• Journal of Technology Innovation
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• v.25 no.3
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• pp.25-50
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• 2017

Declining research competitiveness and inefficiency are constantly being raised in the National Assembly and the media for the Government-funded Research Institutes(GFRIs), which are highly dependent on government funding. These external stakeholders point to the workforce aging of the GFRIs as one of the main causes of inefficiency. They insist that the aging leads to an increase in labor costs, a discontinuity in research, a decrease in employment of new researchers, and a decrease in research competitiveness. However, the GFRIs argue that the aging is a natural phenomenon due to an increase in the age of recruitment, and even if there is an side effect, it is extremely small or even vice versa. It is interesting that there is no empirical study identifying the correlation between the workforce aging and the research performance of the GFRIs, despite the discussion. This study tracked and analyzed the changes of the research performance and the workforce for the five years from 2011 to 2015, and tried to demonstrate the correlation between the workforce aging and the research performance. As a result, we confirmed that there is an inverted U-type correlation between the aging and the papers, one of the research performance, and that the optimal age is 44.96 years. Also, we could not find any correlation between the aging and the patents.

• Clinical and Experimental Pediatrics
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• v.50 no.7
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• pp.678-685
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• 2007

Purpose : Recent reports pointed out that gonadotropin releasing hormone analogue (GnRHa) therapy alone is not so promising for improving adult height in precocious puberty. So, that we studied the growth promoting effect of combined therapy with GnRHa and growth hormone (GH) in early pubertal girls. Methods : Twenty three early pubertal girls ($9.73{\pm}1.59yr$) with predicted adult heights (PAH) below-2 standard deviation score (SDS) were included. They were divided into two groups as follows; Group I before menarche (n=19) and Group II after menarche (n=4). After combined therapy, various growth parameters were compared between two groups and between the before and after therapy. Results : Between the two groups before therapy, chronologic age (CA), growth velocity (GV), body mass index (BMI), target height (TH), PAH and serum insulin-like growth factor binding protein-3 were not different, but BA, height and difference between bone age (BA) and CA were significantly higher and insulin-like growth factor-1 (IGF-1) was marginally higher in group II. After therapy, BA still remained higher in group II, but other parameters were not different. In both groups, after therapy, the difference between BA and CA, the ratio of BA over CA, and GV were significantly decreased, but PAH, height SDS and BMI were significantly increased. Regarding IGF-1 level, a significant increase was noted in group I, but not in group II. Conclusion : With combined therapy of GnRHa and GH, PAH in early pubertal girls might be improved significantly and even approach TH. Among them, those who were before menarche might have greater potential for the height gain than those after menarche in view of IGF-1 changes during therapy.

• Korea journal of population studies
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• v.18 no.2
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• pp.1-22
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• 1995

In this paper, the methods to measure the mean age at first marriage is examined, and by analysing data of Korean women for the period 1970-1990, the differences that each methods make on measurements of the mean age at first marriage are presented. The main findings were : The Hajnal's SMAM, the most used index in studies of the pattern of marriage in Korea, was not a measure based on the marriages for a specific period. The resulting biases, in cases of 1970-1990 Korean women, were below 0.3 year in age, which can be considered small, if the changes in the pattern of marriage in these periods took into account. But the possibility of bringing larger bias cannot be excluded. Also the direction of biases was toward raising the mean age when marriage was in upward tendency. Considering the availability of data in Korea, the utilization of the simple mean or the measure from Agarwala method according to the purpose is recommendable. The mean age at first marriage by Agarwala(ASMAM) meets with the one computed from a gross nuptiality table based on the cohort's marriage rates for a specific period. The time series of the proportion single by age groups obtained from the population censuses showed high consistency. However when they were compaired with those computed from sample surveys at a same point of time, significant differences(at $\alpha$=0.05) were found in some major age groups. It was also pointed out that these differences were not caused by the problems related with the sampling frame for surveys or the survey questions.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.3
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• pp.181-187
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• 2020

Fecal calprotectin (FC) is a marker used for the differential diagnosis of inflammatory bowel disease (IBD). FC is also used to determine the effects of treatment and recurrence prediction because of its non-decomposition by bacteria, relative week stability at room temperature, and its uniform distribution within feces. Healthy male and female adults between the age of 30 and 80 living in Jeju were selected for this study. The FC concentration in the healthy control group (N=45) was distributed widely as 0~545.9 ㎍/g and showed a significant difference with age in healthy adults. The FC concentration in adults over 70 years old (80.6 years on average) was 160.3 ㎍/g. The result is approximately 10 times higher than in adults below 50 years (44 years on average), with FC concentrations at 15.88 ㎍/g. Moreover, adults over 50 years, with an average age of 59.6, had FC concentrations of 35.46 ㎍/g, which were two times higher than the below 50-year-old group, confirming the significant correlation between age and FC concentration. As the FC test is a non-invasive and cost-effective objective marker in IBD tests, a suitable cut-off value is required for different ages. This study provides the baseline data for differential diagnoses.

• 프린팅코리아
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• v.14 no.4
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• pp.54-57
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• 2014

최근 전 세계적으로 고령화가 급속히 진행되고 있는 가운데, 우리나라는 세계 최저 수준의 출산율과 최고 수준의 고령화 진행 속도로 인해 향후 경제성장이 저하될 것이라는 우려의 목소리가 커지고 있다. 세계에서 가장 빠른 속도로 '늙어가는 국가'가 된 우리나라는 생산가능인구 감소와 취업자 평균연령 상승으로 노동생산성 저하가 현실이 되고 있다. 특히 인쇄업종의 경우 산업현장에 새로 유입되는 청년은 거의 없고, 취업자의 평균연령은 매년 증가하고 있어 노동생산성 하락세가 지속되고 있다.

• The korean journal of orthodontics
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• v.25 no.4
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• pp.465-485
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• 1995

The purpose of this study is to locate the proper position of the lower occlusal plane according to individual skeletal pattern. Cephalometric films of 234 subjects of the control group, 358 of the pretreatment group and 358 of the treated group were analyzed to study proper relationships between vertical dimension ratio(VDR) and lower occlusomandibular plane angle(LOM). The control group was divided into two subgroups by the age. The first subgroup consisted of 113 subjects of the age 14 years and under and with the mean age of 10.82 years. The other subgroup consisted of 113 subjects of the age 18 years and above with the mean age of 23.76 years. The pretreatment group was divided into three subgroups by the age. The first subgroup consisted of 274 subjects of the age 14 years and under with the mean age of 11.36 years. The second subgroup consisted of 54 subjects of the age 14 through 18 years with the mean age of 15.4 years. The last subgroup consisted of 30 subjects of the age 18 years and above with the mean age of 21.35 years. The treated group was also divided into three subgroups by the age. The first subgroup consisted of 145 subjects of the age 14 years and under with the mean age of 12.91 years. The second subgroup consisted of 166 subjects of the age 14 through 18 years with the mean age of 15.64 years. The last subgroup consisted of 47 subjects of the age 18 years and above with the mean age of 21.61 years. Cephalometric films of the sample were traced. Measurements were made to a hundredth using a program specifically prepared for this study, and the results were entered into a 486DX PC. Means and Standard deviations of all the veriables were calculated for each group. Correlation coefficients between pertinent variables were calculated. Significance tests on those coefficients, one-way ANOVA and t-tests between variables or groups were performed. On the basis of the results studied above, certain subjects were selected from the control and the treated groups to locate the proper position of the occlusal plane, and designated as the optimal occluaion group. The subjects of this optimal occlusion group had 1-3 mm overbite, 1-3 mm of overjet and less than 1.75 mm of curve of Spee. A total subjects of 187 in this group consisted 104 treated subjects and 83 control group. Regression analysis was carried out between VDR and LOM, and regression equations were tabulated for this optimal occlusion group. The results were as follows : 1. Highly significant correlations were observed between various variables useful for identifying vertical component of skeletal frame, but any one particular variable did not accurately indicate the magnitude of anterior vertical overbite. 2. Of the variables useful identifying vertical component of skeletal frame, The VDR showed the highest correlation to the LOM. 3. Of the total sample, 80 percent had overbite within the normal range, irrespective of VDR. 4. The optimal occlusion group was divided into 9 subgroups by the age and the anteroposterior skeletal pattern, and correlation coefficient and determination coefficient between VDR and LOM of each group were calculated. Correlation coefficients and determination coefficients were found to be significantly high in all groups. 5. Regression equation was induced for each of the optimal occlusion group to find proper LOM according to the VDR. 6. It was found that the mean value of the cant of occlusal plane itself is not enough for a diagnosis and a treatment plan. Rather, It is very important to locate the proper occlusal plane for an Individual skeletal pattern.

• Pediatric Infection and Vaccine
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• v.19 no.2
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• pp.55-60
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• 2012

Purpose: We conducted the immunoassay of pertussis according to ages, in order to evaluate protective immunity against pertussis in Korean populations. Methods: Healthy subjects were enrolled at four university hospitals in Korea. The subjects were grouped as seven age groups (every 10 years). Antibodies against pertussis toxin (PT) in sera were measured by enzyme linked immunosorbent assay (ELISA) kits. Geometric mean concentrations (GMC) of antibodies and the ratios of the subjects with seroprotective antibody levels were determined. The subjects with antibody titers ${\geq}24.0EU/mL$ were considered to seroprotective as the manufacturer's protocol. Results: Total 1,605 subjects (age: 2 months-65 years) participated in this study, and their GMC was $56.16{\pm}50.54EU/mL$. Among seven age groups, age group <11 year showed the highest GMC ($64.78{\pm}53.24EU/mL$) (P<0.001). In the analysis of the ratios of the subjects with seroprotective antibody titers, 68.2% of the subjects were proven to seroprotective, and age group <11 year also showed the highest ratio (76.5%) (P<0.001). Conclusions: We found that adolescences or adults (age group ${\geq}11$ year) showed lower levels of antibody against pertussis and lower ratio of the subjects with seroprotective antibody titers than children (age group <11 year).

• Journal of the Korean Society of Food Science and Nutrition
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• v.35 no.1
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• pp.68-77
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• 2006

This study was peformed to document the association between nutrient intakes, body mass index (BMI), waist/hip ratio (WHR), and a major risk factor for chronic diseases. A three-day dietary intake survey, using a 24 hour recall method, was obtained from 187 subjects aged 46 to 84 (mean age 65.3) living in Wando island area. The average daily mean energy intakes were 1869.0 kcal for male and 1943.9 kcal for female, respectively. Daily intakes of protein for male and female were 28.0 and 30.4 g, and those of fat were 31.5 and 28.51 g, respectively Carbohydrate dependency was decreased with age. Protein dependency was increased with age. The mean intakes of energy, protein, Vit. A, Vit. D, Vit. E, Ca, Zn did not meet Korean RDA for elderly. The level of serum triglyceride was higher in males than in females and showed the tendency to increase with age in both sexes, whereas HDL-cholesterol tended to decrease with age in both sexes. The levels of serum total-cholesterol and LDL-cholesterol were significantly higher in males than in females, particularly in the age of $46\~59$ (p<0.05). The level of atherogenic index (AI) was significantly higher in females than in males, particularly in the age of 80 and over (p<0.05) Based on these results, it is evident that people in island area did not consume enough nutrient. Specially, dietary intake of protein was not adequate. This study implies that triglyceride, total-cholesterol, LDL-cholesterol, AI were increased with increasing age, BMI and WHR.

• Korea journal of population studies
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• v.15 no.2
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• pp.104-124
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• 1992

형제수, 출산순위, 출산터울, 모성의 출산시 연령 등 가족형성 양상은 아동의 신체적 발육 성장 및 지능발달과 강한 관련성을 보여 왔음이 세계 여러나라 아동을 대상으로 수행된 연구에서 보고되었다. 본 연구는 형제수와 출산순위, 그리고 출산시 모성의 연령은 아동의 신체적 지능적 발달과는 역상관관계를, 출산터울의 길이는 순상관관계를 나타낼 것이라는 가설을 증명하고자 1984년 한국중학생 1,2,3학년 약 46,000명을 대상으로 수행되었다. 지역별 그리고 사회경제적 상태별 비교를 위하여 서울시 고소득층이 주로 거주하는 학구내의 중학교와 저소득층이 거주하는 학구내 중학교 각각 5개를 선정하고 강원도내 전형적 농촌의 중학교 12개를 선정하여 신장, 체중, 좌고, 혈구용적 지능지수를 측정하였다. 이들 측정치들의 평균은 학부모와 담임선생님의 도움으로 작성된 가족형성 변수별로 비교되었으며 다중 희귀분석과 부분상관분석으로 연관성의 통계적 유의성을 검정하였다. 동일연령의 신체적 발육성장 지표들은 도시의 고소득지역 아동들이 가장 우수했으며 다음이 도시저소득 지역 아동이었고 농촌아동이 가장 빈약하였다. 남녀별 신체적 발육지표들의 차이는 연령이 많을수록 더 현저했으며 연령별 지역별 차이는 남학생에게서 더 두드러졌다. 평균 지능지수는 도시고소득지역 남학생들이 월등히 높아 114.8인데 비해 도시저소득지역 남학생들은 106.1, 그리고 농촌 남학생들은 105.3이었다. 남학생보다는 여학생의 지능지수가 낮았는데 이것은 대만 아동들도 여학생이 모든 연령에서 남학생보다 낮았다는 보고와 일치하였다. 한편 도시저소득지역과 농총지역 학생들은 남녀모두 평균지능지수가 비슷하였다. 가족형성변수들은 혼란변수들은 모든 제어했을 경우에도 아동들의 신체적 지능적 발달에 독립적으로 영향을 미쳤다. 발육지표중에 지능지수와 형제수가 가장 가족형성 변수들과의 연관성이 강했다.

• Journal of agricultural medicine and community health
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• v.25 no.2
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• pp.343-352
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• 2000

한국의 농촌 보건의료 문제를 해결 하기위하여 일차보건의료가 도입되었으며 일차보건의료에서 핵심적인 역할을 수행하고 있는 보건진료원의 활동을 분석하였다. 분석 목적은 보건진료원의 일반현황과 보건진료원 활동에 대한 구체적인 분석을 통하여 활동개선 방안을 제시하는데있다. 분석방법은 사회조사 방법을 적용하였으며 조사는 1998년 7월과 11월기간에 구조화된 설문지를 보건진료원 전원에게 송부하여 스스로 작성하게 하였다. 1880명의 보건진료원을 대상으로 설문지를 배포하였으며, 1663명의 응답자가 작성한 설문지가 최종분석되었으므로 분석율은 88.5%였다. 분석결과 보건진료원의 일반현황으로 광역사의 보건진료원 평균 연령은 39.7세이며 시지역 보건진료원의 연령이 군지역보다 높았으며 통계적으로도 유의한 차이가 있었다. 총근무기간도 시지역의 보건진료원의 12.4년-13.6년으로 농촌지역보다 걸었으며 통계적으로도 유의한 차이가 있었다. 보건진료원의 평균 관할 인구수는 901명이었다. 보건진료소 관할지역의 노인인구 및 만성질환자의 분포가 매우 높았다. 보건진료소로부터 민간의료기관이 위치한 거리는 시지역 (7.1-11.3km) 보다 농촌지역이 12.1km로서 지리적 접근성이 시지역보다 낫은 것으로 나타났다. 활동건수분석결과 월평균 가정방문수는 평균 47.8건, 일평균 내소자수는 14.1건 및 일평균 전화상담은 5.2건으로 나타났다. 연령별 활동수준은 40세이상이 4세 이하보다 월평균 가정방문수와 일평균 내소자수가 많았으며 통계적요로도 유의한 차이가 있었다. 경력이 많을수록 일평균가정 방문수 및 전화상담 건수가 많았으며 통계적으로 유의한 차이가 있었다. 근무조건에 대한 만족도는 80%정도로 높았다. 연구결과 보건진료원의 활동지역내 노인인구 및 만성질환자의 비율이 높고 민간의료기관의 지리적 접근성도 낮고, 관할인구규모가 적어서 인구규모를 늘리고 노인 및 만성질환자 건강관리 프로그램의 개발이 더욱 요구되며 농촌지역주민의 건강관리자로서 보건진료원의 활동을 강화할 필요가 있다.