• Title/Summary/Keyword: 편평세포

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Case Report of Squamous Cell Carcinoma arising in an Oral Lichen Planus and Literature Investigation (구강편평태선 환자에서 발생한 암종의 증례보고 및 문헌 고찰)

  • Lim, Hyun-Dae;Lee, You-Mee
    • Journal of Oral Medicine and Pain
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    • v.34 no.1
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    • pp.49-54
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    • 2009
  • Lichen planus is a relatively common chronic inflammatory disease involving the skin and mucous membranes showing small flat polygonal papules. The accurate etiology is unknown but it's suggested that cell-mediated immune response to an induced antigenic changes in skin or mucosa. Oral lichen planus was regarded as an benign lesion but oral lichen planus was classified as premalignant lesion by WHO criteria. It was not known that progress of malignat transmmission in the the patient with oral lichen planus, and chronic inflammatory disease including oral lichen planus showed malignacy in oral cancer unrelated common risk factors(Ex: tabacco, alcohol). Although malignant development in the patient with oral liche planus was various greatly in the literature, from 0.5% upward to 5%. It has been reported that a specific clinical type of oral lichen planus, hyperkeratotic or erosive had a higher chance of transformation into an squamous carcinoma. Clinician has to follow-up check of at least one or two visit per year to detect of malignancy of oral lichen planus and improved prognosis with squamous cell carcinoma. At this case with the middle aged women with squamous cell carcinoma developed from oral lichen planus of more than a decade of persisting, we try to discuss the malignacy of oral lichen planus and cosideration with follow-up.

A Case of Combined Small Cell Carcinoma with Non-Small Cell Lung Carcinoma, Adenocarcinoma and Squamous Cell Carcinoma (편평상피세포암종과 선암종이 동반된 복합형 소세포암종(Combined Small Cell Carcinoma) 1예)

  • Park, Hye-Jung;Mun, Yeung-Chul;Yu, Sung-Keun;Shin, Kyeong-Cheol;Chung, Jin-Hong;Lee, Kwan-Ho;Kim, Mi-Jin;Lee, Jung-Cheul
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.1
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    • pp.72-77
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    • 2000
  • A proper pathologic diagnosis of small cell lung cancer(SCLC) is essential for the application of aggressive treatment modalities. However, various authors have suggested several subtypes of SCLC based on morphological features. Among them, the incidence of small cell lung cancer(SCLC) combined with squamous cell and/or adenocarcinoma, represents less than 1% to 3% of all SCLC tumors. Because of the rarity of SCLC combined with squamous cell and/or adenocarcinoma, very little is known about its clinical characteristics and response to therapy. We report a case of SCLC combined with squamous cell and adenocarcinoma in a 68 year old male who experienced pneumonectomy of the left lung.

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Staining patterns of squamous cell carcinomas of the larynx by monoclonal anti-cytokeratin antibodies (Monoclonal anticytokeratin antibodies 에 의한 후두편평세포암의 발현양상)

  • 도남용;전세영;이성재;최봉남
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1993.05a
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    • pp.88-88
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    • 1993
  • Immunohistochemical staining for keratin proteins may be useful as a diagnostic parameter in head and neck neoplasm. Our study evaluates the keratin antibody staining properties of normal tissues and squamous cell carcinoma of the vocal folds from surgical procedures performed on 27 cases. In normal epithelia, low molecular weight cytokeratins were strongly positive in basal layer but apparently reduced in suprabasal layers and completely negative in superficial layer. In invasive squamous cell carcinomas, low molecular weight anti-ck Ab were positive in all carcinoma cells of poorly differentiated carcinomas. On the other hand, high molecular weight anti-ck Ab were positive in almost carcinoma cells of well differentiated carcinomas.

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