• 센서학회지
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• 제7권4호
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• pp.279-284
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• 1998

수용액에서 자당의 농도 변화를 감지하기 위한 센서개발을 목적으로 하여, 금박막을 센서칩으로 사용한 SPR(surface plasmon resonance) 센서시스템을 구성하였다. 센서칩 제작시 금박막의 특성조건은 SPR 현상에 매우 큰 영향을 미치므로, 센서 제작의 최적화를 위해 특성을 분석하여 두께 약 $545\;{\AA}$, 표면 평균 거칠기 약 $3\;{\AA}$이 되도록 균일하게 제작하였다. 이렇게 제작된 금박막 센서칩의 공명각은 $43.75^{\circ}$ 이었으며, $0{\sim}40\;wt%$ 농도의 자당 수용액을 측정한 결과 기존의 알려진 자당 센서에 비해 빠른 응답특성과 선형적인 공명특성을 얻을 수 있었다.

• 한국고분자학회지:고분자과학과기술
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• 제26권1호
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• pp.9-15
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• 2015

• 센서학회지
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• 제17권2호
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• pp.95-99
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• 2008

Various etching methods of optical fiber and formation of metal nano particles on the optical fiber have been proposed for fabrication of fiber optic localized surface plasmon resonance (FO LSPR) biosensors. Different types of etched optical fiber are possible by removing the cladding of optical fiber using HF (hydrofluoric acid) solution and BHF (buffered hydrofluoric acid) solution, which results in improved surface roughness when BHF solution is used. Localized surface plasmon can be formed and measured by formation of silver and gold nano particles on the etched optical fiber. The characteristics of the etched optical fiber and metal nano particles on the etched surface of the optical fiber play a key role in dictating the sensitivity of the LSPR sensors, so that the proposed results can be expected to be applied for related research on fiber optic based biosensors.

• 센서학회지
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• 제18권3호
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• pp.226-233
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• 2009

In this study, the optical properties of localized surface plasmon resonance sensor using optical fiber was analyzed as the variation of a size and surface density of gold nano particles on the etched optical fiber surface. It is shown that a size and surface density of gold nano particles on optical fiber surface are controlled by $Na_3$ citrate quantity and pH of gold colloid solution. To measure the sensitivity, peak wavelength of absorbance spectrum was detected as the reflective index of the solution. The sensor sensitivity is linearly dependent on the size and surface densities of gold nano particles from the results of optical experiments.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2018년도 춘계학술대회 논문집
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• pp.85.2-85.2
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• 2018

금속 나노구조체에서의 localized surface plasmon resonance와 surface-enhanced Raman scattering 현상은 센서를 비롯한 다양한 응용분야를 가지고 있다. 나노구조체 array 형성을 위한 대표적인 top-down 방식인 e-beam lithography 공정은 제조비용이 매우 높고 대량생산 및 대면적화에도 한계가 있기에 polystyrene(PS) bead의 self-assembly를 이용한 nanosphere lithography와 같은 bottom-up 방식이 폭넓게 연구되고 있다. Closed-packing된 PS bead의 monolayer를 얻기 위해서는 기판의 친수성 처리가 필요한데, 기존의 많은 연구에서는 기판의 표면개질에 화학적 공정을 이용하고 있다. 하지만 이는 기판 선택의 자유도를 떨어뜨리는 원인이 된다. 금속이나 실리콘 기판에서는 산성 용액을 이용한 화학적 처리방법을 적용할 수 있지만 SU-8과 같은 감광액 및 폴리머 기판에서는 산에 대한 내구성이 떨어져 화학적 공정의 도입이 불가능 하기 때문이다. 본 연구에서는 이러한 한계점을 극복하기 위해 $UV-O_3$ 공정으로 친수성 처리된 다양한 기판에서 spin coating을 통한 PS monolayer를 제조하였는데, UV 램프의 에너지 조절을 통해 기판에 붙어있는 유기물들을 효과적으로 제거할 수 있었고 $O_3$ 생성 및 분해 과정에서 기판 표면에 친수성 화학 작용기를 생성시킬 수 있었다. 제조된 PS layer를 mask로 사용하여 Ag, Al, Au 등 다양한 나노구조체 array를 형성하여 array 주기에 따른 플라즈몬 공명 특성을 분석하였다. 레이저 조사로 나노구조체의 형상을 변화시킴으로써 동일한 물질과 주기를 가진 array에서도 플라즈몬 특성의 변조가 가능함을 확인하였는데, 이는 금속 나노구조체의 응용측면에서 매우 고무적인 발견이다.

• 센서학회지
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• 제13권5호
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• pp.342-349
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• 2004

SK (SPR Kinds) index, which can categorize the complicated measurement methods of surface plasmon resonance by simple method, has been proposed and verified. SK index is composed of three digits, where each digit presents the type of immobilized ligand, the type of illumination and the kinds of varying parameter, sequentially. The measurement method of (33#) series among SK indices shows the possibility of the multi-sensing capability, by which the response of 2-dimensional array of immobilized ligands can be detected simultaneously. The proposed possibility of multi-sensing capability has been verified by the modeling that is based on Fresnel reflection model.

• 센서학회지
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• 제15권5호
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• pp.347-351
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• 2006

A novel surface plasmon resonance sensor, which can measure 2-dimensional array of immobilized ligands without using imaging devices such as CCD, has been proposed. Regular surface plasmon resonance can be directly used due to the insertion of additional layers with different thickness, on which each ligands are immobilized. Surface plasmon resonance signals are separated depending on the thickness of additional layers. The possibility of multi-sensing capability of the proposed surface plasmon resonance sensor has been verified by the modeling that is based on Fresnel reflection model.

• 센서학회지
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• 제14권6호
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• pp.402-408
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• 2005

This paper describes the optimal design of a multi-layered surface plasmon resonance sensors to meet various specifications and improve some physical parameters. Dip 3 dB bandwidth and depth were chosen as design parameters and the objective function was the norm of the difference between design parameters and target values. The design variables are thicknesses of each layer and to obtain the design parameters, the optical admittance method was employed. The (1+1) evolution strategy was employed as an optimization tool. By applying the proposed optimization procedure to a 3-layered sensor, the optimized design variables considerably improved the 3 dB bandwidth by 4.8 nm and the dip depth by 1.1 dB.

• 센서학회지
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• 제20권2호
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• pp.107-113
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• 2011

LSPR(Localized Surface Plasmon Resonance) sensor measures the refractive index change on the sensor surface. The detection of biological reaction with the unknown refractive index needs to be converted into the signal sensitivity for the refractive index change for comparison with other measurements. To find the signal sensitivity, the three steps of signal processing are proposed, which are signal modeling, signal calibration and signal normalization of LSPR sensor. The detected signal of biotin-streptavidin interaction has been converted into unit of [RU](Resonance Unit) using the proposed method. The converted signal directly can be compared with the other sensors including commercialized one.

• 센서학회지
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• 제26권6호
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• pp.402-407
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• 2017

Characteristics of various material surface plasmon resonance (SPR) chips were investigated in angular interrogation mode and intensity interrogation mode. Among five metals, silver (Ag), gold (Au), copper (Cu), chromium (Cr) and titanium (Ti), three metals, Ag, Au and Cu were paid attention to since their characteristics can be easily analyzed in angular interrogation mode by investigating the change of their reflectance curves according to refractive index change from 1.331 to 1.335. Most of SPR chips with various configurations showed the similar property in angular interrogation mode. The application of the SPR chip made of Ag, Au and Cu or their combinations depends on their reflectance properties. In intensity interrogation mode, the operation range may be limited since the variation of the intensity was not linearly related to refractive index change ranging from 1.331 to 1.335. However, the SPR chip containing high ratio of Ag may be applicable to high sensitive detection due to their sharp reflectance curves in intensity interrogation mode.