• Proceedings of the SCSK Conference
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• 1996.07a
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• pp.10-14
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• 1996

최근 오존층의 파괴로 인한 지구 자외선량의 증가로 피부암 및 광노화의 발생가능성이 증가되고있다. 광노화의 주요한 현상중의 하나는 탄력섬유상 물질이 축적되는 일광탄력 섬유증이다. 자외선은 탄력소 유전자의 전사과정증가를 유도하며 결국 비정상적인 탄력소의 증가를 유발한다는 보고가 있다. 본 연구에서는 피부 섬유아세포 및 각질형성세포를 배양하여 자외선이 탄력소 유전자발현에 미치는 영향 및 전사조절인자에 미치는 영향을 알아보고자 하였다. 피부섬유아세포에 UVB를 30mJ-200J/m 조사하여 nothern blotting한 결과 UV양이 증가함에 따라 탄력소 전사물이 증가되었고, 1001/$m^2$ 에서 최대의 증가를 보였다. 탄력소 promoter와 CAT을 접합시킨 pEP62 vector을 섬유아세포에 형질전환 시키고 UV에 의한 Promoter 활성을 본 결과 UV조사량이 증가할수록 활성이 증가되었고 200J/$m^2$ 에서 대조군에 비해 5배의 활성 증가를 보였다. 이 system에 광노화 억제물질로 알려진 retinoid를 5 $\times$ $10^{-6}$M처리하였을 때 UV에 의한 탄력소 promoter활성을 약 1/3로 감소시켰다. 각질 형성세포에서 UVB에 의한 transcription factor의 활성을 mobility shift assay에 의해 조사한 결과 AP-1 및 NFkB가 활성화됨을 볼 수 있었다.

• International Area Studies Review
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• v.21 no.4
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• pp.3-17
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• 2017

The purpose of the paper is to suggest the empirical evidences for the effects of factor prices on the export performance in the Korean manufacturing industries during the period 1975:1-2016:4. The paper is to set up the error correction model derived from the autoregressive distributed lag scheme and to estimate the factor price elasticities of export in the 8 manufacturing industries. The real wage, interest and import price index elasticities of export all were estimated to be statistically significant at 1% level in the most industries with showing negative signs as expected. And the real wage elasticity proved to likely be smaller as the industries become more capital-intensive while the import price index elasticity tended to become larger in industries with larger ratio of imported intermediate goods to output. The empirical results suggest that the declines in input factor prices since the foreign exchange crisis in the end of 1997 have positive effects on the export performance in the Korean manufacturing industries.

• The Journal of the Convergence on Culture Technology
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• v.4 no.3
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• pp.275-285
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• 2018

The purpose of this study was to examine the effect of the application of elastic compression stocking during the stand for a long hours of works on edema and pain of lower extremities in ward nurses. Methods: The experimental group was subjected to elastic pressure tights for 5 days from the beginning to the end, and lower extremity edema and ankle and calf circumference were measured. Results: "There are significant differences in lower extremity pain the experimental group of elastic compression stocking and control group" was supported(p<.001). "There are significant differences in lower extremity edema the experimental group of elastic compression stocking and control group" was supported (p<.001). Conclusion: Applying elastic pressure stocking as a method of management of lower extremity pain and lower extremity edema in ward nurses, relieving symptoms related to lower extremity pain and lower extremity edema during work. This is an effective way to prevent problems and improve the health of nurses and provide quality nursing care.

• Journal of Korean Society of Transportation
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• v.26 no.1
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• pp.51-63
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• 2008

Jeju-Mainland demand for air passenger is variated by the season because most of the demands stem from the leisure travel. This research is to estimate the econometrics demand models(A simple time series model and the partial adjustment model) and elasticities of each models for the Jeju-Mainland domestic routes air travel market using the time series aggregate data between the year 1996 and 2005. As the result of estimating, income elasticity was evaluated to be elastic(1.55) and fare elasticity was inelastic(-0.49${\sim}$-0.59) for A simple time series models. In the partial adjustment model's case, income elasticity was evaluated to be inelastic(0.51) in short-run whereas it was evaluated to be elastic(1.88) in long-run. Fare elasticity was evaluated to be inelastic in short-run(high-demand season: -0.13, slack season: -0.20) and long-run(high-demand season: -0.48, slack season: -0.72).

• Journal of the Society of Cosmetic Scientists of Korea
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• v.22 no.1
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• pp.60-69
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• 1996

3-APPA는 생체내 물질 Υ-amino butyric acid와 유사한 구조를 갖는 물질로서 human fibroblasts 3-dimensional culture system 등의 in vitro 시험에서 collagen 합성촉진 효과, 세포증식 효과를 나타내며, hairless mouse를 이용한 동물시험에서도 collagen 합성이 증가되는 것으로 보고된 바 있다. 또한 피부 안정성에서도 우수한 결과를 보여줌으로서 화장품 분야에서 새로운 노화억제 물질로서 주목을 받게 되었다. 본 시험에서는 180명의 피검자를 대상으로 3개월간의 임상시험을 통하여 새로운 노화억제 물질인 3-APPA의 효능을 기존의 GABA 유사물질, aminopropane sulfonic acid와 비교하였다. 본 시험은 double-blind, randomized, vehicle-controlled clinical study로서 180명의 피검자를 APSA군, 3-APPA군, vehicle군으로 분류한 후 3개월간 매일 저녁 취침 전, 안면에 시험제품을 사용하도록 하였으며, 사용 전, 사용 1주후, 2주후, 6주후, 12주후 5회 설문지를 통하여 피부상태를 조사하였다. 각 설문내용은 피부 건조도, 피부 탄력도, 피부 주름량, 피부 윤기도, 피부 거칠기 정도에 대한 5개 질문으로 구성된 효능에 관한 질문과 흡수정도, 끈적임, 매끄러움, 보습력, 보습지속성, 전체적인 사용감에 대한 6개 질문으로 구성된 사용성에 관한 것이었다. 각 질문에 대하여는 매우 좋음 1점, 좋은 2점, 보통임 3점, 나쁨 4점, 매우 나쁨 5점 사이에서 답할 수 있도록 하였다. 시험 결과 APSA군은 6주와 12주후 피부 건조도, 피부 거칠기 항목에서 사용전에 비하여 유의한 차이를 나타내었다. 3-APPA군은 6주후 피부 건조도, 피부 거칠기, 피부 탄력도 항목에서 시료사용전에 비해 유의한 차이를 나타내었으며 12주후에는 피부 건조도, 피부 탄력도, 피부 윤기도, 피부 거칠기 항목에서 유의한 차이를 나타내었다. 12주후 APSA군은 피부 주름, 피부 탄력도 항목에서 vehicle 사용 피검자군에 비하여 유의적인 차이를 나타내었으나 3-APPA군은 피부 탄력도, 피부 주름량, 피부 윤기 항목에서 vehicle군에 비하여 유의적인 차이를 나타내었다. 결론적으로 3-APPA와 APSA 사이에 유의적인 차이가 있지는 않았으나 3-APPA군은 APSA군에 비하여 6주, 12주에서 사용전과 유의한 차이를 나타내는 항목이 많았으며 12주에서 vehicle과 유의적인 차이를 나타내는 항목도 많으므로 3-APPA가 APSA 보다 광범위한 피부노화 억제 효과를 갖는 물질이라고 할 수 있다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.12
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• pp.5805-5810
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• 2011

This study aims to provide fundamental data to develop anti-aging programs in the aspect of skin care. To attain the goal, manual therapy and low-power laser therapy were conducted separately to 8 women inthe 40's and 50's. They received the facial massage total 8 times twice a week for 4 weeks. According to the result of calculating the average and standard deviation by measuring skin elasticity of the area below their eyes and cheeks and also melanin around eyes and cheeks and conducting comparative analysis, both groups showed significant increase in elasticity and their melanin decreased significantly. The low-power laser therapy showed higher values than the manual therapy both in elasticity increase and melanin reduction; thus, it was analyzed that the low-power laser therapy more highly affects skin elasticity and the amount of melanin in facial skin is greater than that in manual therapy. Therefore, it was analyzed that skin care using low level laser can be significant in anti-aging of facial skin and can be utilized as a program for a new type of skin care.

• Proceedings of the Korean Society of Disaster Information Conference
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• 2022.10a
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• pp.75-76
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• 2022

본 연구는 기업과 그 기업이 속한 사회에서 사업을 영위하면서 자연재해의 발생이나 COVID-19와 같은 감염병의 유행으로 조직의 업무 중단이 발생하고 난 뒤 다시 사업을 재개하는 데에는 회복탄력성이 중요하다. 기업의 회복탄력성은 기업을 경영하는데 필요한 수많은 요소와 관련이 있다. 또한 기업과 연결된 많은 네트워크와 인프라에 의존하고 있다. 회복탄력성은 재난을 당한 뒤에 다시 사업을 영위하는 능력이라 할 수 있다. 재난에 대응하는 저항의 능력 보다는 기업의 핵심 기능이 단기간에 연속성을 확보하는데 그 의의가 있다고 하겠다. 이를 위하여 기업의 재난에 대한 '예방 활동', '대비 활동', '대응 활동'을 필수 요소로 삼고 있다. 그 외에 회복탄력성에 영향을 미치는 요인을 연구하기 위하여, 여유 자원, 협력관계, 전략적 유연성, 혁신성, 기술 변화 대응력이 조직역량에 미치는 영향력을 파악하고, 조직역량이 기업의 회복탄력성에 기여하는 정도를 파악하고자 하였다. (권재득, 2018). 회복탄력성의 미치는 추가요인인 외적 효과 분석에 대한 연구를 제안한다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.3
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• pp.165-174
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• 2017

The purpose of this study was to investigate the effect of three sub-factors of family resilience on family strength as perceived by university students. The subjects were 409 university students in G area. This study investigated the perception level of family resilience and family strength, the difference in the family strength between the resilient group and non-resilient group and the effect of family resilience on family strength. The study results were as follows: First, the students' perceptions of family resilience and family strength were moderately high. Second, the students with positive perceptions of all three family resilience sub-factors (resilient group) also had a higher perceived family strength than the non-resilient group. Third, gender was found to have an influence on family strength, with the male students having a higher perceived family strength. All three sub-factors of family resilience were statistically significant and the belief system and organizational pattern had a strong influence on the family strength. In particular, the belief system was the most powerful factor affecting the family strength. The role clarity, family cohesion and family resource of the family organizational pattern were significant factors. Moreover, collaborative problem solving and open emotional communication also had a significant influence on family strength.

• Management & Information Systems Review
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• v.36 no.4
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• pp.81-102
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• 2017

This study examined the income and price elasticities of tourism demand model by using the ARDL models. This paper used the ARDL & ARDL-RECM model based on the annual number of tourists arrivals, GDP and CPI including tourists from the US, Japan and China entering Korea. First, the income elasticity of the US was inelastic and insensitive necessities for long-run US tourists in the ARDL model. China's income elasticity was elastically sensitive luxuries. Second, the US and China's own price elasticities were very elastic to tourism demand in both models. Third, the US's cross price elasticity showed the relationship between inelastic positive substitutes and inelastic negative complements in China in ARDL model. The cross price elasticities of the US and China showed inelastic positive substitutes in the ARDL-RECM model. Fourth, the coefficients of the error correction term were such that the actual sign and the expected sign of the US and China coincided with the negative sign in the ARDL-RECM model. Therefore, first, it can be established in a tourist policy or tourism strategy through income elasticity. Second, we can improve the quality and differentiation of products, recognizing that Korea's tourism price is more elastic than other markets through price elasticity.

• Journal of the Korean Society of Radiology
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• v.11 no.4
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• pp.205-212
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• 2017

Chronic diffuse hepatopathy is one of the important clinical tasks to reduce mortality and morbidity due to liver cirrhosis, liver failure, and liver cancer. The purpose of this study was to evaluate the criteria for predicting liver and chronic liver disease using Fibroscan based on ultrasound diagnosis. Serum and liver stiffness measurement(kPa) were analyzed in 280 patients and cut-off values of liver stiffness measurement for predicting fatty liver and chronic diffuse hepatopathy were determined using ROC curve analysis. Bilirubin and PT(prothrombin time) were not related to disease prediction(p=0.243, p=0.115). Serum glucose and triglyceride levels were significantly higher in the liver (p<0.05). The cut-off value for predicting chronic diffuse hepatopathy was determined as 10.3 kPa(AUC 0.98, sensitivity 94.94%, specificity 94.93%) in the order of control group, fatty liver and chronic diffuse hepatopathy. Therefore, it will be used as a primary tool for the diagnosis of chronic liver disease patients with quantitative evaluation.