• Title/Summary/Keyword: 특성 모델 검증

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Ex Vivo Raman Spectroscopy Measurement of a Mouse Model of Alzheimer's Disease (라만 기반 치매 모델의 뇌조직 분광 특성 측정)

  • Ko, Kwanhwi;Seo, Younghee;Im, Seongmin;Lee, Hongki;Park, Ji Young;Chang, Won Seok;Kim, Donghyun
    • Korean Journal of Optics and Photonics
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    • v.33 no.6
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    • pp.331-337
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    • 2022
  • Raman spectroscopy is an optical technique that can identify molecules in a label-free manner, and is therefore heavily investigated in various areas ranging from biomedical engineering to materials science. Probe-based Raman spectroscopy can perform minimally invasive chemical analysis, and thus has potential as a real-time diagnostic tool during surgery. In this study, Raman experimentation was calibrated by examining the Raman shifts with respect to the concentrations of chemical substances. Raman signal characteristics, targeted for normal mice and cerebral tissues of the 5xFAD dementia mutant model with accumulated amyloid beta plaques, were measured and analyzed to explore the possibility of diagnosis of Alzheimer's disease. The application to the diagnosis of dementia was cross-validated by measuring Raman signals of amyloid beta. The results suggest the potential of Raman spectroscopy as a diagnostic tool that may be useful in various areas of application.

Characteristics of Water Level and Velocity Changes due to the Propagation of Bore (단파의 전파에 따른 수위 및 유속변화의 특성에 관한 연구)

  • Lee, Kwang Ho;Kim, Do Sam;Yeh, Harry
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.5B
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    • pp.575-589
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    • 2008
  • In the present work, we investigate the hydrodynamic behavior of a turbulent bore, such as tsunami bore and tidal bore, generated by the removal of a gate with water impounded on one side. The bore generation system is similar to that used in a general dam-break problem. In order to the numerical simulation of the formation and propagation of a bore, we consider the incompressible flows of two immiscible fluids, liquid and gas, governed by the Navier-Stokes equations. The interface tracking between two fluids is achieved by the volume-of-fluid (VOF) technique and the M-type cubic interpolated propagation (MCIP) scheme is used to solve the Navier-Stokes equations. The MCIP method is a low diffusive and stable scheme and is generally extended the original one-dimensional CIP to higher dimensions, using a fractional step technique. Further, large eddy simulation (LES) closure scheme, a cost-effective approach to turbulence simulation, is used to predict the evolution of quantities associated with turbulence. In order to verify the applicability of the developed numerical model to the bore simulation, laboratory experiments are performed in a wave tank. Comparisons are made between the numerical results by the present model and the experimental data and good agreement is achieved.

A Numerical Study on the Effect of Steel Casing on Bearing Capacity of Drilled Shafts for Marine Bridges (수치해석을 이용한 국내 해상교량 현장타설말뚝의 강관지지효과)

  • Lee, Juhyung;Shin, Hyu-Soung;Park, Minkyung;Park, Jae Hyun;Kwak, Kiseok
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.3C
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    • pp.149-158
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    • 2008
  • This study is concerned with the characteristics of the behavior of drilled shafts with steel casing, a material that is used for large bridge foundations in Korea, and especially for weak submerged ground conditions. The effect of steel casing on bearing capacity of drilled shafts was also verified in this study. Three large drilled shafts with 1.8, 2.4, 3.0m diameter respectively were selected, and 3-D finite element analysis has been undertaken on the following three models: 1) drilled shafts without steel casing, 2) drilled shafts with steel casing, 3) steel-concrete composite drilled shafts. Interface element between concrete core and steel casing was taken into account, and ground conditions and load combinations were applied which had been considered in the fields. Detailed characteristics of the stress and displacement distributions were evaluated to understand the characteristics of the behavior of the drilled shafts. Based on the study performed, the steel casing used as load-carrying materials in the drilled shafts can reduce the horizontal and vertical displacement of drilled shafts by 32~37% and 15~19% respectively compared with drilled shafts without steel casing.

Factors Affecting Adoption Intention of Autonomous Vehicle (자율주행 자동차 사용의도에 영향을 미치는 요인)

  • Beck, Sung-yon;Lee, So-young
    • Journal of Venture Innovation
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    • v.5 no.4
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    • pp.91-108
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    • 2022
  • This study is an empirical analysis regarding what kind of factors affect the intention to use autonomous vehicles. For the empirical analysis the research model was derived from value-based adoption model base and integrated some aspects that only autonomous vehicles have. At default variables of VAM are usefulness, enjoyment, technicality, perceived cost, some autonomous vehicle related variables were added, and those are convenience, safety, security, social influence. A survey was done in order to empirically analyze with this research model, and 216 valid survey answers were chosen to analyze. Empirical analysis was done by structural equation using AMOS24. The result of empirical analysis were as follows. Variables usefulness, enjoyment, safety, security had a significant positive effect on perceived value. Technicality and perceived cost had a significant negative effect of perceived value. In addition, security and social influence had no significant effect on perceived value. Furthermore, perceived value had significant positive effect on intention to use. Among the variables that came out to be significantly positive, the most influencing variable was safety, followed by convenience, perceived cost, enjoyment, usefulness and then technicality. In addition, the analysis of mediating effect of perceived value shows that usefulness, enjoyment, convenience, safety, technicality, perceived cost had mediating role towards intention to use. However, security and social influence had no siginificant mediating effect towards intention to use. Considering all these research results this study has provided theoretical and practical implications to researchers on the intention to use autonomous vehicles.

The Effect of Team Characteristics of Technology-based Startup Programs on Patent Performance: Focusing on Team Diversity (기술기반 창업 프로그램의 팀 특성이 특허 성과에 미치는 효과 분석: 팀 다양성을 중심으로)

  • Lee, Jai Ho;Sohn, Youngwoo;Han, Jung Wha;Lee, Sang-Myung
    • Knowledge Management Research
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    • v.25 no.1
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    • pp.21-41
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    • 2024
  • The global Industry has been shaped by start-ups that originated with knowledge-based innovative strategies or technologies in the 21st century. Specifically, laboratory start-ups that rely on research papers or patents for new technology development are recognized for their high survival rate and the creation of employment opportunities. Our study concentrated on 'I-Corps', which also introduced in Korea, standing for innovation corps is a laboratory startup program launched in 2011 by the NSF(National Research Foundation) to commercialize R&D results and foster entrepreneurship as part of the policy to build a start-up system at the national innovation level. In this study, we proposed and empirically tested a research model focusing on teams participating in the I-Corps program to determine how startup team diversity, among the team characteristics of laboratory startups, affected patent performance. As a result of the analysis, among the proposed variables, age diversity, educational background diversity, and value diversity had a significant impact on patent performance. The results of this study are expected to further strengthen the theoretical and practical foundations of researchers or practitioners of the I-Corps program, as well as related areas involving technology & laboratory startups, intellectual property and knowledge management fields in the future.

A Study on Effective Software Education Model by Disability Type for Youth

  • Lee, Hyun Ju;Lee, Won Joo;Jung, Hoe Kyung
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.10
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    • pp.261-268
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    • 2020
  • In this paper, we propose an effective software education model for youths with disability. This software education model consists of a four-step process. In the first step, it draws the education curriculum of the software education for different types of disabled youths based on the results of comparative analysis of software education field in special education curriculum. In the second step, it suggests achievement standards for effective software education for the disabled students by classifying students with intellectual disabilities and visual, hearing, and physical disabilities without any multiple disabilities. In the third step, the study developed a modular textbook comprised of unplugged activities using coding robot Albert, physical computing, and block/text coding with the reflection of the characteristic of each type of disability. In the fourth step, it applied the textbook to the school field and educated disabled students focusing on experience to allow them to think logically and by stages about different problems they face in daily lives. In addition, by analyzing the results of youths' performance evaluation and surveys, it was shown that 82.3% of developmental disabilities, 78.8% of visual impairments, 90.9% of hearing impairments, and 78.8% of physically disabilities achieved achievements above the "medium" level. These results prove that the software education model for youths with disabilities proposed in this paper is very effective in improving computational chinking of youths with disabilities.

A Study on Effective Methods of Polygon Modeling through Modeling Process-Related System (모델링 공정 연계 시스템을 통한 효율적 폴리곤 모델링 기법에 대한 탐구)

  • Kim, Sang-Don;Lee, Hyun-Seok
    • Cartoon and Animation Studies
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    • s.37
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    • pp.143-158
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    • 2014
  • In the modeling processes of 3D computer animation, methods to build optimal work conditions to realize real forms for more efficient works have been advanced. Digital sculpting software, published in 1999, ZBrush has been positioned as an essential factor in character model work requiring of realistic descriptions through different manufacturing methods from previous modeling work processes and easy shape realization. Their functional areas are expanding. So, in this production case paper, as a method to product more optimized animation character models, the efficiency of production method linking digital sculpting software (Z-Brush) and animation production software (Maya) was deliberated and its consequences and implications are suggested. To this end, first the technical features of polygon modeling and Retopology were reviewed. Second, based on it, the efficiency of animation character modeling work processes through step linking ZBrush and Maya suggested in this paper was analyzed. Third, based on the features drawn before, in order to prove the hypothesis on modeling optimization method suggested in this paper, the production process of character Dumvee from a short animation film, 'Cula & Mina' was analyzed as an example. Through this study, it was found that technical approach easiness and high level of completion could be realized through two software linked work processes. This study is considered to be a reference for optimizing production process of related industries or modeling-related classes by deliberating different modeling process linked systems.

Seismic Analysis of the Reflective Metal Insulation for Thermal Shielding of Main Equipments of Nuclear Power Plants (원전 설비 열차폐를 위한 반사형 금속단열재의 내진 해석)

  • Kim, Seung-Hyeon;Rhee, Huinam
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.6
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    • pp.166-172
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    • 2016
  • This paper deals with the seismic qualification of the reflective metal insulation for thermal shielding that is installed on the outer surfaces of the main equipment of the primary coolant system of a nuclear power plant. A small-scale model of the reactor pressure vessel, which has equivalent dynamic characteristics, was designed to be tested in domestic seismic testing facilities in the future. In this study, seismic analysis of the small-scale model installed with metal insulation was performed using equivalent static analysis and response spectrum analysis. The required Response Spectrum for main equipment of the primary coolant system of APR-1400 plant were considered to establish the enveloping response spectrum, which was applied to the seismic analysis model. The results from two seismic analysis methods were compared to show the structural adequacy of the metal insulator design against a safe shutdown earthquake. This study will form the basis for the seismic testing to support the seismic qualification of the reflective metal insulator.

Icing Wind Tunnel Tests to Improve the Surface Roughness Model for Icing Simulations (착빙 해석의 표면 거칠기 모델 개선을 위한 착빙 풍동시험 연구)

  • Son, Chankyu;Min, Seungin;Kim, Taeseong;Kim, Sun-Tae;Yee, Kwanjung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.46 no.8
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    • pp.611-620
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    • 2018
  • For the past decades, the analytic model for distributed surface roughness has been developed to improve the accuracy of the icing simulation code. However, it remains limitations to validate the developed model and determine the empirical parameters due to the absence of the quantitative experimental data which were focused on the surface state. To this end, the experimental study conducted to analyze the ice covered surface state from a micro-perspective. Above all, the tendency of the smooth zone width which occurs near the stagnation point has been quantitatively analyzed. It is observed that the smooth zone width is increased as growing the ambient temperature and freestream velocity. Next, the characteristics of the ice covered surface under rime and glaze ice have been analyzed. For rime ice conditions, ice elements are developed as the opaque circular corn in the opposite direction of freestream. The height and interval of each circular corn are increased as rising the ambient temperature. For glaze ice conditions, numerous lumps of translucent ice can be observed. This is because the beads formed by gravity concentrate and froze on the lower surface.

A Study on the Integration Model of Continuous Intention to Collect K-POP Records Using SNS (SNS를 활용한 K-POP 기록물 수집활동에 대한 지속의도 통합모델 연구)

  • Kim, Geon;Yun, Sung-uk;Kim, Hyun-Tae
    • Journal of Digital Convergence
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    • v.18 no.5
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    • pp.441-453
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    • 2020
  • This study conducted a questionnaire survey on SNS users who are conducting K-POP record collection activities using SNS and verified factors affecting the intention to continue K-POP record collection activities. The main methods of analysis were exploratory factor analysis, confirmatory factor analysis, correlation analysis, and path analysis using SPSS 21.0 program and AMOS 21.0 program. The results are summarized as follows. First, compatibility for K-POP record collection activities through SNS has a positive effect on perceived usefulness, and observability also has a positive effect on perceived usefulness and perceived ease of use. Second, perceived ease of use for K-POP records collection using SNS has a positive effect on perceived usefulness. Third, perceived usefulness and perceived ease of use for K-POP records collection using SNS have a positive effect on continuous intention of K-POP records collection activity through SNS. As a result of this study, it suggests that the intention to continue the collection activities of K-POP records using SNS can be explained through the integration of innovation diffusion theory and technology acceptance model.