO 7176-5 without technological modification. However, the international standard is not suitable for the disabled in Korea because it defines the size of wheelchair based on the body size of foreigners, which causes imbalanced posture due to limitation of movement or rotation of pelvis, pressure ulcer incidence due to excessive pressure on the thigh or popliteal space and calf, and safety of reduction due to improper posture. This study suggested the guidance of size for powered wheelchair based on human body size examined by Korean Agency for Technology and Standards, showing a great difference from the size defined in KS P ISO 7176-5 and accordingly redefinition for the size of powered wheelchair is needed.